#CircRes
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annetkiraboc1.bsky.social
Thrilled to announce publication of our paper: Myeloid-Specific JAK2 Contributes to Inflammation & Salt Sensitivity of Blood Pressure” in CircRes!
@ahascience.bsky.social

ahajournals.org/doi/10.1161/CIRCRESEARCH.PAPER

#Hypertension #Inflammation #ScienceImpact
November 16, 2024 at 3:48 AM
annetkiraboc1.bsky.social
Our editorial "Fiber, Fatty Acids, and Blood Pressure: A Gut-Level Solution is now published in #CircRes @ahajournals.bsky.social 👇

www.ahajournals.org/doi/10.1161/...

Highlighting a fantastic paper by @fzmarques.bsky.social 👇

www.ahajournals.org/doi/10.1161/...
February 13, 2025 at 9:43 PM
annetkiraboc1.bsky.social
🎉 Huge thanks to #CircRes @ahajournals.bsky.social outstanding reviewers, including former #KiraboLab former trainee @ashleylpitzer, now Assistant Professor #MeharryMedical #MeharrySOGS! Your commitment to scientific excellence continues to shine. #ProudMentor #WomenInSTEM
January 22, 2025 at 5:47 PM
annetkiraboc1.bsky.social
Congratulations to Dr. Jane Freedman #EditorInChief #CircRes @ahascience.bsky.social on official appointment as #Chair of #VUMC_Medicine & Deputy CEO & Chief Health System Officer 2025! Your visionary #Leadership inspires us all! Excited for the remarkable journey ahead! @vumc-insights.bsky.social
December 3, 2024 at 6:26 PM
annetkiraboc1.bsky.social
Thrilled to see our paper featured on the cover of #CircRes @ahajournals.bsky.social!

🎉 #ET-3/#ETBR signaling in #lymphatic vessel dynamics as a novel player in #kidney disease pathogenesis - potential therapeutic target.

Read more: ahajrnls.org/3WoU9az

@ashleypitzer @Jianyong_zhong @EShelton24
January 18, 2025 at 2:57 AM
annetkiraboc1.bsky.social
Our editorial for this fantastic paper -

www.ahajournals.org/doi/10.1161/...

published in @CircRes @ahajournals.bsky.social is now in pubmed 👇

pubmed.ncbi.nlm.nih.gov/39636968/
December 9, 2024 at 9:30 PM
fzmarques.bsky.social
Our latest paper is now published in @CircRes 🤩

Congratulations to first author @rikeishm and all co-authors 👏

Read the full paper at www.ahajournals.org/doi/10.1161/...

And great thread 🧵 below 👇👇👇
January 30, 2025 at 4:52 AM
annetkiraboc1.bsky.social

Stick to the Script: How Endomucin Keeps the Glycocalyx in Line - our editorial published in
#CircRes @ahajournals.bsky.social

ahajournals.org/doi/10.1161/...
January 2, 2025 at 7:26 PM
annetkiraboc1.bsky.social
Excited to share our manuscript "ET-3/ETBR Mediates Na+-Activated Immune Signaling and Kidney Lymphatic Dynamics" Published in @ahascience.bsky.social @ahajournals.bsky.social #CircRes

ahajournals.org/doi/10.1161/...

Congrats #KiraboLab 1st author #ashleylpitzer
@vumc-insights.bsky.social
December 17, 2024 at 4:18 PM
annetkiraboc1.bsky.social
Interesting breakdown by @fzmarques.bluesky.social & @rikeish.bsky.social on how the gut #microbiome shapes #bloodpressure of their paper published in #CircRes.

📝 Blog: www.marqueslab.com/post/underst…
📄 Paper: www.ahajournals.org/doi/10.1161/�#Hypertensionrtension @ahajournals.bsky.social
February 4, 2025 at 3:20 AM
annetkiraboc1.bsky.social
Honored to contribute to this important review on Epigenetic Regulation of Innate & Adaptive Immune Cells in Salt-Sensitive Hypertension, published in #CircRes

Huge congrats to 1st author Ashley for leading this!

Read it here: ahajrnls.org/40EUrMY

#Hypertension #Epigenetics #ImmuneRegulation
January 18, 2025 at 11:40 PM
haoyin.bsky.social
#LaminarShearStress-KLF2 in #EndothelialCell ⏬BMP signaling ▶️⏬#VascularCalcification in hyperlipidemic🐭

BMP4 BMPER as direct targets of KLF2

LSS
⏫BMPER
⏬BMP4 MGP FST

OsteoSense 680 to image aortic calcification in vivo

#CircRes 2021 @ahascience.bsky.social

www.ahajournals.org/doi/10.1161/...
November 23, 2024 at 8:24 PM
sthilaire.bsky.social
New @ahajournals.bsky.social CircRes podcast #DiscoverCircRes is out! bit.ly/3B4utIJ I highlight Nov papers & chat w/ Drs. Jil Tardiff & Melissa Lynn about their study R92L cardiac troponin T Alters the cardiac troponin C-cardiac troponin I Interface Disrupting PKA-Mediated Relaxation bit.ly/3C0KWhj
Discover CircRes November 2024 | AHA Podcasts
bit.ly
November 22, 2024 at 5:54 PM
sancholab.bsky.social
🧬 New immunotherapy for atherosclerosis @ahajournals.bsky.social #CircRes
Type 1 dendritic cells (cDC1s) promote atherogenic immunity & can be targeted with tolerogenic nanoparticles.
🔗 doi.org/10.1161/CIRC...
#Immunotherapy #Atherosclerosis #Nanomedicine
#CNIC_CARDIO #immunosky #cardiosky
June 22, 2025 at 5:42 PM
haoyin.bsky.social
⏬Mechanosensing & ⏫inflammation of aortic #EndothelialCell as a potential disease driver in #MarfanSyndrome 😎

A novel Marfan🐭➡️early #ThroacicAorticDissection #AorticRupture Fbn1G234D/G234D T50=5 wk

⏬pSMAD2 ↔️pERK1/2

#AortaEd
Hiromi Yanagisawa lab #CircRes 2025
www.ahajournals.org/doi/suppl/10...
May 17, 2025 at 11:15 AM
annetkiraboc1.bsky.social
Our paper "Salt’s Sex-Specific Impact of Gut Microbiota in Hypertension" is now published in #CircRes

ahajournals.org/doi/10.1161/CI…

Thank#DoctorAlbrittonon & 1st autho#selamdesta0000

Editorial to a fantastic paper by Dr. Tao Yang!
December 6, 2024 at 4:16 PM
haoyin.bsky.social
A mouse model of Nose bleeding
#HereditaryHemorrhagicTelangiectasia

Bmx+ Endothelial Cell ALK1 KO🐭

+🧠microhemorrhage
Arterial tortuosity, ectasia
Arteriolar smooth muscle cell wrapping defects
⏬pial/mesenteric arterial tone

@mfnavedo.bsky.social #CircRes 2026
www.ahajournals.org/doi/10.1161/...
March 15, 2026 at 12:37 PM
thaithanhnha.bsky.social
Decoding the Liver-Heart Axis in Cardiometabolic Diseases.

www.ahajournals.org/doi/10.1161/...

#CardioSky #MedSky #CircRes
May 25, 2025 at 2:26 AM
haoyin.bsky.social
VEGFA/VEGFR2/3➡️Rac1-RhoA/ROCK antagonism➡️⏫ #LymphaticEndothelialCell Barrier function in intestinal lacteal capillaries

A discontinuous button-like to continuous zipper-like junctional shift
⏫barrier to chylomicron uptake

#CircRes 2023 @ahajournals.bsky.social
www.ahajournals.org/doi/10.1161/...
September 8, 2025 at 11:44 AM
haoyin.bsky.social
Understanding Thoracic Aortic Disease in Women

♀️➡️3-fold⏫risk of Dissection/Rupture of aneurysmal aortas
♀️➡️40% more likely aortic death

Estrogen
#VascularAging
#ArterialStiffness
Pregnancy & TAD

#AortaEd
#CircRes 2025 @ahajournals.bsky.social
www.ahajournals.org/doi/10.1161/...
May 21, 2025 at 7:46 PM
haoyin.bsky.social
#HemeMetabolism #Bilirubin #Atherosclerosis

Global Blvra/Biliverdin Reductase α KO in Apoe-/-🐭➡️
Bilirubin depletion
⏫Plasma/Arterial Cholesterol
⏫#PlaqueInstability (intraplaque hemorrhage, neutrophil infiltration)

#CircRes 2023 @ahascience.bsky.social
www.ahajournals.org/doi/full/10....
December 17, 2024 at 12:25 PM
haoyin.bsky.social
FGF13 Cardiomyocyte Conduction

Cardiomyocyte Fgf13 KO🐭
👉Sensitive to Cx43 gap junction blocker
⏫QRS duration
⏫Conduction block
⏬Conduction velocity
👉Perturbed Cx43 localization

TurboID FGF13 interactome▶️
FGF13 stabilizes Microtubule
⏫α/β-tubulin

#CircRes 2025
www.ahajournals.org/doi/suppl/10...
December 17, 2025 at 1:36 PM
haoyin.bsky.social
The Lymphatic Vasculature in Cardiac Development & Ischemic Heart Disease

#Lymphoangiocrine #Reelin▶️#Integrinβ1 #Cardiomyocyte
🫀development & regeneration post-cryoinjury/-MI

@lforlymphatics.bsky.social @lymphaticsprox1.bsky.social #CircRes 2023
www.ahajournals.org/doi/10.1161/...
May 28, 2025 at 7:00 PM
haoyin.bsky.social
Metabolo-Epigenetic coupling #SmoothMuscleCell #ArterialCalcification

NR4A3 (⏫in calcified👤🐭aortas ) as a direct transcriptional activator of Glycolysis (ALDOA PFKL)

🤓Lactate ▶️Histone Lactylation H3K18la of PHOSPHO1 gene promoter▶️Calcification

#CircRes 2024
www.ahajournals.org/doi/10.1161/...
November 12, 2024 at 1:21 PM
haoyin.bsky.social
#RNAEditing #PulmonaryArterialHypertension

ADAR1 (both p150 & p110 isoforms) ⬇️in 👤PAH (in 🫁vascular smooth muscle cell)

SMC ADAR1 KO🐭 excerbates PAH

SMC ⏫dsRNA➡️⏫PKR-eIF2B-IFNβ➡️
Macrophage M1 polarization➡️
SMC proliferation

@kekeyuan.bsky.social #CircRes 2025
www.ahajournals.org/doi/10.1161/...
November 23, 2025 at 12:37 PM