#CellStemCell
LightNews LightNews
bloodgenes.bsky.social
Delighted to have our work led by #RichardVoit
from our group featured on the cover of #CellStemCell
today. Artwork by the amazing
@drawimpacts.bsky.social:

www.cell.com/cell-stem-ce...

Stay tuned as we work on initiating a clinical trial for this approach!
January 2, 2025 at 4:01 PM
haoyin.bsky.social
A 5-day protocol to generate hiPSC 3D Vascular Organoid😎
ETV2▶️Endothelial Cell
NKX3.1▶️Mural Cell

👉Perfusable, arteriovenous network in vivo
👉⏫Reperfusion in mouse diabetic limb ischemia
👉⏫transplanted islet performance

@meleromartinlab.bsky.social #CellStemCell 2025
www.cell.com/cell-stem-ce...
December 14, 2025 at 12:53 PM
alercher.bsky.social
Chronic autoimmunity rewires metabolism in progenitors, correlating with innate immune memory formation in macrophages that increases antibacterial activity but might also aggravate autoimmune diseases?
shorturl.at/SZ1Ww

#CellStemCell
November 15, 2024 at 10:46 PM
drawimpacts.bsky.social
🎉 Happy New Year from #DrawImpacts Studio! 🎨
We’re thrilled to kick off 2025 with exciting news: our first cover of the year has been selected for #CellStemCell 's first issue of 2025!! To another year of impactful collaborations, science, and creativity—we can’t wait to see what this year brings! 🌟
January 2, 2025 at 8:06 PM
pasquelab.bsky.social
First post on this platform!
Check out our review on"
"Early human development and stem cell-based human embryo models"
@CellStemCell
www.cell.com/cell-stem-ce...
Early human development and stem cell-based human embryo models
Stem cell-based models of the human embryo promise to transform the study of human embryogenesis. In this review, we discuss our current knowledge of the first 2 weeks of human embryo development and ...
www.cell.com
November 11, 2024 at 9:52 PM
haoyin.bsky.social
#TissueEngineeredBloodVessel

Decellularized 👤umbilical cord artery
Seeded: #hiPSC #EndothelialCell
Bioreactor trained: pulsatile unidirec flow 15➡️5 dyn/cm2

Rat #InferiorVenaCava graft▶️
0️⃣Thrombosis
Complete repop by host EC 2 wk SMC 2 mo

#CellStemCell 2025
www.sciencedirect.com/science/arti...
October 1, 2025 at 7:56 PM
haoyin.bsky.social
Grow Flat midbrain organoids (up to 800 μm-thick) onto 3D-printed resin vascular network-mimicking meshed tubes (200 μm interval, 200 μm diameter😎) for 3 months

Almost zero hypoxia, necrotic core, or ER stress
⏫Dopaminergic progenitors/neurons

#CellStemCell 2025
www.cell.com/cell-stem-ce...
April 11, 2026 at 12:33 PM
haoyin.bsky.social
#SpatialTranscriptomics #Visium
Human Healthy Skin Wound Healing (This is a Human Trial!🥸 N=7)
D0/1/7/30

Angiogenic niche comprising #EndothelialCell Fibroblast Mφ

Mφ secretome
D1 (inflam) IL1A/B CCL7
D7 (prolif) TGFB C1QB
D30 (remodeling) IGF1 C1QB

#CellStemCell 2024
www.cell.com/cell-stem-ce...
December 27, 2024 at 12:09 PM
haoyin.bsky.social
Sliced hiPSC Cortical Organoid (500 μm thick slicing every 4 weeks + orbital shaking culture) sustains 150 days 🤠

👉Modeling Neurogenesis, Radial Migration & Cortical Lamination
👉Minimal interior hypoxia & apoptosis

#CellStemCell 2020
www.cell.com/cell-stem-ce...
March 23, 2026 at 11:34 AM
castltrastondrs.medsky.network
MedSky🧪#IDSky #NeuroCovid Do we have an explanation for #COVID19 #brainfog and lethargy? Study in @CellStemCell shows the #SARSCoV2 virus triggers #senescence when it infects dopamine neurons; the neurons stop working, inflammation ensues. @BuckInstitute

www.cell.com/cell-stem-ce...
Abstract
January 21, 2024 at 4:33 AM
haoyin.bsky.social
hiPSC-derived venous #EndothelialCell #iVEC

Mesoderm progenitors+VEGFA+FGF2+RA+DAPT

MEF2C as a putative venous endothelial TF

Retain EphB4 venous marker in vivo

Modeling TIE2L914F #VenousMalformation
DRUG-seq #DeepLearning➡️Bosutinib

#CellStemCell 2024
www.sciencedirect.com/science/arti...
December 24, 2024 at 1:07 PM
ella-maru.bsky.social
🧠✨My new cover for @CellStemCell!

My artwork for the paper illustrates an #organ_chip model of the human #spinal_cord designed to study #amyotrophic_lateral_sclerosis (ALS), neurodegenerative disorder with no cure that causes the loss of motor neurons controlling voluntary movement.
October 5, 2025 at 10:45 AM
lozanzi.bsky.social
#WeekendRead! #MomIsAlwaysMom! Dang, Kundu &co show @ CellStemCell that maternal #microbiota imprints the neural and intestinal stem cell compartments of their offsprings via mTOR signaling, leading to long lasting reprogramming of brain & gut functions! Doi.org/10.1016/j.stem.2024.10.003
Redirecting
Doi.org
December 14, 2024 at 4:35 PM
castltrastondrs.medsky.network
MedSky🧪#IDSky #Publichealth #Neuroimmunology #NeuroCovid #LongCovid Monitor #COVID19 patients for Parkinson’s symptoms, scientists say . The Virus infects dopaminergic neurons in brain, study finds, stopping cell division… @CellStemCell

www.cell.com/cell-stem-ce... www.cell.com/cms/attachme...
Abstract
February 7, 2024 at 4:47 PM
mattmuscleguy.bsky.social
New #CellStemCell paper from Helen Blau and colleagues: Multiomic profiling reveals that prostaglandin E2 reverses aged muscle stem cell dysfunction, leading to increased regeneration and strength. #Myoblue tinyurl.com/yvf4cdch
Multiomic profiling reveals that prostaglandin E2 reverses aged muscle stem cell dysfunction, leading to increased regeneration and strength
Wang et al. uncover that aged muscle stem cells have blunted PGE2-EP4 signaling that is critical for their regenerative function. Treatment with exogenous PGE2 reverses age-related defects in muscle s...
tinyurl.com
June 12, 2025 at 4:10 PM
neuralstemcells.bsky.social
Early results from our Luxa Biotech-sponsored and #NEIfunded #ClinicalTrial are out in #CellStemCell. The trial uses an adult RPE stem cell therapy for dry age-related #MacularDegeneration.

Beautiful cover art by Dr. Yangzi Isabel Tian.

Full Text | zurl.co/gQ2bq
@cellpress.bsky.social
#NIHfunded
November 7, 2025 at 3:53 AM
aaguirre1980.bsky.social
Our new paper in Cell Stem Cell introduces human heart–macrophage assembloids — the first, highly sophisticated organoid model of immune–cardiac interactions.

#NAMs #Organoids #CardiacResearch #CellStemCell #AFib #NIH #MSU

Link to the paper: www.cell.com/cell-stem-ce...
Human heart-macrophage assembloids mimic immune-cardiac interactions and enable arrhythmia disease modeling
O’Hern et al. present a novel human heart-macrophage assembloid platform generated by integrating hPSC-derived embryonic monocytes into heart organoids. These tissue-resident macrophages regulate card...
www.cell.com
October 27, 2025 at 6:29 PM
indrasingh.bsky.social
Beyond excited to say my first PhD paper is out today in @CellStemCell 📷. Here, we explored the role of epigenetic heterogeneity on malignant expansion, using a new approach called STRACK
www.cell.com/cell-stem-ce...
Pre-existing stem cell heterogeneity dictates clonal responses to the acquisition of leukemic driver mutations
Singh, Fernandez-Perez, et al. use hematopoietic stem cell barcoding to study clones with and without activation of cancer driver mutations, identifying that pre-existing stem cell states can dictate ...
www.cell.com
February 27, 2025 at 1:48 AM
charlesdussiau.bsky.social
11/11 We gratefully acknowledge support from Association Laurette Fugain and the CSL Behring–Société Française d’Hématologie fund,.

Above all, thank you to the patients and clinical teams who made this work possible.

#Myelofibrosis #MPN #CellStemCell #Spleen #Niche #Microenvironment
August 26, 2026 at 12:51 PM
felipinmtzrmz.bsky.social
🧬 BREAKTHROUGH: Scientists leap forward with bi-paternal offspring!🐭 Surviving to adulthood, this genetic advance could reshape research & medicine overcoming developmental challenges. 🚀 #Science #Genetics #CellStemCell #trends #PhDlife #innovation #ScienceBreakthrough

www.cell.com/cell-stem-ce...
Adult bi-paternal offspring generated through direct modification of imprinted genes in mammals
Li and colleagues successfully generated bi-paternal mice that developed to adulthood by targeting 20 key imprinted loci. This study underscores imprinting gene abnormalities as the primary barrier to...
www.cell.com
February 8, 2025 at 8:26 AM
antoniogolfari.bsky.social
Mentre l'Italia si divide sul truffatore #Vannoni, nei laboratori veri, ricercatori sottopagati... @CellStemCell
November 18, 2024 at 5:28 PM
genomestability.bsky.social
in vitro reconstitution of meiosis including homologous recombination
http://goo.gl/0E9b6h
@CellStemCell
Goo.gl is sunsetting
goo.gl
November 23, 2024 at 10:30 PM
genomestability.bsky.social
New study in @CellStemCell suggests elevated Myc drives many of the phenotypes of #FanconiAnemia in bone marrow and cancer
https://www.sciencedirect.com/science/article/pii/S1934590920304501
November 23, 2024 at 10:45 AM