Interesting title and #SkeletalMuscle paper topic: Identification of a new population of myonuclei during skeletal muscle hypertrophy. #Myoblue tinyurl.com/34azfajk
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tinyurl.com
November 4, 2026 at 3:27 PM
Interesting title and #SkeletalMuscle paper topic: Identification of a new population of myonuclei during skeletal muscle hypertrophy. #Myoblue tinyurl.com/34azfajk
Very interesting #CellCellPress study: In vivo genome-editing therapy for Duchenne muscular dystrophy: Preclinical studies and first-in-human trial. #DMD #CRISPR #Myoblue tinyurl.com/3u5pzzft
tinyurl.com
October 27, 2026 at 3:19 PM
Very interesting #CellCellPress study: In vivo genome-editing therapy for Duchenne muscular dystrophy: Preclinical studies and first-in-human trial. #DMD #CRISPR #Myoblue tinyurl.com/3u5pzzft
New #NatureGenet paper: Population-scale single-nucleus multi-omic profiling of skeletal muscle reveals extensive context-specific genetic regulation. #Myoblue tinyurl.com/34cnhrds
tinyurl.com
October 28, 2026 at 6:08 PM
New #NatureGenet paper: Population-scale single-nucleus multi-omic profiling of skeletal muscle reveals extensive context-specific genetic regulation. #Myoblue tinyurl.com/34cnhrds
New #CellStemCell paper: Niche-reprogramming CAR T therapy improves skeletal muscle regeneration and function in preclinical murine models of Duchenne muscular dystrophy. #Myoblue tinyurl.com/ycxcy6v3
Niche-reprogramming CAR T therapy improves skeletal muscle regeneration and function in preclinical murine models of Duchenne muscular dystrophy
Diao and colleagues identify uPAR as a shared marker of pathogenic macrophage and
fibro-adipogenic progenitor subsets in DMD. Selective depletion of these cells by
uPAR CAR T cells remodels the dystro...
tinyurl.com
October 29, 2026 at 4:42 PM
New #CellStemCell paper: Niche-reprogramming CAR T therapy improves skeletal muscle regeneration and function in preclinical murine models of Duchenne muscular dystrophy. #Myoblue tinyurl.com/ycxcy6v3
New original paper by Jin Young Hong and collaborators:
Polydeoxyribonucleotide attenuates dexamethasone-induced skeletal muscle atrophy by suppressing oxidative stress and regulating muscle protein turnover
doi.org/10.1007/s109...
#myoblue #dexamethasone #Glucocorticoid #Muscle-protein-turnover
Polydeoxyribonucleotide attenuates dexamethasone-induced skeletal muscle atrophy by suppressing oxidative stress and regulating muscle protein turnover
doi.org/10.1007/s109...
#myoblue #dexamethasone #Glucocorticoid #Muscle-protein-turnover
October 15, 2026 at 1:04 PM
New original paper by Jin Young Hong and collaborators:
Polydeoxyribonucleotide attenuates dexamethasone-induced skeletal muscle atrophy by suppressing oxidative stress and regulating muscle protein turnover
doi.org/10.1007/s109...
#myoblue #dexamethasone #Glucocorticoid #Muscle-protein-turnover
Polydeoxyribonucleotide attenuates dexamethasone-induced skeletal muscle atrophy by suppressing oxidative stress and regulating muscle protein turnover
doi.org/10.1007/s109...
#myoblue #dexamethasone #Glucocorticoid #Muscle-protein-turnover
New #review by Shuya Ishii and co-authors:
Temperature dependence of activation of thick and thin filaments in skeletal and cardiac muscles
#myoblue #myosin #actin
doi.org/10.1007/s109...
Temperature dependence of activation of thick and thin filaments in skeletal and cardiac muscles
#myoblue #myosin #actin
doi.org/10.1007/s109...
October 15, 2026 at 12:51 PM
New #review by Shuya Ishii and co-authors:
Temperature dependence of activation of thick and thin filaments in skeletal and cardiac muscles
#myoblue #myosin #actin
doi.org/10.1007/s109...
Temperature dependence of activation of thick and thin filaments in skeletal and cardiac muscles
#myoblue #myosin #actin
doi.org/10.1007/s109...
New research manuscript by Ronaldo André Castelo dos Santos de Almeida and co-authors:
A novel pulley–vest model enables progressive resistance exercise in rats without tail loading.
doi.org/10.1007/s109...
#resistance-exercise #myoblue
A novel pulley–vest model enables progressive resistance exercise in rats without tail loading.
doi.org/10.1007/s109...
#resistance-exercise #myoblue
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doi.org
October 15, 2026 at 12:43 PM
New research manuscript by Ronaldo André Castelo dos Santos de Almeida and co-authors:
A novel pulley–vest model enables progressive resistance exercise in rats without tail loading.
doi.org/10.1007/s109...
#resistance-exercise #myoblue
A novel pulley–vest model enables progressive resistance exercise in rats without tail loading.
doi.org/10.1007/s109...
#resistance-exercise #myoblue
New original article by Sandra Furlan and co-authors:
Cloning and characterization of intermediate Homer1E of human skeletal muscle
#myoblue #HOMER-proteins #skeletal-muscle #isoform
doi.org/10.1007/s109...
Cloning and characterization of intermediate Homer1E of human skeletal muscle
#myoblue #HOMER-proteins #skeletal-muscle #isoform
doi.org/10.1007/s109...
October 15, 2026 at 12:54 PM
New original article by Sandra Furlan and co-authors:
Cloning and characterization of intermediate Homer1E of human skeletal muscle
#myoblue #HOMER-proteins #skeletal-muscle #isoform
doi.org/10.1007/s109...
Cloning and characterization of intermediate Homer1E of human skeletal muscle
#myoblue #HOMER-proteins #skeletal-muscle #isoform
doi.org/10.1007/s109...
Publication of a new research manuscript by Sonu Patel and collaborators:
Hypertrophic cardiomyopathy-linked Tnnc1 variants are associated with distinct myopathic changes in slow skeletal muscle of mice
doi.org/10.1007/s109...
#HCM #cardiomyopathy #myoblue
Hypertrophic cardiomyopathy-linked Tnnc1 variants are associated with distinct myopathic changes in slow skeletal muscle of mice
doi.org/10.1007/s109...
#HCM #cardiomyopathy #myoblue
October 15, 2026 at 12:49 PM
Publication of a new research manuscript by Sonu Patel and collaborators:
Hypertrophic cardiomyopathy-linked Tnnc1 variants are associated with distinct myopathic changes in slow skeletal muscle of mice
doi.org/10.1007/s109...
#HCM #cardiomyopathy #myoblue
Hypertrophic cardiomyopathy-linked Tnnc1 variants are associated with distinct myopathic changes in slow skeletal muscle of mice
doi.org/10.1007/s109...
#HCM #cardiomyopathy #myoblue
Original manuscript by Stherfanni Almeida Lima-Moura & José Eduardo da Silva-Santos
Sex-dependent regulation of #cholinergic responses in the mouse colon: functional evidence for reduced acetylcholinesterase-dependent control and #nitrergic modulation in females
doi.org/10.1007/s109...
#myoblue
Sex-dependent regulation of #cholinergic responses in the mouse colon: functional evidence for reduced acetylcholinesterase-dependent control and #nitrergic modulation in females
doi.org/10.1007/s109...
#myoblue
October 15, 2026 at 1:00 PM
Original manuscript by Stherfanni Almeida Lima-Moura & José Eduardo da Silva-Santos
Sex-dependent regulation of #cholinergic responses in the mouse colon: functional evidence for reduced acetylcholinesterase-dependent control and #nitrergic modulation in females
doi.org/10.1007/s109...
#myoblue
Sex-dependent regulation of #cholinergic responses in the mouse colon: functional evidence for reduced acetylcholinesterase-dependent control and #nitrergic modulation in females
doi.org/10.1007/s109...
#myoblue
New #Cell paper: Multi-omics atlas of chronic exercise. #Exercise #Circadian #Myoblue tinyurl.com/3954an58
Multi-omics atlas of chronic exercise
A 22-tissue multi-omics atlas of chronic exercise is generated, detailing tissue-,
sex-, and time-dependent molecular adaptations and cell-type-specific epigenetic remodeling
in skeletal muscle. The a...
tinyurl.com
October 15, 2026 at 4:24 PM
New #Cell paper: Multi-omics atlas of chronic exercise. #Exercise #Circadian #Myoblue tinyurl.com/3954an58
New #Cell_Metabolism paper: An NAD+-responsive adipose signal coordinates inter-organ defense against muscle atrophy. #Myoblue tinyurl.com/368227ux
An NAD+-responsive adipose signal coordinates inter-organ defense against muscle atrophy
Liang et al. identify an NAD+-responsive adipokine Serpina3n that protects skeletal
muscle against aging- and disease-associated atrophy. NAD+ elevation promotes adipose
Serpina3n production through S...
tinyurl.com
October 15, 2026 at 4:28 PM
New #Cell_Metabolism paper: An NAD+-responsive adipose signal coordinates inter-organ defense against muscle atrophy. #Myoblue tinyurl.com/368227ux
New #TheLancetNeuro paper: Safety and efficacy of delpacibart zotadirsen in Duchenne muscular dystrophy mutations amenable to exon 44 skipping in the USA (EXPLORE44): a randomised, placebo-controlled, double-blind, phase 1/2 trial. #DMD #Myoblue tinyurl.com/5n7vxnnx
Safety and efficacy of delpacibart zotadirsen in Duchenne muscular dystrophy mutations amenable to exon 44 skipping in the USA (EXPLORE44): a randomised, placebo-controlled, double-blind, phase 1/2 tr...
There are no approved exon skipping therapies to treat Duchenne muscular dystrophy due to DMD variants amenable to exon 44 skipping (DMD44). Delpaciba…
tinyurl.com
October 15, 2026 at 2:16 PM
New #TheLancetNeuro paper: Safety and efficacy of delpacibart zotadirsen in Duchenne muscular dystrophy mutations amenable to exon 44 skipping in the USA (EXPLORE44): a randomised, placebo-controlled, double-blind, phase 1/2 trial. #DMD #Myoblue tinyurl.com/5n7vxnnx
New #NatMetabolism paper: Systemic proteomic dynamics of acute exercise reveal genetic links to health and disease. #Myoblue tinyurl.com/bdh8rrbj
tinyurl.com
October 12, 2026 at 4:39 PM
New #NatMetabolism paper: Systemic proteomic dynamics of acute exercise reveal genetic links to health and disease. #Myoblue tinyurl.com/bdh8rrbj
Congrats to #VandanaGupta and colleagues for their new #SkeletalMuscle paper: Klhl41b orchestrates sarcomere assembly and growth to drive skeletal muscle hypertrophy in vivo. #myoblue tinyurl.com/yeud7cyp
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October 8, 2026 at 2:44 PM
Congrats to #VandanaGupta and colleagues for their new #SkeletalMuscle paper: Klhl41b orchestrates sarcomere assembly and growth to drive skeletal muscle hypertrophy in vivo. #myoblue tinyurl.com/yeud7cyp
New #JCI_insight paper: Mechanistic diversity within RLC-dependent myosin ATPase inhibitors differentiates EDG-7500, a diastolic-selective cardiac sarcomere modulator. #Myoblue tinyurl.com/56npu46y
JCI Insight -
Mechanistic diversity within RLC-dependent myosin ATPase inhibitors differentiates EDG-7500, a diastolic-selective cardiac sarcomere modulator
tinyurl.com
September 22, 2026 at 6:47 PM
New #JCI_insight paper: Mechanistic diversity within RLC-dependent myosin ATPase inhibitors differentiates EDG-7500, a diastolic-selective cardiac sarcomere modulator. #Myoblue tinyurl.com/56npu46y
New #SkeletalMuscle paper: fishROI: a specialized workflow for semi-automated muscle morphometry analysis in teleosts. #Myoblue tinyurl.com/2p9rkp9z
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September 16, 2026 at 1:24 PM
New #SkeletalMuscle paper: fishROI: a specialized workflow for semi-automated muscle morphometry analysis in teleosts. #Myoblue tinyurl.com/2p9rkp9z
New #SkeletalMuscle paper: Assessment of emerin gene transfer in models of X-linked Emery-Dreifuss muscular dystrophy. #EDMD #Myoblue tinyurl.com/4zwwvze9
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September 14, 2026 at 11:51 AM
New #SkeletalMuscle paper: Assessment of emerin gene transfer in models of X-linked Emery-Dreifuss muscular dystrophy. #EDMD #Myoblue tinyurl.com/4zwwvze9
New #SkeletalMuscle paper on Compartment-specific remodeling of skeletal muscle in Duchenne muscular dystrophy. # DMD #Myoblue tinyurl.com/mrxv98wv
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September 10, 2026 at 4:34 PM
New #SkeletalMuscle paper on Compartment-specific remodeling of skeletal muscle in Duchenne muscular dystrophy. # DMD #Myoblue tinyurl.com/mrxv98wv
New #ScienceAdvances paper: Engineering suppressor tRNAs for effective treatment of Duchenne muscular dystrophy. #DMD #Myoblue tinyurl.com/36crszy6
Engineering suppressor tRNAs for effective treatment of Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is a fatal disorder caused by loss of dystrophin, a protein essential for muscle cell integrity. To date, no therapeutic has restored full-length dystrophin. Suppress...
tinyurl.com
September 10, 2026 at 2:38 PM
New #ScienceAdvances paper: Engineering suppressor tRNAs for effective treatment of Duchenne muscular dystrophy. #DMD #Myoblue tinyurl.com/36crszy6
New #Dev_Cell paper from @RelaixLab #Morikis #LeGrandLab1 and colleagues: Postnatal Pax7-expressing limb cells are multipotent and generate non-myogenic lineages that persist into adulthood. #Myoblue tinyurl.com/4btwerez
Postnatal Pax7-expressing limb cells are multipotent and generate non-myogenic lineages that persist into adulthood
Gioftsidi, Hayashi, et al. uncover that in mouse neonatal hindlimb muscles Pax7 progenitors
generate both myogenic and non-myogenic cells, including a specific subpopulation
of fibroblast-like cells, ...
tinyurl.com
August 27, 2026 at 6:43 PM
New #Dev_Cell paper from @RelaixLab #Morikis #LeGrandLab1 and colleagues: Postnatal Pax7-expressing limb cells are multipotent and generate non-myogenic lineages that persist into adulthood. #Myoblue tinyurl.com/4btwerez
Interesting new #NatureAging paper: Contractile myografts confer systemic anti-aging benefits. #Myoblue tinyurl.com/49unvd2s
Contractile myografts confer systemic anti-aging benefits - Nature Aging
Cell and gene therapy are of interest to treat age-related diseases. Here the authors developed subcutaneous transplantation of autologous myocytes to form myografts. Myografts showed a mature vascularized structure, contracted continuously and induced improvements in systemic muscle function, metabolic regulation and tissue regeneration in aged and obese mouse models.
tinyurl.com
August 26, 2026 at 4:54 PM
Interesting new #NatureAging paper: Contractile myografts confer systemic anti-aging benefits. #Myoblue tinyurl.com/49unvd2s
New #jclinicalinvest paper: Immune Cell–Specific SMN Expression and Sustained Immune Alterations in Treated Spinal Muscular Atrophy. #SMA #Myoblue tinyurl.com/3kdmc7wj
JCI -
Immune Cell–Specific SMN Expression and Sustained Immune Alterations in Treated Spinal Muscular Atrophy
tinyurl.com
August 25, 2026 at 5:42 PM
New #jclinicalinvest paper: Immune Cell–Specific SMN Expression and Sustained Immune Alterations in Treated Spinal Muscular Atrophy. #SMA #Myoblue tinyurl.com/3kdmc7wj
New #stemcellreports paper from Brad Olwin's group: TDP-43 sustains satellite cells to maintain and regenerate skeletal muscle. #Myoblue tinyurl.com/4msphru6
TDP-43 sustains satellite cells to maintain and regenerate skeletal muscle
Ewachiw et al. have provided the field with critical insight into the function of
TDP-43 in satellite cells. They bred mice that allowed for the specific and conditional
deletion of TDP-43 specificall...
tinyurl.com
August 20, 2026 at 6:23 PM
New #stemcellreports paper from Brad Olwin's group: TDP-43 sustains satellite cells to maintain and regenerate skeletal muscle. #Myoblue tinyurl.com/4msphru6
May 31, 2025 at 2:51 AM