#SpatialTranscriptomics #Proteomics acute stage of #IschemicStroke (🐭tMCAO 24h)
Molecular drivers of mural cell hyperconstriction & BBB disintegration in post-stroke futile reperfusion?
A dual non-neuronal role of Calcineurin?
@chrstaehr.bsky.social #Stroke 2025
www.ahajournals.org/doi/10.1161/...
Molecular drivers of mural cell hyperconstriction & BBB disintegration in post-stroke futile reperfusion?
A dual non-neuronal role of Calcineurin?
@chrstaehr.bsky.social #Stroke 2025
www.ahajournals.org/doi/10.1161/...
March 28, 2025 at 11:50 AM
#SpatialTranscriptomics #Proteomics acute stage of #IschemicStroke (🐭tMCAO 24h)
Molecular drivers of mural cell hyperconstriction & BBB disintegration in post-stroke futile reperfusion?
A dual non-neuronal role of Calcineurin?
@chrstaehr.bsky.social #Stroke 2025
www.ahajournals.org/doi/10.1161/...
Molecular drivers of mural cell hyperconstriction & BBB disintegration in post-stroke futile reperfusion?
A dual non-neuronal role of Calcineurin?
@chrstaehr.bsky.social #Stroke 2025
www.ahajournals.org/doi/10.1161/...
#LoneStarstroke #Texas #Stroke #IschemicStroke #Afib #DaiWaiOlson Congratulation Dr. Steven J. Warach and Lone Star Stroke Research Team for their recent publication on Jama! Click to the link read jamanetwork.com/journals/jam...
April 3, 2025 at 3:45 PM
#LoneStarstroke #Texas #Stroke #IschemicStroke #Afib #DaiWaiOlson Congratulation Dr. Steven J. Warach and Lone Star Stroke Research Team for their recent publication on Jama! Click to the link read jamanetwork.com/journals/jam...
Vascular Tone of pressurized🐭distal MCA (sham & #IschemicStroke)⏫by BKCa inhibitor
Brain Arterial #EndothelialCell BKca & TRPV4 (immunofluorescence)⏫by acute (0.5~2 h) #Hypoxia or #Stroke across🐁🐀🐖🚶♂️
@chrstaehr.bsky.social #ActaPhysiol 2025
onlinelibrary.wiley.com/doi/10.1111/...
Brain Arterial #EndothelialCell BKca & TRPV4 (immunofluorescence)⏫by acute (0.5~2 h) #Hypoxia or #Stroke across🐁🐀🐖🚶♂️
@chrstaehr.bsky.social #ActaPhysiol 2025
onlinelibrary.wiley.com/doi/10.1111/...
April 2, 2025 at 11:44 AM
Vascular Tone of pressurized🐭distal MCA (sham & #IschemicStroke)⏫by BKCa inhibitor
Brain Arterial #EndothelialCell BKca & TRPV4 (immunofluorescence)⏫by acute (0.5~2 h) #Hypoxia or #Stroke across🐁🐀🐖🚶♂️
@chrstaehr.bsky.social #ActaPhysiol 2025
onlinelibrary.wiley.com/doi/10.1111/...
Brain Arterial #EndothelialCell BKca & TRPV4 (immunofluorescence)⏫by acute (0.5~2 h) #Hypoxia or #Stroke across🐁🐀🐖🚶♂️
@chrstaehr.bsky.social #ActaPhysiol 2025
onlinelibrary.wiley.com/doi/10.1111/...
Another of my friend who had fallen in the #Covid trap a month ago & till in 🏥 with ME . Now paralyzed from the neck down in this 2ndly reinfection .1st reinfection caused #ischemicstroke related #Neurocovid . Be careful out there people …
June 17, 2025 at 10:19 AM
Another of my friend who had fallen in the #Covid trap a month ago & till in 🏥 with ME . Now paralyzed from the neck down in this 2ndly reinfection .1st reinfection caused #ischemicstroke related #Neurocovid . Be careful out there people …
#EPI
Epigenetics is key in ischemic stroke research. Our study maps global trends and highlights emerging areas. 🧠🔍
@GenomeFi
#ischemicstroke #globaltrends
Details: maxapress.com/article/doi/...
Epigenetics is key in ischemic stroke research. Our study maps global trends and highlights emerging areas. 🧠🔍
@GenomeFi
#ischemicstroke #globaltrends
Details: maxapress.com/article/doi/...
March 18, 2025 at 7:22 AM
#EPI
Epigenetics is key in ischemic stroke research. Our study maps global trends and highlights emerging areas. 🧠🔍
@GenomeFi
#ischemicstroke #globaltrends
Details: maxapress.com/article/doi/...
Epigenetics is key in ischemic stroke research. Our study maps global trends and highlights emerging areas. 🧠🔍
@GenomeFi
#ischemicstroke #globaltrends
Details: maxapress.com/article/doi/...
PLA2G4A-mediated lipid imbalance induces myelin injury following #IschemicStroke by impairing microglial phagocytosis, linking disrupted lipid metabolism with neuroinflammation and white matter damage.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
June 8, 2026 at 3:07 PM
PLA2G4A-mediated lipid imbalance induces myelin injury following #IschemicStroke by impairing microglial phagocytosis, linking disrupted lipid metabolism with neuroinflammation and white matter damage.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
#Medsky🧪#Neurosky #pharmasky #drugdelivery #Ischemicstroke affects millions of people annually with limited treatment options targeting #excitotoxicity, a major cause of cognitive impairment. The PSD-95 inhibitor NA-1 has demonstrated neuroprotective potential,
May 8, 2025 at 6:26 AM
#Medsky🧪#Neurosky #pharmasky #drugdelivery #Ischemicstroke affects millions of people annually with limited treatment options targeting #excitotoxicity, a major cause of cognitive impairment. The PSD-95 inhibitor NA-1 has demonstrated neuroprotective potential,
#Medsky🧪 #obgynsky #womenhealth #publichealth Certain hormonal contraceptives are associated with a greater risk of #ischemicstroke & #myocardialinfarction, or #heartattack
@bmj.com
www.bmj.com/content/388/...
The study found that the combined estrogen-progestin pill
@bmj.com
www.bmj.com/content/388/...
The study found that the combined estrogen-progestin pill
Stroke and myocardial infarction with contemporary hormonal contraception: real-world, nationwide, prospective cohort study
Objective To evaluate the association between contemporary hormonal contraceptive use and the risk of incident ischaemic stroke and myocardial infarction.
Design Real-world, nationwide, prospective c...
www.bmj.com
March 22, 2025 at 7:18 AM
#Medsky🧪 #obgynsky #womenhealth #publichealth Certain hormonal contraceptives are associated with a greater risk of #ischemicstroke & #myocardialinfarction, or #heartattack
@bmj.com
www.bmj.com/content/388/...
The study found that the combined estrogen-progestin pill
@bmj.com
www.bmj.com/content/388/...
The study found that the combined estrogen-progestin pill
Iron impairs the redox balance to activate #Necroptosis via the RIPK1-RIPK3-MLKL pathway & increases susceptibility to #Ferroptosis during the early stages of reperfusion post-cerebral #IschemicStroke.
#OpenAccess: https://buff.ly/4huyztc
#OpenAccess: https://buff.ly/4huyztc
January 24, 2025 at 1:00 PM
Iron impairs the redox balance to activate #Necroptosis via the RIPK1-RIPK3-MLKL pathway & increases susceptibility to #Ferroptosis during the early stages of reperfusion post-cerebral #IschemicStroke.
#OpenAccess: https://buff.ly/4huyztc
#OpenAccess: https://buff.ly/4huyztc
Among patients with acute #ischemicstroke and successful endovascular thrombectomy, adjunctive intra-arterial #alteplase increased the proportion achieving excellent functional outcome at 90 days compared with thrombectomy alone.
ja.ma/4dd5a6h
ja.ma/4dd5a6h
May 10, 2026 at 1:00 PM
Among patients with acute #ischemicstroke and successful endovascular thrombectomy, adjunctive intra-arterial #alteplase increased the proportion achieving excellent functional outcome at 90 days compared with thrombectomy alone.
ja.ma/4dd5a6h
ja.ma/4dd5a6h
New research from @uhn.ca's @kbi-uhn.bsky.social reveals that inhibiting an enzyme called SKI-1 may protect the brain after #IschemicStroke by preserving blood vessel integrity. 🧠 This discovery could lead to new targeted therapies that improve recovery.
🔗: www.uhnresearch.ca/news/brain-b...
🔗: www.uhnresearch.ca/news/brain-b...
October 20, 2025 at 8:01 PM
New research from @uhn.ca's @kbi-uhn.bsky.social reveals that inhibiting an enzyme called SKI-1 may protect the brain after #IschemicStroke by preserving blood vessel integrity. 🧠 This discovery could lead to new targeted therapies that improve recovery.
🔗: www.uhnresearch.ca/news/brain-b...
🔗: www.uhnresearch.ca/news/brain-b...
In a new study published in Translational Dental Research, a team of researchers from China introduced a "theragnostic" agent that combines therapy and diagnosis. Learn more: https://ow.ly/tiIB50XZWIB
#teeth #stemcells #QuantumDots #IschemicStroke
#teeth #stemcells #QuantumDots #IschemicStroke
January 29, 2026 at 9:00 AM
In a new study published in Translational Dental Research, a team of researchers from China introduced a "theragnostic" agent that combines therapy and diagnosis. Learn more: https://ow.ly/tiIB50XZWIB
#teeth #stemcells #QuantumDots #IschemicStroke
#teeth #stemcells #QuantumDots #IschemicStroke
This study elucidates the therapeutic potential of a Vitamin D precursor, CCE, in the treatment of #IschemicStroke and the importance of Nrf2 in mediating its neuroprotective effects. #medsky
Click:
Click:
Vitamin D Activates Nrf2 to Prevent Nerve Injury and Reduce Brain Damage in Acute Cerebral Infarction - Current Medical Science
Objective This study aimed to investigate the neuroprotective effects of cholecalciferol cholesterol emulsion (CCE), a vitamin D (VD) precursor, in a murine model of acute cerebral infarction (ACI)…
link.springer.com
September 1, 2025 at 10:49 AM
This study elucidates the therapeutic potential of a Vitamin D precursor, CCE, in the treatment of #IschemicStroke and the importance of Nrf2 in mediating its neuroprotective effects. #medsky
Click:
Click:
Ischemic Stroke: Causes, Symptoms (BE FAST), Diagnosis & Treatment
#IschemicStroke #Neurology #VikaasShandily #MedicalEducation #HealthcareKnowledge
#IschemicStroke #Neurology #VikaasShandily #MedicalEducation #HealthcareKnowledge
April 17, 2026 at 7:07 PM
Ischemic Stroke: Causes, Symptoms (BE FAST), Diagnosis & Treatment
#IschemicStroke #Neurology #VikaasShandily #MedicalEducation #HealthcareKnowledge
#IschemicStroke #Neurology #VikaasShandily #MedicalEducation #HealthcareKnowledge
💬 Editorial: Adjunctive intra-arterial #alteplase after thrombectomy improved excellent outcomes in selected #ischemicstroke patients, but increased mortality and limited generalizability require further investigation.
ja.ma/3OVIsb0
ja.ma/3OVIsb0
May 10, 2026 at 2:00 PM
💬 Editorial: Adjunctive intra-arterial #alteplase after thrombectomy improved excellent outcomes in selected #ischemicstroke patients, but increased mortality and limited generalizability require further investigation.
ja.ma/3OVIsb0
ja.ma/3OVIsb0
Among adults with acute #ischemicstroke treated 4.5 to 24 hours after onset, intravenous #tenecteplase prior to EVT did not increase functional independence or reduce disability compared with EVT alone.
ja.ma/43mJG2v
ja.ma/43mJG2v
June 6, 2026 at 12:00 PM
Among adults with acute #ischemicstroke treated 4.5 to 24 hours after onset, intravenous #tenecteplase prior to EVT did not increase functional independence or reduce disability compared with EVT alone.
ja.ma/43mJG2v
ja.ma/43mJG2v
📊 Research Summary: For adults with acute #ischemicstroke presenting 4.5 to 24 hours after symptom onset, the addition of intravenous #tenecteplase before EVT did not improve 90-day clinical outcomes and showed no significant difference in safety.
ja.ma/4erZvLq
ja.ma/4erZvLq
June 6, 2026 at 1:00 PM
📊 Research Summary: For adults with acute #ischemicstroke presenting 4.5 to 24 hours after symptom onset, the addition of intravenous #tenecteplase before EVT did not improve 90-day clinical outcomes and showed no significant difference in safety.
ja.ma/4erZvLq
ja.ma/4erZvLq
Among patients with acute #ischemicstroke and successful endovascular thrombectomy, adjunctive intra-arterial #alteplase increased the proportion achieving excellent functional outcome at 90 days compared with thrombectomy alone.
ja.ma/4ucLVQQ
ja.ma/4ucLVQQ
June 4, 2026 at 12:00 PM
Among patients with acute #ischemicstroke and successful endovascular thrombectomy, adjunctive intra-arterial #alteplase increased the proportion achieving excellent functional outcome at 90 days compared with thrombectomy alone.
ja.ma/4ucLVQQ
ja.ma/4ucLVQQ
💬 Editorial: Adjunctive intra-arterial #alteplase after thrombectomy improved excellent outcomes in selected #ischemicstroke patients, but increased mortality and limited generalizability require further investigation.
ja.ma/4esZZ4D
ja.ma/4esZZ4D
May 7, 2026 at 3:20 PM
💬 Editorial: Adjunctive intra-arterial #alteplase after thrombectomy improved excellent outcomes in selected #ischemicstroke patients, but increased mortality and limited generalizability require further investigation.
ja.ma/4esZZ4D
ja.ma/4esZZ4D
Can plants protect stroke victims? Study finds kaempferol’s antioxidant properties reduce brain injury. #IschemicStroke #Kaempferol
www.rimpacts.com/rd/p?c=10092... 📄DOI: doi.org/10.1007/s120...
www.rimpacts.com/rd/p?c=10092... 📄DOI: doi.org/10.1007/s120...
The Neuroprotective Mechanisms of Kaempferol in Experimental Ischemic Stroke: A Preclinical Systematic Review
Can plants protect stroke victims? Study finds kaempferol’s antioxidant properties reduce brain injury. #IschemicStroke #Kaempferol
www.rimpacts.com
December 10, 2025 at 4:35 AM
Can plants protect stroke victims? Study finds kaempferol’s antioxidant properties reduce brain injury. #IschemicStroke #Kaempferol
www.rimpacts.com/rd/p?c=10092... 📄DOI: doi.org/10.1007/s120...
www.rimpacts.com/rd/p?c=10092... 📄DOI: doi.org/10.1007/s120...
📊 Research Summary: In acute #ischemicstroke without large or medium vessel occlusion, adjunctive #tirofiban after poor tenecteplase response increased excellent 90-day outcomes without excess bleeding or mortality.
#ESOC2026 @esostroke.bsky.social
ja.ma/4tpMKFM
#ESOC2026 @esostroke.bsky.social
ja.ma/4tpMKFM
May 8, 2026 at 10:15 AM
📊 Research Summary: In acute #ischemicstroke without large or medium vessel occlusion, adjunctive #tirofiban after poor tenecteplase response increased excellent 90-day outcomes without excess bleeding or mortality.
#ESOC2026 @esostroke.bsky.social
ja.ma/4tpMKFM
#ESOC2026 @esostroke.bsky.social
ja.ma/4tpMKFM
Among patients with acute #ischemicstroke and successful endovascular thrombectomy, adjunctive intra-arterial #alteplase increased the proportion achieving excellent functional outcome at 90 days compared with thrombectomy alone.
ja.ma/4d4JWaM
ja.ma/4d4JWaM
May 7, 2026 at 3:15 PM
Among patients with acute #ischemicstroke and successful endovascular thrombectomy, adjunctive intra-arterial #alteplase increased the proportion achieving excellent functional outcome at 90 days compared with thrombectomy alone.
ja.ma/4d4JWaM
ja.ma/4d4JWaM
The Most Potent & Permanent Stroke Recovery Molecule Ever?
Preclinical data highlights NSI-189 driving neurogenesis and ischemic brain recovery in animals only.
#StrokeRecovery #IschemicStroke #NeuroRehab #Neuroplasticity #BrainRecovery
Preclinical data highlights NSI-189 driving neurogenesis and ischemic brain recovery in animals only.
#StrokeRecovery #IschemicStroke #NeuroRehab #Neuroplasticity #BrainRecovery
September 22, 2026 at 9:53 AM
The Most Potent & Permanent Stroke Recovery Molecule Ever?
Preclinical data highlights NSI-189 driving neurogenesis and ischemic brain recovery in animals only.
#StrokeRecovery #IschemicStroke #NeuroRehab #Neuroplasticity #BrainRecovery
Preclinical data highlights NSI-189 driving neurogenesis and ischemic brain recovery in animals only.
#StrokeRecovery #IschemicStroke #NeuroRehab #Neuroplasticity #BrainRecovery
Scientists reveal that Casr-related #neuroprotection induced by ischemic preconditioning (IP) is associated with the transformation of M2 microglia, providing new insights into IP-mediated neuroprotection against #ischemicstroke. #medsky
Read more: link.springer.com/article/10.1...
Read more: link.springer.com/article/10.1...
July 27, 2025 at 2:01 PM
Scientists reveal that Casr-related #neuroprotection induced by ischemic preconditioning (IP) is associated with the transformation of M2 microglia, providing new insights into IP-mediated neuroprotection against #ischemicstroke. #medsky
Read more: link.springer.com/article/10.1...
Read more: link.springer.com/article/10.1...
📊 JAMA Research Summary: In acute #ischemicstroke without large or medium vessel occlusion, adjunctive #tirofiban after poor tenecteplase response increased excellent 90-day outcomes without excess bleeding or mortality.
#ESOC2026 @esostroke.bsky.social
ja.ma/4d6Z8nS
#ESOC2026 @esostroke.bsky.social
ja.ma/4d6Z8nS
May 8, 2026 at 10:15 AM
📊 JAMA Research Summary: In acute #ischemicstroke without large or medium vessel occlusion, adjunctive #tirofiban after poor tenecteplase response increased excellent 90-day outcomes without excess bleeding or mortality.
#ESOC2026 @esostroke.bsky.social
ja.ma/4d6Z8nS
#ESOC2026 @esostroke.bsky.social
ja.ma/4d6Z8nS