Asking new families if they can name at least 5 beta lactams before taking them on.
May 17, 2025 at 10:23 PM
Asking new families if they can name at least 5 beta lactams before taking them on.
A. harticollis is notably resistant to quinolones, tetracyclines, β-lactams, & carbapenems
January 6, 2024 at 6:10 AM
A. harticollis is notably resistant to quinolones, tetracyclines, β-lactams, & carbapenems
Preventive non–beta-lactam antibiotics linked to higher risk of surgical-site infections
In nearly 350,000 Swiss patients, use of non–beta-lactams before surgery was associated with a nearly two-fold increase in SSI risk compared with beta-lactams.
www.cidrap.umn.edu/a...
In nearly 350,000 Swiss patients, use of non–beta-lactams before surgery was associated with a nearly two-fold increase in SSI risk compared with beta-lactams.
www.cidrap.umn.edu/a...
November 3, 2025 at 9:36 PM
Preventive non–beta-lactam antibiotics linked to higher risk of surgical-site infections
In nearly 350,000 Swiss patients, use of non–beta-lactams before surgery was associated with a nearly two-fold increase in SSI risk compared with beta-lactams.
www.cidrap.umn.edu/a...
In nearly 350,000 Swiss patients, use of non–beta-lactams before surgery was associated with a nearly two-fold increase in SSI risk compared with beta-lactams.
www.cidrap.umn.edu/a...
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social
🚨 According to this publication beta-lactams with the highest seizure potential include: 1) Cefazolin, 2) Cefepime, and 3) PCN-G (Table 1).
doi.org/10.3390/microorganisms9071505
🚨 According to this publication beta-lactams with the highest seizure potential include: 1) Cefazolin, 2) Cefepime, and 3) PCN-G (Table 1).
doi.org/10.3390/microorganisms9071505
Beta-Lactams Toxicity in the Intensive Care Unit: An Underestimated Collateral Damage?
Beta-lactams are the most commonly prescribed antimicrobials in intensive care unit (ICU) settings and remain one of the safest antimicrobials prescribed. However, the misdiagnosis of beta-lactam-rela...
doi.org
January 13, 2025 at 2:52 AM
#IDSky #MedSky #PharmSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social @sidpharm.bsky.social
🚨 According to this publication beta-lactams with the highest seizure potential include: 1) Cefazolin, 2) Cefepime, and 3) PCN-G (Table 1).
doi.org/10.3390/microorganisms9071505
🚨 According to this publication beta-lactams with the highest seizure potential include: 1) Cefazolin, 2) Cefepime, and 3) PCN-G (Table 1).
doi.org/10.3390/microorganisms9071505
🆕💫Multicenter matched cohort study
Among 8492 patients hospitalized patients with community-acquired pneumonia, azithromycin was associated with a lower mortality and more hospital free days compared to doxycycline in combination with beta-lactams #idsky #EMIMCC
academic.oup.com/cid/article-...
Among 8492 patients hospitalized patients with community-acquired pneumonia, azithromycin was associated with a lower mortality and more hospital free days compared to doxycycline in combination with beta-lactams #idsky #EMIMCC
academic.oup.com/cid/article-...
Comparative effectiveness of azithromycin versus doxycycline in hospitalized patients with community acquired pneumonia treated with beta-lactams: A multicenter matched cohort study
academic.oup.com
May 16, 2025 at 8:56 PM
🆕💫Multicenter matched cohort study
Among 8492 patients hospitalized patients with community-acquired pneumonia, azithromycin was associated with a lower mortality and more hospital free days compared to doxycycline in combination with beta-lactams #idsky #EMIMCC
academic.oup.com/cid/article-...
Among 8492 patients hospitalized patients with community-acquired pneumonia, azithromycin was associated with a lower mortality and more hospital free days compared to doxycycline in combination with beta-lactams #idsky #EMIMCC
academic.oup.com/cid/article-...
Come to #Microbio26 poster 192 to hear how @charisthompson.bsky.social is sensitising mycobacteria to beta-lactams by making them flip their wall-building strategy #MicroSky
April 14, 2026 at 2:53 PM
Come to #Microbio26 poster 192 to hear how @charisthompson.bsky.social is sensitising mycobacteria to beta-lactams by making them flip their wall-building strategy #MicroSky
I like my beta lactams a lil smoky
December 11, 2024 at 11:53 PM
I like my beta lactams a lil smoky
Better outcomes found in hospitalized pneumonia patients treated with azithromycin
Patients with pneumonia who received azithromycin had lower mortality and more hospital-free days than those who received doxycycline in combination with beta-lactams.
www.cidrap.umn.edu/a...
Patients with pneumonia who received azithromycin had lower mortality and more hospital-free days than those who received doxycycline in combination with beta-lactams.
www.cidrap.umn.edu/a...
Better outcomes found in hospitalized pneumonia patients treated with azithromycin
Analysis of hospitalized patients with community-acquired pneumonia links azithromycin to lower mortality and more hospital-free days compared with doxycycline in combination with beta-lactams.
www.cidrap.umn.edu
May 19, 2025 at 8:51 PM
Better outcomes found in hospitalized pneumonia patients treated with azithromycin
Patients with pneumonia who received azithromycin had lower mortality and more hospital-free days than those who received doxycycline in combination with beta-lactams.
www.cidrap.umn.edu/a...
Patients with pneumonia who received azithromycin had lower mortality and more hospital-free days than those who received doxycycline in combination with beta-lactams.
www.cidrap.umn.edu/a...
Great to have @carokobras.bsky.social presenting her work on #bacterial strategies against #beta-lactams part of @cbcb-newcastle.bsky.social celebration day!
June 8, 2026 at 1:00 PM
Great to have @carokobras.bsky.social presenting her work on #bacterial strategies against #beta-lactams part of @cbcb-newcastle.bsky.social celebration day!
I got bitten by a radioactive staphylococcus and the only superpower I got was being able to cleave beta-lactams
April 17, 2026 at 5:37 PM
I got bitten by a radioactive staphylococcus and the only superpower I got was being able to cleave beta-lactams
🆕💫Navigating the Muddled Middle:
A Case-Based Exploration of Oral β-Lactams for Systemic Gram-Negative Infections
The authors explore the utility of oral β-lactams for treatment of systemic GN infections through 3 hypothetical case scenarios #idsky #EMIMCC
academic.oup.com/ofid/article...
A Case-Based Exploration of Oral β-Lactams for Systemic Gram-Negative Infections
The authors explore the utility of oral β-lactams for treatment of systemic GN infections through 3 hypothetical case scenarios #idsky #EMIMCC
academic.oup.com/ofid/article...
Navigating the Muddled Middle: A Case-Based Exploration of Oral β-Lactams for Systemic Gram-Negative Infections
We describe 3 common scenarios where oral β-lactams may be used for systemic gram-negative infections, and through a coupling of patient cases, we provide
academic.oup.com
September 3, 2025 at 8:07 PM
🆕💫Navigating the Muddled Middle:
A Case-Based Exploration of Oral β-Lactams for Systemic Gram-Negative Infections
The authors explore the utility of oral β-lactams for treatment of systemic GN infections through 3 hypothetical case scenarios #idsky #EMIMCC
academic.oup.com/ofid/article...
A Case-Based Exploration of Oral β-Lactams for Systemic Gram-Negative Infections
The authors explore the utility of oral β-lactams for treatment of systemic GN infections through 3 hypothetical case scenarios #idsky #EMIMCC
academic.oup.com/ofid/article...
Check out case report on transplant recipient with M. abscessus treated with phage therapy and double B-lactams. Incredible work by Hatfull and Kreiswirth labs.
🧪 #TxID #AMR #IDsky
www.nature.com/articles/s41...
🧪 #TxID #AMR #IDsky
www.nature.com/articles/s41...
Use of epigenetically modified bacteriophage and dual beta-lactams to treat a Mycobacterium abscessus sternal wound infection - Nature Communications
Cristinziano et al. report the use of bacteriophages and dual beta lactam antibiotics to treat a patient with a Mycobacterium abscessus sternal wound infection. One of the phages was epigenetically mo...
www.nature.com
December 7, 2024 at 2:21 PM
Check out case report on transplant recipient with M. abscessus treated with phage therapy and double B-lactams. Incredible work by Hatfull and Kreiswirth labs.
🧪 #TxID #AMR #IDsky
www.nature.com/articles/s41...
🧪 #TxID #AMR #IDsky
www.nature.com/articles/s41...
No gods, no mass-directed automatic purification
Make lactams, not war
Fuck the pol-arity
Make lactams, not war
Fuck the pol-arity
April 20, 2025 at 3:34 PM
No gods, no mass-directed automatic purification
Make lactams, not war
Fuck the pol-arity
Make lactams, not war
Fuck the pol-arity
The Beta Lactams - Left Behind
YouTube video by BetaLactamsVEVO
youtu.be
January 25, 2025 at 12:13 PM
🆕 Preprint out now on @chemrxiv.bsky.social!
We report a modular flow cascade for the synthesis of γ- & N-substituted γ-lactams via photochemical radical alkylation and cyclization.
Fast, scalable & broad scope!
🔗 chemrxiv.org/engage/chemr...
#FlowChemistry #Photochemistry #Lactams
We report a modular flow cascade for the synthesis of γ- & N-substituted γ-lactams via photochemical radical alkylation and cyclization.
Fast, scalable & broad scope!
🔗 chemrxiv.org/engage/chemr...
#FlowChemistry #Photochemistry #Lactams
June 19, 2025 at 9:37 AM
🆕 Preprint out now on @chemrxiv.bsky.social!
We report a modular flow cascade for the synthesis of γ- & N-substituted γ-lactams via photochemical radical alkylation and cyclization.
Fast, scalable & broad scope!
🔗 chemrxiv.org/engage/chemr...
#FlowChemistry #Photochemistry #Lactams
We report a modular flow cascade for the synthesis of γ- & N-substituted γ-lactams via photochemical radical alkylation and cyclization.
Fast, scalable & broad scope!
🔗 chemrxiv.org/engage/chemr...
#FlowChemistry #Photochemistry #Lactams
If you get hives/welts from Bactrim, and I know you have had MC-like fuckery post-COVID, you should also probably also avoid penicillins, cephalosporins, carbapenems, aminoglycosides, vancomycin, and all β-lactams in general
July 13, 2025 at 6:55 AM
If you get hives/welts from Bactrim, and I know you have had MC-like fuckery post-COVID, you should also probably also avoid penicillins, cephalosporins, carbapenems, aminoglycosides, vancomycin, and all β-lactams in general
Eagerly awaiting more data for oral beta-lactams for GNR bacteremia
#IDSky
#IDSky
Dr Tamma mentions the ongoing GOAT trial (PI Tamma & Cosgrove)
This will be a most needed and important study. clinicaltrials.gov/study/NCT060...
#IDweek2025 #IDsky
This will be a most needed and important study. clinicaltrials.gov/study/NCT060...
#IDweek2025 #IDsky
October 20, 2025 at 1:54 PM
Eagerly awaiting more data for oral beta-lactams for GNR bacteremia
#IDSky
#IDSky
Yup! All beta-lactams and a shitton of the others. I'm surprised you can do rocephin, penicillins and cephalosporins are usually the worst offenders! My options are azithromycin and ciprofloxacin and ciprofloxacin is counterindicated with the EDS :/
December 19, 2025 at 9:19 PM
Yup! All beta-lactams and a shitton of the others. I'm surprised you can do rocephin, penicillins and cephalosporins are usually the worst offenders! My options are azithromycin and ciprofloxacin and ciprofloxacin is counterindicated with the EDS :/
Yup! Any beta-lactams, plus a lot of the rest. I have two I can take without problems (azithromycin and ciprofloxacin, and Cipro is counterindicated with EDS and everything is resistant to azithromycin) and one I can take with *serious* medication support (nitrofurantoin) and that's it
December 19, 2025 at 10:48 PM
Yup! Any beta-lactams, plus a lot of the rest. I have two I can take without problems (azithromycin and ciprofloxacin, and Cipro is counterindicated with EDS and everything is resistant to azithromycin) and one I can take with *serious* medication support (nitrofurantoin) and that's it
#idsky #idweek2025 session 'Beyond 101: Pondering Perplexing Prescribing Issues': Oral Beta-Lactams for Severe Gram-Positive Infections: Ready for Prime Time? by
Dr. Nguyen (U Chicago Med): lots of pearls in this talk. Wanted to share: bioavailability of oral b-lactams @cynth-id.bsky.social
Dr. Nguyen (U Chicago Med): lots of pearls in this talk. Wanted to share: bioavailability of oral b-lactams @cynth-id.bsky.social
January 7, 2026 at 11:55 PM
#idsky #idweek2025 session 'Beyond 101: Pondering Perplexing Prescribing Issues': Oral Beta-Lactams for Severe Gram-Positive Infections: Ready for Prime Time? by
Dr. Nguyen (U Chicago Med): lots of pearls in this talk. Wanted to share: bioavailability of oral b-lactams @cynth-id.bsky.social
Dr. Nguyen (U Chicago Med): lots of pearls in this talk. Wanted to share: bioavailability of oral b-lactams @cynth-id.bsky.social
Beta lactams retuning to find a porin mutation.
Season 2 Episode 7 - Frame 367 out of 2694
April 11, 2025 at 3:41 AM
Beta lactams retuning to find a porin mutation.
Thrilled to share our latest achievement in C-C activation: Downsizing lactams via Rh-catalyzed C-C activation.
www.sciencedirect.com/science/arti...
Congratulations to Rui and Kangmin!
www.sciencedirect.com/science/arti...
Congratulations to Rui and Kangmin!
Downsizing lactams via Rh-catalyzed C–C activation
Ring-contraction reactions are valuable transformations to access harder-to-synthesize smaller-sized rings from more-available larger-sized precursors…
www.sciencedirect.com
June 10, 2025 at 7:08 PM
Thrilled to share our latest achievement in C-C activation: Downsizing lactams via Rh-catalyzed C-C activation.
www.sciencedirect.com/science/arti...
Congratulations to Rui and Kangmin!
www.sciencedirect.com/science/arti...
Congratulations to Rui and Kangmin!
Comparative effectiveness of azithromycin versus doxycycline in hospitalized patients with community acquired pneumonia treated with beta-lactams: A multicenter matched cohort study
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Comparative effectiveness of azithromycin versus doxycycline in hospitalized patients with community acquired pneumonia treated with beta-lactams: A multicenter matched cohort study
Doxycycline is a frequently used alternative treatment for community-acquired pneumonia in hospitalized patients, but the evidence base is limited.
doi.org
May 20, 2025 at 11:24 PM
Comparative effectiveness of azithromycin versus doxycycline in hospitalized patients with community acquired pneumonia treated with beta-lactams: A multicenter matched cohort study
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
New β-lactams allow treating Pseudomonas that were untreatable, but… are they better than previous options?
This meta-analysis of RCTs shows they are not superior to prior alternatives when available: www.ajicjournal.org/article/S019...
👐🏻 Use them wisely, make them last
#PsWatch #AMSsky #IDsky
This meta-analysis of RCTs shows they are not superior to prior alternatives when available: www.ajicjournal.org/article/S019...
👐🏻 Use them wisely, make them last
#PsWatch #AMSsky #IDsky
Effectiveness of novel β-lactams for Pseudomonas aeruginosa infection: A systematic review and meta-analysis
Novel β-lactams have in vitro activity against Pseudomonas aeruginosa (PA), but their
clinical performances and the selection criteria for practical use are still not clear.
We aimed to evaluate the e...
www.ajicjournal.org
November 24, 2024 at 3:19 PM
New β-lactams allow treating Pseudomonas that were untreatable, but… are they better than previous options?
This meta-analysis of RCTs shows they are not superior to prior alternatives when available: www.ajicjournal.org/article/S019...
👐🏻 Use them wisely, make them last
#PsWatch #AMSsky #IDsky
This meta-analysis of RCTs shows they are not superior to prior alternatives when available: www.ajicjournal.org/article/S019...
👐🏻 Use them wisely, make them last
#PsWatch #AMSsky #IDsky
This was our very first video. The song is called “Left Behind” and is a track from our first album “Carbonic.”
youtu.be/qPnctIElwgk?...
youtu.be/qPnctIElwgk?...
The Beta Lactams - Left Behind
YouTube video by BetaLactamsVEVO
youtu.be
December 6, 2024 at 9:51 PM
This was our very first video. The song is called “Left Behind” and is a track from our first album “Carbonic.”
youtu.be/qPnctIElwgk?...
youtu.be/qPnctIElwgk?...