November 13, 2024 at 12:16 PM
Let's unleash the axonal growth cones for this #Fluorescencefriday ! #neuroscience #Liveimaging #microscopy #Axonguidance
November 15, 2024 at 7:19 AM
Let's unleash the axonal growth cones for this #Fluorescencefriday ! #neuroscience #Liveimaging #microscopy #Axonguidance
New on bioRxiv! 🧠🧬
Our work uncovers how modularity in the DCC-ECD shapes axon guidance and neuronal migration.Using mouse lines with mutations in Netrin-1 and Draxin binding sites, we show how distinct DCC modules drive precise circuit assembly
#Neuroscience #AxonGuidance #DCC #Netrin1 #Draxin
Our work uncovers how modularity in the DCC-ECD shapes axon guidance and neuronal migration.Using mouse lines with mutations in Netrin-1 and Draxin binding sites, we show how distinct DCC modules drive precise circuit assembly
#Neuroscience #AxonGuidance #DCC #Netrin1 #Draxin
Modularity in the DCC extracellular domain elicits distinct effects on axon guidance https://www.biorxiv.org/content/10.64898/2025.12.11.693717v1
December 12, 2025 at 11:12 AM
New on bioRxiv! 🧠🧬
Our work uncovers how modularity in the DCC-ECD shapes axon guidance and neuronal migration.Using mouse lines with mutations in Netrin-1 and Draxin binding sites, we show how distinct DCC modules drive precise circuit assembly
#Neuroscience #AxonGuidance #DCC #Netrin1 #Draxin
Our work uncovers how modularity in the DCC-ECD shapes axon guidance and neuronal migration.Using mouse lines with mutations in Netrin-1 and Draxin binding sites, we show how distinct DCC modules drive precise circuit assembly
#Neuroscience #AxonGuidance #DCC #Netrin1 #Draxin
Just published: A new review from Rob Meijers, Shaotong Zhu and Alex Jaworski explores the landscape of #ligandreceptor interactions in #axon pathfinding. Get the lay of the land in our #axonguidance explainer 🧠🟦
#neuroskyence #proteinscience
proteininnovation.org/2025/03/axon...
#neuroskyence #proteinscience
proteininnovation.org/2025/03/axon...
Axon Guidance: Explained
In the late 19th century, neuroscientist Santiago Ramón y Cajal peered through a microscope at the spinal cords of three-day-old chick embryos and drew
proteininnovation.org
March 21, 2025 at 5:01 PM
Just published: A new review from Rob Meijers, Shaotong Zhu and Alex Jaworski explores the landscape of #ligandreceptor interactions in #axon pathfinding. Get the lay of the land in our #axonguidance explainer 🧠🟦
#neuroskyence #proteinscience
proteininnovation.org/2025/03/axon...
#neuroskyence #proteinscience
proteininnovation.org/2025/03/axon...
🥳Our paper on the interplay between mechanical and long range chemical signals in #nervous system #development is now available as a #preprint! www.biorxiv.org/content/10.1...
#mechanobiology #chemicalsignalling #piezo1 #axonguidance #xenopus.
#mechanobiology #chemicalsignalling #piezo1 #axonguidance #xenopus.
Long-range chemical signalling in vivo is regulated by mechanical signals
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
February 16, 2024 at 6:41 PM
🥳Our paper on the interplay between mechanical and long range chemical signals in #nervous system #development is now available as a #preprint! www.biorxiv.org/content/10.1...
#mechanobiology #chemicalsignalling #piezo1 #axonguidance #xenopus.
#mechanobiology #chemicalsignalling #piezo1 #axonguidance #xenopus.
We just released new antibodies targeting UNC5A, as part of our expanding Axon Guidance Antibody Collection!
Find out more about our 🧪
buff.ly/YlqEaXi
#unc5a #axonguidance #recombinantantibodies #proteintools
Find out more about our 🧪
buff.ly/YlqEaXi
#unc5a #axonguidance #recombinantantibodies #proteintools
September 22, 2026 at 8:50 PM
We just released new antibodies targeting UNC5A, as part of our expanding Axon Guidance Antibody Collection!
Find out more about our 🧪
buff.ly/YlqEaXi
#unc5a #axonguidance #recombinantantibodies #proteintools
Find out more about our 🧪
buff.ly/YlqEaXi
#unc5a #axonguidance #recombinantantibodies #proteintools
Attending the Neuronal Connectivity meeting @cshlnews.bsky.social this week? Check out Nirakar Basnet’s poster to learn about our #axonguidance & #synapticfunction antibodies!
Not going? View all our panels, including #Netrin/DCC, #Slit/Robo, #Semaphorin/Plexin & #Eph/Ephrin ➡️ buff.ly/NshB3AJ
Not going? View all our panels, including #Netrin/DCC, #Slit/Robo, #Semaphorin/Plexin & #Eph/Ephrin ➡️ buff.ly/NshB3AJ
September 7, 2026 at 2:15 PM
Attending the Neuronal Connectivity meeting @cshlnews.bsky.social this week? Check out Nirakar Basnet’s poster to learn about our #axonguidance & #synapticfunction antibodies!
Not going? View all our panels, including #Netrin/DCC, #Slit/Robo, #Semaphorin/Plexin & #Eph/Ephrin ➡️ buff.ly/NshB3AJ
Not going? View all our panels, including #Netrin/DCC, #Slit/Robo, #Semaphorin/Plexin & #Eph/Ephrin ➡️ buff.ly/NshB3AJ
New #Robo #Slit antibodies just joined the IPI collections 🧪 Recommended for flow, ICC and IHC, these chimeric #recombinantproteins are specific to human and mouse targets and do not cross-react with other family members.
#axonguidance #neuronalmigration
buff.ly/mtViWPa
#axonguidance #neuronalmigration
buff.ly/mtViWPa
March 31, 2026 at 2:15 PM
New #Robo #Slit antibodies just joined the IPI collections 🧪 Recommended for flow, ICC and IHC, these chimeric #recombinantproteins are specific to human and mouse targets and do not cross-react with other family members.
#axonguidance #neuronalmigration
buff.ly/mtViWPa
#axonguidance #neuronalmigration
buff.ly/mtViWPa
19th century #neuroscientist Santiago Ramón y Cajal peered through a microscope at the #spinalcords of chick embryos and drew what looked like dust mites infiltrating a tomato slice. This moment marked the first step in understanding #axonguidance. Read more 🔬
proteininnovation.org/2025/03/axon...
proteininnovation.org/2025/03/axon...
Axon Guidance: Explained
In the late 19th century, neuroscientist Santiago Ramón y Cajal peered through a microscope at the spinal cords of three-day-old chick embryos and drew
proteininnovation.org
April 9, 2025 at 5:02 PM
19th century #neuroscientist Santiago Ramón y Cajal peered through a microscope at the #spinalcords of chick embryos and drew what looked like dust mites infiltrating a tomato slice. This moment marked the first step in understanding #axonguidance. Read more 🔬
proteininnovation.org/2025/03/axon...
proteininnovation.org/2025/03/axon...
New antibody release!
🧪 Anti-ROBO1 [IPI-ROBO1.81]
🧪 Anti-ROBO3 [IPI-ROBO3.119]
🧪 Anti-ROBO3 [IPI-ROBO3.124]
🧪 Anti-Slit-2 [IPI-Slit2.37]
Use our recombinant monoclonals to study #axonguidance #cellmigration #tissueformation #cytoskelatalorganization, #neuronalwiring & more
buff.ly/oNye2Ky
🧪 Anti-ROBO1 [IPI-ROBO1.81]
🧪 Anti-ROBO3 [IPI-ROBO3.119]
🧪 Anti-ROBO3 [IPI-ROBO3.124]
🧪 Anti-Slit-2 [IPI-Slit2.37]
Use our recombinant monoclonals to study #axonguidance #cellmigration #tissueformation #cytoskelatalorganization, #neuronalwiring & more
buff.ly/oNye2Ky
Axon Guidance Antibody Collection
For neurons to communicate, their axons must navigate precisely to their targets through a complex process known as axon guidance or neuronal migration. This pr
buff.ly
March 16, 2026 at 1:23 PM
New antibody release!
🧪 Anti-ROBO1 [IPI-ROBO1.81]
🧪 Anti-ROBO3 [IPI-ROBO3.119]
🧪 Anti-ROBO3 [IPI-ROBO3.124]
🧪 Anti-Slit-2 [IPI-Slit2.37]
Use our recombinant monoclonals to study #axonguidance #cellmigration #tissueformation #cytoskelatalorganization, #neuronalwiring & more
buff.ly/oNye2Ky
🧪 Anti-ROBO1 [IPI-ROBO1.81]
🧪 Anti-ROBO3 [IPI-ROBO3.119]
🧪 Anti-ROBO3 [IPI-ROBO3.124]
🧪 Anti-Slit-2 [IPI-Slit2.37]
Use our recombinant monoclonals to study #axonguidance #cellmigration #tissueformation #cytoskelatalorganization, #neuronalwiring & more
buff.ly/oNye2Ky
Busy September 17-19? You should be! Join us at #AXON2025 to share research on #synapticplasticity, #braindevelopment, #neuralcircuitry, and more. Early bird registration ends May 1 🦤
#neuroscience #neuroskyence #axonguidance
#neuroscience #neuroskyence #axonguidance
AXON2025 Meeting Rotterdam
Topics Synaptic plasticity Local translation Neuron-glia interactions Brain development and evolution Human models Single cell profiling Advanced imaging technology And more!
axon2025.com
April 15, 2025 at 5:04 PM
Busy September 17-19? You should be! Join us at #AXON2025 to share research on #synapticplasticity, #braindevelopment, #neuralcircuitry, and more. Early bird registration ends May 1 🦤
#neuroscience #neuroskyence #axonguidance
#neuroscience #neuroskyence #axonguidance
Our #nervoussystems rely on organized #axonguidance. In a new review paper, IPI and Brown researchers showcase the growing body of #extracellularinteractome studies that evidence new #receptorcomplexes for axon guidance and reveal extensive #signalcrosstalk.
Expanding ligand-receptor interaction networks for axon guidance: Structural insights into signal crosstalk and specificity
Guidance of nascent axons to their targets is mediated by attractive and repulsive cues that activate receptors on the axonal growth cone.
www.sciencedirect.com
April 2, 2025 at 5:00 PM
Our #nervoussystems rely on organized #axonguidance. In a new review paper, IPI and Brown researchers showcase the growing body of #extracellularinteractome studies that evidence new #receptorcomplexes for axon guidance and reveal extensive #signalcrosstalk.
@kristinpuhl @AxonGuidance this was a young physician. Shld have gotten suspended, punished, remedial ethics & sensitivity training. Minimum
December 3, 2024 at 8:24 AM
@kristinpuhl @AxonGuidance this was a young physician. Shld have gotten suspended, punished, remedial ethics & sensitivity training. Minimum
@kristinpuhl @AxonGuidance but career ending punishment was excessive. When a trainee screws up, you retrain him, remedy his failings
December 3, 2024 at 8:24 AM
@kristinpuhl @AxonGuidance but career ending punishment was excessive. When a trainee screws up, you retrain him, remedy his failings
@AxonGuidance @baileyelise @mcbridetd supposedly doc only involved to pronounce death, not as part of execution, I think.
December 1, 2024 at 10:08 AM
@AxonGuidance @baileyelise @mcbridetd supposedly doc only involved to pronounce death, not as part of execution, I think.
4/7
#FibroAdipogenicProgenitor in PAD
⏫Cytokine response/Proliferation
⏬#AxonGuidance (ROBO1/SEMA3C/5A/EFNA5)/Negative regulators of TGFβ (LTBP1/FBN1/SMURF2/ITGA8)
#FibroAdipogenicProgenitor in PAD
⏫Cytokine response/Proliferation
⏬#AxonGuidance (ROBO1/SEMA3C/5A/EFNA5)/Negative regulators of TGFβ (LTBP1/FBN1/SMURF2/ITGA8)
November 9, 2023 at 9:06 PM
4/7
#FibroAdipogenicProgenitor in PAD
⏫Cytokine response/Proliferation
⏬#AxonGuidance (ROBO1/SEMA3C/5A/EFNA5)/Negative regulators of TGFβ (LTBP1/FBN1/SMURF2/ITGA8)
#FibroAdipogenicProgenitor in PAD
⏫Cytokine response/Proliferation
⏬#AxonGuidance (ROBO1/SEMA3C/5A/EFNA5)/Negative regulators of TGFβ (LTBP1/FBN1/SMURF2/ITGA8)
Always a pleasure to host renowned experts while teaching master courses. Today Dario Bonanomi from @SanRaffaeleMI @ArmeniseHarvard giving a lecture about #axonguidance to #molecularneurobiology students @unipv
January 18, 2025 at 10:50 AM
Always a pleasure to host renowned experts while teaching master courses. Today Dario Bonanomi from @SanRaffaeleMI @ArmeniseHarvard giving a lecture about #axonguidance to #molecularneurobiology students @unipv
They have identified a novel role for the EphA4 protein in visual system development. This discovery challenges established theories on #AxonGuidance by demonstrating that, besides repelling axons, the EphA4 receptor can promote adhesion when it binds to ephrinB1.
January 23, 2025 at 10:31 AM
They have identified a novel role for the EphA4 protein in visual system development. This discovery challenges established theories on #AxonGuidance by demonstrating that, besides repelling axons, the EphA4 receptor can promote adhesion when it binds to ephrinB1.