Cell Regen Research | A simplified dual-compound cocktail (phenylephrine hydrochloride + harmine) promotes heart regeneration by inducing an embryonic-like cardiomyocyte state!🫀
#HeartRegeneration #StemCells
🔗Check it out: doi.org/10.1186/s136...
#HeartRegeneration #StemCells
🔗Check it out: doi.org/10.1186/s136...
August 31, 2026 at 8:50 AM
Cell Regen Research | A simplified dual-compound cocktail (phenylephrine hydrochloride + harmine) promotes heart regeneration by inducing an embryonic-like cardiomyocyte state!🫀
#HeartRegeneration #StemCells
🔗Check it out: doi.org/10.1186/s136...
#HeartRegeneration #StemCells
🔗Check it out: doi.org/10.1186/s136...
Cell Regen Review | Signaling pathways regulating cardiac regeneration 🫀
Hippo/YAP, Wnt/β-catenin, NRG1-ErbB, MAPK, and Notch orchestrate cardiomyocyte proliferation and repair.
#HeartRegeneration #StemCells
🔗 Full review at: doi.org/10.1186/s136...
Hippo/YAP, Wnt/β-catenin, NRG1-ErbB, MAPK, and Notch orchestrate cardiomyocyte proliferation and repair.
#HeartRegeneration #StemCells
🔗 Full review at: doi.org/10.1186/s136...
July 29, 2026 at 8:39 AM
Cell Regen Review | Signaling pathways regulating cardiac regeneration 🫀
Hippo/YAP, Wnt/β-catenin, NRG1-ErbB, MAPK, and Notch orchestrate cardiomyocyte proliferation and repair.
#HeartRegeneration #StemCells
🔗 Full review at: doi.org/10.1186/s136...
Hippo/YAP, Wnt/β-catenin, NRG1-ErbB, MAPK, and Notch orchestrate cardiomyocyte proliferation and repair.
#HeartRegeneration #StemCells
🔗 Full review at: doi.org/10.1186/s136...
Very proud of this collaboration with Elly Tanaka and Elad Bassat. Jorge Peña @jpenap.bsky.social from our lab skillfully conducted our contributions. @regen-hearts.bsky.social #HeartRegeneration
1/ Can #Axolotls teach us new things about #HeartRegeneration?
A great collaboration between Elly Tanaka and Miguel Torres labs.
We’re happy to share our new work in which we ask how axolotls regenerate their hearts and could they help mammals with that?
doi.org/10.64898/202...
A great collaboration between Elly Tanaka and Miguel Torres labs.
We’re happy to share our new work in which we ask how axolotls regenerate their hearts and could they help mammals with that?
doi.org/10.64898/202...
a cartoon of an axolotl blowing a kiss with a heart in the background .
ALT: a cartoon of an axolotl blowing a kiss with a heart in the background .
media.tenor.com
December 25, 2025 at 8:47 AM
Very proud of this collaboration with Elly Tanaka and Elad Bassat. Jorge Peña @jpenap.bsky.social from our lab skillfully conducted our contributions. @regen-hearts.bsky.social #HeartRegeneration
🚨ISRB Webinar Alert - Zone 3: The Americas📷 Join us on December 19th at 12pm US East Coast Time featuring Ahmed Mahmoud from @sbpdiscovery.bsky.social and Juan Manuel González Rosa from @bostoncollege.bsky.social on #HeartRegeneration🫀 Find all details at isrbio.org/event-6479231
December 16, 2025 at 10:47 PM
🚨ISRB Webinar Alert - Zone 3: The Americas📷 Join us on December 19th at 12pm US East Coast Time featuring Ahmed Mahmoud from @sbpdiscovery.bsky.social and Juan Manuel González Rosa from @bostoncollege.bsky.social on #HeartRegeneration🫀 Find all details at isrbio.org/event-6479231
#CardiacImmunology #HeartRegeneration #DevelopmentalBiology #CardiacNiches #Genomics #InVitroSystems #Technology #Therapeutics #ScienceSky 🧪
May 8, 2025 at 11:43 AM
#PaulKornerSeminar speaker Gabrielle Smith: 'Studying the #epigenome of regenerating cardiomyocytes: how do iPSC-derived cardiomyocytes invoked to re-enter cell cycle compare to animal #HeartRegeneration models?'
@em6wong.bsky.social
@em6wong.bsky.social
June 17, 2025 at 2:50 AM
#PaulKornerSeminar speaker Gabrielle Smith: 'Studying the #epigenome of regenerating cardiomyocytes: how do iPSC-derived cardiomyocytes invoked to re-enter cell cycle compare to animal #HeartRegeneration models?'
@em6wong.bsky.social
@em6wong.bsky.social
#PaulKornerSeminar speaker Gabrielle Smith: 'In Regulatory Systems lab, I am studying chromatin architecture and the #epigenome of cardiomyocytes across multiple animals to understand how genome regulation and evolution have shaped #HeartRegeneration across vertebrates.'
@em6wong.bsky.social
@em6wong.bsky.social
June 17, 2025 at 2:44 AM
#PaulKornerSeminar speaker Gabrielle Smith: 'In Regulatory Systems lab, I am studying chromatin architecture and the #epigenome of cardiomyocytes across multiple animals to understand how genome regulation and evolution have shaped #HeartRegeneration across vertebrates.'
@em6wong.bsky.social
@em6wong.bsky.social
Our final #PaulKornerSeminar speaker for today, Gabrielle Smith, will be presenting: ‘Cardiomyocyte chromatin conformation in regenerative and non-regenerative responses to injury’
#HeartRegeneration #CardioTwitter @em6wong
#HeartRegeneration #CardioTwitter @em6wong
December 10, 2024 at 2:59 AM
Our final #PaulKornerSeminar speaker for today, Gabrielle Smith, will be presenting: ‘Cardiomyocyte chromatin conformation in regenerative and non-regenerative responses to injury’
#HeartRegeneration #CardioTwitter @em6wong
#HeartRegeneration #CardioTwitter @em6wong
September's Star Scientist Dr Amy Nicks is on a mission to find the gene that could be the key to unlocking #HeartRegeneration. She's studying #cardiomyocytes that not only self-repair but are also 'beautiful' structures:#WomeninSTEM
victorchang.edu.au/blog/amy-nicks
victorchang.edu.au/blog/amy-nicks
Star Scientist - Amy Nicks - Victor Chang Cardiac Research Institute
Nominated scientist Dr Amy Nicks is determined to hone in on the gene that could be the key to unlocking heart regeneration.
www.victorchang.edu.au
December 5, 2024 at 2:55 AM
September's Star Scientist Dr Amy Nicks is on a mission to find the gene that could be the key to unlocking #HeartRegeneration. She's studying #cardiomyocytes that not only self-repair but are also 'beautiful' structures:#WomeninSTEM
victorchang.edu.au/blog/amy-nicks
victorchang.edu.au/blog/amy-nicks
#PaulKornerSeminar speaker Dr Amy Nicks: “We developed a new method to capture heart cells in their native state that shows how a baby/neonatal heart cell divides into two cells.” #HeartRegeneration #CellDivision #ConfocalMicroscopy #science #CardiacResearch #HeartResearch
December 5, 2024 at 2:49 AM
#PaulKornerSeminar speaker Dr Amy Nicks: “We developed a new method to capture heart cells in their native state that shows how a baby/neonatal heart cell divides into two cells.” #HeartRegeneration #CellDivision #ConfocalMicroscopy #science #CardiacResearch #HeartResearch
#PaulKornerSeminar speaker Dr Amy Nicks: “Heart cells (or cardiomyocytes) are so beautifully engineered and grow dramatically with age as heart mass increases.” #HeartRegeneration #CellDivision #ConfocalMicroscopy #science #CardiacResearch #HeartResearch
December 5, 2024 at 2:49 AM
#PaulKornerSeminar speaker Dr Amy Nicks: “Heart cells (or cardiomyocytes) are so beautifully engineered and grow dramatically with age as heart mass increases.” #HeartRegeneration #CellDivision #ConfocalMicroscopy #science #CardiacResearch #HeartResearch
A new study in experimental animals reveals a critical difference in how #macrophages help #repair the #heart in #newborns versus #adults after a #HeartAttack, highlighting a fundamental difference in how the #ImmuneSystem drives #healing.
#HeartRegeneration #CardiacRegeneration
#HeartRegeneration #CardiacRegeneration
Heart damage: Why babies recover, but adults scar – BioNews Central
A new study in experimental animals reveals a critical difference in how macrophages help repair the heart in newborns versus adults after a heart attack, highlighting a fundamental difference in how the immune system drives healing. ...
sbee.link
February 12, 2025 at 5:13 AM
A new study in experimental animals reveals a critical difference in how #macrophages help #repair the #heart in #newborns versus #adults after a #HeartAttack, highlighting a fundamental difference in how the #ImmuneSystem drives #healing.
#HeartRegeneration #CardiacRegeneration
#HeartRegeneration #CardiacRegeneration
This review highlights endogenous modulators—TFs, ncRNAs, cyclins, and kinases—as regulators of #cardiomyocyte proliferation, offering insights into awakening #HeartRegeneration pathways and advancing therapies for cardiovascular disease.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
April 13, 2026 at 8:01 AM
This review highlights endogenous modulators—TFs, ncRNAs, cyclins, and kinases—as regulators of #cardiomyocyte proliferation, offering insights into awakening #HeartRegeneration pathways and advancing therapies for cardiovascular disease.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
This review outlines the emerging endogenous key modulators of cardiomyocyte proliferation, elucidates the underlying internal mechanisms of #heartregeneration, and highlights the role of key molecules in the multimodal regulation of pre-existing #CardiomyocyteProliferation.
www.sciencedirect.com
May 29, 2025 at 12:30 PM
This review outlines the emerging endogenous key modulators of cardiomyocyte proliferation, elucidates the underlying internal mechanisms of #heartregeneration, and highlights the role of key molecules in the multimodal regulation of pre-existing #CardiomyocyteProliferation.
Cell Regen Review | Rewiring cardiomyocyte identity & metabolism for heart regeneration! 🫀 Strategies for improving cardiac function in animal models. #HeartRegeneration #StemCells
🔗 More at: doi.org/10.1186/s136...
🔗 More at: doi.org/10.1186/s136...
September 28, 2025 at 8:53 AM
Cell Regen Review | Rewiring cardiomyocyte identity & metabolism for heart regeneration! 🫀 Strategies for improving cardiac function in animal models. #HeartRegeneration #StemCells
🔗 More at: doi.org/10.1186/s136...
🔗 More at: doi.org/10.1186/s136...
Please vote for my #ARTxSCIENCE2025 submission! Voting takes 10 secs
renew.science/artxscience/...
My image shows stem-cell derived heart cells treated with a drug that makes cardiomyocytes (pink) proliferate—without activating fibroblasts #HeartRegeneration #Microscopy #StemCells
renew.science/artxscience/...
My image shows stem-cell derived heart cells treated with a drug that makes cardiomyocytes (pink) proliferate—without activating fibroblasts #HeartRegeneration #Microscopy #StemCells
September 1, 2025 at 12:36 PM
Please vote for my #ARTxSCIENCE2025 submission! Voting takes 10 secs
renew.science/artxscience/...
My image shows stem-cell derived heart cells treated with a drug that makes cardiomyocytes (pink) proliferate—without activating fibroblasts #HeartRegeneration #Microscopy #StemCells
renew.science/artxscience/...
My image shows stem-cell derived heart cells treated with a drug that makes cardiomyocytes (pink) proliferate—without activating fibroblasts #HeartRegeneration #Microscopy #StemCells
More new work from the lab! @idrm.ox.ac.uk @oxforddpag.bsky.social
Do all zebrafish regenerate their hearts equally? Also featuring the Mexican cavefish☺️
Thanks to all co-authors and especially the incredibly talented DPhil student Kostas Lekkos who drove the project. #zebrafish #heartregeneration
Do all zebrafish regenerate their hearts equally? Also featuring the Mexican cavefish☺️
Thanks to all co-authors and especially the incredibly talented DPhil student Kostas Lekkos who drove the project. #zebrafish #heartregeneration
Do zebrafish regenerate their hearts equally? In our new paper at the @tillymommersteeg.bsky.social lab we uncovered variations in the regenerative response of 7 wt zebrafish strains leading us to identify a critical role of oxidative phosphorylation in long-term heart regeneration.
rdcu.be/eI1v5
rdcu.be/eI1v5
Oxidative phosphorylation is required for cardiomyocyte re-differentiation and long-term fish heart regeneration
Nature Cardiovascular Research - Lekkos et al. show that a metabolic switch toward oxidative phosphorylation is required for cardiomyocyte re-differentiation and heart regeneration after injury in...
rdcu.be
October 1, 2025 at 11:41 AM
More new work from the lab! @idrm.ox.ac.uk @oxforddpag.bsky.social
Do all zebrafish regenerate their hearts equally? Also featuring the Mexican cavefish☺️
Thanks to all co-authors and especially the incredibly talented DPhil student Kostas Lekkos who drove the project. #zebrafish #heartregeneration
Do all zebrafish regenerate their hearts equally? Also featuring the Mexican cavefish☺️
Thanks to all co-authors and especially the incredibly talented DPhil student Kostas Lekkos who drove the project. #zebrafish #heartregeneration
New work from the lab! Cellular processes key for successful heart regeneration occur at specific times over 24 hours and disturbing these day-night rhythms affects cardiomyocyte metabolism, cell cycle and regeneration.
#zebrafish #cavefish #heartregeneration
www.linkedin.com/posts/gennar...
#zebrafish #cavefish #heartregeneration
www.linkedin.com/posts/gennar...
A balanced circadian glycolytic rhythm drives cardiomyocyte cell cycle progression during fish heart regeneration | Gennaro Ruggiero
Did you know that our circadian clock—the internal rhythm that regulates our sleep-wake cycle—also plays a crucial role in heart regeneration? Most people don’t, and that’s exactly why I’m excited to ...
www.linkedin.com
September 25, 2025 at 12:49 PM
New work from the lab! Cellular processes key for successful heart regeneration occur at specific times over 24 hours and disturbing these day-night rhythms affects cardiomyocyte metabolism, cell cycle and regeneration.
#zebrafish #cavefish #heartregeneration
www.linkedin.com/posts/gennar...
#zebrafish #cavefish #heartregeneration
www.linkedin.com/posts/gennar...
1/ Can #Axolotls teach us new things about #HeartRegeneration?
A great collaboration between Elly Tanaka and Miguel Torres labs.
We’re happy to share our new work in which we ask how axolotls regenerate their hearts and could they help mammals with that?
doi.org/10.64898/202...
A great collaboration between Elly Tanaka and Miguel Torres labs.
We’re happy to share our new work in which we ask how axolotls regenerate their hearts and could they help mammals with that?
doi.org/10.64898/202...
a cartoon of an axolotl blowing a kiss with a heart in the background .
ALT: a cartoon of an axolotl blowing a kiss with a heart in the background .
media.tenor.com
December 23, 2025 at 10:40 AM
1/ Can #Axolotls teach us new things about #HeartRegeneration?
A great collaboration between Elly Tanaka and Miguel Torres labs.
We’re happy to share our new work in which we ask how axolotls regenerate their hearts and could they help mammals with that?
doi.org/10.64898/202...
A great collaboration between Elly Tanaka and Miguel Torres labs.
We’re happy to share our new work in which we ask how axolotls regenerate their hearts and could they help mammals with that?
doi.org/10.64898/202...