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nschnick.bsky.social
I had #Opus5.5 make a demo video (one-shot and also not the real portal/info) to showcase some of the most interesting features! Let me know your thoughts!
#StructuralBiology #UIowaResearch #CoreFacility
September 24, 2026 at 1:55 AM
petrinlab.bsky.social
Excited to share our lab’s new publication in *Human Molecular Genetics*! 🧬By integrating genomic and epigenomic data, we uncovered new insights into the laterality and severity of cleft lip. #Epigenetics #CleftLipAndPalate #TwinsStudies #Uiowa #uiowaresearch
academic.oup.com/hmg/article/...
Genetic and epigenetic contributors to cleft laterality: evidence from monozygotic mirror twins and replication cohorts
Abstract. Nonsyndromic cleft lip (nsCL) exhibits a non-random laterality pattern, with left-sided clefts occurring twice as frequently as right-sided cleft
academic.oup.com
September 11, 2026 at 3:48 PM
petrinlab.bsky.social
I am happy to share that our grant to investigate how genetic and epigenetic factors interact to contribute to orofacial clefts was funded by NIDCR. 🎉 🧬🔬 #CleftLip #OrofacialClefts #Epigenetics #CraniofacialGenetics #uiowaresearch #dnamethylation #meqtl #nidcr
dentistry.uiowa.edu/news/2026/07...
University of Iowa Researcher Receives NIH Grant to Investigate Epigenetic Mechanisms Behind Orofacial Clefts
Aline Petrin, assistant professor at the University of Iowa College of Dentistry, has received a National Institutes of Health award to advance understanding of the biological mechanisms underlying no...
dentistry.uiowa.edu
July 21, 2026 at 3:53 PM
petrinlab.bsky.social
Check out our new paper on meQTLs and orofacial clefts just published in the Molecular Genetics and Genomics journal 🧬 🧪 📖 #CraniofacialResearch #CleftLip #OrofacialClefts #Epigenetics #CraniofacialGenetics #uicod #uiowadentistry #uiowaresearch #dnamethylation #meqtl
rdcu.be/fpTE6
Genetic-epigenetic interactions (meQTLs) in orofacial clefts etiology
rdcu.be
June 28, 2026 at 5:25 PM
petrinlab.bsky.social
The Petrin Lab has been busy. 🧬Two new preprints dropped this week investigating cleft laterality and completeness!🎉
#CleftLip #Laterality #Epigenetics #CraniofacialGenetics #MedRxiv #uicod #uiowadentistry #uiowaresearch #dnamethylation
doi.org/10.1101/2024...
doi.org/10.64898/202...
April 22, 2026 at 8:38 PM
petrinlab.bsky.social
🧬 New preprint alert! Excited to share our twin study on the epigenetics of orofacial clefting — available on #medRxiv. 🔬 🧪
www.medrxiv.org/content/10.6...
#cleftlipandpalate #twinstudies #uiowadentistry #womeninscience #uiowaresearch #nidcr #epigenetics #dnamethylation #EWAS
Epigenetic Signatures in Monozygotic and Dizygotic Twins Discordant for Orofacial Clefts
Introduction: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a common congenital malformation with complex etiology involving both genetic and environmental factors. Epigenetic mechan...
www.medrxiv.org
April 8, 2026 at 3:11 PM
petrinlab.bsky.social
The Petrin Lab is heading to the #IADR2026 General Session next week — and we are buzzing with excitement to share our work! 🦷🧬
#IADR2026 #CraniofacialGenetics #OrofacialClefts #VanDerWoudeSyndrome #Zebrafish #Epigenetics #OAVS #DentalResearch #UIowaDentistry #uicod #womeninscience #uiowaresearch
March 18, 2026 at 5:45 PM
petrinlab.bsky.social
Ready for the 73rd Iowa Section of the AADOCR. Come see our work on Genomics and Epigenomics of Orofacial Clefts and Van der Woude Syndrome. #uiowadentistry #uiowaresearch #cleftlipandpalate #vanderwoude #cleftresearch #epigenetics #dnamethylation #aadocr #womeninscience
February 5, 2026 at 4:59 PM
petrinlab.bsky.social
Our latest research is now available on MedRxiv. We examined laterality and completeness patterns in nonsyndromic cleft lip with or without cleft palate (NSCL/P) across a multiethnic cohort. #uiowaresearch #laterality #cleftresearch #uiowadentistry

www.medrxiv.org/content/10.6...
Laterality and Completeness Patterns of Nonsyndromic Clefts in a Multiethnic Cohort
Objective: Orofacial clefts may involve the complete vertical thickness of the lip (complete) or partial thickness (incomplete). This study evaluates side preference for completeness in nonsyndromic a...
www.medrxiv.org
December 30, 2025 at 2:33 AM
petrinlab.bsky.social
Grateful for the continued support to our research program! 🙏 🧬 🔬 #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #uicod
#womeninscience #vanderwoude
University of Iowa College of Dentistry and Dental Clinics

dentistry.uiowa.edu/news/2025/09...
CRISP grant supports study of genetic variation in Van der Woude syndrome
Aline Petrin, assistant professor of orthodontics, received a CRISP grant to complete genetic screening of patients with Van der Woude syndrome. Her study will help clarify how genetic mutations influ...
dentistry.uiowa.edu
October 3, 2025 at 4:16 PM
petrinlab.bsky.social
Kicking off two days of learning and scientific networking at the University of Minnesota. Come see poster 31 to learn more about our work on Methylation Quantitative Traits and Orofacial Clefts #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #uicod #womeninscience #scgdb2025
September 30, 2025 at 4:06 PM
petrinlab.bsky.social
Another Hatton Award for Iowa! Congratulations, Saba Manafi for winning 2nd place Junior Category! It is so rewarding to see your hard work recognized. #proudmentor 🎉 ❤️ #IADR2025 #uiowadentistry #uiowaresearch #cleftlipandpalate #womeninscience #oavs #PetrinLab
June 25, 2025 at 6:29 PM
petrinlab.bsky.social
Wrapping the #AADOCR2025 meeting in NYC. What an amazing week of learning, networking and reconnecting with friends! #uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #proudmentor #craniofacial #twinstudies #oavs #aadocr2025 🧬 🦷 🔬 🗽
March 15, 2025 at 7:06 PM
petrinlab.bsky.social
Another successful day for the Petrin Lab at #AADOCR2025. Great presentations by these bright young scientists. Thank you for your dedication representing our work!
#uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #proudmentor #twinstudies #aadocr2025 🧬 🦷 🔬
March 13, 2025 at 6:59 PM
petrinlab.bsky.social
#Proudmentor moment! Super congratulations to this amazing young scientist for all her hard work on this project and for winning second place in the #AADOCR2025 Hatton Competition! Next stop - Barcelona 🇪🇸 #IADR2025
#uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #womeninscience #oavs
March 13, 2025 at 12:29 PM
petrinlab.bsky.social
10 days until the #AADOCR2025 in New York City. Come visit our posters and hear from these amazing students about their work on genetic and epigenetics of orofacial clefts. #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #uicod #womeninscience #genetics #twinstudies #nidcr #aadocr2025
March 2, 2025 at 10:45 PM
petrinlab.bsky.social
New preprint from the Petrin Lab: doi.org/10.1101/2025...
We show that non-coding cleft-associated SNPs can affect cleft risk through DNA methylation (meQTLs). #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #womeninscience #twinstudies #nidcr #meqtl
Methylation quantitative loci analysis in nonsyndromic orofacial clefts
Objectives: Nonsyndromic orofacial clefts (OFCs) etiology involves multiple genetic and environmental factors with over 60 identified risk loci; however, they account for a minority of the estimated r...
doi.org
February 12, 2025 at 10:31 PM
petrinlab.bsky.social
Check out our new paper on DNA Methylation Effects on Van der Woude Syndrome Phenotypic Variability. #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #vanderwoudesyndrome #lipits #uicod #womeninscience #proudmentor #nidcr #PetrinLab
doi.org/10.1177/1055...
DNA Methylation Effects on Van der Woude Syndrome Phenotypic Variability - Amanda Seaberg, Waheed Awotoye, Fang Qian, Ligiane A. Machado-Paula, Lindsey Dunlay, Azeez Butali, Jeff Murray, Lina Moreno-...
Objective Van der Woude Syndrome (VWS) presents with combinations of lip pits (LP) and cleft lip and/or cleft palate (CL/P, CPO). VWS phenotypic heterogeneity e...
doi.org
December 10, 2024 at 2:53 AM
aliasgersalem.bsky.social
Tomorrow is One Day for Iowa, and University of Iowa Core Equipment Facilities needs you!
Give to University of Iowa @UIowaResearch Core Equipment Facilities 1dayforiowa.org/VPR25
One Day for Iowa Giving Form
1dayforiowa.org
March 25, 2025 at 11:03 PM