🇸🇬🇨🇦🇦🇺
#IDSky #MedSky
#IDSky #MedSky
Join our statistical seminars supported by @advance-id.bsky.social & @who.int
Explore clinical trial theory & real-life examples with global experts. Master the numbers in the mission against disease here: ad-id.co/stats
Join our statistical seminars supported by @advance-id.bsky.social & @who.int
Explore clinical trial theory & real-life examples with global experts. Master the numbers in the mission against disease here: ad-id.co/stats
So how did 6 large language models compare to humans when extracting data from #RCTs for a systematic review?
Not very well: overall #LLM concordance was 0.58-0.75.
#IDSky
@steventong.bsky.social
@seanong.bsky.social
cmi-comms.org/article/S295...
So how did 6 large language models compare to humans when extracting data from #RCTs for a systematic review?
Not very well: overall #LLM concordance was 0.58-0.75.
#IDSky
@steventong.bsky.social
@seanong.bsky.social
cmi-comms.org/article/S295...
✅ Just Accepted
🔗 https://bit.ly/4vTJLHo
✅ Just Accepted
🔗 https://bit.ly/4vTJLHo
Larger samples and systematic AMR assessment among participants will be likely required to prove benefit
academic.oup.com/ofid/article... #IDSky #AMSsky
Awesome work by @seanong.bsky.social et al
Larger samples and systematic AMR assessment among participants will be likely required to prove benefit
academic.oup.com/ofid/article... #IDSky #AMSsky
Awesome work by @seanong.bsky.social et al
We reviewed clinical studies & conducted PTA sims to elucidate this #IDSky @absteward.bsky.social
accpjournals.onlinelibrary.wiley.com/doi/10.1002/...
We reviewed clinical studies & conducted PTA sims to elucidate this #IDSky @absteward.bsky.social
accpjournals.onlinelibrary.wiley.com/doi/10.1002/...
COBRA Trial – One day is enough
Dutch RCT: 1 day of antibiotics after ERCP drainage for cholangitis was non‑inferior to 4–7 days.
Bottom line: Antibiotic durations can safely be much shorter once source control is achieved.
#IDSky
clarityinitiative.org/escmid-2026-...
COBRA Trial – One day is enough
Dutch RCT: 1 day of antibiotics after ERCP drainage for cholangitis was non‑inferior to 4–7 days.
Bottom line: Antibiotic durations can safely be much shorter once source control is achieved.
#IDSky
clarityinitiative.org/escmid-2026-...
www.clinicalmicrobiologyandinfection.org/article/S119...
www.clinicalmicrobiologyandinfection.org/article/S119...
@gurujosh.bsky.social asked CLARITY faculty: @angelahuttner.bsky.social @erinmccreary.bsky.social @marcbonten.bsky.social @seanong.bsky.social @ashabowen.bsky.social and others (not on BlueSky).
#IDSky
clarityinitiative.org/escmid-2026-...
Any that we missed?
@gurujosh.bsky.social asked CLARITY faculty: @angelahuttner.bsky.social @erinmccreary.bsky.social @marcbonten.bsky.social @seanong.bsky.social @ashabowen.bsky.social and others (not on BlueSky).
#IDSky
clarityinitiative.org/escmid-2026-...
Any that we missed?
Groups: none, early (only empiric B-lactam), late (only after trial enrolment), throughout (empiric and after enrolment).
#IDSky
www.clinicalmicrobiologyandinfection.org/article/S119...
Groups: none, early (only empiric B-lactam), late (only after trial enrolment), throughout (empiric and after enrolment).
#IDSky
www.clinicalmicrobiologyandinfection.org/article/S119...
1-day of antibiotic treatment after adequate endoscopic biliary drainage is non-inferior to 4-7 days in adults with acute cholangitis.
💡 Shorter is better+source control
Practice-changing? #ESCMIDGlobal2026 #idsky
1-day of antibiotic treatment after adequate endoscopic biliary drainage is non-inferior to 4-7 days in adults with acute cholangitis.
💡 Shorter is better+source control
Practice-changing? #ESCMIDGlobal2026 #idsky
My main worry is lower ranked components dominating
Sarah Walker discussed this issue in her excellent Bradford Hill lecture (recording in link)
My main worry is lower ranked components dominating
Sarah Walker discussed this issue in her excellent Bradford Hill lecture (recording in link)
This time looking at the GAMECHANGER trial:
clarityinitiative.org/commentaries...
@erinmccreary.bsky.social with Ahmad Mourad
@gurujosh.bsky.social
#IDSky
This time looking at the GAMECHANGER trial:
clarityinitiative.org/commentaries...
@erinmccreary.bsky.social with Ahmad Mourad
@gurujosh.bsky.social
#IDSky
#IDSky #SNAP_trial
www.sciencedirect.com/science/arti...
#IDSky #SNAP_trial
www.sciencedirect.com/science/arti...
www.clinicalmicrobiologyandinfection.org/article/S119...
We use the BALANCE and CAMERA2 trials as case studies to illustrate the use of the different methods available for analysis of hierarchical composite endpoints.
#IDSky @steventong.bsky.social
www.clinicalmicrobiologyandinfection.org/article/S119...
We use the BALANCE and CAMERA2 trials as case studies to illustrate the use of the different methods available for analysis of hierarchical composite endpoints.
#IDSky @steventong.bsky.social
https://ow.ly/HZao50XwVYg
#IDSky #clinmicro
https://ow.ly/HZao50XwVYg
#IDSky #clinmicro
unimelb.zoom.us/j/8944229688...
@thedohertyinst.bsky.social
unimelb.zoom.us/j/8944229688...
@thedohertyinst.bsky.social
Accounting for non-adherence to assigned antibiotic treatment duration for bloodstream infection (BALANCE): a post-hoc analysis of a randomised clinical trial
www.thelancet.com/journals/lan...
Accounting for non-adherence to assigned antibiotic treatment duration for bloodstream infection (BALANCE): a post-hoc analysis of a randomised clinical trial
www.thelancet.com/journals/lan...
authors.elsevier.com/a/1m5He5E-Uo...
@steventong.bsky.social #IDSky
authors.elsevier.com/a/1m5He5E-Uo...
@steventong.bsky.social #IDSky
More info here: forms.gle/H9TXEMkwM1cb...
Please spread far and wide!
@steventong.bsky.social #IDSky
More info here: forms.gle/H9TXEMkwM1cb...
Please spread far and wide!
@steventong.bsky.social #IDSky
Joining the X-odus: Contrasting perspectives on whether infection specialists should leave X (formerly Twitter)
That I'm sharing it here belies where I stand on the issue
www.cmi-comms.org/article/S295... #IDSky
#IDSky #Clinmicro
#IDSky #Clinmicro
doi.org/10.1016/j.cm...
@steventong.bsky.social #IDSky
doi.org/10.1016/j.cm...
@steventong.bsky.social #IDSky
Compared to similar non-trial population w/ MRSA bacteremia:
-No difference in 🪦, BUT
-non-trial had less following of quality metrics (see ⬇️)
#IDSky
jamanetwork.com/journals/jam...
Compared to similar non-trial population w/ MRSA bacteremia:
-No difference in 🪦, BUT
-non-trial had less following of quality metrics (see ⬇️)
#IDSky
jamanetwork.com/journals/jam...