🚨 New study in @pnas.org ! 🚨
We identified MITD1, a brain-specific interferon-inducible factor that 𝗶𝗻𝗵𝗶𝗯𝗶𝘁𝘀 𝗳𝗹𝗮𝘃𝗶𝘃𝗶𝗿𝘂𝘀 𝗿𝗲𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻, including WNV, USUV, ZIKV & DENV.
🔗 Read the paper: www.pnas.org/doi/10.1073/...
👇 Thread with take-home messages below!
#Virology #Flavivirus #Interferon
We identified MITD1, a brain-specific interferon-inducible factor that 𝗶𝗻𝗵𝗶𝗯𝗶𝘁𝘀 𝗳𝗹𝗮𝘃𝗶𝘃𝗶𝗿𝘂𝘀 𝗿𝗲𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻, including WNV, USUV, ZIKV & DENV.
🔗 Read the paper: www.pnas.org/doi/10.1073/...
👇 Thread with take-home messages below!
#Virology #Flavivirus #Interferon
MITD1 is a brain-specific interferon-inducible factor that inhibits flavivirus replication | PNAS
West Nile virus (WNV) and Usutu virus (USUV) are closely related mosquito-borne neurotropic
flaviviruses that share common transmission cycle and c...
www.pnas.org
March 20, 2025 at 8:40 PM
🚨 New study in @pnas.org ! 🚨
We identified MITD1, a brain-specific interferon-inducible factor that 𝗶𝗻𝗵𝗶𝗯𝗶𝘁𝘀 𝗳𝗹𝗮𝘃𝗶𝘃𝗶𝗿𝘂𝘀 𝗿𝗲𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻, including WNV, USUV, ZIKV & DENV.
🔗 Read the paper: www.pnas.org/doi/10.1073/...
👇 Thread with take-home messages below!
#Virology #Flavivirus #Interferon
We identified MITD1, a brain-specific interferon-inducible factor that 𝗶𝗻𝗵𝗶𝗯𝗶𝘁𝘀 𝗳𝗹𝗮𝘃𝗶𝘃𝗶𝗿𝘂𝘀 𝗿𝗲𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻, including WNV, USUV, ZIKV & DENV.
🔗 Read the paper: www.pnas.org/doi/10.1073/...
👇 Thread with take-home messages below!
#Virology #Flavivirus #Interferon
New in @science.org
We built a safe, atomic-resolution version of the Powassan virus—a deadly tick-borne #flavivirus with no vaccine.
✅ First structure ever
✅ Safe to handle (BSL-2)
✅ Platform for vaccines & antivirals
Let me show you 🧵 (1/5)
Link: www.science.org/doi/10.1126/...
We built a safe, atomic-resolution version of the Powassan virus—a deadly tick-borne #flavivirus with no vaccine.
✅ First structure ever
✅ Safe to handle (BSL-2)
✅ Platform for vaccines & antivirals
Let me show you 🧵 (1/5)
Link: www.science.org/doi/10.1126/...
Atomic-resolution structure of a chimeric Powassan tick-borne flavivirus
The 2.8-Å resolution structure is presented for a chimeric construct of an emerging tick-borne flavivirus, Powassan virus.
www.science.org
July 9, 2025 at 8:11 PM
New in @science.org
We built a safe, atomic-resolution version of the Powassan virus—a deadly tick-borne #flavivirus with no vaccine.
✅ First structure ever
✅ Safe to handle (BSL-2)
✅ Platform for vaccines & antivirals
Let me show you 🧵 (1/5)
Link: www.science.org/doi/10.1126/...
We built a safe, atomic-resolution version of the Powassan virus—a deadly tick-borne #flavivirus with no vaccine.
✅ First structure ever
✅ Safe to handle (BSL-2)
✅ Platform for vaccines & antivirals
Let me show you 🧵 (1/5)
Link: www.science.org/doi/10.1126/...
Structures of asymmetric particles of tick-borne encephalitis virus provide insight into flavivirus assembly and maturation www.science.org/doi/10.1126/...
Structures of asymmetric particles of tick-borne encephalitis virus provide insight into flavivirus assembly and maturation
Flavivirus maturation is enabled by asymmetric rearrangement of the virus envelope proteins.
www.science.org
July 6, 2026 at 9:18 PM
Structures of asymmetric particles of tick-borne encephalitis virus provide insight into flavivirus assembly and maturation www.science.org/doi/10.1126/...
Our paper is finally out!
I’m proud to share this collaborative work using FIB milling and cryo-electron tomography to study tick-borne flavivirus replication. Thanks to all co-authors and collaborators — great teamwork #CryoET #ElectronTomography #Virology #Flavivirus #Microscopy #StructuralBiology
I’m proud to share this collaborative work using FIB milling and cryo-electron tomography to study tick-borne flavivirus replication. Thanks to all co-authors and collaborators — great teamwork #CryoET #ElectronTomography #Virology #Flavivirus #Microscopy #StructuralBiology
I am super happy to share this paper in its final form. We used FIB milling to "dig in to" cell lines and mouse brains infected with tick-borne flaviviruses, followed by cryo-ET to study the virus replication. It's open access, so have a look!
#virology #teamtomo
www.nature.com/articles/s41...
#virology #teamtomo
www.nature.com/articles/s41...
Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation - Nature Communications
In this study, Dahmane et al use a method called cryo-electron tomography to uncover new details of how tick-borne flaviviruses transform cells into virus factories.
www.nature.com
January 23, 2026 at 9:28 PM
Our paper is finally out!
I’m proud to share this collaborative work using FIB milling and cryo-electron tomography to study tick-borne flavivirus replication. Thanks to all co-authors and collaborators — great teamwork #CryoET #ElectronTomography #Virology #Flavivirus #Microscopy #StructuralBiology
I’m proud to share this collaborative work using FIB milling and cryo-electron tomography to study tick-borne flavivirus replication. Thanks to all co-authors and collaborators — great teamwork #CryoET #ElectronTomography #Virology #Flavivirus #Microscopy #StructuralBiology
New research article in The Lancet Microbe
#YellowFever breakthrough infections after yellow fever vaccination: a systematic review and meta-analysis
www.thelancet.com/journals/lan...
#IDSky #ViroSky #MicroSky #flavivirus #OpenAccess #OA
#YellowFever breakthrough infections after yellow fever vaccination: a systematic review and meta-analysis
www.thelancet.com/journals/lan...
#IDSky #ViroSky #MicroSky #flavivirus #OpenAccess #OA
November 7, 2024 at 12:25 PM
New research article in The Lancet Microbe
#YellowFever breakthrough infections after yellow fever vaccination: a systematic review and meta-analysis
www.thelancet.com/journals/lan...
#IDSky #ViroSky #MicroSky #flavivirus #OpenAccess #OA
#YellowFever breakthrough infections after yellow fever vaccination: a systematic review and meta-analysis
www.thelancet.com/journals/lan...
#IDSky #ViroSky #MicroSky #flavivirus #OpenAccess #OA
At the Dutch Vaccine Symposium 😁 with Frerik presenting our work on flavivirus antigen design.
September 17, 2026 at 7:57 AM
At the Dutch Vaccine Symposium 😁 with Frerik presenting our work on flavivirus antigen design.
Really cool work from @thehornerlab.bsky.social and colleagues highlighting a role for the UFMylation post-translational modification system in flavivirus viral particle production!
UFMylation promotes orthoflavivirus infectious particle production https://www.biorxiv.org/content/10.1101/2025.01.09.632082v1
January 11, 2025 at 5:35 AM
Really cool work from @thehornerlab.bsky.social and colleagues highlighting a role for the UFMylation post-translational modification system in flavivirus viral particle production!
Looking very much forward to visiting Gisa @geroldlab.bsky.social at Medical University Innsbruck tomorrow - discussing our recent studies on tick-borne encephalitis and future flavivirus projects 🌸
October 22, 2025 at 2:45 PM
Looking very much forward to visiting Gisa @geroldlab.bsky.social at Medical University Innsbruck tomorrow - discussing our recent studies on tick-borne encephalitis and future flavivirus projects 🌸
Mosquito–capsid interactions contribute to flavivirus vector specificity
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Mosquito–capsid interactions contribute to flavivirus vector specificity - Nature
Systemic flavivirus dissemination in mosquitoes following initial infection requires protein–protein interactions within extracellular vesicles, which enable infectious particles to be transported thr...
www.nature.com
February 5, 2026 at 2:33 PM
Mosquito–capsid interactions contribute to flavivirus vector specificity
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Yellow4FLAVI's Bluesky account is now live!! #EUproject funded by @EU_HaDEA
#HorizonEurope #Health Visit our website yellow4flavi.eu #flavivirus #yellowfever #vaccine #pandemic #zika #dengue #lifesciences #EUcooperation
#HorizonEurope #Health Visit our website yellow4flavi.eu #flavivirus #yellowfever #vaccine #pandemic #zika #dengue #lifesciences #EUcooperation
Yellow4FLAVI | Inform flavivirus vaccine design
Yellow4FLAVI Project. Deconstructing the protective immunity of yellow fever virus 17D to inform flavivirus vaccine design.
yellow4flavi.eu
December 27, 2024 at 2:01 PM
Yellow4FLAVI's Bluesky account is now live!! #EUproject funded by @EU_HaDEA
#HorizonEurope #Health Visit our website yellow4flavi.eu #flavivirus #yellowfever #vaccine #pandemic #zika #dengue #lifesciences #EUcooperation
#HorizonEurope #Health Visit our website yellow4flavi.eu #flavivirus #yellowfever #vaccine #pandemic #zika #dengue #lifesciences #EUcooperation
Exciting work by Dr Andrii Slonchak on using virus-inclusive scRNA-Seq to reveal the mechanism of flavivirus neuropathogenesis #lorneiandi
February 20, 2025 at 1:06 AM
Exciting work by Dr Andrii Slonchak on using virus-inclusive scRNA-Seq to reveal the mechanism of flavivirus neuropathogenesis #lorneiandi
Infection with Japanese encephalitis virus, a mosquito-borne flavivirus, was identified in a patient who received a liver transplant from a donor who resided in California. Read the full report: nej.md/4uPTWNf
#MedSky #IDSky
#MedSky #IDSky
March 29, 2026 at 7:02 PM
Infection with Japanese encephalitis virus, a mosquito-borne flavivirus, was identified in a patient who received a liver transplant from a donor who resided in California. Read the full report: nej.md/4uPTWNf
#MedSky #IDSky
#MedSky #IDSky
Our article discovering excreta-mediated transmission of #flavivirus in #mosquito population is featured in iScience.
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
West Nile virus can be transmitted within mosquito populations through infectious mosquito excreta
Tropical medicine; Disease; Pathogenic organism
www.cell.com
December 3, 2024 at 6:20 AM
Our article discovering excreta-mediated transmission of #flavivirus in #mosquito population is featured in iScience.
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
We are looking forward welcoming you on May 12th for Prof. Ebel's @ebellaboratory.bsky.social webinar "Flavivirus vector interactions: Probing flavivirus population biology at the virus-host interface." Register:
www.zoomgov.com/webinar/regi...
@utmbhealth.bsky.social @astmh.bsky.social
www.zoomgov.com/webinar/regi...
@utmbhealth.bsky.social @astmh.bsky.social
April 30, 2026 at 2:50 PM
We are looking forward welcoming you on May 12th for Prof. Ebel's @ebellaboratory.bsky.social webinar "Flavivirus vector interactions: Probing flavivirus population biology at the virus-host interface." Register:
www.zoomgov.com/webinar/regi...
@utmbhealth.bsky.social @astmh.bsky.social
www.zoomgov.com/webinar/regi...
@utmbhealth.bsky.social @astmh.bsky.social
*flertando*
O HCV pertence a família dos flavivirus (Flaviviridae), junto com a dengue e a febre amarela. Recentemente, os vírus que pertencem ao gênero "Flavivirus" e que estavam na família Flaviviridae foram renomeados para orthoflavivirus, para evitar confusão taxonômica entre gênero e família.
O HCV pertence a família dos flavivirus (Flaviviridae), junto com a dengue e a febre amarela. Recentemente, os vírus que pertencem ao gênero "Flavivirus" e que estavam na família Flaviviridae foram renomeados para orthoflavivirus, para evitar confusão taxonômica entre gênero e família.
*flertando*
a transformada de Fourier serve pra decompor uma onda em componentes de frequência, basta convolver a resposta ao impulso com a função alvo, com base na assinatura de frequência você pode comprimir a onda original fazendo uma quantização, ou computar uma assinatura sonora pra reconhecim
a transformada de Fourier serve pra decompor uma onda em componentes de frequência, basta convolver a resposta ao impulso com a função alvo, com base na assinatura de frequência você pode comprimir a onda original fazendo uma quantização, ou computar uma assinatura sonora pra reconhecim
May 25, 2026 at 8:37 PM
*flertando*
O HCV pertence a família dos flavivirus (Flaviviridae), junto com a dengue e a febre amarela. Recentemente, os vírus que pertencem ao gênero "Flavivirus" e que estavam na família Flaviviridae foram renomeados para orthoflavivirus, para evitar confusão taxonômica entre gênero e família.
O HCV pertence a família dos flavivirus (Flaviviridae), junto com a dengue e a febre amarela. Recentemente, os vírus que pertencem ao gênero "Flavivirus" e que estavam na família Flaviviridae foram renomeados para orthoflavivirus, para evitar confusão taxonômica entre gênero e família.
Mosquito salivary gland extracts enhance flavivirus pathogenicity through TLR2-mediated recruitment of immune cells @cp-cellreports.bsky.social
www.cell.com/cell-reports...
www.cell.com/cell-reports...
September 1, 2025 at 5:40 PM
Mosquito salivary gland extracts enhance flavivirus pathogenicity through TLR2-mediated recruitment of immune cells @cp-cellreports.bsky.social
www.cell.com/cell-reports...
www.cell.com/cell-reports...
A sphingomyelin shield for flaviviruses | Science Signaling www.science.org/doi/10.1126/... 🧪
A sphingomyelin shield for flaviviruses
Sphingomyelins in mosquito saliva enhance flavivirus infection by preventing viral protein degradation.
www.science.org
July 22, 2025 at 9:14 PM
A sphingomyelin shield for flaviviruses | Science Signaling www.science.org/doi/10.1126/... 🧪
The kinase RIPK3 suppresses pathologic neuroinflammation in mouse models of flavivirus infection @
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
July 15, 2025 at 8:29 PM
The kinase RIPK3 suppresses pathologic neuroinflammation in mouse models of flavivirus infection @
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
preprint advancing #flavivirus transmission understanding: 1. Flavivirus-infected #mosquito saliva always contain sfRNA inside lipide #vesicles. 2. Salivary sfRNA increases transmission by inhibiting MDA5-mediated interferon signalling.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Multiple orthoflaviviruses secrete sfRNA in mosquito saliva to promote transmission by inhibiting MDA5-mediated early interferon response
Numerous orthoflaviviruses transmitted through the bites of different mosquito species infect more than 500 million people annually. Bite-initiated skin infection represents a critical and conserved s...
www.biorxiv.org
January 24, 2025 at 8:45 PM
preprint advancing #flavivirus transmission understanding: 1. Flavivirus-infected #mosquito saliva always contain sfRNA inside lipide #vesicles. 2. Salivary sfRNA increases transmission by inhibiting MDA5-mediated interferon signalling.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Meet SHIELD ! ✋
Today: The FlavImmunity group at Institut Pasteur uses the yellow fever 17D vaccine as a model to study flavivirus entry, maturation, and antigenicity.
research.pasteur.fr/en/team/flav...
#Flavivirus #VaccineResearch #StructuralBiology #YellowFever #InstitutPasteur #SHIELDproject
Today: The FlavImmunity group at Institut Pasteur uses the yellow fever 17D vaccine as a model to study flavivirus entry, maturation, and antigenicity.
research.pasteur.fr/en/team/flav...
#Flavivirus #VaccineResearch #StructuralBiology #YellowFever #InstitutPasteur #SHIELDproject
June 25, 2025 at 2:58 PM
Meet SHIELD ! ✋
Today: The FlavImmunity group at Institut Pasteur uses the yellow fever 17D vaccine as a model to study flavivirus entry, maturation, and antigenicity.
research.pasteur.fr/en/team/flav...
#Flavivirus #VaccineResearch #StructuralBiology #YellowFever #InstitutPasteur #SHIELDproject
Today: The FlavImmunity group at Institut Pasteur uses the yellow fever 17D vaccine as a model to study flavivirus entry, maturation, and antigenicity.
research.pasteur.fr/en/team/flav...
#Flavivirus #VaccineResearch #StructuralBiology #YellowFever #InstitutPasteur #SHIELDproject
I am super happy to share this paper in its final form. We used FIB milling to "dig in to" cell lines and mouse brains infected with tick-borne flaviviruses, followed by cryo-ET to study the virus replication. It's open access, so have a look!
#virology #teamtomo
www.nature.com/articles/s41...
#virology #teamtomo
www.nature.com/articles/s41...
Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation - Nature Communications
In this study, Dahmane et al use a method called cryo-electron tomography to uncover new details of how tick-borne flaviviruses transform cells into virus factories.
www.nature.com
January 23, 2026 at 4:47 PM
I am super happy to share this paper in its final form. We used FIB milling to "dig in to" cell lines and mouse brains infected with tick-borne flaviviruses, followed by cryo-ET to study the virus replication. It's open access, so have a look!
#virology #teamtomo
www.nature.com/articles/s41...
#virology #teamtomo
www.nature.com/articles/s41...
Join Prof Gong Cheng (Tsinghua University) for our International Arbovirus Biology Seminar, exploring the molecular basis of flavivirus infection in mosquitoes and determinants of vector competence.
All welcome! Please help with a repost.
#Arbovirus #Flavivirus #VectorBiology
All welcome! Please help with a repost.
#Arbovirus #Flavivirus #VectorBiology
March 11, 2026 at 2:41 PM
Join Prof Gong Cheng (Tsinghua University) for our International Arbovirus Biology Seminar, exploring the molecular basis of flavivirus infection in mosquitoes and determinants of vector competence.
All welcome! Please help with a repost.
#Arbovirus #Flavivirus #VectorBiology
All welcome! Please help with a repost.
#Arbovirus #Flavivirus #VectorBiology
New preprint on flavivirus-host interactions with friend and collaborator Armando who spent a couple of months visiting the lab to do the interactomics with us.
Another new preprint! This time looking at flavivirus NS5 interactions with our collaborator Armando Arias - www.biorxiv.org/content/10.6...
Mitophagy-related prohibitin 2 is an orthoflavivirus restriction factor targeted for degradation during infection
Mitophagy selectively removes depolarised and damaged mitochondria, promoting cell viability. Some members of the Orthoflavivirus genus activate mitophagy to allow extended replication times in a surv...
www.biorxiv.org
December 6, 2025 at 11:41 AM
New preprint on flavivirus-host interactions with friend and collaborator Armando who spent a couple of months visiting the lab to do the interactomics with us.
Excited to announce that our collaboration with @briandaniels.bsky.social has been published today! So happy for everyone involved, but especially me and Marissa 😆. Check it out if you're interested in #neuroinflammation and the #BBB www.science.org/doi/10.1126/...
Astrocytic RIPK3 exerts protective anti-inflammatory activity in mice with viral encephalitis by transcriptional induction of serpins
The kinase RIPK3 suppresses pathologic neuroinflammation in mouse models of flavivirus infection.
www.science.org
July 15, 2025 at 10:01 PM
Excited to announce that our collaboration with @briandaniels.bsky.social has been published today! So happy for everyone involved, but especially me and Marissa 😆. Check it out if you're interested in #neuroinflammation and the #BBB www.science.org/doi/10.1126/...