#PIF1
Sipping
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January 8, 2024 at 2:06 AM
I am happy to share our latest paper on human PIF1, a wonderful collaboration with Raphael Guerois, Ralf Seidel and Ulrich Rass and their teams. Human PIF1 is quite different from its yeast counterpart. Congratulations to Akshay Jayachandran, the first author.

genesdev.cshlp.org/content/earl...
Human PIF1 clears secondary DNA structures by coupled DNA unwinding and rewinding activities
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
genesdev.cshlp.org
August 14, 2026 at 9:15 AM
Beautiful paper by Akshay Jayachandran @cejkalab.bsky.social and co-workers delineating the functional divergence of yeast and human PIF1. It was a pleasure making a small contribution to the study @gdsc-sussex.bsky.social @sussex.ac.uk! www.genesdev.org/cgi/doi/10.1....
August 11, 2026 at 1:48 PM
Pokemon Infinite Fusion Hoenn's first demo is out NOW! 🧬
Features:
- First 2 gyms available
- Tranfer Pokemon from PIF1 to PIFH and vice versa
- PokeNav and PokeRadar
- Dynamic Weather
- Overworld encounters
- Trainer rematches
- More

⏬ Check it out ⏬
www.reddit.com/r/PokemonInf...
June 14, 2026 at 11:28 AM
NEW PAPER: Human PIF1 clears secondary DNA structures by coupled DNA unwinding and rewinding activities — with contributions from Jessica Hudson and Ulrich Rass at the GDSC. genesdev.cshlp.org/content/earl...
August 13, 2026 at 12:50 PM
Light interacts with mechanical stress to regulate the seed-to-seedling transition

Yun Meng, Jiashuai Wu … Shameen Sajid, Qingqing Wu

link.springer.com/article/10.1...

#Crops #PIF1 #LightDevelopment #SoilDepth
Light interacts with mechanical stress to regulate the seed-to-seedling transition - Stress Biology
The transition from seed to seedling represents a critical developmental phase that determines seedling survival, crop establishment, and yield potential. This intricate developmental process encompas...
link.springer.com
January 19, 2026 at 2:05 PM
🌱 RESEARCH 🌱

HFR1 regulates chlorophyll biosynthesis and protochlorophyllide accumulation partly through PIFs during the de-etiolation process, thereby influencing singlet oxygen production and resultant photo-oxidative bleaching - Chaturvedi et al.

🔗 doi.org/10.1093/jxb/...

#PlantScience 🧪
October 19, 2025 at 11:19 AM
Check out a novel method for studying Phase 2 meiotic recombination in #buddingyeast that uncovers interactions between RAD54, TID1, and PIF1.

Read more in #GENETICS about how this assay can be applied to other recombination genes to understand double-stranded break repair. 

🔗 buff.ly/mY5XxxX
July 29, 2026 at 8:02 PM
PP4Psy2 regulates Rrm3 and Pif1 helicases to facilitate DSB resection across tandem retrotransposons https://www.biorxiv.org/content/10.1101/2025.02.19.639064v1
February 26, 2025 at 9:17 PM
Dissecting the role of PCNA and Pif1 in replication of individual DNA molecules by DNA polymerase δ. https://www.biorxiv.org/content/10.64898/2026.05.19.725978v1
May 21, 2026 at 6:46 PM
PIF1, RAD54 and RDH54/TID1 promote residual double strand break repair during meiosis in the budding yeast, Saccharomyces cerevisiae https://www.biorxiv.org/content/10.64898/2026.01.05.697805v1
January 6, 2026 at 10:31 AM
You didn’t make it up! I first heard it in school and am resolved to use it more now you’ve reminded me of it.
www.worldwidewords.org/qa/qa-pif1.htm
Piffy on a rock bun
Where does the northern English expression <em>Piffy on a rock bun</em> come from?
www.worldwidewords.org
January 3, 2025 at 7:41 PM
Started Pokemon: Infinite Fusion Hoenn and my god it’s so good to be back. They have added so many more sprites since PIF1 and even though the game is in beta and you can only do up to the third gym, there’s so many possibilities already. This is my team so far!
July 21, 2026 at 1:21 PM
The function of human PIF1 in G quadruplex formation and replication stress response at ALT telomeres https://www.biorxiv.org/content/10.64898/2026.08.31.748286v1
September 2, 2026 at 2:17 AM
The function of human PIF1 in G quadruplex formation and replication stress response at ALT telomeres https://www.biorxiv.org/content/10.64898/2026.08.31.748286v1
September 2, 2026 at 2:17 AM
The phytochrome-interacting factor genes PIF1 and PIF4 are functionally diversified due to divergence of promoters and proteins

academic.oup.com/plcell/advan...
#plantscience
April 10, 2024 at 1:40 PM
Pif1 promotes DNA synthesis during homologous recombination. @NatureNews http://goo.gl/mLcEQx
Browse Articles | Nature
Browse the archive of articles on Nature
goo.gl
November 24, 2024 at 5:47 AM
2 new papers @NatureMagazine demonstrate a function of Pif1 helicase in break-induced replication. http://goo.gl/9N9rVi
Goo.gl is sunsetting
goo.gl
November 24, 2024 at 5:33 AM
Using in vitro reconsituted plasmid replication, Pif1 and Rrm3, but not Sgs1-Top3 or Top2, promote completion of Eukaryote DNA replication by assisting replication fork convergence @MolecularCell
https://xfe88.app.goo.gl/Pif1
November 23, 2024 at 4:04 PM
Alternative translation initiation by ribosomal leaky scanning produces multiple isoforms of the Pif1 helicase https://www.biorxiv.org/content/10.1101/2024.01.21.576553v1
Alternative translation initiation by ribosomal leaky scanning produces multiple isoforms of the Pif1 helicase https://www.biorxiv.org/content/10.1101/2024.01.21.576553v1
In budding yeast, the integrity of both the nuclear and mitochondrial genomes relies on dual-targete
www.biorxiv.org
January 23, 2024 at 1:28 PM
Dissecting the role of PCNA and Pif1 in replication of individual DNA molecules by DNA polymerase δ. https://www.biorxiv.org/content/10.64898/2026.05.19.725978v1
May 21, 2026 at 6:46 PM
PIF1, RAD54 and RDH54/TID1 promote residual double strand break repair during meiosis in the budding yeast, Saccharomyces cerevisiae https://www.biorxiv.org/content/10.64898/2026.01.05.697805v1
January 6, 2026 at 10:31 AM
PP4Psy2 regulates Rrm3 and Pif1 helicases to facilitate DSB resection across tandem retrotransposons https://www.biorxiv.org/content/10.1101/2025.02.19.639064v1
February 26, 2025 at 9:17 PM