A tumor’s specific #NRAS mutation could determine the best course for therapy in NRAS-mutant cancers, according to new work in #ScienceSignaling. https://scim.ag/3TmPDuQ
HRAS promotes mutant NRAS–driven transformation with codon and allele specificity
Effectively treating NRAS-mutant cancers may require a combined pan-RAS and HRAS-specific strategy.
scim.ag
September 10, 2026 at 7:54 PM
A tumor’s specific #NRAS mutation could determine the best course for therapy in NRAS-mutant cancers, according to new work in #ScienceSignaling. https://scim.ag/3TmPDuQ
I guess the NRAs donation cheque was sufficient this election!!
What a long week of WTFs!!
What a long week of WTFs!!
January 24, 2025 at 3:05 PM
I guess the NRAs donation cheque was sufficient this election!!
What a long week of WTFs!!
What a long week of WTFs!!
Another male with a gun. No place in safe in the NRAs America 😢😢
December 14, 2025 at 12:49 AM
Another male with a gun. No place in safe in the NRAs America 😢😢
On the other hand Bernard was always in the NRAs pocket....
July 21, 2026 at 2:41 AM
On the other hand Bernard was always in the NRAs pocket....
The NRAs Russian Financial Backers are also to blame.
August 22, 2025 at 9:04 PM
The NRAs Russian Financial Backers are also to blame.
Aipac sucks and is not that politically competent and is nowhere near the NRAs power and influence, ever
August 1, 2026 at 6:19 PM
Aipac sucks and is not that politically competent and is nowhere near the NRAs power and influence, ever
It will never end with the Republicans doing the NRAs bidding.
December 14, 2025 at 12:02 AM
It will never end with the Republicans doing the NRAs bidding.
Tidenes mindfuck hvis NRAs press og 2nd amendment fører til at flere av Trumps verste faller fra
January 27, 2026 at 7:44 AM
Tidenes mindfuck hvis NRAs press og 2nd amendment fører til at flere av Trumps verste faller fra
DeSantis’s hands are soaked in blood, along with the NRAs, and every Republican lawmaker who voted against gun reform.
August 27, 2023 at 1:17 AM
DeSantis’s hands are soaked in blood, along with the NRAs, and every Republican lawmaker who voted against gun reform.
THE NRAs answer is to let fish have guns.
September 28, 2025 at 5:10 AM
THE NRAs answer is to let fish have guns.
Told ya. Thats too slippery a slope for the NRAs liking
September 5, 2025 at 4:26 PM
Told ya. Thats too slippery a slope for the NRAs liking
Just as dishonest as NRAs “thoughts and prayers” isn’t it. Disgusting.
June 4, 2025 at 8:49 PM
Just as dishonest as NRAs “thoughts and prayers” isn’t it. Disgusting.
In the oral arguments and the unanimous opinion in NRA v. Vullo, SCOTUS accepted the NRAs story as maybe the most dispositive fact. I always thought it was mostly made up.
A secret meeting between an NY regulator and an insurance exec has been pivotal to #NRA lawsuit that led to #SCOTUS win earlier this year. But the participants tell me the purported meeting never happened. (NRA disputes their account.) www.nytimes.com/2024/12/09/u...
After N.R.A.’s Supreme Court Win, a Dispute Over Key Facts
The Supreme Court’s ruling in favor of the N.R.A. in May hinged on a secret meeting involving a New York regulator. The participants say it didn’t happen.
www.nytimes.com
December 10, 2024 at 1:47 AM
In the oral arguments and the unanimous opinion in NRA v. Vullo, SCOTUS accepted the NRAs story as maybe the most dispositive fact. I always thought it was mostly made up.
Engineering NRas palmitoylation to hook zDHHC inhibitors
Engineering NRas palmitoylation to hook zDHHC inhibitors
Protein palmitoylation is an important lipidic post-translation modification catalyzed by the zDHHC protein acyltransferases. In this issue of Cell Chemical Biology, Zhu et al. use an imaginative approach to control NRas palmitoylation and use it as a platform to identify inhibitors of protein palmitoylation.
dlvr.it
May 21, 2026 at 6:30 PM
Engineering NRas palmitoylation to hook zDHHC inhibitors
Picture from the Moray papers, giving them a second reading (NRAS 217)
January 28, 2025 at 7:51 PM
Picture from the Moray papers, giving them a second reading (NRAS 217)
That dipshit Steve Scalise is lucky he had a woman cop there to save his sorry ass, yet he still up NRAs ass.
August 29, 2025 at 1:20 AM
That dipshit Steve Scalise is lucky he had a woman cop there to save his sorry ass, yet he still up NRAs ass.
The final report on the Iberia Peninsula (Spain and Portugal) blackout is out.
Many will be blaming renewables and talk about inertia: nonsense.
The cause was bad voltage control.
Solar and wind could have helped but that was illegal.
The fix is is surprisingly easy.
www.entsoe.eu/publications...
Many will be blaming renewables and talk about inertia: nonsense.
The cause was bad voltage control.
Solar and wind could have helped but that was illegal.
The fix is is surprisingly easy.
www.entsoe.eu/publications...
28 April 2025 Blackout
The final report of the Expert Panel on the 28 April 2025 blackout in continental Spain and Portugal identifies the causes of the blackout and outlines recommendations to strengthen the resilience of Europe’s interconnected electricity system. It was prepared by a technical Expert Panel of 49 members, including representatives from Transmission System Operators (TSOs), Regional Coordination Centres (RCCs), ACER and National Regulatory Authorities (NRAs), and was chaired by experts from two unaffected TSOs.
www.entsoe.eu
March 20, 2026 at 5:57 PM
The final report on the Iberia Peninsula (Spain and Portugal) blackout is out.
Many will be blaming renewables and talk about inertia: nonsense.
The cause was bad voltage control.
Solar and wind could have helped but that was illegal.
The fix is is surprisingly easy.
www.entsoe.eu/publications...
Many will be blaming renewables and talk about inertia: nonsense.
The cause was bad voltage control.
Solar and wind could have helped but that was illegal.
The fix is is surprisingly easy.
www.entsoe.eu/publications...
It’s the NRAs way to start a domestic arms war. Idk if I’m kidding
April 25, 2025 at 7:32 PM
It’s the NRAs way to start a domestic arms war. Idk if I’m kidding
ABHD17 enzymes remove fatty acids from #membrane proteins like NRas. New work from Holme, Sapia, @labvanni.bsky.social, Conibear et al. show that their activity depends on two mobile regions: an S-acylated N-terminal helix and a loop. https://buff.ly/4b3E0xy
February 14, 2025 at 5:58 PM
ABHD17 enzymes remove fatty acids from #membrane proteins like NRas. New work from Holme, Sapia, @labvanni.bsky.social, Conibear et al. show that their activity depends on two mobile regions: an S-acylated N-terminal helix and a loop. https://buff.ly/4b3E0xy
📊 New CEER report: unbundling & certification practices of NRAs, updated since 2024, as well as a first look at hydrogen (HTNO) certification, incl. Poland's GAZ-SYSTEM case.
📄 Read the full report: www.ceer.eu/publication/...
#EnergyRegulation #Hydrogen
📄 Read the full report: www.ceer.eu/publication/...
#EnergyRegulation #Hydrogen
September 24, 2026 at 1:58 PM
📊 New CEER report: unbundling & certification practices of NRAs, updated since 2024, as well as a first look at hydrogen (HTNO) certification, incl. Poland's GAZ-SYSTEM case.
📄 Read the full report: www.ceer.eu/publication/...
#EnergyRegulation #Hydrogen
📄 Read the full report: www.ceer.eu/publication/...
#EnergyRegulation #Hydrogen
Morning🦋
Our local animal shelter is running a fundraiser/competition where the top 13 pets with the most votes ($1 per vote) will feature in the upcoming 2027 calendar🥰
Our Ruby's been entered, if you'd like to play along with a feel-good & wholesome little fundraising activity💙
gogo.photo/657119
Our local animal shelter is running a fundraiser/competition where the top 13 pets with the most votes ($1 per vote) will feature in the upcoming 2027 calendar🥰
Our Ruby's been entered, if you'd like to play along with a feel-good & wholesome little fundraising activity💙
gogo.photo/657119
Vote for Ruby in NRAS Calendar Competition.
Show your support for Northern River Animal Services by voting for Ruby in NRAS Calendar Competition
gogo.photo
June 14, 2026 at 9:59 PM
Morning🦋
Our local animal shelter is running a fundraiser/competition where the top 13 pets with the most votes ($1 per vote) will feature in the upcoming 2027 calendar🥰
Our Ruby's been entered, if you'd like to play along with a feel-good & wholesome little fundraising activity💙
gogo.photo/657119
Our local animal shelter is running a fundraiser/competition where the top 13 pets with the most votes ($1 per vote) will feature in the upcoming 2027 calendar🥰
Our Ruby's been entered, if you'd like to play along with a feel-good & wholesome little fundraising activity💙
gogo.photo/657119
You do realize this is the NRAs people. The confederates finally won after they figured out how to properly cheat.
February 8, 2025 at 2:24 AM
You do realize this is the NRAs people. The confederates finally won after they figured out how to properly cheat.
🧬 World-First Breakthrough!
Peter Mac scientists use #CRISPR to silence cancer-causing mutations like KRAS, NRAS & BRAF, driving aggressive #cancer. This precise method spares healthy #genes, offering new hope for personalised treatments.
Read more: www.petermac.org/about-us/new...
Peter Mac scientists use #CRISPR to silence cancer-causing mutations like KRAS, NRAS & BRAF, driving aggressive #cancer. This precise method spares healthy #genes, offering new hope for personalised treatments.
Read more: www.petermac.org/about-us/new...
December 18, 2024 at 11:32 PM
🧬 World-First Breakthrough!
Peter Mac scientists use #CRISPR to silence cancer-causing mutations like KRAS, NRAS & BRAF, driving aggressive #cancer. This precise method spares healthy #genes, offering new hope for personalised treatments.
Read more: www.petermac.org/about-us/new...
Peter Mac scientists use #CRISPR to silence cancer-causing mutations like KRAS, NRAS & BRAF, driving aggressive #cancer. This precise method spares healthy #genes, offering new hope for personalised treatments.
Read more: www.petermac.org/about-us/new...
TRAF7 mutations stabilize K/NRAS and hyperactivate MAPK signaling to cause CAFDADD neurodevelopmental defects | Science Advances www.science.org/doi/10.1126/...
TRAF7 mutations stabilize K/NRAS and hyperactivate MAPK signaling to cause CAFDADD neurodevelopmental defects
The MAPK-ERK1/2 pathway plays a crucial role in neurodevelopment during embryogenesis, and the hyperactivation of this signaling cascade serves as a pathological hallmark for various neurodevelopmenta...
www.science.org
September 27, 2026 at 12:16 AM
TRAF7 mutations stabilize K/NRAS and hyperactivate MAPK signaling to cause CAFDADD neurodevelopmental defects | Science Advances www.science.org/doi/10.1126/...