Gladfelter Lab
@gladfelterlab.bsky.social
Scientists using microscopes, math, physics and fun to discover how cells work @Duke Cell Biology/BME. https://gladfelterlab.net
You're probably already doing science advocacy — you just might not call it that. Our new commentary (www.nature.com/articles/s41...) makes the case that every scientist has a role, and that advocacy takes many forms. Find and embrace yours! @natcellbio.nature.com @vfarm15.bsky.social
Every scientist has a role in advocacy - Nature Cell Biology
In this Comment, we call on scientists to share their stories. Through casual conversation or prepared presentations, with images or essays, scientists can advocate for their research and reach taxpay...
www.nature.com
July 26, 2026 at 3:52 PM
You're probably already doing science advocacy — you just might not call it that. Our new commentary (www.nature.com/articles/s41...) makes the case that every scientist has a role, and that advocacy takes many forms. Find and embrace yours! @natcellbio.nature.com @vfarm15.bsky.social
Excited to share the newest piece of the puzzle of RNA properties in condensates! www.molbiolcell.org/doi/10.1091/... by newly minted Dr. Sierra Cole, published in MBoC condensates special issue
Sequence and structure of protein binding sites in RNA impact biomolecular condensates | Molecular Biology of the Cell
Biomolecular condensates are central to subcellular compartmentalization and RNA regulation.
In the multinucleate fungus Ashbya gossypii, condensates composed of Whi3 protein
and CLN3 mRNA help ensure...
www.molbiolcell.org
June 9, 2026 at 10:05 PM
Excited to share the newest piece of the puzzle of RNA properties in condensates! www.molbiolcell.org/doi/10.1091/... by newly minted Dr. Sierra Cole, published in MBoC condensates special issue
A wonderful write up of what motivates our work! madeforthis.duke.edu/stories/lear...
Learning the Secrets of Mega-Cells - Made for This: The Duke Campaign
BY ADRIANA V. DIFRANCO What do fungi in the forest and human placentas have in common? It sounds like a riddle, but it’s actually a fascinating biological conundrum. Fungi and placentas have two of th...
madeforthis.duke.edu
April 23, 2026 at 5:36 PM
A wonderful write up of what motivates our work! madeforthis.duke.edu/stories/lear...
Condensates are powerful ways to break symmetry and cells do remarkable things with them. Here we show that in a multinucleate fungus, a condensate regulates translation of a cyclin and a formin in distinct locations.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
RNA-specific local translation is patterned by condensates for multinucleate cell growth - Nature Cell Biology
Geisterfer, Jalihal et al. show spatially distinct effects of Whi3 condensates on target translation in Ashbya syncytia. In vitro, translation is enriched at condensate–solute interfaces but repressed...
www.nature.com
March 8, 2026 at 6:05 PM
Condensates are powerful ways to break symmetry and cells do remarkable things with them. Here we show that in a multinucleate fungus, a condensate regulates translation of a cyclin and a formin in distinct locations.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Gladfelter Lab
@gladfelterlab.bsky.social kicking off the first SRC of 2026 with an amazing turnout at #PhaseTSRC. Special thanks to our organizers for their leadership in this brand-new conference topic, including lead organizer @umassmdlab.bsky.social
January 12, 2026 at 5:05 PM
@gladfelterlab.bsky.social kicking off the first SRC of 2026 with an amazing turnout at #PhaseTSRC. Special thanks to our organizers for their leadership in this brand-new conference topic, including lead organizer @umassmdlab.bsky.social
Reposted by Gladfelter Lab
How can you tackle emerging questions in cellular organisation, adaptation, and robustness? Join #EESPhaseSeparation! 🧬🦠
Bringing together scientists from diverse fields to foster new discoveries in condensate biology.
Submit your abstract by 10 Feb: s.embl.org/ees26-08-bl
📅 19 – 22 May 2026
Bringing together scientists from diverse fields to foster new discoveries in condensate biology.
Submit your abstract by 10 Feb: s.embl.org/ees26-08-bl
📅 19 – 22 May 2026
December 17, 2025 at 9:22 AM
How can you tackle emerging questions in cellular organisation, adaptation, and robustness? Join #EESPhaseSeparation! 🧬🦠
Bringing together scientists from diverse fields to foster new discoveries in condensate biology.
Submit your abstract by 10 Feb: s.embl.org/ees26-08-bl
📅 19 – 22 May 2026
Bringing together scientists from diverse fields to foster new discoveries in condensate biology.
Submit your abstract by 10 Feb: s.embl.org/ees26-08-bl
📅 19 – 22 May 2026
Interested in the MBL Physiology Course in Woods Hole and want to learn more before you apply?
Join myself and Cliff at our Virtual Open House TOMORROW 2–3 PM ET. You will hear what the course experience is like and get all your questions answered.
Register/Join: princeton.zoom.us/j/97673682905
Join myself and Cliff at our Virtual Open House TOMORROW 2–3 PM ET. You will hear what the course experience is like and get all your questions answered.
Register/Join: princeton.zoom.us/j/97673682905
Interested in the MBL Physiology Course and want to learn more before you apply?
Join our Virtual Open House on Tues, Jan 6, 2026 | 2–3 PM ET to meet the team, hear what the course experience is like, and get your questions answered.
🔗 Register/Join: https://go.mbl.edu/r5q
Join our Virtual Open House on Tues, Jan 6, 2026 | 2–3 PM ET to meet the team, hear what the course experience is like, and get your questions answered.
🔗 Register/Join: https://go.mbl.edu/r5q
January 5, 2026 at 7:15 PM
Interested in the MBL Physiology Course in Woods Hole and want to learn more before you apply?
Join myself and Cliff at our Virtual Open House TOMORROW 2–3 PM ET. You will hear what the course experience is like and get all your questions answered.
Register/Join: princeton.zoom.us/j/97673682905
Join myself and Cliff at our Virtual Open House TOMORROW 2–3 PM ET. You will hear what the course experience is like and get all your questions answered.
Register/Join: princeton.zoom.us/j/97673682905
Reposted by Gladfelter Lab
Fantastic ASCB so far! Haven’t even had time to live tweet with all the great talks and catching up with folks. Some science standouts to far have been the Planetary Cell Bio session organized by @gladfelterlab.bsky.social and @robinsall.bsky.social’s beautiful talk on cell migration
December 8, 2025 at 4:32 PM
Fantastic ASCB so far! Haven’t even had time to live tweet with all the great talks and catching up with folks. Some science standouts to far have been the Planetary Cell Bio session organized by @gladfelterlab.bsky.social and @robinsall.bsky.social’s beautiful talk on cell migration
Reposted by Gladfelter Lab
🌍 Heading to #CellBIO2025 meeting @embo.org @ascbiology.bsky.social ? Join us as we continue building Planetary Cell Biology, a cross scale field - from cells to biodiversity. Sunday, Dec 7 | 8:30–9:45 AM EST
Curious? www.youtube.com/@Cells4Plane...
🌱 Join the community: forms.gle/AjQ6dVBL7QT5...
Curious? www.youtube.com/@Cells4Plane...
🌱 Join the community: forms.gle/AjQ6dVBL7QT5...
Cells for Planetary Health Community Registration Form
Following the “Integrating Cell and Planetary Scales to Address Climate Resilience” workshop held in Lisbon in April 2025, we’re launching a new community dedicated to bridging scientific disciplines ...
forms.gle
December 1, 2025 at 2:37 PM
🌍 Heading to #CellBIO2025 meeting @embo.org @ascbiology.bsky.social ? Join us as we continue building Planetary Cell Biology, a cross scale field - from cells to biodiversity. Sunday, Dec 7 | 8:30–9:45 AM EST
Curious? www.youtube.com/@Cells4Plane...
🌱 Join the community: forms.gle/AjQ6dVBL7QT5...
Curious? www.youtube.com/@Cells4Plane...
🌱 Join the community: forms.gle/AjQ6dVBL7QT5...
Reposted by Gladfelter Lab
#Lipid packing and local geometry influence #septin curvature sensing, say Brandy Curtis, Amy Gladfelter @gladfelterlab.bsky.social and colleagues @duke-university.bsky.social: rupress.org/jcb/article/...
#Biochemistry #Cytoskeleton
#Biochemistry #Cytoskeleton
November 10, 2025 at 2:45 PM
#Lipid packing and local geometry influence #septin curvature sensing, say Brandy Curtis, Amy Gladfelter @gladfelterlab.bsky.social and colleagues @duke-university.bsky.social: rupress.org/jcb/article/...
#Biochemistry #Cytoskeleton
#Biochemistry #Cytoskeleton
Delighted to share the latest chapter in the mystery series on how septins sense membrane curvature. Grateful to reviewers for thoughtful critiques and @jcb.org for publishing our work! doi.org/10.1083/jcb....
Lipid packing and local geometry influence septin curvature sensing
Localization of the septin cytoskeleton is controlled by regulatory factors, membrane curvature, and charge. In this study, changes to lipid composition th
doi.org
November 4, 2025 at 4:13 AM
Delighted to share the latest chapter in the mystery series on how septins sense membrane curvature. Grateful to reviewers for thoughtful critiques and @jcb.org for publishing our work! doi.org/10.1083/jcb....
Our paper on the spatial organization of nuclear paraspeckles is out in #PNAS! Excited to see what comes next from the teams of @shrinivaslab.bsky.social and @sneadlab.bsky.social at Northwestern! pnas.org/doi/10.1073/pnas.2504778122
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
pnas.org
August 7, 2025 at 4:10 PM
Our paper on the spatial organization of nuclear paraspeckles is out in #PNAS! Excited to see what comes next from the teams of @shrinivaslab.bsky.social and @sneadlab.bsky.social at Northwestern! pnas.org/doi/10.1073/pnas.2504778122
Reposted by Gladfelter Lab
We are back! 🔬👩🔬👨🔬
Mark your calendars, TCM 2025 is happening September 15th at the Trent Semans Center! 🧠✨
Get ready for an incredible lineup of speakers including Dr. Kris DeMali, Dr. Rae Cho, and Dr. Stefanie Redemann.
🗓️ Registration opens July 7th, don’t miss out!
#TCM2025
Mark your calendars, TCM 2025 is happening September 15th at the Trent Semans Center! 🧠✨
Get ready for an incredible lineup of speakers including Dr. Kris DeMali, Dr. Rae Cho, and Dr. Stefanie Redemann.
🗓️ Registration opens July 7th, don’t miss out!
#TCM2025
June 13, 2025 at 1:31 AM
We are back! 🔬👩🔬👨🔬
Mark your calendars, TCM 2025 is happening September 15th at the Trent Semans Center! 🧠✨
Get ready for an incredible lineup of speakers including Dr. Kris DeMali, Dr. Rae Cho, and Dr. Stefanie Redemann.
🗓️ Registration opens July 7th, don’t miss out!
#TCM2025
Mark your calendars, TCM 2025 is happening September 15th at the Trent Semans Center! 🧠✨
Get ready for an incredible lineup of speakers including Dr. Kris DeMali, Dr. Rae Cho, and Dr. Stefanie Redemann.
🗓️ Registration opens July 7th, don’t miss out!
#TCM2025
Discover the wonder of the fungi in this latest issue of Current Biology 🍄 www.cell.com/curbio/issue...
Current issue: Current Biology
www.cell.com
June 9, 2025 at 4:26 PM
Discover the wonder of the fungi in this latest issue of Current Biology 🍄 www.cell.com/curbio/issue...
Reposted by Gladfelter Lab
Start of 2025 @mblscience.bsky.social Physiology course! This is the second year of Amy @gladfelterlab.bsky.social and I co-Directing this absolutely amazing and life-changing course: www.mbl.edu/education/ad...
June 9, 2025 at 3:03 PM
Start of 2025 @mblscience.bsky.social Physiology course! This is the second year of Amy @gladfelterlab.bsky.social and I co-Directing this absolutely amazing and life-changing course: www.mbl.edu/education/ad...
Amazing start to EMBO workshop Cells4Climate resilience>>https://meetings.embo.org/event/25-climate-resilience>>day 1 energy captured here youtu.be/KFRFSPHdjFM
youtu.be
April 15, 2025 at 8:27 AM
Amazing start to EMBO workshop Cells4Climate resilience>>https://meetings.embo.org/event/25-climate-resilience>>day 1 energy captured here youtu.be/KFRFSPHdjFM
🌍🔬 📣 Please spread the word! Join us!
How can cell biology shape a more resilient planet?
Virtual registration is still open for the EMBO Workshop on Cells 4 Climate Resilience → meetings.embo.org/event/25-cli...
🗓️ Deadline: April 11
🎥 Watch the teaser → youtu.be/8eMJ91udHDs
@embo.org
How can cell biology shape a more resilient planet?
Virtual registration is still open for the EMBO Workshop on Cells 4 Climate Resilience → meetings.embo.org/event/25-cli...
🗓️ Deadline: April 11
🎥 Watch the teaser → youtu.be/8eMJ91udHDs
@embo.org
Your browser does not support or is disabling JavaScript.
meetings.embo.org
April 6, 2025 at 9:42 PM
🌍🔬 📣 Please spread the word! Join us!
How can cell biology shape a more resilient planet?
Virtual registration is still open for the EMBO Workshop on Cells 4 Climate Resilience → meetings.embo.org/event/25-cli...
🗓️ Deadline: April 11
🎥 Watch the teaser → youtu.be/8eMJ91udHDs
@embo.org
How can cell biology shape a more resilient planet?
Virtual registration is still open for the EMBO Workshop on Cells 4 Climate Resilience → meetings.embo.org/event/25-cli...
🗓️ Deadline: April 11
🎥 Watch the teaser → youtu.be/8eMJ91udHDs
@embo.org
What a wonderful time catching us with @meghanriddell.bsky.social in Charolette at the Society for Reproductive Investigation Annual Meeting!
March 28, 2025 at 10:15 PM
What a wonderful time catching us with @meghanriddell.bsky.social in Charolette at the Society for Reproductive Investigation Annual Meeting!
Reposted by Gladfelter Lab
Mónica Bettencourt-Dias @monicabettencourt.bsky.social, Amy Gladfelter @gladfelterlab.bsky.social, Gautam Dey @gautamdey.bsky.social Samara Reck-Peterson @samreckpeterson.bsky.social @cells4planethealth.bsky.social @embo.org share a call to action to apply the lens of #cellbio to climate challenges.
Cell biology meets climate resilience – a call to action
The molecular and cellular biology community has always been driven by a fascination with mechanisms – how proteins interact, how organelles communicate and how cells respond to stimuli. Yet one of th...
journals.biologists.com
March 25, 2025 at 9:22 AM
Mónica Bettencourt-Dias @monicabettencourt.bsky.social, Amy Gladfelter @gladfelterlab.bsky.social, Gautam Dey @gautamdey.bsky.social Samara Reck-Peterson @samreckpeterson.bsky.social @cells4planethealth.bsky.social @embo.org share a call to action to apply the lens of #cellbio to climate challenges.
Excited to share our first story on nuclear paraspeckles! Led by @sneadlab.bsky.social, this is the culmination of a ~4 year effort in collab. with @shrinivaslab.bsky.social. Can’t wait to see more paraspeckle stories from the future Snead Lab at Northwestern 🫧 www.biorxiv.org/content/10.1...
Immiscible proteins compete for RNA binding to order condensate layers
Biomolecular condensates mediate diverse and essential cellular functions by compartmentalizing biochemical pathways. Many condensates have internal subdomains with distinct compositional identities. ...
www.biorxiv.org
March 19, 2025 at 7:09 PM
Excited to share our first story on nuclear paraspeckles! Led by @sneadlab.bsky.social, this is the culmination of a ~4 year effort in collab. with @shrinivaslab.bsky.social. Can’t wait to see more paraspeckle stories from the future Snead Lab at Northwestern 🫧 www.biorxiv.org/content/10.1...
The mysteries of septins continue to unfold in this study examining mechanisms of septin polymerization and assembly! www.biorxiv.org/content/10.1...
Cooperativity in septin polymerization is tunable by ionic strength and membrane adsorption
Cells employ cytoskeletal polymers to move, divide, and pass information inside and outside of the cell. Previous work on eukaryotic cytoskeletal elements such as actin, microtubules, and intermediate...
www.biorxiv.org
February 18, 2025 at 10:46 PM
The mysteries of septins continue to unfold in this study examining mechanisms of septin polymerization and assembly! www.biorxiv.org/content/10.1...
We are excited to share our next installment of insights into how septins sense micron-scale curvature via detecting lipid packing! www.biorxiv.org/content/10.1...
Lipid packing and local geometry influence septin curvature sensing
Septins assemble into scaffolds that direct cell growth and morphology that are often localized to the plasma membrane. While septins preferentially bind convex membranes via amphipathic helices, thei...
www.biorxiv.org
February 18, 2025 at 10:23 PM
We are excited to share our next installment of insights into how septins sense micron-scale curvature via detecting lipid packing! www.biorxiv.org/content/10.1...
Change your life! Physiology course application deadline is extended to February 3rd! Apply now for a summer of discovery at MBL!
🗣️ Physiologists, rejoice! Thought you missed the deadline for the 2025 Physiology course at MBL? Don't toss out that application draft—you can now apply through February 3.
Read more: bit.ly/3BZSj9c
#ScienceStartsHere
Read more: bit.ly/3BZSj9c
#ScienceStartsHere
January 29, 2025 at 2:27 PM
Change your life! Physiology course application deadline is extended to February 3rd! Apply now for a summer of discovery at MBL!
The deadline for @cells4planethealth.bsky.social has been extended to February 1st- register now! meetings.embo.org/event/25-cli...
Integrating cell and planetary scales to address climate resilience
The climate crisis is a multiscale problem that requires transdisciplinary expertise for understanding and engineering climate resilience. Cells are the first responders of the biosphere and yet cell…
meetings.embo.org
January 19, 2025 at 8:20 PM
The deadline for @cells4planethealth.bsky.social has been extended to February 1st- register now! meetings.embo.org/event/25-cli...
The deadline to apply for the MBL Physiology course is fast approaching, January 27th! Consider applying to this amazing, life-changing research discovery experience in Woods Hole! www.mbl.edu/education/ad...
Physiology: Modern Cell Biology Using Microscopic, Biochemical and Computational Approaches | Marine Biological Laboratory
This course is at the forefront of new tools — molecular, computational, biophysical — as it prepares students to tackle emerging biological questions.
www.mbl.edu
January 19, 2025 at 8:17 PM
The deadline to apply for the MBL Physiology course is fast approaching, January 27th! Consider applying to this amazing, life-changing research discovery experience in Woods Hole! www.mbl.edu/education/ad...