#dendriticcells
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crijournal.bsky.social
Engineered Dendritic Cells Imprint Dual Gut-Homing Specificity on Human Tregs for Pan-Intestinal Immunotolerance

www.dl.begellhouse.com/journals/2ff...

#InflammatoryBowelDisease #RegulatoryTCells #DendriticCells
October 31, 2026 at 7:00 PM
crijournal.bsky.social
Allogeneic Dendritic Cells: Transforming the Impact of Cancer Immunotherapy

www.dl.begellhouse.com/journals/2ff...

#DendriticCells #CancerImmunotherapy #CellTherapy
October 30, 2026 at 7:00 PM
jlbjournal.bsky.social
Emilija Paberalė and colleagues report that monocyte-derived #DendriticCells exhibit a robust and broadly conserved early activation program across immune phenotype-specific #OvarianCancer lysate stimulation conditions
Monocyte-derived dendritic cell activation is broadly conserved across immune phenotype-specific ovarian tumor lysate pools, with donor-associated variation in response magnitude
Monocyte-derived dendritic cell activation was largely conserved across immune phenotype-specific ovarian tumor lysate pools, while response magnitude show
doi.org
November 2, 2026 at 8:17 PM
idoyagalab.bsky.social
What a fantastic start to #DC2026! ☀️

Amazing science, stimulating discussions, and a wonderful international DC community!

And we're just getting started!

In San Diego? It's not too late to join us for a day! 🏖️

www.dc2026sandiego.com

#DendriticCells #Immunology
DC Cells 2026
www.dc2026sandiego.com
October 12, 2026 at 12:51 PM
jlbjournal.bsky.social
Sun-Hwa Kim and colleagues report a metabolite-mediated feedback circuit linking #Neutrophils, commensal #Bacteria, and #DendriticCells in the intestinal mucosa
Metabolite-mediated crosstalk between neutrophils, commensal bacteria, and dendritic cells is associated with intestinal immune responses
Neutrophil-derived lactate attracts commensal Escherichia coli, while commensal-derived short-chain fatty acids restrain neutrophil activation, revealing a
doi.org
October 9, 2026 at 7:17 PM
discovimmunol.bsky.social
🧬 Open‑access study shows spermidine dampens dendritic cell activation via eIF5A hypusination and metabolic adaptation, reducing DC–T cell interactions and shaping immune regulation.

👉 vist.ly/5kesn

#Immunology #DendriticCells #CellMetabolism #OpenAccess
Diagram showing reduced DC and T cell activation with eIF5a and spermidine.
September 30, 2026 at 11:00 AM
alicefrolov.bsky.social
Weakening of the DC–T Cell Immunological Synapse with Age

I am sharing a data visualization from ongoing conceptual work on age-associated remodeling.

#Immunosenescence #DendriticCells #ImmunologicalSynapse #TCellActivation #Costimulation #LigandReceptorInteractions
Weakening of the DC–T Cell Immunological Synapse with Age I am sharing a data visualization from ongoing conceptual work on age-associated remodeling of dendritic cell–T cell communication at the immunological synapse. The figure, "Weakening of the DC–T Cell Immunological Synapse with Age," is rendered as a curved bipartite flow map (ligand-receptor arc diagram), with dendritic cell ligands on the left axis and cognate T cell receptors on the right. Arc width and opacity encode simulated signaling strength, contrasted between young and aged tissue states. I want to be explicit that the underlying values are simulated. They are not drawn from a single empirical dataset but are parameterized to reproduce trends consistently reported in the immunosenescence literature. The visualization is intended as a mechanistic scaffold for discussion rather than as primary evidence. The mapped interactions include the peptide-MHC Class II to TCR-CD3 axis, the costimulatory CD80/CD86 to CD28 pair, CD40 to CD40L feedback, ICAM-1 to LFA-1 adhesion, and inhibitory PD-L1 to PD-1 signaling. In the aged condition, the diagram depicts attenuated pMHCII–TCR and CD80/86–CD28 arc weights, consistent with reduced antigen presentation efficiency and diminished costimulatory competence in aged DCs. Concurrently, the PD-L1–PD-1 arc is broadened, reflecting the shift toward inhibitory tone described in exhausted and senescent T cell compartments. ICAM-1–LFA-1 attenuation is included to represent reported deficits in synapse stability and conjugate formation. The composite effect illustrated here is a quantitative and qualitative degradation of productive synaptic signaling, favoring incomplete T cell priming and skewed activation thresholds. I would welcome critique on the ligand-receptor pair selection and on plausible weighting priors that could later be constrained with single-cell interactome or spatial proteomic data.
September 28, 2026 at 5:31 PM
gmj-georgia.bsky.social
New laboratory research reveals creatine may strengthen cancer-fighting immune pathways by energizing dendritic cells that activate killer T c…

#Cancerimmunotherapy #Creatine #Dendriticcells #Immunemetabolism #Translationalresearch

#Cancerimmunotherapy #Creatine #Dendriticcells #Immunemetabolis…
Can Creatine Enhance Cancer Immunity?
New laboratory research reveals creatine may strengthen cancer-fighting immune pathways by energizing dendritic cells that activate killer T c… #Cancerimmunotherapy #Creatine #Dendriticcells #Immunemetabolism #Translationalresearch
news.gmj.ge
September 24, 2026 at 9:26 PM
eurjimmunol.bsky.social
📢 Volume 2 of EJI's Special Collection on DC Biology is now open for submissions!
Following the success of EJI's Special Collection on Guidelines and Advances in Basic and Applied Dendritic Cell Biology bit.ly/4xq7X4E, we are delighted to launch Volume 2 in collaboration with the AKDC of the DGfI.
A sincere thank you to the AKDC and the Deutsche Gesellschaft für Immunologie e.V. (DGfI) for their continued trust, support, and partnership in this initiative. Special thanks to our enthusiastic guest editors Björn Clausen Diana Dudziak Stella Autenrieth Anne Krug Questions or interested in contributing? Please contact ejied@wiley.com or reach out to the AKDC speakers and guest editors. #Immunology #DendriticCells European Federation of Immunological Societies yEFIS Deutsche Gesellschaft für Immunologie e.V. (DGfI)DGFI Young Immunologists Questions or interested in contributing? Please contact ejied@wiley.com or reach out to the AKDC speakers and guest editors. #Immunology #DendriticCells European Federation of Immunological Societies yEFIS Deutsche Gesellschaft für Immunologie e.V. (DGfI)DGFI Young Immunologists
September 23, 2026 at 3:16 PM
sigtrans-sttt.bsky.social
A vaccine carrier can do more than deliver antigens!

HlaH35A activates ADAM10–Notch2 signaling in #dendriticcells, promoting cDC2 differentiation and Th17/Tfh immunity to protect against acute Pseudomonas aeruginosa #LungInfection.

#STTT #OpenAccess: doi.org/10.1038/s413...
#Immunology
Alpha hemolysin enhances the immune response by modulating dendritic cell differentiation via ADAM10-Notch signaling
September 5, 2026 at 2:00 AM
idoyagalab.bsky.social
Harnessing #DendriticCells for therapeutics: cancer & beyond! 🚀

Shalin Naik, Filipe Pereira, Ira Mellman, Virginia Pascual & many more take #DC2026 from discovery to translation!

⏰ FINAL DAY! Late-Breaking Abstracts close TONIGHT!

Don’t miss your chance to join us 🌴!

🙏🔁
August 28, 2026 at 4:15 PM
idoyagalab.bsky.social
Inside the tumor: how do #DendriticCells shape cancer immunity?

Meet our #DC2026 Plenary 6 speakers Miriam Merad, Santiago Zelenay & Max Krummel!

⏰ Last chance! Late-Breaking Abstracts close TOMORROW, August 28!

🙏🔁
August 27, 2026 at 9:13 PM
discovimmunol.bsky.social
🧬 Open‑access study shows spermidine dampens dendritic cell activation via eIF5A hypusination and metabolic adaptation, reducing DC–T cell interactions and shaping immune regulation.

👉 vist.ly/5g6y5

#Immunology #DendriticCells #CellMetabolism #OpenAccess
Diagram showing reduced DC and T cell activation with eIF5a and spermidine.
August 26, 2026 at 10:25 AM
researcherplus.bsky.social
Paper of the Day ! 📄

One kind of immune messenger cell builds then keeps tumor immune hubs alive. Would you want treatments that boost these cells in tumors?

Paper: doi.org/10.1158/2159-8290.cd-rw2026-075

#dendriticcells #tertiarylymphoidstructures #cancerimmunotherapy #paperoftheday
Dendritic Cells Establish and Maintain Tertiary Lymphoid Structure and Function
Tertiary lymphoid structures (TLS), which are organized aggregates of T cells, B cells, and stromal elements that arise within tumors, are associated with improved outcomes and stronger responses to i...
doi.org
August 25, 2026 at 5:37 PM
idoyagalab.bsky.social
Keep calm or fight back? How do #DendriticCells make the call at mucosal barriers?

Meet our #DC2026 Plenary 5 speakers: William Agace, Daniel Mucida & Marco Colonna!

⏰ Late-Breaking Abstracts are OPEN through August 28. Bring your latest science and join the global DC community!

🙏🔁
August 25, 2026 at 3:09 PM
idoyagalab.bsky.social
Skin deep! How do #DendriticCells instruct #Tcells to protect the skin?

Meet our #DC2026 Plenary 4 speakers: Clare Bennett, Tiffany Scharschmidt & Laura Mackay!

⏰ Late-Breaking Abstracts are OPEN through August 28. Bring your latest science and join the global DC community!

🙏🔁
August 25, 2026 at 12:23 AM
idoyagalab.bsky.social
DCs on the move! How do #DendriticCells patrol tissues and coordinate immunity?

Meet our #DC2026 Plenary 3 speakers: Sophie Janssens, Shannon Turley & Ana-Maria Lennon-Duménil!

⏰ Late-Breaking Abstracts are OPEN through August 28. Join the global DC community!

🙏🔁
August 21, 2026 at 2:06 PM
idoyagalab.bsky.social
One family, many functions: from identity to function in #DendriticCells!

Meet our #DC2026 Plenary 2 speakers: Dan Littman, Chrys Brown & Barbara Schraml!

⏰ Late-Breaking Abstracts are OPEN through August 28. Bring your latest science and join the global DC community!

🙏🔁
August 20, 2026 at 2:40 PM
idoyagalab.bsky.social
Where do #DendriticCells come from, and what makes them who they are?

Meet our #DC2026 Plenary 1 speakers: Kenneth Murphy, Tomohiko Tamura & Florent Ginhoux!

⏰ Late-Breaking Abstracts are OPEN through August 28. Bring your latest science and join the global DC community!

🙏🔁
August 19, 2026 at 1:33 PM
isabel-stoetzel.bsky.social
Finally, my PhD project is published! 🎉

I am thankful to all the collaborators who made this possible!

www.nature.com/articles/s41...

@natcomms.nature.com
#dendriticcells #immunesynapse #centrosome
January 15, 2026 at 7:39 AM
castltrastondrs.medsky.network
#Tcells, #Bcells, #macrophages, #neutrophils, #dendriticcells, & NK cells.
They are involved in their differentiation, activation & immune responses.
- Autoimmune Disease Pathogenesis: Emerging evidence suggests that
August 15, 2025 at 11:09 AM
castltrastondrs.medsky.network
The adaptive immunity response, incl neutralizing viral-specific #antibodies produced by #Bcells & memory (m)T cells, are orchestrated by professional antigen-presenting cells, #dendriticcells & T helper cells.
April 4, 2025 at 12:36 PM
castltrastondrs.medsky.network
#MedSky🧪 #IDSky Fungal Messenger Impairs Immune Cell Function . #Farnesol (produced by C. albicans) that signaling molecule, alters lipid synthesis in #dendriticcells, causing mitochondrial dysfunction decreased inflammatory responding. Overgrowth of C. albicans has been a factor in worse #COVID .
November 8, 2024 at 6:45 PM
castltrastondrs.medsky.network
#Adaptiveimmunity is generated in #lymphatic organs, which are usually remote from the primary site of infection, requiring long-range cellular trafficking. #dendriticcells can “self-shape” the chemotactic gradients that help them transport antigens to lymph nodes

www.science.org/doi/10.1126/...
September 7, 2023 at 4:57 AM
yefis-immunology.bsky.social
If they were competing in Olympics, their category would be a relay race. 🏁🏃‍♀️💨

#yefis #immunecells #immunity #immunesystem #immunology #dendriticcells
March 19, 2025 at 10:07 AM