Congrats to our PIs @masslab.bsky.social & #HasenauerLab on their latest work uncovering the crosstalk between #Kupffer #Cells and #Hepatocytes in the context of maternal obesity.
A great example of macrophage-driven communication shaping tissue physiology
👇 #Macrophages #Liver #Crosstalk
A great example of macrophage-driven communication shaping tissue physiology
👇 #Macrophages #Liver #Crosstalk
We are SO EXCITED to share our story @nature.com:
🧵1/
Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring.
This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease.
👉 Read here: rdcu.be/erD3b
🧵1/
Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring.
This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease.
👉 Read here: rdcu.be/erD3b
Kupffer cell programming by maternal obesity triggers fatty liver disease
Nature - In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.
rdcu.be
June 19, 2025 at 12:41 PM
Congrats to our PIs @masslab.bsky.social & #HasenauerLab on their latest work uncovering the crosstalk between #Kupffer #Cells and #Hepatocytes in the context of maternal obesity.
A great example of macrophage-driven communication shaping tissue physiology
👇 #Macrophages #Liver #Crosstalk
A great example of macrophage-driven communication shaping tissue physiology
👇 #Macrophages #Liver #Crosstalk
Integrative #modeling of the spread of serious #infectious #diseases and corresponding #wastewater dynamics; #Epidemics #HasenauerLab @unibonn.bsky.social; #Agent-based model; #Hydrodynamic model shorturl.at/M9iqS
Integrative modeling of the spread of serious infectious diseases and corresponding wastewater dynamics
The COVID-19 pandemic has emphasized the critical need for accurate disease modeling to inform public health interventions. Traditional reliance on co…
shorturl.at
June 16, 2025 at 6:42 AM
Integrative #modeling of the spread of serious #infectious #diseases and corresponding #wastewater dynamics; #Epidemics #HasenauerLab @unibonn.bsky.social; #Agent-based model; #Hydrodynamic model shorturl.at/M9iqS
Developmental #programming by #maternal #obesity alters offspring #lifespan and immune responses in a diet- and sex-specific manner. #Cells&Development @masslab.bsky.social #HasenauerLab #ThieleLab #BauerLab @unibonn.bsky.social #Hemocytes; #Macrophages; #Metabolism; #Plasmatocytes. rb.gy/pe6d15
Developmental programming by maternal obesity alters offspring lifespan and immune responses in a diet- and sex-specific manner
Maternal obesity is a growing health concern that predisposes offspring to metabolic dysfunction, immune system alterations, and neurodegenerative dis…
rb.gy
July 14, 2025 at 6:59 AM
Developmental #programming by #maternal #obesity alters offspring #lifespan and immune responses in a diet- and sex-specific manner. #Cells&Development @masslab.bsky.social #HasenauerLab #ThieleLab #BauerLab @unibonn.bsky.social #Hemocytes; #Macrophages; #Metabolism; #Plasmatocytes. rb.gy/pe6d15
A dynamic model for #Waddington's #landscape accounting for #cell-to-cell #communication. #MathBiosci @unibonn.bsky.social #HasenauerLab #SchlitzerLab; #Dendritic #cell #activation; #Stem #cell #regeneration shorturl.at/IEMsy
A dynamic model for Waddington’s landscape accounting for cell-to-cell communication
Waddington’s landscape provides a conceptual model for developmental processes. It is the basis of various mathematical models describing cell maturat…
shorturl.at
September 26, 2025 at 6:14 AM
A dynamic model for #Waddington's #landscape accounting for #cell-to-cell #communication. #MathBiosci @unibonn.bsky.social #HasenauerLab #SchlitzerLab; #Dendritic #cell #activation; #Stem #cell #regeneration shorturl.at/IEMsy
Assessment of #uncertainty #quantification in #universal #differential #equations #PhilosTransAMathPhysEngSci #HasenauerLab @unibonn.bsky.social #scientific #machine #learning shorturl.at/UCDpU
Assessment of uncertainty quantification in universal differential equations | Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Scientific machine learning is a new class of approaches that integrate physical knowledge
and mechanistic models with data-driven techniques to uncover the governing equations
of complex processes. A...
shorturl.at
April 3, 2025 at 6:33 AM
New paper out: Coupled epidemiological and wastewater modeling at the urban scale: A case study for Munich #iScience @unibonn.bsky.social #HasenauerLab shorturl.at/BdQ3g #SARS-CoV-2; #early-warning #systems; #hydrodynamic #modeling
August 7, 2026 at 6:03 AM
New paper out: Coupled epidemiological and wastewater modeling at the urban scale: A case study for Munich #iScience @unibonn.bsky.social #HasenauerLab shorturl.at/BdQ3g #SARS-CoV-2; #early-warning #systems; #hydrodynamic #modeling
Loss formulations for assumption-free neural inference of #SDE #coefficient #functions #npj-SystemsBiologyandApplications #HasenauerLab @unibonn.bsky.social shorturl.at/hkDsB
Loss formulations for assumption-free neural inference of SDE coefficient functions - npj Systems Biology and Applications
npj Systems Biology and Applications - Loss formulations for assumption-free neural inference of SDE coefficient functions
shorturl.at
March 5, 2025 at 8:31 AM
Loss formulations for assumption-free neural inference of #SDE #coefficient #functions #npj-SystemsBiologyandApplications #HasenauerLab @unibonn.bsky.social shorturl.at/hkDsB