#antisenseoligonucleotides
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sigtrans-sttt.bsky.social
This review highlights the role of #ProteinKinases in #NeurodegenerativeDiseases and explores kinase-targeted strategies—including inhibitors, #AntisenseOligonucleotides, and #GeneTherapy—for early intervention and disease management.

#OpenAccess in #STTT: doi.org/10.1038/s413...
November 8, 2025 at 2:34 PM
jandritu.bsky.social
📅 Deadline: March 15th 📍 Apply here: euraxess.ec.europa.eu/jobs/296420 🌍 About us: effec-dn.eu
Don't miss out—be part of groundbreaking RNA research! 🚀 #PhD #ASO #AntisenseOligonucleotides #ResearchOpportunity #EFFecT
12 PhDs on Antisense oligonucleotide research to foster the full therapeutic potential of antisense technology across tissues
EFFecT (European Training Program to Foster the Full Therapeutic Potential of Antisense Technology across Tissues) is a Marie Skłodowska-Curie Doctoral Network (2025-2028), offering 12 PhD positions.
euraxess.ec.europa.eu
February 17, 2025 at 4:48 PM
ki.se
#AntisenseOligonucleotides (ASOs), used to treat #GeneticDiseases, can affect how cells repair damage to their DNA. New findings published in @natcomms.nature.com may have implications for the development of future genetic medicines 🧪 #pharmaceuticals news.ki.se/synthetic-ge...
Synthetic gene medicines may disrupt DNA repair
Antisense oligonucleotides (ASOs), used to treat genetic diseases, can affect how cells repair damage to their DNA. This is shown in a new study from Karolinska Institutet, published in the journal Na...
news.ki.se
March 3, 2026 at 1:47 PM
sigtrans-sttt.bsky.social
This review summarizes the role of #ProteinKinases in #NeurodegenerativeDiseases, highlighting kinase–kinase networks, signaling pathways, and advances in kinase‑targeted therapies including inhibitors, #AntisenseOligonucleotides, and #GeneTherapy.

#STTT: doi.org/10.1038/s413...
Protein kinases in neurodegenerative diseases: current understandings and implications for drug discovery - Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy - Protein kinases in neurodegenerative diseases: current understandings and implications for drug discovery
doi.org
January 2, 2026 at 2:01 PM
neurodegeneration.bsky.social
[BioRxiv] Neuronal APOE4 reduction with an APOE-I3-targeting ASO protects against neurodegeneration and neuroinflammation in an Alzheimer's disease mouse model

https://doi.org/10.64898/2025.12.10.693468

#neurodegeneration #biorxiv #antisenseoligonucleotides #Alzheimers #ASO #Neurodegeneration
BioRxiv Article
doi.org
December 16, 2025 at 4:25 AM
neurodegeneration.bsky.social
Modulating immune responses in alopecia: therapeutic insights and potential targets of antisense oligonucleotides.

https://pubmed.ncbi.nlm.nih.gov/40181256/

#neurodegeneration #antisenseoligonucleotides
April 4, 2025 at 4:40 PM
sigtrans-sttt.bsky.social
This review discusses small nucleic acid therapeutics, highlighting advances in chemical modifications and delivery platforms, profiles approved drugs like #AntisenseOligonucleotides, #aptamers, and #siRNAs, and addresses clinical challenges.

#STTT: doi.org/10.1038/s413...
November 30, 2025 at 1:30 PM
tonnyjohnson.bsky.social
Patient-Derived Organoids for Gene Therapy Development
www.marinbio.com/patient-deri...

#genetherapy #organoids #precisionmedicine #stemcells #cardiomyoytes #aso #ipsc #antisenseoligonucleotides
Patient-Derived Organoids for Gene Therapy Development
Explore how patient-derived organoids offer a scalable, cost-effective platform for precision medicine, transforming personalized therapeutics and ASO screening.
www.marinbio.com
February 13, 2025 at 4:27 AM