#Plasmatocytes
LightNews LightNews
bilderlab.bsky.social
Anti-Hemese staining of plasmatocytes —essentially #Drosophila macrophages. Dm 1.2/1. Image by Yoshiki Sakai in the lab. (4/5)
February 25, 2025 at 7:25 PM
dev-journal.bsky.social
ROS heal the cricket leg

This Research Highlight showcases the work from Misa Okumura-Hirono, Tetsuya Bando and colleagues
journals.biologists.com/dev/article/...
Wound healing, cell proliferation and gene expression in third instar nymphs at 2 dpa. (A) Image of a two-spotted cricket Gryllus bimaculatus third-instar nymph and diagram of the leg, showing the site of amputation. The leg of the cricket is divided into six parts: coxa, trochanter, femur, tibia, tarsus and claw. To induce leg regeneration, we amputated the tibia. (B) H-E-stained sections of PBS-lipo- and Clo-lipo-treated regenerating legs at 2 dpa. Plasmatocytes were visualised by India ink incorporation. cu, cuticle; epi, epidermis; mu, muscle; so, subgenual organ; tr, trachea; we, wound epidermis. Images are representative of ten samples. (C) Fluorescence microscopy images of the EdU incorporation assay in PBS-lipo- and Clo-lipo-treated regenerating legs at 2 dpa. EdU-incorporating S-phase nuclei are shown in magenta and all nuclei (stained with Hoechst 33342) are shown in blue. Scale bars: 200 µm (B,C). (D) The ratios of proliferating cell nuclei of PBS-lipo- and Clo-lipo-treated regenerating legs are shown in box plots. ***P<0.001 (unpaired, two-tailed Student's t-test between PBS-lipo- and Clo-lipo-treated regenerating legs). n=4. (E) Schematic of Gryllus Duox and Nox5 proteins. Double-headed arrows and red lines indicate regions for dsRNA and qPCR amplicons, respectively. (F) Relative expression levels of Duox and Nox5 transcripts in PBS-lipo- and Clo-lipo-treated regenerating legs at 2 dpa, as revealed by qPCR. The y-axis indicates normalised expression after PBS-lipo-treatment and relative expression levels after Clo-lipo-treatment. ***P<0.001 (unpaired, two-tailed Student's t-test between PBS-lipo- and Clo-lipo-treated regenerating legs); n.s., not significant. n=8.
November 28, 2025 at 7:43 PM
veraksa.bsky.social
A comparison of #Drosophila plasmatocytes with vertebrate blood cells reveals similarities with myeloid cell lineages in zebrafish, mouse, and human.
doi.org/10.1371/jour...
Molecular traces of Drosophila hemocytes reveal transcriptomic conservation with vertebrate myeloid ...
Author summary The immune system protects organisms from invaders and has been conserved throughout animal evolution. Hemocytes are blood cells in Drosophila that are known to have similar functions t...
doi.org
December 30, 2023 at 7:04 PM
bilderlab.bsky.social
Anti-NimC1 staining of plasmatocytes —essentially #Drosophila macrophages. Combination of Dm N1/9 and Dm N47/7. Image by Yoshiki Sakai in the lab. (3/5)
February 25, 2025 at 7:25 PM
limes-bonn.bsky.social
Developmental #programming by #maternal #obesity alters offspring #lifespan and immune responses in a diet- and sex-specific manner. #Cells&Development @masslab.bsky.social #HasenauerLab #ThieleLab #BauerLab @unibonn.bsky.social #Hemocytes; #Macrophages; #Metabolism; #Plasmatocytes. rb.gy/pe6d15
Developmental programming by maternal obesity alters offspring lifespan and immune responses in a diet- and sex-specific manner
Maternal obesity is a growing health concern that predisposes offspring to metabolic dysfunction, immune system alterations, and neurodegenerative dis…
rb.gy
July 14, 2025 at 6:59 AM
rridrobot.bsky.social
The authors included RRIDs in their EMBO Reports paper! Thanks for making your methods matter! #STMpublishing #RRID #RRID
Transdifferentiation of plasmatocytes to crystal cells in the lymph gland of Drosophila melanogaster
doi.org
May 18, 2025 at 7:00 AM
windfelder.bsky.social
On Friday (12:00 – 13:00 CET), two incredibly talented researchers will present their work, and I have the honor of collaborating with them:
🔹 Hannah Vogt (right): Imaging of plasmatocytes in M. sexta larvae using light sheet microscopy (IMMU-036)
March 13, 2025 at 5:24 PM
geneticjonathan.bsky.social
To any #Drosophila scientist: Did you know the famous S2 cells may be a useful hematopoiesis model? Just published our efforts towards transdifferentiating plasmatocyte-like S2 cells into lamellocyte-like cells.

Great collaboration with @bogdanlab.bsky.social!

www.sciencedirect.com/science/arti...
Targeted degradation of Drosophila FOG homolog U-shaped mimics macrophage transdifferentiation in S2 cells
The highly plastic cellular component of the Drosophila immune system consists of three main blood cell types - plasmatocytes, crystal cells and lamel…
www.sciencedirect.com
April 23, 2026 at 11:25 AM
fly-broadcast.bsky.social
A high throughput method for isolation of plasmatocytes from hemolymph of adult Drosophila
#Drosophila
A high throughput method for isolation of plasmatocytes from hemolymph of adult Drosophila #Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
May 14, 2025 at 11:23 PM
fly-broadcast.bsky.social
Transdifferentiation of plasmatocytes to crystal cells in the lymph gland of Drosophila melanogaster
#Drosophila
Transdifferentiation of plasmatocytes to crystal cells in the lymph gland of Drosophila melanogaster #Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
March 13, 2025 at 10:23 AM
biorxiv-devbio.bsky.social
Macrophage subpopulation identity in Drosophila is modulated by apoptotic cell clearance and related signalling pathways https://www.biorxiv.org/content/10.1101/2023.09.14.557767v1
Macrophage subpopulation identity in Drosophila is modulated by apoptotic cell clearance and related signalling pathways https://www.biorxiv.org/content/10.1101/2023.09.14.557767v1
In Drosophila blood, plasmatocytes of the haemocyte lineage represent the functional equivalent of v
www.biorxiv.org
September 15, 2023 at 12:31 AM
biorxivpreprint.bsky.social
Macrophage subpopulation identity in Drosophila is modulated by apoptotic cell clearance and related signalling pathways https://www.biorxiv.org/content/10.1101/2023.09.14.557767v1
Macrophage subpopulation identity in Drosophila is modulated by apoptotic cell clearance and related signalling pathways https://www.biorxiv.org/content/10.1101/2023.09.14.557767v1
In Drosophila blood, plasmatocytes of the haemocyte lineage represent the functional equivalent of v
www.biorxiv.org
September 15, 2023 at 12:31 AM
interactivefly.bsky.social
Marcetteau, J., Duarte, P., Leitao, A. B., Sucena, E. (2025). Transdifferentiation of plasmatocytes to crystal cells in the lymph gland of Drosophila melanogaster EMBO Rep, 26(8):2077-2097 link.springer.com/article/10.1...
Transdifferentiation of plasmatocytes to crystal cells in the lymph gland of Drosophila melanogaster - EMBO Reports
Under homeostatic conditions, haematopoiesis in Drosophila larvae occurs in the lymph gland and sessile haemocyte clusters to produce two functionally and morphologically different cells: plasmatocyte...
link.springer.com
April 1, 2026 at 6:35 PM