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science.org
In a new #ScienceSignaling study, researchers introduce extracellular #TurboID, a refinement of the popular proteomics tool that interrogates #ProteinProteinInteractions on the exterior cell membrane, and characterize interactions between #EGFR and #LDLR. scim.ag/3DgfJr9
Extracellular proximal interaction profiling by cell surface–targeted TurboID reveals LDLR as a partner of liganded EGFR
A modified form of TurboID identifies extracellular interactions between transmembrane proteins.
www.science.org
December 13, 2024 at 5:22 PM
cp-trendsbiochem.bsky.social
📝 Online now - the Review "PTMs as molecular encoders: reprogramming chaperones into epichaperomes for network control in disease" from @chiosislabmskcc.bsky.social et al.

#ProteinProteinInteractions #ProteinNetworks #ChaperoneReprogramming

Read it here 👉 authors.elsevier.com/sd/article/S...
August 28, 2025 at 1:36 PM
jsantoyo.bsky.social
Long-read sequencing to detect full-length protein–protein interactions. #LongRead #Sequencing #ProteinProteinInteractions #PPi #ScientificReports
www.nature.com/articles/s41...
July 30, 2025 at 9:15 AM
aegeanconf.bsky.social
DEADLINE REMINDER June 15th for Early Registration Fee / Abstract Submission: 8th Int'l Conference on #Molecular Perspectives in #ProteinProteinInteractions #PPI from Oct. 17-22 in #Chania #Crete www.aegeanconferences.org/src/App/conf...
May 14, 2025 at 10:34 AM
cp-trendsbiochem.bsky.social
📣 Online now - the Feature Review "Exploring non-degrading molecular glues for protein-protein interaction" from Jian Zhang, Wenchao Lu, and co.

#ProteinProteinInteractions #MolecularGlues #ChemicallyInducedProximity #DrugDiscovery

Read it here 👉 authors.elsevier.com/a/1leHv3S6Gf...
August 25, 2025 at 1:20 PM
somssich.bsky.social
📜 Using AlphaFold Multimer to discover interkingdom protein–protein interactions

🧑‍🔬 Felix Homma, Joy Lyu, Renier A. L. van der Hoorn

📔 The Plant Journal

🔗 onlinelibrary.wiley.com/doi/10.1111/...

#️⃣ #PlantScience #AlphaFold #ProteinProteinInteractions #PlantProteomics
Using AlphaFold Multimer to discover interkingdom protein–protein interactions
The prediction of structure of protein complexes with artificial intelligence is making a deep impact in plant science. Here, we share our experiences on using AlphaFold Multimer on a computing clust...
onlinelibrary.wiley.com
August 19, 2024 at 11:32 AM
mpolychronidou.bsky.social
New approach for designing proteins that bind intrinsically disordered protein regions ➡️ www.science.org/doi/10.1126/...
#IDRs #ProteinProteinInteractions
Design of intrinsically disordered region binding proteins
Intrinsically disordered proteins and peptides play key roles in biology, but a lack of defined structures and high variability in sequence and conformational preferences have made targeting such syst...
www.science.org
July 18, 2025 at 7:23 AM
csbj.org
🔗 Targeting CAPON to modulate the CAPON–NOS Axis: a computational approach. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.cs...

📚 CSBJ: www.csbj.org

#DrugDiscovery #ComputationalBiology #AlzheimersResearch #Neuroscience #ProteinProteinInteractions #VirtualScreening
Targeting CAPON to modulate the CAPON–NOS Axis: a computational approach. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.11.001
December 7, 2025 at 3:27 AM
japplcryst.iucr.org
M​adhumathi Sanjeevi et al.: MIPDS: a comprehensive database on the molecular interactions in protein dimer structures ##ProteinProteinInteractions##DimerStructures##Databases... ##IUCrhttps://journals.iucr.org/paper?S1600576724007131
MIPDS: a comprehensive database on the molecular interactions in protein dimer structures
A database has been developed that comprises protein dimeric structures and their respective interactions. This database provides valuable insights into the type of interaction, including those mediated by water or small molecules and direct interactions.
journals.iucr.org
August 20, 2024 at 12:00 AM
febsletters.bsky.social
Ligand recognition by 14-3-3 proteins: is #phosphorylation required?

➡️bit.ly/43jJLFq

#ProteinProteinInteractions
March 4, 2025 at 1:18 PM