Lana
@lanabuzuk.bsky.social
PhD Student in the Hellerschmied Lab
Golgi Stress Responses | Ubiquitination | Protein Quality Control
Golgi Stress Responses | Ubiquitination | Protein Quality Control
Reposted by Lana
Are you ready to submit your application?
Deadline extended: 4 October, 2026
For more information and to apply: www.imprs-lm.mpg.de/join/apply/
#IMPRS-LM #PhDpositions #FullyFunded #LifeScience
Deadline extended: 4 October, 2026
For more information and to apply: www.imprs-lm.mpg.de/join/apply/
#IMPRS-LM #PhDpositions #FullyFunded #LifeScience
September 30, 2026 at 8:35 AM
Are you ready to submit your application?
Deadline extended: 4 October, 2026
For more information and to apply: www.imprs-lm.mpg.de/join/apply/
#IMPRS-LM #PhDpositions #FullyFunded #LifeScience
Deadline extended: 4 October, 2026
For more information and to apply: www.imprs-lm.mpg.de/join/apply/
#IMPRS-LM #PhDpositions #FullyFunded #LifeScience
Reposted by Lana
@lsajournal.org
doi.org/10.26508/lsa...
Paper out: Cool dTAG approach by Dani and Maike for acute perturbation of the #VCP/p97 system nailing down a function during DNA #replication. #ubiquitin. @crc1430.bsky.social @unidue-zmb.bsky.social Thanks to our collaborators, the Beli and Boos labs.
doi.org/10.26508/lsa...
Paper out: Cool dTAG approach by Dani and Maike for acute perturbation of the #VCP/p97 system nailing down a function during DNA #replication. #ubiquitin. @crc1430.bsky.social @unidue-zmb.bsky.social Thanks to our collaborators, the Beli and Boos labs.
Induced degradation of Ufd1 reveals regulation of cohesin by the VCP/p97Ufd1-Npl4 complex
The AAA ATPase VCP/p97 has emerged as a critical regulator of ubiquitin and chromatin-associated processes but progress in understanding has been hampered by the complexity of p97 functions and the va...
doi.org
September 4, 2026 at 9:08 AM
@lsajournal.org
doi.org/10.26508/lsa...
Paper out: Cool dTAG approach by Dani and Maike for acute perturbation of the #VCP/p97 system nailing down a function during DNA #replication. #ubiquitin. @crc1430.bsky.social @unidue-zmb.bsky.social Thanks to our collaborators, the Beli and Boos labs.
doi.org/10.26508/lsa...
Paper out: Cool dTAG approach by Dani and Maike for acute perturbation of the #VCP/p97 system nailing down a function during DNA #replication. #ubiquitin. @crc1430.bsky.social @unidue-zmb.bsky.social Thanks to our collaborators, the Beli and Boos labs.
Reposted by Lana
Great PhD Retreat at Unperfekthaus Essen! Connected across projects, presented science in talks & Chalk Talks and discussed career paths in a panel with both industry & academia backgrounds. Thanks for inspiring discussions, exchange and new connections! 🧪 #CRC1430 #Networking @leokiss.bsky.social
July 6, 2026 at 10:22 AM
Great PhD Retreat at Unperfekthaus Essen! Connected across projects, presented science in talks & Chalk Talks and discussed career paths in a panel with both industry & academia backgrounds. Thanks for inspiring discussions, exchange and new connections! 🧪 #CRC1430 #Networking @leokiss.bsky.social
Reposted by Lana
Great opportunity for the #ubiquitin community and fantastic speaker line-up!
#ZMB member @hemmo-lab.bsky.social included, alongside many other outstanding colleagues.
#EMBOubiquitin #EMBOevents 🧪
#ZMB member @hemmo-lab.bsky.social included, alongside many other outstanding colleagues.
#EMBOubiquitin #EMBOevents 🧪
Don't miss out! Registration is still open for the EMBO Workshop "#Ubiquitin and ubiquitin-like proteins in health and disease" in Monopoli, Italy, 28 Sep–2 Oct 2026.
Registration by 31 May
Abstract submission by 15 Jun
https://meetings.embo.org/event/26-ubiquitin
#EMBOubiquitin #EMBOevents 🧪
Registration by 31 May
Abstract submission by 15 Jun
https://meetings.embo.org/event/26-ubiquitin
#EMBOubiquitin #EMBOevents 🧪
May 20, 2026 at 10:11 AM
Great opportunity for the #ubiquitin community and fantastic speaker line-up!
#ZMB member @hemmo-lab.bsky.social included, alongside many other outstanding colleagues.
#EMBOubiquitin #EMBOevents 🧪
#ZMB member @hemmo-lab.bsky.social included, alongside many other outstanding colleagues.
#EMBOubiquitin #EMBOevents 🧪
Reposted by Lana
Cdc48/p97 nibbling on #ubiquitin! Cool single molecule analysis study by the Tans group (with us) out now.
rdcu.be/firGK
rdcu.be/firGK
May 13, 2026 at 6:41 AM
Cdc48/p97 nibbling on #ubiquitin! Cool single molecule analysis study by the Tans group (with us) out now.
rdcu.be/firGK
rdcu.be/firGK
Reposted by Lana
Many thanks to @lanabuzuk.bsky.social from the @hellerschmiedlab.bsky.social for taking over this account over the past few days and sharing updates from the #17GPS @unidue.bsky.social. Really appreciate you keeping everyone in the loop!
March 9, 2026 at 10:53 AM
Many thanks to @lanabuzuk.bsky.social from the @hellerschmiedlab.bsky.social for taking over this account over the past few days and sharing updates from the #17GPS @unidue.bsky.social. Really appreciate you keeping everyone in the loop!
Had a great time at the 17th German #Peptide Symposium! Lots of interesting science and engaging conversations 🤩
I was happy to share my own work, and even won a poster prize! 🎉
👏🏻 A special thanks goes to all of the organisers that made the symposium a truly engaging event!
#17GPS
I was happy to share my own work, and even won a poster prize! 🎉
👏🏻 A special thanks goes to all of the organisers that made the symposium a truly engaging event!
#17GPS
March 7, 2026 at 10:29 AM
Reposted by Lana
VCP/p97’s accessory adapters (FAF1, FAF2, UBXN7) boost unfolding and subsequent proteasomal degradation. #ubiquitin. Our paper is out now:
Science Advances www.science.org/doi/10.1126/...
Science Advances www.science.org/doi/10.1126/...
The accessory adapters FAF1, FAF2, and UBXN7 accelerate proteasomal degradation by increasing prior p97-mediated substrate unfolding
A group of accessory adapters positions the p97 adapter Ufd1 to boost substrate unfolding and subsequent proteasomal degradation.
www.science.org
March 6, 2026 at 7:11 PM
VCP/p97’s accessory adapters (FAF1, FAF2, UBXN7) boost unfolding and subsequent proteasomal degradation. #ubiquitin. Our paper is out now:
Science Advances www.science.org/doi/10.1126/...
Science Advances www.science.org/doi/10.1126/...
Reposted by Lana
Reposted by Lana
I am incredibly excited to share that I will start my independent lab at the @unidue-zmb.bsky.social at the @unidue.bsky.social as Junior Professor of Cellular Biochemistry. Research in my lab has the goal to decipher the ubiquitin code!
There are multiple open positions!
(1/3)
There are multiple open positions!
(1/3)
March 5, 2026 at 11:00 AM
I am incredibly excited to share that I will start my independent lab at the @unidue-zmb.bsky.social at the @unidue.bsky.social as Junior Professor of Cellular Biochemistry. Research in my lab has the goal to decipher the ubiquitin code!
There are multiple open positions!
(1/3)
There are multiple open positions!
(1/3)
Reposted by Lana
Are you passionate about interdisciplinary research and eager to contribute to groundbreaking discoveries in the areas of #biochemistry, #structuralbiology, #biophysics, #cellbiology, #chemicalbiology and #syntheticbiology? Apply NOW for a #fullyfunded #PhDpositions @IMPRS-LM.
Deadline: April 6
Deadline: April 6
March 5, 2026 at 9:59 AM
Are you passionate about interdisciplinary research and eager to contribute to groundbreaking discoveries in the areas of #biochemistry, #structuralbiology, #biophysics, #cellbiology, #chemicalbiology and #syntheticbiology? Apply NOW for a #fullyfunded #PhDpositions @IMPRS-LM.
Deadline: April 6
Deadline: April 6
Reposted by Lana
ZMB members, @mbogyo.bsky.social will be giving the ZMB/CRC1430 talk tomorrow at 11 am. Set a reminder and don’t miss out on this fantastic talk!
March 4, 2026 at 5:58 PM
ZMB members, @mbogyo.bsky.social will be giving the ZMB/CRC1430 talk tomorrow at 11 am. Set a reminder and don’t miss out on this fantastic talk!
Reposted by Lana
Now it is time for the early career researchers to take the stage and present their research in our poster sessions! Grab a drink and a snack, and let’s talk science!
#17GPS
#17GPS
March 4, 2026 at 6:28 PM
Now it is time for the early career researchers to take the stage and present their research in our poster sessions! Grab a drink and a snack, and let’s talk science!
#17GPS
#17GPS
Reposted by Lana
📆 Today is the day! The 17th German #Peptide Symposium starts this afternoon at 4 pm in Essen @unidue.bsky.social
☕ Make sure to arrive around 3 pm for the registration and coffee
🔗 The program for the whole symposium can be found here www.uni-due.de/imperia/md/i...
#17GPS
☕ Make sure to arrive around 3 pm for the registration and coffee
🔗 The program for the whole symposium can be found here www.uni-due.de/imperia/md/i...
#17GPS
www.uni-due.de
March 4, 2026 at 9:17 AM
📆 Today is the day! The 17th German #Peptide Symposium starts this afternoon at 4 pm in Essen @unidue.bsky.social
☕ Make sure to arrive around 3 pm for the registration and coffee
🔗 The program for the whole symposium can be found here www.uni-due.de/imperia/md/i...
#17GPS
☕ Make sure to arrive around 3 pm for the registration and coffee
🔗 The program for the whole symposium can be found here www.uni-due.de/imperia/md/i...
#17GPS
👋I’m @lanabuzuk.bsky.social a PhD student from the @hellerschmiedlab.bsky.social , and I will be taking over the ZMB account for the duration of the symposium (4th – 6th March) and I will be providing live coverage of the talks and the events.
3/3
3/3
February 25, 2026 at 12:13 PM
Reposted by Lana
📆In just one week, we will be hosting the 17th German #Peptide Symposium in Essen @unidue.bsky.social!
We are excited to host an open-topic event on modern peptide chemistry with a fantastic line up of speakers.
#17GPS
1/3
We are excited to host an open-topic event on modern peptide chemistry with a fantastic line up of speakers.
#17GPS
1/3
February 25, 2026 at 12:07 PM
📆In just one week, we will be hosting the 17th German #Peptide Symposium in Essen @unidue.bsky.social!
We are excited to host an open-topic event on modern peptide chemistry with a fantastic line up of speakers.
#17GPS
1/3
We are excited to host an open-topic event on modern peptide chemistry with a fantastic line up of speakers.
#17GPS
1/3
Reposted by Lana
Very happy to share our new preprint on #Golgi #PQC Very grateful to be working at the @hellerschmiedlab.bsky.social and with all the co-authors and colleagues. Special thanks to Sofia- without her, this story wouldn't have #unfolded as it did @unidue-zmb.bsky.social @imprs-lm.bsky.social
Selective proteasomal degradation from the Golgi apparatus membrane https://www.biorxiv.org/content/10.64898/2026.02.04.703791v1
February 9, 2026 at 5:12 PM
Very happy to share our new preprint on #Golgi #PQC Very grateful to be working at the @hellerschmiedlab.bsky.social and with all the co-authors and colleagues. Special thanks to Sofia- without her, this story wouldn't have #unfolded as it did @unidue-zmb.bsky.social @imprs-lm.bsky.social
Reposted by Lana
happy to see this important work out - great paper from @joaodiamantino.bsky.social at @hellerschmiedlab.bsky.social lab identifying Golgi quality control and first EGAD components in human cells - excellent!
Very happy to share our recent preprint describing #Golgi protein quality control #PQC in mammalian cells. #proteasome #ubiquitin #ChemBio Fantastic work by @joaodiamantino.bsky.social and team! #proudPI @unidue-zmb.bsky.social @imprs-lm.bsky.social
Selective proteasomal degradation from the Golgi apparatus membrane https://www.biorxiv.org/content/10.64898/2026.02.04.703791v1
February 6, 2026 at 7:36 PM
happy to see this important work out - great paper from @joaodiamantino.bsky.social at @hellerschmiedlab.bsky.social lab identifying Golgi quality control and first EGAD components in human cells - excellent!
Reposted by Lana
Very happy to share our recent preprint describing #Golgi protein quality control #PQC in mammalian cells. #proteasome #ubiquitin #ChemBio Fantastic work by @joaodiamantino.bsky.social and team! #proudPI @unidue-zmb.bsky.social @imprs-lm.bsky.social
Selective proteasomal degradation from the Golgi apparatus membrane https://www.biorxiv.org/content/10.64898/2026.02.04.703791v1
February 6, 2026 at 8:08 AM
Very happy to share our recent preprint describing #Golgi protein quality control #PQC in mammalian cells. #proteasome #ubiquitin #ChemBio Fantastic work by @joaodiamantino.bsky.social and team! #proudPI @unidue-zmb.bsky.social @imprs-lm.bsky.social
Reposted by Lana
Selective proteasomal degradation from the Golgi apparatus membrane https://www.biorxiv.org/content/10.64898/2026.02.04.703791v1
February 5, 2026 at 4:30 PM
Selective proteasomal degradation from the Golgi apparatus membrane https://www.biorxiv.org/content/10.64898/2026.02.04.703791v1
Reposted by Lana
Very happy to see our contribution to a better understanding of Hsp70/90 #chaperones online! Congrats and a big thank you to all co-authors, collaborators and reviewers! #proteostasis @poepsel-lab.bsky.social @crc1430.bsky.social @unidue-zmb.bsky.social
New online: Conformational plasticity of a BiP–GRP94 chaperone complex
Conformational plasticity of a BiP–GRP94 chaperone complex
Nature Structural & Molecular Biology, Published online: 14 July 2025; doi:10.1038/s41594-025-01619-0BiP–glucose-regulated protein 94 chaperones are critical to the proper folding of secretory and transmembrane proteins. Brenner et al. provide biochemical and structural insight into a conserved mechanism of chaperone cooperation underlying this quality control process.
go.nature.com
July 15, 2025 at 6:06 AM
Very happy to see our contribution to a better understanding of Hsp70/90 #chaperones online! Congrats and a big thank you to all co-authors, collaborators and reviewers! #proteostasis @poepsel-lab.bsky.social @crc1430.bsky.social @unidue-zmb.bsky.social