Joe Sorg
@thejoesorg.bsky.social
Professor at Texas A&M Biology. Interested in C. difficile spores and physiology
Reposted by Joe Sorg
Is asymptomatic colonization with Clostridioides difficile (C. diff) early in life truly “silent?” In my first publication from the Zackular Lab, out today in @science.org, I teamed up with my amazing lab-mate, Alexa Semon, to find the answer.
Link here: www.science.org/doi/10.1126/...
Link here: www.science.org/doi/10.1126/...
Early-life colonization with Clostridioides difficile remodels the developing gut
Clostridioides difficile causes severe disease in adults but commonly colonizes infants asymptomatically. The consequences of early-life colonization on host development remain unknown. In a neonatal ...
www.science.org
September 3, 2026 at 7:51 PM
Is asymptomatic colonization with Clostridioides difficile (C. diff) early in life truly “silent?” In my first publication from the Zackular Lab, out today in @science.org, I teamed up with my amazing lab-mate, Alexa Semon, to find the answer.
Link here: www.science.org/doi/10.1126/...
Link here: www.science.org/doi/10.1126/...
Reposted by Joe Sorg
Since its first isolation in 1935, several thousand Clostridioides difficile isolates have been collected & analyzed. In #ClinMicroRev: an overview of the current C. difficile population structure, including a summary of the 5 main clades. Read now: asm.social/2TC
April 14, 2026 at 6:09 PM
Since its first isolation in 1935, several thousand Clostridioides difficile isolates have been collected & analyzed. In #ClinMicroRev: an overview of the current C. difficile population structure, including a summary of the 5 main clades. Read now: asm.social/2TC
Reposted by Joe Sorg
Vedanta Biosciences Announces the Phase 3 RESTORATiVE303 Study of VE303 for the Prevention of Recurrent C. difficile Infection Will Continue as Planned Following Protocol-Specified Interim Analysis
April 4, 2026 at 1:49 PM
Vedanta Biosciences Announces the Phase 3 RESTORATiVE303 Study of VE303 for the Prevention of Recurrent C. difficile Infection Will Continue as Planned Following Protocol-Specified Interim Analysis
Reposted by Joe Sorg
Join us in beautiful Madison WI! In addition to the postdoc call I previously announced, I am seeking applicants for a Scientist position. IMO this position is best suited for someone who successfully completed their postdoctoral training, see here for more details: jobs.wisc.edu/jobs/scienti...
Scientist I – C. difficile and Gut Microbiome - Madison, Wisconsin, United States
Current Employees: If you are currently employed at any of the Universities of Wisconsin, log in to Workday to apply through the internal application process.Job Category:Academic StaffEmployment Type...
jobs.wisc.edu
March 5, 2026 at 3:27 PM
Join us in beautiful Madison WI! In addition to the postdoc call I previously announced, I am seeking applicants for a Scientist position. IMO this position is best suited for someone who successfully completed their postdoctoral training, see here for more details: jobs.wisc.edu/jobs/scienti...
Reposted by Joe Sorg
New paper from us.
If you're interested in genetic manipulation of Clostridia, we have a few new tools for you! 36 new plasmids - all available from @addgene.bsky.social
www.microbiologyresearch.org/content/jour...
#microsky
If you're interested in genetic manipulation of Clostridia, we have a few new tools for you! 36 new plasmids - all available from @addgene.bsky.social
www.microbiologyresearch.org/content/jour...
#microsky
A set of genetic tools for use in Clostridioides difficile and related species
The Clostridia are a phylogenetically diverse group of anaerobic, spore-forming bacteria that include species of medical, veterinary and industrial importance. The last two decades have seen major adv...
www.microbiologyresearch.org
February 19, 2026 at 10:55 PM
New paper from us.
If you're interested in genetic manipulation of Clostridia, we have a few new tools for you! 36 new plasmids - all available from @addgene.bsky.social
www.microbiologyresearch.org/content/jour...
#microsky
If you're interested in genetic manipulation of Clostridia, we have a few new tools for you! 36 new plasmids - all available from @addgene.bsky.social
www.microbiologyresearch.org/content/jour...
#microsky
Reposted by Joe Sorg
New in JB: Weiss, Tamayo et al. describe a very cool microbial interaction wherein Enterococcus faecalis, an opportunist found in the inflamed gut, impacts phase-variation noted by chaining & rough colony morphology of C. diff.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
February 13, 2026 at 4:31 PM
Reposted by Joe Sorg
The CspC:CspA heterodimer transduces germinant and co-germinant signals during Clostridioides difficile spore germination dx.plos.org/10.1371/jour...
The CspC:CspA heterodimer transduces germinant and co-germinant signals during Clostridioides difficile spore germination
Unlike other bacteria, C. difficile must detect both a germinant signal and a co-germinant signal to trigger spore germination, but how these cues are sensed is unknown. This study finds that the CspC...
dx.plos.org
February 13, 2026 at 2:05 PM
The CspC:CspA heterodimer transduces germinant and co-germinant signals during Clostridioides difficile spore germination dx.plos.org/10.1371/jour...
Reposted by Joe Sorg
You mean my hours spent as a chronically online teenager are finally going to benefit me 20 years later!?!?
January 16, 2026 at 11:39 AM
You mean my hours spent as a chronically online teenager are finally going to benefit me 20 years later!?!?
Reposted by Joe Sorg
I am on version 10 of my NIH Common Form cv because I spent the last 2 hours doing HTML formatting on the text and finding things I missed formatting.
My heart goes out to all the reviewers who will be reading biosketches next round that are a sea of plaintext with no white space.
My heart goes out to all the reviewers who will be reading biosketches next round that are a sea of plaintext with no white space.
January 6, 2026 at 12:43 AM
I am on version 10 of my NIH Common Form cv because I spent the last 2 hours doing HTML formatting on the text and finding things I missed formatting.
My heart goes out to all the reviewers who will be reading biosketches next round that are a sea of plaintext with no white space.
My heart goes out to all the reviewers who will be reading biosketches next round that are a sea of plaintext with no white space.
Reposted by Joe Sorg
No ads. No paywalls. No sponsors shaping the message.
MicrobeTV exists to make science education freely available, even when that’s the harder path.
If our programs have informed or helped you this year, we hope you’ll consider making a contribution.
@jrrmicro.bsky.social
MicrobeTV exists to make science education freely available, even when that’s the harder path.
If our programs have informed or helped you this year, we hope you’ll consider making a contribution.
@jrrmicro.bsky.social
December 30, 2025 at 6:10 PM
No ads. No paywalls. No sponsors shaping the message.
MicrobeTV exists to make science education freely available, even when that’s the harder path.
If our programs have informed or helped you this year, we hope you’ll consider making a contribution.
@jrrmicro.bsky.social
MicrobeTV exists to make science education freely available, even when that’s the harder path.
If our programs have informed or helped you this year, we hope you’ll consider making a contribution.
@jrrmicro.bsky.social
Reposted by Joe Sorg
Friday we lost a brilliant mind, colleague, and friend to her battle with pancreatic cancer. Those who knew her will remember Helene Andrews-Polymenis for her warmth, generosity and leadership. She will be missed by many. RIP
December 23, 2025 at 8:36 AM
Friday we lost a brilliant mind, colleague, and friend to her battle with pancreatic cancer. Those who knew her will remember Helene Andrews-Polymenis for her warmth, generosity and leadership. She will be missed by many. RIP
Reposted by Joe Sorg
Helene was so giving to others about her battle, and went through to make it into maybe the top 1% of survivors of pancreatic cancer, before succumbing Dec 19, 2025 all while losing her father to it. She supported @letswinpc.org and the family asks for you to consider supporting them as well.💔
Pancreatic cancer survivor Helene Andrews-Polymenis and Dr. John Chabot discuss strategies for preparing for a Whipple procedure.
Preparing for a Whipple Procedure: A Roadmap for Patients and Caregivers
Pancreatic cancer survivor Helene Andrews-Polymenis and Dr. John Chabot discuss strategies for preparing for a Whipple procedure.
buff.ly
December 22, 2025 at 8:28 PM
Helene was so giving to others about her battle, and went through to make it into maybe the top 1% of survivors of pancreatic cancer, before succumbing Dec 19, 2025 all while losing her father to it. She supported @letswinpc.org and the family asks for you to consider supporting them as well.💔
Can we, as a community, agree to stop submitting papers before a Winter / Holiday break? On the reviewer side, it’s gonna be a while. On the editor side, it’s impossible to find reviewers. That paper can wait until January. 😇
December 23, 2025 at 12:40 PM
Can we, as a community, agree to stop submitting papers before a Winter / Holiday break? On the reviewer side, it’s gonna be a while. On the editor side, it’s impossible to find reviewers. That paper can wait until January. 😇
Reposted by Joe Sorg
🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
Faculty Professor Associate - Full-Time | Vaughn Cooper
We are recruiting Faculty microbiologists in three (3) different, complementary, and collaborative areas at the University of Pittsburgh associated with the School of Medicine.
1) Fundamental researc...
www.linkedin.com
September 23, 2025 at 10:31 PM
🚨 Microbiologists! We are recruiting Assistant / Associate Professors in 3 collaborative areas of our U. Pittsburgh School of Medicine.
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
1) MMG (my dept): fundamental research in med micro
2) Peds ID / I4Kids institute
3) Center for Vaccine Research
🔗 to all 3 w/info: www.linkedin.com/posts/vaughn...
Reposted by Joe Sorg
A targeted cell lysis mechanism facilitates toxin release in Clostridioides difficile www.biorxiv.org/content/10.1...
A targeted cell lysis mechanism facilitates toxin release in Clostridioides difficile
Clostridioides difficile infection is associated with the production of two large toxins, TcdA and TcdB. The toxins are encoded in a pathogenicity locus along with a phage-like holin protein, TcdE, th...
www.biorxiv.org
September 23, 2025 at 7:56 AM
A targeted cell lysis mechanism facilitates toxin release in Clostridioides difficile www.biorxiv.org/content/10.1...
Reposted by Joe Sorg
We're hiring! 5 tenure track assistant professors. 2 #microbiology, 2 #Evolution, 1 #biologicalclocks
jobs.sciencecareers.org/job/675062/f...
jobs.sciencecareers.org/job/675062/f...
Five Tenure-Track Assistant Professor Positions in Microbiology, Evolution, and Biological Clocks - College Station, Texas job with Department of Biology - TAMU | 675062
Texas A&M University (TAMU) invites applications for five full-time, tenure-track Assistant Professor positions
jobs.sciencecareers.org
September 12, 2025 at 6:11 PM
We're hiring! 5 tenure track assistant professors. 2 #microbiology, 2 #Evolution, 1 #biologicalclocks
jobs.sciencecareers.org/job/675062/f...
jobs.sciencecareers.org/job/675062/f...
Reposted by Joe Sorg
We are hiring! Please share the news.
Tenure Track Assistant Professor in Bacterial Pathogenesis
See link below for details.
We are a vibrantly growing department with friendly colleagues and supportive environment. Bonus: year-round sunshine in Tampa, FL 🌤🌴
Job Ad: tinyurl.com/USF-Microbio...
Tenure Track Assistant Professor in Bacterial Pathogenesis
See link below for details.
We are a vibrantly growing department with friendly colleagues and supportive environment. Bonus: year-round sunshine in Tampa, FL 🌤🌴
Job Ad: tinyurl.com/USF-Microbio...
Assistant Professor - Molecular Biosciences
Department Name / Number: Molecular Biosciences / 0-1210-000 College: College of Arts and Sciences Hiring Salary: Negotiable Appointment Start Date: August 7, 2026 The Department of Molecular Bioscien...
tinyurl.com
September 12, 2025 at 1:53 PM
We are hiring! Please share the news.
Tenure Track Assistant Professor in Bacterial Pathogenesis
See link below for details.
We are a vibrantly growing department with friendly colleagues and supportive environment. Bonus: year-round sunshine in Tampa, FL 🌤🌴
Job Ad: tinyurl.com/USF-Microbio...
Tenure Track Assistant Professor in Bacterial Pathogenesis
See link below for details.
We are a vibrantly growing department with friendly colleagues and supportive environment. Bonus: year-round sunshine in Tampa, FL 🌤🌴
Job Ad: tinyurl.com/USF-Microbio...
We're hiring! 5 tenure track assistant professors. 2 #microbiology, 2 #Evolution, 1 #biologicalclocks
jobs.sciencecareers.org/job/675062/f...
jobs.sciencecareers.org/job/675062/f...
Five Tenure-Track Assistant Professor Positions in Microbiology, Evolution, and Biological Clocks - College Station, Texas job with Department of Biology - TAMU | 675062
Texas A&M University (TAMU) invites applications for five full-time, tenure-track Assistant Professor positions
jobs.sciencecareers.org
September 12, 2025 at 6:11 PM
We're hiring! 5 tenure track assistant professors. 2 #microbiology, 2 #Evolution, 1 #biologicalclocks
jobs.sciencecareers.org/job/675062/f...
jobs.sciencecareers.org/job/675062/f...
Reposted by Joe Sorg
The Tufts IRACDA Program is now accepting applications. The deadline for positions beginning in late fall/early winter 2025–2026 is October 15, 2025. For details, please visit gsbs.tufts.edu/academics/tu...
I am also happy to discuss potential fellowship projects in my lab.
I am also happy to discuss potential fellowship projects in my lab.
Tufts IRACDA Program | Graduate School of Biomedical Sciences
gsbs.tufts.edu
September 12, 2025 at 12:42 PM
The Tufts IRACDA Program is now accepting applications. The deadline for positions beginning in late fall/early winter 2025–2026 is October 15, 2025. For details, please visit gsbs.tufts.edu/academics/tu...
I am also happy to discuss potential fellowship projects in my lab.
I am also happy to discuss potential fellowship projects in my lab.
Reposted by Joe Sorg
Meet Mighty Mitochondria, TAMU Biology's newest department ambassador! Mighty had a great time today meeting students and getting ready for classes on Monday! WHOOP!
August 22, 2025 at 7:14 PM
Meet Mighty Mitochondria, TAMU Biology's newest department ambassador! Mighty had a great time today meeting students and getting ready for classes on Monday! WHOOP!
Reposted by Joe Sorg
Our Pitt Microbiology and Molecular Genetics department in the School of Medicine is recruiting..
Microbiologists! 🧫🦠🔬🧪
Please apply to join our faculty and enjoy these views 👀 while doing great science
cfopitt.taleo.net/careersectio...
Microbiologists! 🧫🦠🔬🧪
Please apply to join our faculty and enjoy these views 👀 while doing great science
cfopitt.taleo.net/careersectio...
August 21, 2025 at 3:19 PM
Our Pitt Microbiology and Molecular Genetics department in the School of Medicine is recruiting..
Microbiologists! 🧫🦠🔬🧪
Please apply to join our faculty and enjoy these views 👀 while doing great science
cfopitt.taleo.net/careersectio...
Microbiologists! 🧫🦠🔬🧪
Please apply to join our faculty and enjoy these views 👀 while doing great science
cfopitt.taleo.net/careersectio...
Reposted by Joe Sorg
Dr. James Smith’s research in TAMU Biology is uncovering powerful new antimicrobial agents to treat multidrug-resistant infections. By combining discovery with clinical innovation, his work is shaping our fight against these dangerous pathogens! tx.ag/smith25
Fighting Infection, One Molecule at a Time
Antimicrobial agents do more than just fight infections—they open windows into the fundamental workings of life. Dr. James Smith has built a career defined by translating breakthrough antimicrobial di...
tx.ag
August 11, 2025 at 8:56 PM
Dr. James Smith’s research in TAMU Biology is uncovering powerful new antimicrobial agents to treat multidrug-resistant infections. By combining discovery with clinical innovation, his work is shaping our fight against these dangerous pathogens! tx.ag/smith25
Reposted by Joe Sorg
This fall, Texas A&M Biology welcomes over 750 new biology students to campus! We’re excited to kick off a year of discovery, learning, & scientific growth with our amazing undergraduate & graduate Aggies. Here’s to a great semester, welcome Aggies! tx.ag/welcome25
Department of Biology Welcomes 750+ New Students for Fall 2025
The Department of Biology at Texas A&M University is thrilled to welcome more than 750 new undergraduate and graduate students as classes begin next week for the fall semester. With excitement and ant...
tx.ag
August 18, 2025 at 6:22 PM
This fall, Texas A&M Biology welcomes over 750 new biology students to campus! We’re excited to kick off a year of discovery, learning, & scientific growth with our amazing undergraduate & graduate Aggies. Here’s to a great semester, welcome Aggies! tx.ag/welcome25
Reposted by Joe Sorg
August 16, 2025 at 6:48 PM
Reposted by Joe Sorg
Can viruses help fight antibiotic-resistant bacteria? Dr. Jolene Ramsey in TAMU Biology is harnessing bacteriophages, bacterial predators, to develop targeted therapies against dangerous infections. Discover how phage research changes the future! tx.ag/ramsey25
Fighting Superbugs with Viruses: Dr. Jolene Ramsey’s Research Explores Bacteriophages as a New Frontier
As antibiotic resistance threatens to undermine decades of medical progress, Dr. Jolene Ramsey is using one of nature’s oldest and most precise bacterial predators for solutions: bacteriophages, or si...
tx.ag
August 14, 2025 at 4:41 PM
Can viruses help fight antibiotic-resistant bacteria? Dr. Jolene Ramsey in TAMU Biology is harnessing bacteriophages, bacterial predators, to develop targeted therapies against dangerous infections. Discover how phage research changes the future! tx.ag/ramsey25