When you ask an AgnoTAC what protein it degraded:
April 2, 2025 at 2:03 AM
When you ask an AgnoTAC what protein it degraded:
Happy to share a new preprint from our group in collaboration with AbbVie led by graduate student @inesforrest.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Proteome-Wide Discovery of Degradable Proteins Using Bifunctional Molecules
Targeted protein degradation (TPD) is an emergent therapeutic strategy with the potential to circumvent challenges associated with targets unamenable to conventional pharmacological inhibition. Among ...
www.biorxiv.org
March 23, 2025 at 1:07 PM