#WeekendRead! #EveryCellIsAnImmuneCell! A new paper @ Immunity shows that stress increases gut permeability, leading to IL1b secretion driving Th17-dependent IL22 production! IL22 suppresses brain #neuron activation dampening stress-induced anxiety! doi.org/10.1016/j.im...
Redirecting
doi.org
December 7, 2024 at 5:53 PM
#WeekendRead! #EveryCellIsAnImmuneCell! A new paper @ Immunity shows that stress increases gut permeability, leading to IL1b secretion driving Th17-dependent IL22 production! IL22 suppresses brain #neuron activation dampening stress-induced anxiety! doi.org/10.1016/j.im...
Get ready to fall in love with every purr of, Jemina, located in Mazon, IL.
Learn more: https://www.petfinder.com/cat/jemina-77706158/il/mazon/just-animals-shelter-il22/
Learn more: https://www.petfinder.com/cat/jemina-77706158/il/mazon/just-animals-shelter-il22/
October 26, 2025 at 4:30 PM
Get ready to fall in love with every purr of, Jemina, located in Mazon, IL.
Learn more: https://www.petfinder.com/cat/jemina-77706158/il/mazon/just-animals-shelter-il22/
Learn more: https://www.petfinder.com/cat/jemina-77706158/il/mazon/just-animals-shelter-il22/
#WeekendRead! #InflammasomePower! @rauchlab.bsky.social &co show @jem.org that small intestinal tufts cells activate the NLRC4 inflammasome leading to PGD2-dependent IL-22 production by ILC3, protecting against Salmonella!
rupress.org/jem/article/...
rupress.org/jem/article/...
Enteric tuft cell inflammasome activation drives NKp46+ILC3 IL22 via PGD2 and inhibits Salmonella
PGD2 released after NAIP-NLRC4 inflammasome activation in tuft cells signals onto ILC3s and mediates host defense mechanisms against Salmonella Typhimurium
rupress.org
March 16, 2025 at 2:57 PM
#WeekendRead! #InflammasomePower! @rauchlab.bsky.social &co show @jem.org that small intestinal tufts cells activate the NLRC4 inflammasome leading to PGD2-dependent IL-22 production by ILC3, protecting against Salmonella!
rupress.org/jem/article/...
rupress.org/jem/article/...
#WeekendRead! #NotAllFatIsEqual! @lexiong.bsky.social Seillet &co show @cp-immunity.bsky.social that #diet saturated fatty acids rapidly impair (while unsaturated fatty acids favor via lipid droplets) IL22 production by ILC3 supporting dysbiosis & gut permeability, exacerbating inflammation!
Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis
Xiong et al. report that short-term, high-fat diet exposure rapidly alters the gut
microbial and immune environment, disrupting tissue homeostasis. IL-22 production
by group 3 innate lymphoid cells (I...
www.cell.com
April 19, 2025 at 2:56 PM
#WeekendRead! #NotAllFatIsEqual! @lexiong.bsky.social Seillet &co show @cp-immunity.bsky.social that #diet saturated fatty acids rapidly impair (while unsaturated fatty acids favor via lipid droplets) IL22 production by ILC3 supporting dysbiosis & gut permeability, exacerbating inflammation!
@biorxivpreprint.bsky.social Atlas of innate immune responses to experimental cholera and IL22 treatment demonstrates protection by mucus-secreting cells
www.biorxiv.org/content/10.1... @harvardmed.bsky.social
www.biorxiv.org/content/10.1... @harvardmed.bsky.social
September 14, 2025 at 5:22 PM
@biorxivpreprint.bsky.social Atlas of innate immune responses to experimental cholera and IL22 treatment demonstrates protection by mucus-secreting cells
www.biorxiv.org/content/10.1... @harvardmed.bsky.social
www.biorxiv.org/content/10.1... @harvardmed.bsky.social
Enteric tuft cell #inflammasome activation drives NKP46⁺ILC3 IL22 via PGD₂ and inhibits #Salmonella, say Madeline Churchill, Ankit Pandeya (@nkeet50.bsky.social), Isabella Rauch (@rauchlab.bsky.social) @ohsunews.bsky.social and colleagues: rupress.org/jem/article/...
#MucosalImmunology
#MucosalImmunology
March 20, 2025 at 8:38 PM
Enteric tuft cell #inflammasome activation drives NKP46⁺ILC3 IL22 via PGD₂ and inhibits #Salmonella, say Madeline Churchill, Ankit Pandeya (@nkeet50.bsky.social), Isabella Rauch (@rauchlab.bsky.social) @ohsunews.bsky.social and colleagues: rupress.org/jem/article/...
#MucosalImmunology
#MucosalImmunology
#ImmunoSky #InflammationSky #DietSky
#ILC3s #Immunity #Inflammation #Mucosa #Metabolism #Nutrition #Diet #IL22
"Trust Your #Gut" & Stay Off those Big Macs 🍔
@wehi-research.bsky.social researchers Cyril Seillet & Friends "Chew the #Fat" in Breaking OPEN ACCESS Study @cp-immunity.bsky.social
#ILC3s #Immunity #Inflammation #Mucosa #Metabolism #Nutrition #Diet #IL22
"Trust Your #Gut" & Stay Off those Big Macs 🍔
@wehi-research.bsky.social researchers Cyril Seillet & Friends "Chew the #Fat" in Breaking OPEN ACCESS Study @cp-immunity.bsky.social
Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis
Xiong et al. report that short-term, high-fat diet exposure rapidly alters the gut
microbial and immune environment, disrupting tissue homeostasis. IL-22 production
by group 3 innate lymphoid cells (I...
www.cell.com
April 14, 2025 at 3:34 PM
#ImmunoSky #InflammationSky #DietSky
#ILC3s #Immunity #Inflammation #Mucosa #Metabolism #Nutrition #Diet #IL22
"Trust Your #Gut" & Stay Off those Big Macs 🍔
@wehi-research.bsky.social researchers Cyril Seillet & Friends "Chew the #Fat" in Breaking OPEN ACCESS Study @cp-immunity.bsky.social
#ILC3s #Immunity #Inflammation #Mucosa #Metabolism #Nutrition #Diet #IL22
"Trust Your #Gut" & Stay Off those Big Macs 🍔
@wehi-research.bsky.social researchers Cyril Seillet & Friends "Chew the #Fat" in Breaking OPEN ACCESS Study @cp-immunity.bsky.social
Ukraine shoots down Russian A-50 surveillance plane and IL-22 command aircraft #EuropeanArmy
https://www.politico.eu/article/ukraine-russia-war-plane-shot-down-a50-il22/
https://www.politico.eu/article/ukraine-russia-war-plane-shot-down-a50-il22/
January 15, 2024 at 1:54 PM
Ukraine shoots down Russian A-50 surveillance plane and IL-22 command aircraft #EuropeanArmy
https://www.politico.eu/article/ukraine-russia-war-plane-shot-down-a50-il22/
https://www.politico.eu/article/ukraine-russia-war-plane-shot-down-a50-il22/
Tucker 🐕
Adult male Golden Retriever
Adoptable from Just Animals Shelter (Mazon, IL)
https://www.petfinder.com/dog/tucker-73115241/il/mazon/just-animals-shelter-il22/
Adult male Golden Retriever
Adoptable from Just Animals Shelter (Mazon, IL)
https://www.petfinder.com/dog/tucker-73115241/il/mazon/just-animals-shelter-il22/
September 11, 2024 at 3:31 PM
Tucker 🐕
Adult male Golden Retriever
Adoptable from Just Animals Shelter (Mazon, IL)
https://www.petfinder.com/dog/tucker-73115241/il/mazon/just-animals-shelter-il22/
Adult male Golden Retriever
Adoptable from Just Animals Shelter (Mazon, IL)
https://www.petfinder.com/dog/tucker-73115241/il/mazon/just-animals-shelter-il22/
High fat foods cause gut inflammation and reduction of IL22
Commentary: www.wehi.edu.au/news/fast-fo...
www.cell.com/immunity/ful...
Commentary: www.wehi.edu.au/news/fast-fo...
www.cell.com/immunity/ful...
Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis
Xiong et al. report that short-term, high-fat diet exposure rapidly alters the gut
microbial and immune environment, disrupting tissue homeostasis. IL-22 production
by group 3 innate lymphoid cells (I...
www.cell.com
May 18, 2025 at 10:28 PM
High fat foods cause gut inflammation and reduction of IL22
Commentary: www.wehi.edu.au/news/fast-fo...
www.cell.com/immunity/ful...
Commentary: www.wehi.edu.au/news/fast-fo...
www.cell.com/immunity/ful...
Sigara içmek IL22 sinyal yolu aracılığıyla pankreas tümörlerinin büyümesini teşvik eder.
Yeni bir çalışma sigara içenlerin pankreas kanserine yakalanma riskinin neden daha yüksek olduğunu açıkladı.
Yeni bir çalışma sigara içenlerin pankreas kanserine yakalanma riskinin neden daha yüksek olduğunu açıkladı.
Study shows how smoking drives pancreatic cancer
Why smokers have a higher chance of developing pancreatic cancer and why they tend to have worse outcomes than nonsmokers, according to a new study by University of Michigan Health Rogel Cancer Center...
www.michiganmedicine.org
September 6, 2025 at 2:46 PM
Sigara içmek IL22 sinyal yolu aracılığıyla pankreas tümörlerinin büyümesini teşvik eder.
Yeni bir çalışma sigara içenlerin pankreas kanserine yakalanma riskinin neden daha yüksek olduğunu açıkladı.
Yeni bir çalışma sigara içenlerin pankreas kanserine yakalanma riskinin neden daha yüksek olduğunu açıkladı.
RRIDs were included in this in Journal of Experimental Medicine paper. We value the author's support of reproducibility. #BetterScience #OpenResearch #methodsmatter
Enteric tuft cell inflammasome activation drives NKp46+ILC3 IL22 via PGD2 and inhibits Salmonella
Read the full paper: Enteric tuft cell inflammasome activation drives NKp46+ILC3 IL22 via PGD2 and inhibits Salmonella
doi.org
March 19, 2026 at 7:02 AM
RRIDs were included in this in Journal of Experimental Medicine paper. We value the author's support of reproducibility. #BetterScience #OpenResearch #methodsmatter
The authors included RRIDs in their in Rxiv paper! We value the author's support of reproducibility. #RRID #BetterScience #reproducibility
Atlas of innate immune responses to experimental cholera and IL22 treatment demonstrates protection by mucus-secreting cells
Read the full paper: Atlas of innate immune responses to experimental cholera and IL22 treatment demonstrates protection by mucus-secreting cells
doi.org
April 29, 2026 at 7:00 AM
The authors included RRIDs in their in Rxiv paper! We value the author's support of reproducibility. #RRID #BetterScience #reproducibility
Out reviewers also said we shouldn’t use IL22 as a read out because Th22 cells are not a real thing… oops
November 22, 2024 at 5:40 AM
Out reviewers also said we shouldn’t use IL22 as a read out because Th22 cells are not a real thing… oops
Cysteine-rich diets increase pool of IL22 secreting CD8 T-cells (amongst others) that help maintain gut health
IL22 regulates intestinal stem cell regeneration
www.nature.com/articles/s41...
IL22 regulates intestinal stem cell regeneration
www.nature.com/articles/s41...
Dietary cysteine enhances intestinal stemness via CD8+ T cell-derived IL-22 - Nature
Dietary cysteine enhances intestinal stem cell-mediated intestinal repair following injury by promoting CD8 T cell-regenerative immune responses.
www.nature.com
October 23, 2025 at 11:27 PM
Cysteine-rich diets increase pool of IL22 secreting CD8 T-cells (amongst others) that help maintain gut health
IL22 regulates intestinal stem cell regeneration
www.nature.com/articles/s41...
IL22 regulates intestinal stem cell regeneration
www.nature.com/articles/s41...
Your lap warmer and quiet companion awaits: Rosalita, located in Mazon, IL.
Learn more: https://www.petfinder.com/cat/rosalita-59355306/il/mazon/just-animals-shelter-il22/
Learn more: https://www.petfinder.com/cat/rosalita-59355306/il/mazon/just-animals-shelter-il22/
Your lap warmer and quiet companion awaits: Rosalita, located in Mazon, IL.
Learn more: https://www.petfinder.com/cat/rosalita-59355306/il/mazon/just-animals-shelter-il22/
dlvr.it
March 30, 2024 at 8:03 PM
Your lap warmer and quiet companion awaits: Rosalita, located in Mazon, IL.
Learn more: https://www.petfinder.com/cat/rosalita-59355306/il/mazon/just-animals-shelter-il22/
Learn more: https://www.petfinder.com/cat/rosalita-59355306/il/mazon/just-animals-shelter-il22/
"Compared to those without autoimmunity, people with lupus have fewer of the T cells that make a protein called interleukin-22, which could help with inflammation and wound healing.”
#AHR #IL22 #lupus #CXCL13 #health #disease #science #autoimmune
www.statnews.com/2024/07/10/l...
#AHR #IL22 #lupus #CXCL13 #health #disease #science #autoimmune
www.statnews.com/2024/07/10/l...
Researchers identify ‘molecular switch’ in lupus that could stymie harmful immune response
A discovery of a "naturally occurring seesaw" in the immune system may help right the balance between helpful and damage-promoting immune cells in people with lupus.
www.statnews.com
July 11, 2024 at 4:29 PM
"Compared to those without autoimmunity, people with lupus have fewer of the T cells that make a protein called interleukin-22, which could help with inflammation and wound healing.”
#AHR #IL22 #lupus #CXCL13 #health #disease #science #autoimmune
www.statnews.com/2024/07/10/l...
#AHR #IL22 #lupus #CXCL13 #health #disease #science #autoimmune
www.statnews.com/2024/07/10/l...
【写真】破損した露軍機Ｉｌ２２はアナパに到達したが修復は不可能＝ウクライナ空軍報道官 www.ukrinform.jp/rubric-ato/3...
破損した露軍機Ｉｌ２２はアナパに到達したが修復は不可能＝ウクライナ�...
ウクライナ空軍のイフナト報道官は１５日、当初撃墜されたと発表され、後に撃墜ではなく、破損であったことが判明した空中指揮機「Ｉｌ２２」��...
www.ukrinform.jp
January 16, 2024 at 8:25 AM
【写真】破損した露軍機Ｉｌ２２はアナパに到達したが修復は不可能＝ウクライナ空軍報道官 www.ukrinform.jp/rubric-ato/3...
ウクライナ空軍、ロシア軍の早期警戒管制機と空中指揮機の撃墜を報告 www.ukrinform.jp/rubric-ato/3...
ウクライナ空軍、ロシア軍の早期警戒管制機と空中指揮機の撃墜を報告
ウクライナ空軍は１５日、ロシア軍の早期警戒管制機「Ａ５０」と空中指揮機「Ｉｌ２２」を撃墜したと公表した。 — ウクルインフォルム.
www.ukrinform.jp
January 15, 2024 at 10:05 AM
ウクライナ空軍、ロシア軍の早期警戒管制機と空中指揮機の撃墜を報告 www.ukrinform.jp/rubric-ato/3...
'Within psoriasis plaques, cross-talk between skin-resident T cells and stroma cells leads to chronic inflammation. Inflammatory cytokines such as TNFα, IL17, IL22, & IL23 amplify the local chronic inflammation and sustain the well-demarcated thick and scaly plaques that characterize the disease'
Skin-resident T Cells Contribute to the Dynamic Disease Manifestations of Psoriasis
Abstract. The human skin forms a dynamic barrier to physical injuries and microbial invasion. Constant interactions between stroma and tissue-confined immu
journals.aai.org
October 29, 2024 at 8:19 AM
'Within psoriasis plaques, cross-talk between skin-resident T cells and stroma cells leads to chronic inflammation. Inflammatory cytokines such as TNFα, IL17, IL22, & IL23 amplify the local chronic inflammation and sustain the well-demarcated thick and scaly plaques that characterize the disease'
Interleukin-22, a potent target for treatment of non-autoimmune diseases #IL22 #MECFS #LongCovid
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Interleukin-22, a potent target for treatment of non-autoimmune diseases
Interleukin −22 (IL-22) is a member of interleukin-10 (IL-10) family cytokines that is produced by different types of lymphocytes included in both innate and adaptive immune systems. These lymphocytes...
pmc.ncbi.nlm.nih.gov
May 5, 2025 at 5:11 PM
Interleukin-22, a potent target for treatment of non-autoimmune diseases #IL22 #MECFS #LongCovid
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...