#PEM-PostExertionalMalaise
LightNews LightNews
tomkindlon.bsky.social
Post-Exertional Malaise in Long COVID and Post-Vaccine Syndrome: Why “Exercise More” Is the Wrong Answer

drpierrekory.com/blog/post-ex...

Pity that there is only one reference to ME/CFS in the (long) article

Screenshot from October AMMES newsletter

#LongCovid #PostExertionalMalaise #PEM
Image of somebody with their head in their hands with the following text Post-Exertional Malaise in Long COVID and Post-Vaccine Syndrome: Why “Exercise More” Is the Wrong Answer A walk around the block, a few hours of focused work, a social event, or a workout you thought you were finally ready for. It didn’t feel excessive at the time. Then, 12 to 72 hours later, something happened that has no parallel in “normal” human experience. Not tiredness. Not soreness. A complete systemic collapse, with fatigue so profound it feels neurological, brain fog that makes thinking feel like wading through quicksand, muscle pain, sensory sensitivity, and a return of every symptom you thought you’d been making progress on. This is post-exertional malaise. And if you have Long COVID or Post-Vaccine Syndrome, you’ve almost certainly experienced it. What you may not have received is an honest clinical explanation of what it actually is, why it happens, and why the treatment most clinicians prescribe — pushing through, gradually increasing activity, “deconditioning” management — is not just ineffective but genuinely harmful. Read more here>>
October 3, 2026 at 11:57 PM
tomkindlon.bsky.social
The Debt Came Due: Notes From a Crash by @darthfoo.bsky.social

darthfoo.substack.com/p/the-debt-c...

Screenshot from September AMMES newsletter

#MEcfs #LongCovid #PostExertionalMalaise #PEM #PwME
Image of someone lying flat on the sand, looking exhausted with the following text The Debt Came Due: Notes From a Crash "There is a version of my life that exists in my memory like a photograph from a trip I’ll never take again. In that version, I wake up and get out of bed without negotiating with my body first. I drive to work. I talk to people. I solve problems. I go home. I am tired in the way ordinary people are tired, the kind of tired that a night’s sleep fixes. That life is gone. What replaced it has a name. Long COVID. ME/CFS. Post-exertional malaise. The clinical language is clean and distant, which is probably why it fails so completely to describe what it actually feels like to live inside this body right now. Here is what it feels like: I am in a crash." Read more here>>
September 18, 2026 at 12:27 AM
crashmargulies.bsky.social
Full essay, 3,026 words - crashmargulies.dreamwidth.org/35286.html

#MyalgicEncephalomyelitis #LongCOVID #PostExertionalMalaise #SpoonTheory #PENE #PEM #MEcfs #MillionsMissing
September 8, 2026 at 12:08 AM
tomkindlon.bsky.social
From Germany

Registered interventional trials fail to cover patient-prioritised treatments in Post-COVID condition (PCC)

www.researchsquare.com/article/rs-1...

s4me.info/threads/regi...

Screenshot from latest Science for ME weekly update

#LongCovid #PostExertionalMalaise
Registered interventional trials fail to cover patient-prioritised treatments in Post-COVID condition (PCC) — Gabriel et al "The most pronounced discrepancy between research activity and patient priorities, however, concerns neither pharmacological interventions nor a specific treatment modality, but a highly relevant patient-centred outcome: PEM." Preprint | Thread
September 8, 2026 at 12:03 AM
crashmargulies.bsky.social
New Essay: New Essay: Post-Exertional Neuroimmune Exhaustion and Living Below the Spoon Theory

Read the whole thing here: crashmargulies.dreamwidth.org/35286.html

Or this thread for a preview: 🧵

#PEM #PENE #pwME #MyalgicE #LongCOVID #MEcfs #PostExertionalMalaise
September 7, 2026 at 6:59 PM
tomkindlon.bsky.social
eNOS Uncoupling, Shear-Stress Tolerance, and the Two-Threshold Model of Post-Exertional Malaise in Long COVID

onlinelibrary.wiley.com/doi/10.1111/...

Discussion where lead author takes part:
s4me.info/threads/shea...

Screenshot from Science for ME update

#LongCovid #PostExertionalMalaise #PEM
eNOS Uncoupling, Shear-Stress Tolerance, and the Two-Threshold Model of Post-Exertional Malaise in Long COVID: A Mechanistic Hypothesis With Implications for Physiotherapy and Recovery Protocols — Karipidis and Karipidis Hypothesis. "Within the proposed framework, PEM severity may depend not only on the initiating exertional load, but also on the biochemical and hemodynamic environment during the subsequent 24–48 h recovery period." Article | Thread
September 5, 2026 at 12:47 PM
crashmargulies.bsky.social
New blog: Math is hard, PEM is harder.
crashmargulies.dreamwidth.org/34488.html

#PostExertionalMalaise #pwME #MEcfs #MyalgicE
September 3, 2026 at 8:05 AM
tomkindlon.bsky.social
10/
“Whilst every individual’s experience is unique, it is striking how many shared themes emerge across the PEM survey responses."

#PostExertionalMalaise #PwME #PEM #MEcfs #CFS
August 30, 2026 at 9:22 PM
benking01.bsky.social
Total movement time today:
2 hours and 7 minutes.

Of which 'Moderately' just 25 minutes - and I allow myself 60 minutes of Moderate movement per day.

I managed to Rest today, despite the odds 🙏

Successfully #Pacing to avoid the #PostExertionalMalaise #PEM associated with my #LongCovid
KiActiv movement graphs for today via my smartwatch
August 30, 2026 at 6:05 PM
thewestonmale.bsky.social
@drelke.bsky.social
@meassociation.org.uk
So important for this lesson to be learned early. thanks, Dr Hausmann!
#mecfs #me/cfs #MyalgicEncephalomyelitis #postexertionalmalaise #PEM #pacing #selfregulation
drelke.bsky.social Elke Hausmann @drelke.bsky.social · Aug 30
On a survey from Norway that highlights why it is so important for people (particular young people and children) with #ME to be given a diagnosis and to learn about PEM and pacing.

EVERYBODY should know about PEM, so they understand before it happens to them, or when it happens to others.
longcovidanswers.bsky.social Long Covid The Answers @longcovidanswers.bsky.social · Aug 30
8 Years to an #MECFS Diagnosis.
Trude Schei of the Norwegian ME Association shares findings from a 2024 survey of 3,000+ people, including 500+ who became ill before 18.

Average time to diagnosis: 8 years.

Earlier recognition could mean earlier support.
#PAIS #longcovid
August 30, 2026 at 11:32 AM
tomkindlon.bsky.social
. @actionforme.bsky.social 's PRIME webinar on Post-exertional malaise (PEM) is now available

www.youtube.com/watch?v=Ad2R...

s4me.info/threads/fact...

Screenshot from @s4me.info update

#MEcfs #LongCovid #PwME #PostExertionalMalaise #PEM @profmarkfaghy.bsky.social @sunsopeningband.bsky.social
Action for ME PRIME webinar on Post-exertional malaise (PEM) is now available on YouTube. It starts with an excellent presentation by Maree Candish based on the forum's PEM fact sheet. Other presentations are by Marjon Wormgoor and professors Faghy, Davenport and Hanson. Video | Fact Sheet | Thread
August 27, 2026 at 12:03 PM
benking01.bsky.social
Oh yes, I just worked out the third time when I overexerted: it was the first few days based in Kingswear, when I again got overexcited 🤦

How can I avoid doing this?

#Pacing to avoid #overexertion and #PostExertionalMalaise #PEM

bsky.app/profile/benk...
benking01.bsky.social Dr Ben King 🌍 @benking01.bsky.social · Aug 10
Sure enough, I pushed SLIGHTLY too much as I explored the neighbourhood here in Kingswear on Sunday evening...

But my three HRV apps are doing their thing and WARNING me, before I descend into a #PEM crash 🙏

The #ParasympatheticSwing is my friend; I will explain how...

#LongCovid
August 25, 2026 at 12:34 PM
benking01.bsky.social
A glorious 4km walked, over the course of 3 hours. Averaging just over 1km per hour 😄

#PauliPauli #SlowlySlowly

#Pacing to avoid overexertion and the debilitating #PostExertionalMalaise #PEM associated with my #LongCovid

www.instagram.com/reel/DcGoVXT...
Instagram
Create an account or log in to Instagram - Share what you're into with the people who get you.
www.instagram.com
August 16, 2026 at 2:12 PM
benking01.bsky.social
Good News!

The full Webinar has now been uploaded to YouTube.

Please share!

'How To Manage And Treat Post Exertional Malaise (PEM)

youtu.be/Na5znc92ylY?...

#LongCovid #PostExertionalMalaise #PEM #MECFS #PostViralIllness #Webinar @putrinolab.bsky.social
How to Manage and Treat Post-Exertional Malaise (PEM)
YouTube video by RTHM Health
youtu.be
August 8, 2026 at 6:28 AM
longcovidanswers.bsky.social
Post-exertional malaise (PEM)

Prof. Rob Wüst explains what PEM is, why it happens, and why pushing through can leave you feeling worse.

#LongCOVID #LongHauler #MECFS #PostExertionalMalaise #Fatigue #Mitochondria #ChronicIllness #ScienceExplained
August 7, 2026 at 4:03 PM
benking01.bsky.social
It's so clear that I have a problem with my mitochondria. But it's complicated...

Oxygen supply problems from my blood supply and problems with waste accumulation (including lactic acid) in my body. Generation of reactive oxygen species...

#LongCovid #PEM #PostExertionalMalaise
August 6, 2026 at 9:37 PM
longcovidanswers.bsky.social
Long Covid & ME/CFS Fatigue - Could Ducks and Chickens hold the hidden answer?
 Professor Rob Wüst explains muscle necrosis and mitochondria relevance in Post Exertional Malaise.
longcovidtheanswers.com/rob-wust-mar...

#longcovid #longhauler #postexertionalmalaise #pem #fatigue #mecfs
August 6, 2026 at 3:58 PM
benking01.bsky.social
I can't do much less than this 😄

Fractions of a single #VisibleHealth PacePoint used so far today!

#Resting to reduce my chances of #PostExertionalMalaise #PEM symptoms

#LongCovid
Visible screen shot. 0.7 out of 22 pace points
August 3, 2026 at 2:51 PM
benking01.bsky.social
Feeling mild #fatigue this evening. Only the second time in a whole year that I have overexerted.

Muscle weakness, muscle aches and muscle twitches too.

All thankfully mild. And because I've rested so much today and yesterday, hopefully this #PostExertionalMalaise has peaked 🙏

#LongCovid #PEM
July 18, 2026 at 7:45 PM
tomkindlon.bsky.social
Press Release Date 05-05-2026

"Australian Leaders Issue Joint Statement on ME/CFS and PEM"

natlawreview.com/press-releas...

2 months late as I am behind with some reading

#MEcfs #LongCovid #PostExertionalMalaise #PEM
Australian Leaders Issue Joint Statement on ME/CFS and PEM Press Release Date 05-05-2026 More than 20 doctors, researchers, and community leaders have signed a formal communique during ME/CFS Awareness Week (May 11-17) MELBOURNE, VICTORIA, AUSTRALIA, May 5, 2026 /EINPresswire.com/ -- More than 20 clinicians, researchers, and community leaders have signed a formal communique calling for urgent action on post-exertional malaise (PEM) in ME/CFS and long COVID. Released by Emerge Australia during ME/CFS Awareness Week (May 11-17), the statement is direct: ”Fatigue is not the same as post-exertional malaise (PEM)." Signatories include Emeritus Professor Paul Fisher (La Trobe University), Emeritus Professor Lawrence Cram AM (Australian National University), Professor David Putrino (Icahn School of Medicine, Mount Sinai), Dr Bernard Shiu (Geelong Long COVID Clinic), Adjunct Professor Sophie Scott OAM and Tracey Spicer AM. PEM is a clinically significant worsening of symptoms after physical, cognitive, emotional, or orthostatic activity. It can cause serious symptom exacerbation, functional decline, and lasting health deterioration. When PEM is missed, patients may receive advice that worsens their condition and causes avoidable harm. The communique calls on healthcare providers, educators, employers, and policymakers to adopt PEM-aware approaches to care.
July 3, 2026 at 12:54 AM
achronicvoice.com
" #PostExertionalMalaise ( #PEM ) is not tiredness. It’s not even #exhaustion. It’s a systemic crash that occurs after physical, #cognitive, or emotional exertion that exceeds your body’s brutally reduced energy envelope.": buff.ly/DfyBmTL

by @darthfoo.bsky.social
#MECFS #pwME #ChronicFatigue
Why I Can’t Just Meet You for Dinner
The Reality of Post-Exertional Malaise
buff.ly
June 29, 2026 at 8:30 AM
meactmaryland.bsky.social
Q & A Quote of the day
~Saturday 6/27/26~

1/2

“We still need more knowledge about what PEM entails… Our general impression is that if we can get at the main physiological abnormality in each patient — usually that’s the orthostatic intolerance — ..."
-Rowe

#NEISVoid #pwME #PostExertionalMalaise
“We still need more knowledge about what PEM entails… Our general impression is that if we can get at the main physiological abnormality in each patient — usually that’s the orthostatic intolerance — if we can treat that effectively, people then can increase their activity without generating PEM.” --Dr. Peter Rowe Q & Capstone Episode Evidence-Based Pediatric ME/CFS Webinar Series youtube.com/@MEActMaryland blue & yellow background with geometric designs #MEAction Maryland logo ~Q & A Capstone interview with Dr. Peter Rowe airing Monday 6/29!~
June 27, 2026 at 10:22 PM
tomkindlon.bsky.social
I have just watched this and thought it was good.
#MEcfs #LongCovid #PostExertionalMalaise #PEM
emergeaustralia.bsky.social Emerge Australia @emergeaustralia.bsky.social · May 15
Recognising #PEM early in your patients is critical for safe and #MECFS informed care.

PEM can be hidden - patients may appear well during appointments but experience significant deterioration afterwards.

You can learn more about PEM and #pacing - zurl.co/nnY1W
Promotional graphic for Emerge Australia’s ME/CFS Awareness Week "Top 10 PEM tips". Soft blue background with text in a white box and a screen shot of tip 1. "STOP! It might be PEM" at an angle. Text: Post-exertional malaise (PEM) is not the same as fatigue. Recognising it early in your patients is critical for safe and ME/CFS informed care. Watch our short, ten minute talk aimed at health professionals to recognise and understand PEM. Emerge Australia logo is in the top left corner.
June 27, 2026 at 12:41 AM
tomkindlon.bsky.social
Communiqué: Fatigue isn't the same as post-exertional malaise (PEM)

"PEM is real. It is serious. And it must not be made worse by misunderstanding."

Signed by researchers, clinicians and advocates.

emerge.org.au/wp-content/u...

#MEcfs #LongCovid #PostExertionalMalaise #PEM
Communiqué We, the undersigned clinicians, researchers and community leaders, call for urgent action to improve recognition of post-exertional malaise (PEM) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), long COVID and its impact on related energy-limiting chronic conditions. PEM is not ordinary fatigue. It is a clinically significant worsening of symptoms after physical, cognitive, emotional or orthostatic activity, and can result in serious symptom exacerbation, functional decline and, for some, lasting loss of health and quality of life capacity. When PEM is missed or misunderstood, patients may be given advice or subjected to expectations that worsen their condition, their multimorbidity, and cause avoidable harm. Earlier recognition of PEM is essential for safer care and better outcomes, limiting or slowing the impacts of ME/CFS and long COVID. Approaches must be evidence-informed, individualised, and responsive to the fluctuating nature of these conditions. We call on healthcare providers, educators, employers and policymakers to adopt PEM-aware approaches that reflect the reality and risks associated with PEM. PEM is real. It is serious. And it must not be made worse by misunderstanding. Sincerely,
June 26, 2026 at 10:47 PM