🔬 Discover the versatile chemistry of 1-bromoethene-1-sulfonyl fluoride (BrESF) in #SuFEx click chemistry! From #cycloadditions to conjugate additions and #CrossCoupling, explore its potential for late-stage functionalization with Jubi John & co-workers ✨
#sulfur #fluorine
👉 buff.ly/zlSM8z8
#sulfur #fluorine
👉 buff.ly/zlSM8z8
October 2, 2026 at 7:01 AM
🔬 Discover the versatile chemistry of 1-bromoethene-1-sulfonyl fluoride (BrESF) in #SuFEx click chemistry! From #cycloadditions to conjugate additions and #CrossCoupling, explore its potential for late-stage functionalization with Jubi John & co-workers ✨
#sulfur #fluorine
👉 buff.ly/zlSM8z8
#sulfur #fluorine
👉 buff.ly/zlSM8z8
Transition metal-free #CrossCoupling 🚀 Alkyl fluorides + #Organolithiums react under mild heat with liquid-assisted stirring w/o expensive catalysts🔥 Tolerates 3° fluorides & diverse functional groups🧪 This breakthrough by Wolf & co-workers could reshape TM-free coupling chemistry
👉 buff.ly/tWFwGiw
👉 buff.ly/tWFwGiw
November 21, 2025 at 8:01 AM
Transition metal-free #CrossCoupling 🚀 Alkyl fluorides + #Organolithiums react under mild heat with liquid-assisted stirring w/o expensive catalysts🔥 Tolerates 3° fluorides & diverse functional groups🧪 This breakthrough by Wolf & co-workers could reshape TM-free coupling chemistry
👉 buff.ly/tWFwGiw
👉 buff.ly/tWFwGiw
Want to build complex molecules? 🏗️ All-carbon #quaternarycenters are a key building block, but their synthesis remains tricky 🧪 Learn about the new advances in #transitionmetal-catalyzed C(sp³)–C(sp³) #crosscoupling reactions in our review by Shou-Fei Zhu
👉 https://buff.ly/4ht8SJS
👉 https://buff.ly/4ht8SJS
February 19, 2025 at 8:00 AM
Want to build complex molecules? 🏗️ All-carbon #quaternarycenters are a key building block, but their synthesis remains tricky 🧪 Learn about the new advances in #transitionmetal-catalyzed C(sp³)–C(sp³) #crosscoupling reactions in our review by Shou-Fei Zhu
👉 https://buff.ly/4ht8SJS
👉 https://buff.ly/4ht8SJS
👋 Meet the team behind SYNLETT
Today we're introducing Rubén Martín, Associate Editor✨
A leader in #CrossCoupling chemistry, metal catalysis, and C–C bond activation at ICIQ, his research is expanding the frontiers of organic synthesis
🧪 Who's next? Next editor in 2 weeks!
buff.ly/keEY1uU
Today we're introducing Rubén Martín, Associate Editor✨
A leader in #CrossCoupling chemistry, metal catalysis, and C–C bond activation at ICIQ, his research is expanding the frontiers of organic synthesis
🧪 Who's next? Next editor in 2 weeks!
buff.ly/keEY1uU
July 29, 2026 at 7:01 AM
👋 Meet the team behind SYNLETT
Today we're introducing Rubén Martín, Associate Editor✨
A leader in #CrossCoupling chemistry, metal catalysis, and C–C bond activation at ICIQ, his research is expanding the frontiers of organic synthesis
🧪 Who's next? Next editor in 2 weeks!
buff.ly/keEY1uU
Today we're introducing Rubén Martín, Associate Editor✨
A leader in #CrossCoupling chemistry, metal catalysis, and C–C bond activation at ICIQ, his research is expanding the frontiers of organic synthesis
🧪 Who's next? Next editor in 2 weeks!
buff.ly/keEY1uU
From reactive to controllable⚡Dawson Konowalchuk & co-workers introduce an iterative #functionalization approach for heavily substituted cyclobutenes, enabling selective #SuzukiMiyaura arylation of strained rings🧪
#CrossCoupling
👉 buff.ly/aTjB1et
#CrossCoupling
👉 buff.ly/aTjB1et
July 20, 2026 at 7:01 AM
From reactive to controllable⚡Dawson Konowalchuk & co-workers introduce an iterative #functionalization approach for heavily substituted cyclobutenes, enabling selective #SuzukiMiyaura arylation of strained rings🧪
#CrossCoupling
👉 buff.ly/aTjB1et
#CrossCoupling
👉 buff.ly/aTjB1et
New access to unsymmetrical 2-azapyrenes⚗️ Langer & co-workers report a Brønsted acid–mediated alkyne–carbonyl #metathesis strategy to build these previously unknown polycyclic scaffolds✨
#palladium #CrossCoupling
👉 buff.ly/IljnmuF
#palladium #CrossCoupling
👉 buff.ly/IljnmuF
July 15, 2026 at 7:01 AM
New access to unsymmetrical 2-azapyrenes⚗️ Langer & co-workers report a Brønsted acid–mediated alkyne–carbonyl #metathesis strategy to build these previously unknown polycyclic scaffolds✨
#palladium #CrossCoupling
👉 buff.ly/IljnmuF
#palladium #CrossCoupling
👉 buff.ly/IljnmuF
Discover how Elias Picazo's team developed a groundbreaking iron-catalyzed reaction to synthesize
#thioethers
directly from alkyl halides and disulfides💥💡#crosscoupling
#ironcatalysis
Learn more👉 www.thieme-connect.com/products/ejo...
#thioethers
directly from alkyl halides and disulfides💥💡#crosscoupling
#ironcatalysis
Learn more👉 www.thieme-connect.com/products/ejo...
December 31, 2024 at 5:33 AM
Discover how Elias Picazo's team developed a groundbreaking iron-catalyzed reaction to synthesize
#thioethers
directly from alkyl halides and disulfides💥💡#crosscoupling
#ironcatalysis
Learn more👉 www.thieme-connect.com/products/ejo...
#thioethers
directly from alkyl halides and disulfides💥💡#crosscoupling
#ironcatalysis
Learn more👉 www.thieme-connect.com/products/ejo...
Expanding C(sp³) incorporation via #cobalt #catalysis! This Account by L. Reginald Mills & co-workers highlights #Negishi C(sp²)–C(sp³) #CrossCoupling of redox-active alkyl electrophiles, enabling access to pharmaceutically relevant scaffolds🌿
👉 buff.ly/DPOdNSy
👉 buff.ly/DPOdNSy
July 22, 2026 at 7:01 AM
Expanding C(sp³) incorporation via #cobalt #catalysis! This Account by L. Reginald Mills & co-workers highlights #Negishi C(sp²)–C(sp³) #CrossCoupling of redox-active alkyl electrophiles, enabling access to pharmaceutically relevant scaffolds🌿
👉 buff.ly/DPOdNSy
👉 buff.ly/DPOdNSy
Explore a convergent synthetic strategy toward methyl peracetyl hikosaminide, reported by Fujino & Inoue📚, featuring radical–radical #CrossCoupling and a redesigned intermolecular radical addition to aldehydes that improves selectivity and efficiency🚀
#hikizimycin
👉 buff.ly/tJTRlDy
#hikizimycin
👉 buff.ly/tJTRlDy
August 3, 2026 at 7:01 AM
Explore a convergent synthetic strategy toward methyl peracetyl hikosaminide, reported by Fujino & Inoue📚, featuring radical–radical #CrossCoupling and a redesigned intermolecular radical addition to aldehydes that improves selectivity and efficiency🚀
#hikizimycin
👉 buff.ly/tJTRlDy
#hikizimycin
👉 buff.ly/tJTRlDy
Discover the potential of migratory #CrossCoupling for repurposing coupling partners🧪The latest work by Richard Liu and co-workers explores this, while also tackling ortho-isomerization and nucleophile scope. #Palladium #Catalysis
👉 thieme-connect.de/products/ejo...
👉 thieme-connect.de/products/ejo...
June 17, 2025 at 7:50 AM
Discover the potential of migratory #CrossCoupling for repurposing coupling partners🧪The latest work by Richard Liu and co-workers explores this, while also tackling ortho-isomerization and nucleophile scope. #Palladium #Catalysis
👉 thieme-connect.de/products/ejo...
👉 thieme-connect.de/products/ejo...
🔬 One of SynOpen’s most cited articles of 2023/2024!
Explore a decade of transition-metal-catalyzed cross-coupling reactions in this comprehensive review by Anil Kumar & team — from Pd to Fe, Ni & beyond!
👉 www.thieme-connect.com/products/ejo...
#CrossCoupling #Catalysis #Organometallics
Explore a decade of transition-metal-catalyzed cross-coupling reactions in this comprehensive review by Anil Kumar & team — from Pd to Fe, Ni & beyond!
👉 www.thieme-connect.com/products/ejo...
#CrossCoupling #Catalysis #Organometallics
May 13, 2025 at 9:20 AM
🔬 One of SynOpen’s most cited articles of 2023/2024!
Explore a decade of transition-metal-catalyzed cross-coupling reactions in this comprehensive review by Anil Kumar & team — from Pd to Fe, Ni & beyond!
👉 www.thieme-connect.com/products/ejo...
#CrossCoupling #Catalysis #Organometallics
Explore a decade of transition-metal-catalyzed cross-coupling reactions in this comprehensive review by Anil Kumar & team — from Pd to Fe, Ni & beyond!
👉 www.thieme-connect.com/products/ejo...
#CrossCoupling #Catalysis #Organometallics
Dive into the world of substituted alkynes🚀 From #diynes to #enynes, our review by Janine Cossy explores the latest in chemo- & stereoselective C–C bond formation via alkynyl #CrossCoupling, powered by affordable Mn, Fe, Co, Ni & Cu catalysts🔬
#catalysis
👉 buff.ly/YYAbvj5
#catalysis
👉 buff.ly/YYAbvj5
September 15, 2025 at 7:01 AM
Dive into the world of substituted alkynes🚀 From #diynes to #enynes, our review by Janine Cossy explores the latest in chemo- & stereoselective C–C bond formation via alkynyl #CrossCoupling, powered by affordable Mn, Fe, Co, Ni & Cu catalysts🔬
#catalysis
👉 buff.ly/YYAbvj5
#catalysis
👉 buff.ly/YYAbvj5
Jie Zhao unveils a revolutionary method for coupling #ethers using light-activated #zirconium. This opens doors for efficient C(sp³)-C(sp³) bond formation with ✨High Selectivity & ✨Broad Functional Group Tolerance
#catalysis #crosscoupling
👉 www.thieme-connect.com/products/ejo...
#catalysis #crosscoupling
👉 www.thieme-connect.com/products/ejo...
Investigating the Photoactivity of Low-Valent Zirconium Catalyst in Ether Activation
Thieme E-Books & E-Journals
www.thieme-connect.com
January 15, 2025 at 10:13 AM
Jie Zhao unveils a revolutionary method for coupling #ethers using light-activated #zirconium. This opens doors for efficient C(sp³)-C(sp³) bond formation with ✨High Selectivity & ✨Broad Functional Group Tolerance
#catalysis #crosscoupling
👉 www.thieme-connect.com/products/ejo...
#catalysis #crosscoupling
👉 www.thieme-connect.com/products/ejo...
🔔Issue 5 is available! Please read the cover article:
Electrochemically driven reductive coupling of nitroarenes with alkyl bromides by Jiayu Mo 𝘦𝘵 𝘢𝘭.
#Electrochemistry #OrganicSynthesis #CrossCoupling
#Free_to_read
🔗https://doi.org/10.1039/D5QO01269D
Electrochemically driven reductive coupling of nitroarenes with alkyl bromides by Jiayu Mo 𝘦𝘵 𝘢𝘭.
#Electrochemistry #OrganicSynthesis #CrossCoupling
#Free_to_read
🔗https://doi.org/10.1039/D5QO01269D
March 6, 2026 at 10:25 AM
🔔Issue 5 is available! Please read the cover article:
Electrochemically driven reductive coupling of nitroarenes with alkyl bromides by Jiayu Mo 𝘦𝘵 𝘢𝘭.
#Electrochemistry #OrganicSynthesis #CrossCoupling
#Free_to_read
🔗https://doi.org/10.1039/D5QO01269D
Electrochemically driven reductive coupling of nitroarenes with alkyl bromides by Jiayu Mo 𝘦𝘵 𝘢𝘭.
#Electrochemistry #OrganicSynthesis #CrossCoupling
#Free_to_read
🔗https://doi.org/10.1039/D5QO01269D
Ni-catalyzed asymmetric reductive #CrossCoupling 🔥Using a Ni/Biox platform, this method by Qiu & Gong delivers enantioenriched tertiary α-aryl acetals/ketals with steric/electronic effects guiding selectivity✨
#nickel
👉 buff.ly/oyklRSp
#nickel
👉 buff.ly/oyklRSp
March 16, 2026 at 8:01 AM
Ni-catalyzed asymmetric reductive #CrossCoupling 🔥Using a Ni/Biox platform, this method by Qiu & Gong delivers enantioenriched tertiary α-aryl acetals/ketals with steric/electronic effects guiding selectivity✨
#nickel
👉 buff.ly/oyklRSp
#nickel
👉 buff.ly/oyklRSp
Bicyclo[1.1.1]propellane reactivity unlocked🚀 Vasudevan Dhayalan reviews organolithium, Mg, Zn & B-mediated strain-release functionalization⚗️ Mild, regioselective, eco-friendly methods deliver diverse BCPs & amine scaffolds✨
#CrossCoupling
👉 buff.ly/yoME2Sa
#CrossCoupling
👉 buff.ly/yoME2Sa
December 8, 2025 at 8:01 AM
Bicyclo[1.1.1]propellane reactivity unlocked🚀 Vasudevan Dhayalan reviews organolithium, Mg, Zn & B-mediated strain-release functionalization⚗️ Mild, regioselective, eco-friendly methods deliver diverse BCPs & amine scaffolds✨
#CrossCoupling
👉 buff.ly/yoME2Sa
#CrossCoupling
👉 buff.ly/yoME2Sa
First nickel-catalyzed reductive #CrossCoupling of aldehydes & alkenyl halides🚀 Takuya Kurahashi report a stereoconvergent route to allyl alcohols🌟 Enabled by silyl activation & polarity inversion, this strategy tackles a long-standing challenge in synthesis🧪
#nickel
👉 buff.ly/86v9fyB
#nickel
👉 buff.ly/86v9fyB
October 31, 2025 at 8:01 AM
First nickel-catalyzed reductive #CrossCoupling of aldehydes & alkenyl halides🚀 Takuya Kurahashi report a stereoconvergent route to allyl alcohols🌟 Enabled by silyl activation & polarity inversion, this strategy tackles a long-standing challenge in synthesis🧪
#nickel
👉 buff.ly/86v9fyB
#nickel
👉 buff.ly/86v9fyB