#MetabolicEngineering
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evgenii-protasov.bsky.social
A first-of-its-kind use of a #methanogen for leucine production!
The organism in question: Methanothermobacter marburgensis.
#biotechnology #methane #archaea #MetabolicEngineering
@cp-trendsbiotech.bsky.social
www.sciencedirect.com/science/arti...
August 16, 2026 at 5:41 PM
pabnik.bsky.social
Delighted to join #MetabolicEngineering as Associate Editor w/Sang Yup Lee, Jay Keasling, I. Borodina, C. Maranas & C. Wittmann. I'll handle submissions in #SyntheticMetabolism, #Pseudomonas, #SynBio, new-to-nature #bioproduction & #EnvironmentalBiotechnology!
September 2, 2025 at 4:50 PM
jipb.bsky.social
🍅 Too good to save for #TomatoTuesday! Some great #PlantScience and #MetabolicEngineering of steroidal glycoalkaloids in tomato. @wileylifesci.bsky.social 🍅
November 24, 2025 at 3:15 PM
pabnik.bsky.social
Cascading recombinase memory switch for programmable and stable gene expression in Pseudomonas putida by Javier Hernández @labnikel.bsky.social

#SyntheticBiology #MetabolicEngineering #GeneticCircuit #OpenAccess

academic.oup.com/nar/article/...

@narjournal.bsky.social
Cascading recombinase memory switch for programmable and stable gene expression in Pseudomonas putida
Abstract. Genetic circuits for model bacteria often perform poorly in non-canonical hosts, limiting the deployment of regulatory programs in industrially r
academic.oup.com
June 11, 2026 at 6:54 AM
yeastgenome.bsky.social
🛠️ Bacteria have long had plasmids w/tunable copy numbers. Eukaryotes haven't, until now: new #Yeast platform =stable, programmable gene dosage control across a 109-copy range. Applications from #MetabolicEngineering ➡️ strain preservation

🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...
September 3, 2026 at 9:20 PM
wimi-bio-tech.bsky.social
Meng et al. developed #BPGA, an enzyme-free in vivo Bxb1-ParA recombinase system in standard DH5α E. coli that iteratively stacks #multi-gene plant vectors, demonstrated by assembling a 9-TU, 41.551 kb andrographolide pathway construct. 🌿🤖 #PlantPhysiology #SyntheticBiology #MetabolicEngineering
September 23, 2026 at 7:03 AM
julianverdonk.eurosky.social
Arabidopsis can be engineerded to smell as a rose! @nickdesnoyer.bsky.social and @atinygreencell.bsky.social that means we can also make it smell as a #Petunia!! #MetabolicEngineering #plantscience

www.sciencedirect.com/science/arti...
Model-guided metabolic engineering of 2-phenylethanol in Arabidopsis
2-Phenylethanol (2-PE) is a natural aromatic compound with properties that make it a potential biological oxygenate for petroleum-derived gasoline. In…
www.sciencedirect.com
November 25, 2025 at 2:06 PM
pabnik.bsky.social
#Pseudomonas vancouverensis as a platform for one-carbon (#C1) assimilation and #polyhydroxyalkanoate accumulation, led by Emil C. Ørsted @labnikel.bsky.social

#Biotechnology #MetabolicEngineering #SynBio

www.sciencedirect.com/science/arti...
Pseudomonas vancouverensis as a platform for one-carbon (C1) assimilation and polyhydroxyalkanoate accumulation
Metabolic engineering calls for new bacterial chassis that combine robust metabolic and physiological traits with genetic tractability. We developed P…
www.sciencedirect.com
March 30, 2026 at 5:23 PM
yeastgenome.bsky.social
#Yeast biodiversity + #MachineLearning enable strain/pathway design in other yeasts #MetabolicEngineering

S. cerevisiae
✅genetic tractability
✅robust growth
❌industrial biotech

Y. lipolytica/O. polymorpha
✅thermo/acid resistance
✅amass lipids
❌ genetic tools

www.yeastgenome.org/reference/S1...
December 5, 2025 at 7:02 PM
puckerlabpapers.bsky.social
Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis
doi.org/10.1038/s414...

#Genomics #Withanolides #SpecializedMetabolism #BiosyntheticGeneCluster #LongReadSequencing #MetabolicEngineering #OpenAccess #OpenData
Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis - Nature Communications
Withanolides are plant steroids with potent bioactivities found in many medicinal plants including Withania somnifera, but their biosynthetic pathway is largely unknown. Here, the authors report the g...
doi.org
July 26, 2025 at 10:34 PM
gerrich.bsky.social
Finishing up my thesis:
First appl. of Zymo-Parts in E. coli was a systematic characterization of 15 oxy.-dependent promoters! Tying het. gene expr. in 2-stage processes to shifts from aerobic biomass creation to production phase. #MetabolicEngineering #SynBio
www.sciencedirect.com/science/arti...
Characterizing and utilizing oxygen-dependent promoters for efficient dynamic metabolic engineering
Promoters adjust cellular gene expression in response to internal or external signals and are key elements for implementing dynamic metabolic engineer…
www.sciencedirect.com
November 25, 2024 at 3:03 PM
biodesignresearch.bsky.social
C. glutamicum metabolic engineering expands substrates & products. Challenges & future directions explored! #CorynebacteriumGlutamicum #CellFactories #MetabolicEngineering
Details: doi.org/10.1016/j.bidere.2025.100008
May 22, 2025 at 1:59 PM
pabnik.bsky.social
Implementing synthetic serine cycles in #Pseudomonas putida unlock methanol assimilation in our favorite bug w/carbon conservation, led by ÒscarPuiggené @labnikel.bsky.social · #SynBio #MetabolicEngineering #Methanol published in @cp-trendsbiotech.bsky.social
www.sciencedirect.com/science/arti...
Systematic engineering of synthetic serine cycles in Pseudomonas putida uncovers emergent topologies for methanol assimilation
The urgent need for a circular carbon economy has driven research into sustainable substrates, including one-carbon (C1) compounds. The non-pathogenic…
www.sciencedirect.com
July 7, 2025 at 4:09 PM
bcbtc20206.bsky.social
🌍 Driving Sustainability with Biocatalysis!

📢 Biocatalysis and Biotransformation Congress 2026
🗓️ October 21–22, 2026
📍 San Francisco, California, USA
🏢 Organized by Sciinov Group

#Biocatalysis #Biotransformation #MetabolicEngineering #CircularEconomy #Sustainability #GreenChemistry #Biotech
March 25, 2026 at 5:52 AM
biodesignresearch.bsky.social
Comprehensive review on C. glutamicum metabolic engineering for diverse substrates & biochemicals, challenges & future directions. #MetabolicEngineering #CellFactories #Corynebacterium
Details: doi.org/10.1016/j.bidere.2025.100008
October 28, 2025 at 3:38 PM
effezeta84.bsky.social
And more #metabolicengineering for lignans biosynthesis #chembio
March 18, 2025 at 7:48 PM
nair-lab.bsky.social
The Nair lab is looking for a #post-doc experienced in yeast pathway and genome engineering. Please DM or email me if you are interested!! Please spread the word! #synbio #metabolicengineering
April 22, 2025 at 1:26 PM
bcbtc20206.bsky.social
🔬 Metabolic Engineering Innovations!

Sciinov Group announces the Biocatalysis & Biotransformation Congress 2026 🌍
📅 Oct 21–22, 2026
📍 San Francisco, USA (In-person

Website link: biocatalysiscongress.com/tool
#MetabolicEngineering #Biocatalysis #Biotech #Conference2026
April 1, 2026 at 3:46 AM
gerrich.bsky.social
Another thesis paper post:

Engineering of a new platform strain of Z. mobilis for chemical production utilizing a metabolic flux valve.

We achieved specific productivity for lactate of > 90 mmol gCDW ^−1 h ^−1
#MetabolicEngineering #SynBio
doi.org/10.1186/s129...
A new Zymomonas mobilis platform strain for the efficient production of chemicals - Microbial Cell Factories
Background Zymomonas mobilis is well known for its outstanding ability to produce ethanol with both high specific productivity and with high yield close to the theoretical maximum. The key enzyme in t...
doi.org
December 10, 2024 at 5:08 PM
effezeta84.bsky.social
A nice #metabolicengineering for renewable plastics from Sang Yup Lee’s group
natureportfolio.nature.com Nature Portfolio @natureportfolio.nature.com · Mar 17
A paper in Nature Chemical Biology presents a system that uses E. coli bacteria to create biodegradable plastics. The system may help in the production of plastics with desirable thermal and mechanical properties, using renewable resources. https://go.nature.com/4hEOaGc 🧪
This is figure 4, which shows renewable biosynthesis of two PEAs from glucose as a sole carbon source.
March 18, 2025 at 7:29 PM
m-grininger.bsky.social
With our research, we are one step closer to biotechnological palm oil alternatives 🌱
rdcu.be/e2nbH

📺📻 Featured on TV, radio, and online media, e.g.:
www.tagesschau.de/inland/regio...

#Sustainability #GreenBiotechnology #Biotechnology #SyntheticBiology #MetabolicEngineering #PalmOil #PalmOilFree
February 4, 2026 at 8:37 PM
horticulturer.bsky.social
First anthocyanin-enriched banana via a 5-MYB regulatory network, boosting pigmentation 500-fold with strong antioxidant potential for bio-fortification. #BananaBiofort #Anthocyanin #MetabolicEngineering #FunctionalFoods @academic.oup.com
Details: doi.org/10.1093/hr/u...
A coordinated network of MYB regulators orchestrates anthocyanin biosynthesis in banana
Abstract. Banana, a globally important staple fruit, is naturally deficient in anthocyanins; however, successful engineering of anthocyanin-enriched banana
doi.org
June 12, 2026 at 12:01 PM
remihocq.bsky.social
Our work opens the door to real #MetabolicEngineering in T. kivui.

It grows fast on CO₂ (∼2 h doubling time) with high carbon efficiency—ideal for sustainable fuel and chemical production.

With rapid, iterative genome editing now possible, these applications are within reach!

2/2
May 12, 2025 at 7:33 AM
sunperform.eu
Our partners @w-u-r.bsky.social and @mpimicrobiomarburg.bsky.social demonstrated how synthetic metabolism can outperform the Calvin cycle—nature’s mechanism for CO2 fixation.

Read the full, open-access Nature Microbiology article at doi.org/10.1038/s415...

#SyntheticBiology #MetabolicEngineering
One-carbon fixation via the synthetic reductive glycine pathway exceeds yield of the Calvin cycle - Nature Microbiology
An engineered one-carbon-fixation pathway increases biomass yields of Cupriavidus necator compared with the Calvin cycle and can support future, sustainable bio-based production.
doi.org
March 28, 2025 at 2:04 PM
tushardhamale.bsky.social
Hi everyone
As my PhD at Indian Institute of Technology, Bombay nears completion, I am actively looking for #Postdoctoral research opportunities in area of #SyntheticBiology #MetabolicEngineering #Pseudomonas
April 18, 2026 at 6:17 AM