Glad to have joined Bluesky yesterday! Great to have followed so many old and new friends/colleagues. Looking forward to all the great RNA biology and fun science chats!
#RNA #RNASky
P.S. Are there any Starter Packs for model organisms, especially, #BuddingYeast #Scerevisiae?
#RNA #RNASky
P.S. Are there any Starter Packs for model organisms, especially, #BuddingYeast #Scerevisiae?
November 25, 2024 at 12:16 AM
Glad to have joined Bluesky yesterday! Great to have followed so many old and new friends/colleagues. Looking forward to all the great RNA biology and fun science chats!
#RNA #RNASky
P.S. Are there any Starter Packs for model organisms, especially, #BuddingYeast #Scerevisiae?
#RNA #RNASky
P.S. Are there any Starter Packs for model organisms, especially, #BuddingYeast #Scerevisiae?
Nice! Excellent tools for #yeast #genomeengineering!
#CRISPR #Cas9 #Retron #Plasmid #Scerevisiae #buddingyeast
#CRISPR #Cas9 #Retron #Plasmid #Scerevisiae #buddingyeast
December 8, 2024 at 1:54 PM
Nice! Excellent tools for #yeast #genomeengineering!
#CRISPR #Cas9 #Retron #Plasmid #Scerevisiae #buddingyeast
#CRISPR #Cas9 #Retron #Plasmid #Scerevisiae #buddingyeast
a short and sweet paper in which we use 3D STED and Micro-C analysis to show dramatic changes in large 3D chromatin structures in quiescence. www.biorxiv.org/content/10.1...
Sir2 is required for the quiescence-specific condensed three-dimensional chromatin structure of rDNA
Quiescence in Saccharomyces cerevisiae is a reversible G0 crucial for long-term survival under nutrient-deprived conditions. During quiescence, the genome is hypoacetylated and chromatin undergoes sig...
www.biorxiv.org
December 13, 2024 at 5:30 PM
#dsRNA #BuddingYeast
Pervasive formation of double-stranded RNAs by overlapping sense/antisense transcripts in budding yeast mitosis and meiosis
Szachnowski et al.
m.rnajournal.cshlp.org/content/earl...
Pervasive formation of double-stranded RNAs by overlapping sense/antisense transcripts in budding yeast mitosis and meiosis
Szachnowski et al.
m.rnajournal.cshlp.org/content/earl...
RNA | Mobile
m.rnajournal.cshlp.org
January 25, 2025 at 5:30 PM
#dsRNA #BuddingYeast
Pervasive formation of double-stranded RNAs by overlapping sense/antisense transcripts in budding yeast mitosis and meiosis
Szachnowski et al.
m.rnajournal.cshlp.org/content/earl...
Pervasive formation of double-stranded RNAs by overlapping sense/antisense transcripts in budding yeast mitosis and meiosis
Szachnowski et al.
m.rnajournal.cshlp.org/content/earl...
A tail of two Nab2’s….
Very interesting! Congrats!
#Nab2 #PolyATail #Length #BuddingYeast #Scerevisiae
#RNA
www.biorxiv.org/content/10.1...
Very interesting! Congrats!
#Nab2 #PolyATail #Length #BuddingYeast #Scerevisiae
#RNA
www.biorxiv.org/content/10.1...
A kinetic ruler controls mRNA poly(A) tail length
Poly(A) tails of newly synthesized mRNAs have uniform lengths, arising through cooperation between the cleavage and polyadenylation complex (CPAC) and poly(A) binding proteins (PABPs). In the budding ...
www.biorxiv.org
May 3, 2025 at 11:34 AM
A tail of two Nab2’s….
Very interesting! Congrats!
#Nab2 #PolyATail #Length #BuddingYeast #Scerevisiae
#RNA
www.biorxiv.org/content/10.1...
Very interesting! Congrats!
#Nab2 #PolyATail #Length #BuddingYeast #Scerevisiae
#RNA
www.biorxiv.org/content/10.1...
Cool! Congrats!
#tRNA #Intron #fitRNA #BuddingYeast
Free introns of tRNAs as complementarity-dependent regulators of gene expression: Molecular Cell www.cell.com/molecular-ce...
#tRNA #Intron #fitRNA #BuddingYeast
Free introns of tRNAs as complementarity-dependent regulators of gene expression: Molecular Cell www.cell.com/molecular-ce...
Free introns of tRNAs as complementarity-dependent regulators of gene expression
Nostramo et al. demonstrate that free introns of tRNAs (fitRNAs) are a previously
unknown class of small noncoding regulatory RNAs that bind to complementary sequences
on mRNA ORFs, leading to decay. ...
www.cell.com
February 12, 2025 at 5:05 AM
Cool! Congrats!
#tRNA #Intron #fitRNA #BuddingYeast
Free introns of tRNAs as complementarity-dependent regulators of gene expression: Molecular Cell www.cell.com/molecular-ce...
#tRNA #Intron #fitRNA #BuddingYeast
Free introns of tRNAs as complementarity-dependent regulators of gene expression: Molecular Cell www.cell.com/molecular-ce...
Growth rate regulates RNA polymerase II transcription elongation in Saccharomyces cerevisiae https://www.biorxiv.org/content/10.1101/2024.11.26.625403v1
Growth rate regulates RNA polymerase II transcription elongation in Saccharomyces cerevisiae https://www.biorxiv.org/content/10.1101/2024.11.26.625403v1
Cells must adapt to changing environmental conditions to maintain their fitness and to compete with
www.biorxiv.org
November 28, 2024 at 3:28 PM
Cool!
#Mex67 #Nuclear #mRNAExport #mRNA #Nab2 #Yra1 #Hpr1 #mRNP #BuddingYeast #RNA
www.biorxiv.org/content/10.1...
#Mex67 #Nuclear #mRNAExport #mRNA #Nab2 #Yra1 #Hpr1 #mRNP #BuddingYeast #RNA
www.biorxiv.org/content/10.1...
An elevated level of the mRNA exporter Mex67-Mtr2 in nuclear mRNPs impairs nuclear mRNA export
In eukaryotes, a crucial step in gene expression is the export of the mRNA out of nucleus. The conserved mRNA exporter Mex67-Mtr2 (NXF1-NXT1 in human) is a key factor in this process. In S. cerevisiae...
www.biorxiv.org
March 3, 2025 at 4:59 PM
Overview of the Saccharomyces cerevisiae population structure through the lens of 3,034 genomes
doi.org/10.1093/g3jo...
doi.org/10.1093/g3jo...
Overview of the Saccharomyces cerevisiae population structure through the lens of 3,034 genomes
Abstract. With the rise of high-throughput sequencing technologies, a holistic view of genetic variation within populations—through population genomics stu
doi.org
December 12, 2024 at 4:56 PM
#RNAExosome #Rrp6 #RNAProcessing #Splicing #UPR #UnfoldedProteinResponse #BuddingYeast
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
RNA exosome-driven RNA processing instructs the duration of the unfolded protein response
Abstract. Upon stresses, cellular compartments initiate adaptive programs meant to restore homeostasis. Dedicated to the resolution of transient perturbati
academic.oup.com
March 4, 2025 at 8:24 PM
New research in #GENETICS provides in vivo evidence of the interaction between Scm3 and N-Cse4, two proteins critical for kinetochore formation at centromeres in #buddingyeast.
🔗 buff.ly/109WHyQ
🔗 buff.ly/109WHyQ
August 17, 2026 at 8:01 PM
New research in #GENETICS provides in vivo evidence of the interaction between Scm3 and N-Cse4, two proteins critical for kinetochore formation at centromeres in #buddingyeast.
🔗 buff.ly/109WHyQ
🔗 buff.ly/109WHyQ
Just heard a great seminar from Guillaume Chanfreau discussing this work! @guillaumechanfreau.bsky.social
#TranscriptionTermination #Splicing #Efficiency #RNA #3'endProcessing #Scerevisiae #BuddingYeast
www.biorxiv.org/content/10.1...
#TranscriptionTermination #Splicing #Efficiency #RNA #3'endProcessing #Scerevisiae #BuddingYeast
www.biorxiv.org/content/10.1...
Transcription termination promotes splicing efficiency and fidelity in a compact genome
Splicing of terminal introns is coupled to 3′-end processing by cleavage and polyadenylation (CPA) of mRNAs in mammalian genes. Whether this functional coupling is universally conserved across eukaryo...
www.biorxiv.org
April 17, 2025 at 6:34 PM
Just heard a great seminar from Guillaume Chanfreau discussing this work! @guillaumechanfreau.bsky.social
#TranscriptionTermination #Splicing #Efficiency #RNA #3'endProcessing #Scerevisiae #BuddingYeast
www.biorxiv.org/content/10.1...
#TranscriptionTermination #Splicing #Efficiency #RNA #3'endProcessing #Scerevisiae #BuddingYeast
www.biorxiv.org/content/10.1...
Check out a novel method for studying Phase 2 meiotic recombination in #buddingyeast that uncovers interactions between RAD54, TID1, and PIF1.
Read more in #GENETICS about how this assay can be applied to other recombination genes to understand double-stranded break repair.
🔗 buff.ly/mY5XxxX
Read more in #GENETICS about how this assay can be applied to other recombination genes to understand double-stranded break repair.
🔗 buff.ly/mY5XxxX
July 29, 2026 at 8:02 PM
Check out a novel method for studying Phase 2 meiotic recombination in #buddingyeast that uncovers interactions between RAD54, TID1, and PIF1.
Read more in #GENETICS about how this assay can be applied to other recombination genes to understand double-stranded break repair.
🔗 buff.ly/mY5XxxX
Read more in #GENETICS about how this assay can be applied to other recombination genes to understand double-stranded break repair.
🔗 buff.ly/mY5XxxX
Nice! #RNAExosome #Localization #BuddingYeast
New Insights into #nuclear #import and #nucleolar #localization of yeast #RNA #exosome #subunits
Valdir Gomes Neto...Carla C. Oliveira
www.biorxiv.org/content/10.1...
New Insights into #nuclear #import and #nucleolar #localization of yeast #RNA #exosome #subunits
Valdir Gomes Neto...Carla C. Oliveira
www.biorxiv.org/content/10.1...
New Insights into nuclear import and nucleolar localization of yeast RNA exosome subunits
The RNA exosome is a multiprotein complex essential for RNA maturation and degradation. In budding yeast, a nine-subunit protein complex (Exo9) associated with Rrp44 forms Exo10 in the cytoplasm and, ...
www.biorxiv.org
March 11, 2025 at 3:28 PM
Nice! #RNAExosome #Localization #BuddingYeast
New Insights into #nuclear #import and #nucleolar #localization of yeast #RNA #exosome #subunits
Valdir Gomes Neto...Carla C. Oliveira
www.biorxiv.org/content/10.1...
New Insights into #nuclear #import and #nucleolar #localization of yeast #RNA #exosome #subunits
Valdir Gomes Neto...Carla C. Oliveira
www.biorxiv.org/content/10.1...
Cool!
#Metabolism #Reprogramming #Energy #Stress #NTP #Helicase #Translation #BuddingYeast
www.biorxiv.org/content/10.1...
#Metabolism #Reprogramming #Energy #Stress #NTP #Helicase #Translation #BuddingYeast
www.biorxiv.org/content/10.1...
Metabolic tuning enables immediate adaptation to energy stress in yeast
In Saccharomyces cerevisiae , glucose depletion induces metabolic reprogramming through widespread transcriptional and translational reorganization. We report that initial, very rapid translational si...
www.biorxiv.org
June 11, 2025 at 4:57 PM
