Wow, CD4!
I joined another inspiring convention today in Saint Paul, where folks were fired up to nominate our friend Rep. Betty McCollum.
I joined another inspiring convention today in Saint Paul, where folks were fired up to nominate our friend Rep. Betty McCollum.
May 3, 2026 at 10:09 PM
Wow, CD4!
I joined another inspiring convention today in Saint Paul, where folks were fired up to nominate our friend Rep. Betty McCollum.
I joined another inspiring convention today in Saint Paul, where folks were fired up to nominate our friend Rep. Betty McCollum.
All NJ D Reps have now signed the discharge petition.
NO NJ R Reps have signed.
Rep Smith (CD4) claims he works against human trafficking.
NO NJ R Reps have signed.
Rep Smith (CD4) claims he works against human trafficking.
September 4, 2025 at 2:53 AM
All NJ D Reps have now signed the discharge petition.
NO NJ R Reps have signed.
Rep Smith (CD4) claims he works against human trafficking.
NO NJ R Reps have signed.
Rep Smith (CD4) claims he works against human trafficking.
Los CD4 arriba, el ñerro abajo. Orgullo positivo
October 18, 2025 at 12:32 PM
Los CD4 arriba, el ñerro abajo. Orgullo positivo
What drives immunosenescence—the degradation of function our immune system with aging that increases the risk of age-related diseases?
Today's report: B cells are identified as the bad actors because they induce T cell (CD4) dysfunction and inflammaging
science.org/doi/10.1126/...
Today's report: B cells are identified as the bad actors because they induce T cell (CD4) dysfunction and inflammaging
science.org/doi/10.1126/...
B cells drive CD4 T cell immunosenescence and age-associated health decline
B cells promote CD4 T cell aging and decline in health-span parameters through intercellular communication and nutrient sensing.
science.org
January 30, 2026 at 7:34 PM
What drives immunosenescence—the degradation of function our immune system with aging that increases the risk of age-related diseases?
Today's report: B cells are identified as the bad actors because they induce T cell (CD4) dysfunction and inflammaging
science.org/doi/10.1126/...
Today's report: B cells are identified as the bad actors because they induce T cell (CD4) dysfunction and inflammaging
science.org/doi/10.1126/...
I’ve dedicated my life to service of others. Lauren Boebert only serves herself and her donors. That’s why I’m running for Congress in CD4— because the people of this district deserve better representation than someone who is only out for herself.
#eileenforcolorado #colorado #co04 #laurenboebert
#eileenforcolorado #colorado #co04 #laurenboebert
September 27, 2026 at 6:58 PM
I’ve dedicated my life to service of others. Lauren Boebert only serves herself and her donors. That’s why I’m running for Congress in CD4— because the people of this district deserve better representation than someone who is only out for herself.
#eileenforcolorado #colorado #co04 #laurenboebert
#eileenforcolorado #colorado #co04 #laurenboebert
May 24, 2025 at 3:49 AM
A clear message sent our Rep Dan Newhouse in WA CD4 from Yakima, WA. Thank you former Governor Inslee!
Rep. Dan Newhouse, your constituents—the people you’re *supposed* to be working for—have an important message for you:
April 10, 2025 at 3:50 AM
A clear message sent our Rep Dan Newhouse in WA CD4 from Yakima, WA. Thank you former Governor Inslee!
New Jersey #DontCutOurMedicaid
#CD2 Van Drew 202) 225-6572
#CD4 Smith (202) 225-3765
#CD7 Kean (202) 225-5361
#DemVoice1
bsky.app/profile/did:...
#CD2 Van Drew 202) 225-6572
#CD4 Smith (202) 225-3765
#CD7 Kean (202) 225-5361
#DemVoice1
bsky.app/profile/did:...
February 25, 2025 at 1:21 PM
New Jersey #DontCutOurMedicaid
#CD2 Van Drew 202) 225-6572
#CD4 Smith (202) 225-3765
#CD7 Kean (202) 225-5361
#DemVoice1
bsky.app/profile/did:...
#CD2 Van Drew 202) 225-6572
#CD4 Smith (202) 225-3765
#CD7 Kean (202) 225-5361
#DemVoice1
bsky.app/profile/did:...
This study found that within 7 days of a COVID-19 infection:
•rapid increase in aged and exhausted CD4 and CD8 T cells
•accelerated “immune aging”
•this occurred in all cases regardless of illness severity
•this is specifically a SARS-CoV-2 effect not seen in other infections
•rapid increase in aged and exhausted CD4 and CD8 T cells
•accelerated “immune aging”
•this occurred in all cases regardless of illness severity
•this is specifically a SARS-CoV-2 effect not seen in other infections
Rapid progression of CD8 and CD4 T cells to cellular exhaustion and senescence during SARS-CoV2 infection
Mild to severe COVID-19, but not other respiratory infections, increased cellular senescence and exhaustion in CD4 and CD8 T cells over a 7-d period of inf
academic.oup.com
December 6, 2024 at 1:36 PM
This study found that within 7 days of a COVID-19 infection:
•rapid increase in aged and exhausted CD4 and CD8 T cells
•accelerated “immune aging”
•this occurred in all cases regardless of illness severity
•this is specifically a SARS-CoV-2 effect not seen in other infections
•rapid increase in aged and exhausted CD4 and CD8 T cells
•accelerated “immune aging”
•this occurred in all cases regardless of illness severity
•this is specifically a SARS-CoV-2 effect not seen in other infections
Asthma is a chronic disease characterized by acute, intermittent, recurrent episodes of airway inflammation. A decade of work developing the tools, techniques and collaborations needed to figure out how CD4+ T cells in the lungs propagate disease can be found here:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Tertiary lymphoid structures support the development of allergen-specific progenitor CD4+ T cells
Tissue-resident memory CD4+ T cells (TRM) are key sentinels of the adaptive immune response that provide a rapid, robust inflammatory response upon reactivation in non-lymphoid tissues. While CD4+ TRM...
www.biorxiv.org
October 10, 2025 at 7:22 PM
Asthma is a chronic disease characterized by acute, intermittent, recurrent episodes of airway inflammation. A decade of work developing the tools, techniques and collaborations needed to figure out how CD4+ T cells in the lungs propagate disease can be found here:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Rep Chris Smith, R - NJ4, voted in favor of gutting Medicaid.
There are 177,000 people in CD4 have health insurance through Medicaid. They should all show up at his Toms River office, 33 Washington St tomorrow, Friday 2/28.
He needs to hear from you.
Organizined by @atnj.bsky.social
#DemVoice1
There are 177,000 people in CD4 have health insurance through Medicaid. They should all show up at his Toms River office, 33 Washington St tomorrow, Friday 2/28.
He needs to hear from you.
Organizined by @atnj.bsky.social
#DemVoice1
February 27, 2025 at 5:32 PM
Rep Chris Smith, R - NJ4, voted in favor of gutting Medicaid.
There are 177,000 people in CD4 have health insurance through Medicaid. They should all show up at his Toms River office, 33 Washington St tomorrow, Friday 2/28.
He needs to hear from you.
Organizined by @atnj.bsky.social
#DemVoice1
There are 177,000 people in CD4 have health insurance through Medicaid. They should all show up at his Toms River office, 33 Washington St tomorrow, Friday 2/28.
He needs to hear from you.
Organizined by @atnj.bsky.social
#DemVoice1
Very pleased to share the latest data from the lab, out today in @naturecomms.nature.com ! We show 🧠 infiltrating CD4 Tcells drive inflammatory #microglia proliferation during fungal meningitis, contributing towards early clinical symptoms
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Brain-infiltrating CD4 T cells drive inflammatory microglia proliferation during cryptococcal meningitis in mice
Nature Communications - Cryptococcal meningitis is a common infection in patients with compromised CD4 T cell function. Using a CD4 T cell activation tracking mouse the authors show the...
www.nature.com
October 9, 2025 at 12:16 PM
Very pleased to share the latest data from the lab, out today in @naturecomms.nature.com ! We show 🧠 infiltrating CD4 Tcells drive inflammatory #microglia proliferation during fungal meningitis, contributing towards early clinical symptoms
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Everyone knows that whoever represents CD4 is in charge of citywide policy on unhoused folks. The mayor's hands are tied.
June 9, 2026 at 3:35 PM
Everyone knows that whoever represents CD4 is in charge of citywide policy on unhoused folks. The mayor's hands are tied.
Huh. Well this is neat- endogenous antigen presentation on MHC II is a feature of mRNA vaccines.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Endogenous antigen processing promotes mRNA vaccine CD4+ T cell responses
Lipid nanoparticle (LNP)-encapsulated nucleoside-modified mRNA vaccines elicit robust CD4+ T cell responses, which are essential for antiviral immunity. While peptides presented to CD4+ T cells via ma...
www.biorxiv.org
March 15, 2025 at 2:25 AM
Huh. Well this is neat- endogenous antigen presentation on MHC II is a feature of mRNA vaccines.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Cool paper from the Davis lab using human tonsil organoids to study CD4 and CD8 Tregs. Even though subjects with autoimmunity were excluded, organoids derived from female donors had higher autoreactivity, providing an ex vivo system to study sex differences in response to self antigens. #ImmunoSky 🧪
Differential roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses - Nature Immunology
Here the authors use a tonsil organoid culture model system to investigate the roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses. CD4+ regulatory T cells we...
www.nature.com
February 18, 2025 at 4:33 PM
Cool paper from the Davis lab using human tonsil organoids to study CD4 and CD8 Tregs. Even though subjects with autoimmunity were excluded, organoids derived from female donors had higher autoreactivity, providing an ex vivo system to study sex differences in response to self antigens. #ImmunoSky 🧪
Clear your schedule! The ETA's Kentucky 2026 CD4 Republican Primary report video is premiering TODAY @ 3PM PT / 6PM ET: youtu.be/dOTUAZB50zI
#Kentucky #Data #Analysis #Report #ItCanHappenHere #VerifyTheVote #CountEMAll #CountMEIn #ItsUptoUs #VerifyTHENCertify #Massie #Gallrein
#Kentucky #Data #Analysis #Report #ItCanHappenHere #VerifyTheVote #CountEMAll #CountMEIn #ItsUptoUs #VerifyTHENCertify #Massie #Gallrein
Kentucky 2026 Republican Primary CD4 Shows Statistical Anomalies Warranting Investigation | ETA
Nathan Taylor walks through the ETA's statistical analysis of the 2026 Kentucky CD4 Republican primary, where turnout nearly doubled versus 2024 and a 14-year incumbent lost by 10 points despite…
youtu.be
June 24, 2026 at 8:38 PM
Clear your schedule! The ETA's Kentucky 2026 CD4 Republican Primary report video is premiering TODAY @ 3PM PT / 6PM ET: youtu.be/dOTUAZB50zI
#Kentucky #Data #Analysis #Report #ItCanHappenHere #VerifyTheVote #CountEMAll #CountMEIn #ItsUptoUs #VerifyTHENCertify #Massie #Gallrein
#Kentucky #Data #Analysis #Report #ItCanHappenHere #VerifyTheVote #CountEMAll #CountMEIn #ItsUptoUs #VerifyTHENCertify #Massie #Gallrein
Xin Chen, Mark Davis et al in @natimmunol.bsky.social study on human CD4+ and CD8+ Tregs using a Foxp3 KO approach in human tonsil-derived immune organoids.
#Immunology #Immunosky #organoids
www.nature.com/articles/s41...
#Immunology #Immunosky #organoids
www.nature.com/articles/s41...
Differential roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses - Nature Immunology
Here the authors use a tonsil organoid culture model system to investigate the roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses. CD4+ regulatory T cells we...
www.nature.com
January 14, 2025 at 10:37 PM
Xin Chen, Mark Davis et al in @natimmunol.bsky.social study on human CD4+ and CD8+ Tregs using a Foxp3 KO approach in human tonsil-derived immune organoids.
#Immunology #Immunosky #organoids
www.nature.com/articles/s41...
#Immunology #Immunosky #organoids
www.nature.com/articles/s41...
Are we worried about Mazzei and Bice and Cole and CD4?
September 25, 2026 at 2:09 AM
Are we worried about Mazzei and Bice and Cole and CD4?
Online now, our latest manuscript reporting findings on the metabolic basis of cytokine-driven CD4+ T cell expansion, assessed in vitro and during T cell proliferation following autologous stem cell transplantation.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
IL-7 promotes integrated glucose and amino acid sensing during homeostatic CD4+ T cell proliferation
Interleukin (IL)-7 promotes T cell expansion during lymphopenia. We studied the metabolic basis in CD4+ T cells, observing increased glucose usage for…
www.sciencedirect.com
January 20, 2025 at 1:13 PM
Online now, our latest manuscript reporting findings on the metabolic basis of cytokine-driven CD4+ T cell expansion, assessed in vitro and during T cell proliferation following autologous stem cell transplantation.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
A team in #ScienceTranslationalMedicine untangles the immune mechanisms connecting Epstein-Barr virus to #MultipleSclerosis, showing that CD4+ T cells from patients respond to viral particle components and that this response can be calmed with B cell-depleting therapy. scim.ag/4wL5u4C
CD4+ T cells reactive to Epstein-Barr virus late lytic antigens are enriched in individuals with multiple sclerosis
CD4+ T cells in MS preferentially recognize EBV viral particles rather than latent antigens, and responses are reduced by B cell–targeting therapies.
scim.ag
July 16, 2026 at 5:40 PM
A team in #ScienceTranslationalMedicine untangles the immune mechanisms connecting Epstein-Barr virus to #MultipleSclerosis, showing that CD4+ T cells from patients respond to viral particle components and that this response can be calmed with B cell-depleting therapy. scim.ag/4wL5u4C
Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation - Nature
Dysregulated CD4 T cells that recognize gut commensal antigens are able to infiltrate the central nervous systems and are re-stimulated by host proteins, resulting in neuroinflammation.
www.nature.com
June 18, 2025 at 4:28 PM
Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
We need one of those missing signs for Boebert here in Colorado CD4.
March 8, 2025 at 7:21 PM
We need one of those missing signs for Boebert here in Colorado CD4.
Decent backup CD player cheap from the charity shop.
August 31, 2024 at 2:00 PM
Decent backup CD player cheap from the charity shop.
Tissue-resident memory CD4+ T cells infiltrate the CNS in progressive multiple sclerosis and contribute to chronic autoimmunity in mice | Science Translational Medicine www.science.org/doi/10.1126/... 🧪
Tissue-resident memory CD4+ T cells infiltrate the CNS in progressive multiple sclerosis and contribute to chronic autoimmunity in mice
Tissue-resident memory CD4+ T cells infiltrate the CNS in progressive multiple sclerosis and mouse EAE and contribute to EAE chronicity.
www.science.org
July 23, 2025 at 6:40 PM
Tissue-resident memory CD4+ T cells infiltrate the CNS in progressive multiple sclerosis and contribute to chronic autoimmunity in mice | Science Translational Medicine www.science.org/doi/10.1126/... 🧪