The Seminal Vesicles bit from Letterkenny remains one of the funniest things I’ve ever seen
Letterkenny | Season 1 | Florida State Seminal Vesicles
YouTube video by Letterkenny Problems
youtu.be
September 11, 2026 at 12:24 AM
The Seminal Vesicles bit from Letterkenny remains one of the funniest things I’ve ever seen
Our first deposition of synaptic vesicles segmentations is now in the Cryo ET Portal! We segmented vesicles in over 50 tomograms to enable analysis of membrane proteins and more.
cryoetdataportal.czscience.com/depositions/...
cryoetdataportal.czscience.com/depositions/...
February 21, 2025 at 6:57 AM
Our first deposition of synaptic vesicles segmentations is now in the Cryo ET Portal! We segmented vesicles in over 50 tomograms to enable analysis of membrane proteins and more.
cryoetdataportal.czscience.com/depositions/...
cryoetdataportal.czscience.com/depositions/...
Extracellular vesicles inside cells wait a minute
April 24, 2025 at 7:47 AM
Extracellular vesicles inside cells wait a minute
Fun study from Misha Kudryashev @mdc-berlin.bsky.social in @pnas.org .
CryoEM, Alpha fold & proteomics show V-ATPase is in a complex with Synaptophysin. Synaptic vesicles can be partially coated by clathrin. Also see assembled clathrin baskets without vesicles.
www.pnas.org/doi/10.1073/...
CryoEM, Alpha fold & proteomics show V-ATPase is in a complex with Synaptophysin. Synaptic vesicles can be partially coated by clathrin. Also see assembled clathrin baskets without vesicles.
www.pnas.org/doi/10.1073/...
Molecular architecture of synaptic vesicles | PNAS
Synaptic vesicles (SVs) store and transport neurotransmitters to the presynaptic active
zone for release by exocytosis. After release, SV proteins ...
www.pnas.org
December 1, 2024 at 2:43 PM
Fun study from Misha Kudryashev @mdc-berlin.bsky.social in @pnas.org .
CryoEM, Alpha fold & proteomics show V-ATPase is in a complex with Synaptophysin. Synaptic vesicles can be partially coated by clathrin. Also see assembled clathrin baskets without vesicles.
www.pnas.org/doi/10.1073/...
CryoEM, Alpha fold & proteomics show V-ATPase is in a complex with Synaptophysin. Synaptic vesicles can be partially coated by clathrin. Also see assembled clathrin baskets without vesicles.
www.pnas.org/doi/10.1073/...
Our new paper is out! "Extracellular vesicles, including large translating vesicles called midbody remnants, are released during the cell cycle"
We show that all sizes of EVs are released during the cell cycle particularly translating RNA-enriched MBRs.
www.molbiolcell.org/doi/abs/10.1...
We show that all sizes of EVs are released during the cell cycle particularly translating RNA-enriched MBRs.
www.molbiolcell.org/doi/abs/10.1...
Extracellular vesicles, including large translating vesicles called midbody remnants, are released during the cell cycle | Molecular Biology of the Cell
Extracellular vesicles (EVs) play crucial roles in cell-cell communication, but the biogenesis of large EVs has remained elusive. Here, we show that the biogenesis of large EVs (>800nm-2um) occurs pre...
www.molbiolcell.org
November 14, 2024 at 4:53 PM
Our new paper is out! "Extracellular vesicles, including large translating vesicles called midbody remnants, are released during the cell cycle"
We show that all sizes of EVs are released during the cell cycle particularly translating RNA-enriched MBRs.
www.molbiolcell.org/doi/abs/10.1...
We show that all sizes of EVs are released during the cell cycle particularly translating RNA-enriched MBRs.
www.molbiolcell.org/doi/abs/10.1...
A lime is a citrus fruit, which is typically round, lime green in colour, in diameter, and contains acidic juice vesicles.
January 8, 2025 at 3:37 PM
A lime is a citrus fruit, which is typically round, lime green in colour, in diameter, and contains acidic juice vesicles.
Hardly anyone has complimented my seminal vesicles today
December 7, 2024 at 3:24 PM
Hardly anyone has complimented my seminal vesicles today
We've all heard of EVs for drug delivery, but what about intracellular vesicles?
Small intracellular vesicles outperform small extracellular vesicles in uptake, drug delivery and retinal neuroprotection | Nature Biomedical Engineering share.google/xWrOtYU4ElbJ...
Small intracellular vesicles outperform small extracellular vesicles in uptake, drug delivery and retinal neuroprotection | Nature Biomedical Engineering share.google/xWrOtYU4ElbJ...
Small intracellular vesicles outperform small extracellular vesicles in uptake, drug delivery and retinal neuroprotection - Nature Biomedical Engineering
A protocol to isolate small intracellular vesicles from human cells is reported; these are molecularly distinct from small extracellular vesicles and show superior therapeutic potential in retinal deg...
share.google
January 19, 2026 at 12:34 PM
We've all heard of EVs for drug delivery, but what about intracellular vesicles?
Small intracellular vesicles outperform small extracellular vesicles in uptake, drug delivery and retinal neuroprotection | Nature Biomedical Engineering share.google/xWrOtYU4ElbJ...
Small intracellular vesicles outperform small extracellular vesicles in uptake, drug delivery and retinal neuroprotection | Nature Biomedical Engineering share.google/xWrOtYU4ElbJ...
Study: Possible long COVID biomarker: identification of SARC-CoV-2 related protein(s) in Serum Extracellular Vesicles
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Possible long COVID biomarker: identification of SARC-CoV-2 related protein(s) in Serum Extracellular Vesicles - Infection
Infection -
link.springer.com
August 13, 2025 at 4:49 AM
Study: Possible long COVID biomarker: identification of SARC-CoV-2 related protein(s) in Serum Extracellular Vesicles
link.springer.com/article/10.1...
link.springer.com/article/10.1...
~10 mya fossilized whale bone i found on the beach this week
June 21, 2026 at 12:01 AM
~10 mya fossilized whale bone i found on the beach this week
Want to know how many vesicles there are in a mossy fibre synapse, without counting thousands of vesicles by hand in electron micrographs?
Our new tool SynapseNet has you covered and is now available as a preprint www.biorxiv.org/content/10.1... .
Read on for a short overview of our paper.
Our new tool SynapseNet has you covered and is now available as a preprint www.biorxiv.org/content/10.1... .
Read on for a short overview of our paper.
December 6, 2024 at 3:39 PM
Want to know how many vesicles there are in a mossy fibre synapse, without counting thousands of vesicles by hand in electron micrographs?
Our new tool SynapseNet has you covered and is now available as a preprint www.biorxiv.org/content/10.1... .
Read on for a short overview of our paper.
Our new tool SynapseNet has you covered and is now available as a preprint www.biorxiv.org/content/10.1... .
Read on for a short overview of our paper.
FULLY cosigned.
Like, God is a man? Really? Your unknowable, inscrutable, all powerful and everlasting creator of the known universe has a penis and balls? He produces god-sperm in his holy little seminal vesicles? And you’ve decided to be weirdly adamant about that?
Like, God is a man? Really? Your unknowable, inscrutable, all powerful and everlasting creator of the known universe has a penis and balls? He produces god-sperm in his holy little seminal vesicles? And you’ve decided to be weirdly adamant about that?
*whispers*
The idea that God is GENDERED is actually the really creepy position to take.
The idea that God is GENDERED is actually the really creepy position to take.
May 27, 2026 at 5:22 PM
FULLY cosigned.
Like, God is a man? Really? Your unknowable, inscrutable, all powerful and everlasting creator of the known universe has a penis and balls? He produces god-sperm in his holy little seminal vesicles? And you’ve decided to be weirdly adamant about that?
Like, God is a man? Really? Your unknowable, inscrutable, all powerful and everlasting creator of the known universe has a penis and balls? He produces god-sperm in his holy little seminal vesicles? And you’ve decided to be weirdly adamant about that?
your golgi apparatus isn’t even packaging proteins and lipids into vesicles you piece of shit
March 29, 2026 at 7:41 PM
your golgi apparatus isn’t even packaging proteins and lipids into vesicles you piece of shit
Are you studying synapses in electron microscopy? Tired of annotating vesicles? We have the tool for you! SynapseNet implements automatic segmentation and analysis of vesicles and other synaptic structures and has now been published:
www.molbiolcell.org/doi/full/10....
www.molbiolcell.org/doi/full/10....
October 17, 2025 at 11:09 AM
Are you studying synapses in electron microscopy? Tired of annotating vesicles? We have the tool for you! SynapseNet implements automatic segmentation and analysis of vesicles and other synaptic structures and has now been published:
www.molbiolcell.org/doi/full/10....
www.molbiolcell.org/doi/full/10....
In situ visualization of autophagy reveals the presence of vesicles at the expanding phagophore rim pubmed.ncbi.nlm.nih.gov/42781864/ #cryoem
September 25, 2026 at 2:50 PM
In situ visualization of autophagy reveals the presence of vesicles at the expanding phagophore rim pubmed.ncbi.nlm.nih.gov/42781864/ #cryoem
Cell-to-cell cooperation through membrane vesicles enhances antibiotic persistence @science.org @bcmfromthelabs.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
June 25, 2026 at 7:03 PM
Cell-to-cell cooperation through membrane vesicles enhances antibiotic persistence @science.org @bcmfromthelabs.bsky.social
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
I've written a review on what I think is an extremely exciting direction in cryo-EM:
Cryo-EM of endogenous membrane proteins in their native lipid bilayer
Open access in Quarterly Reviews of Biophysics:
doi.org/10.1017/S003...
Cryo-EM of endogenous membrane proteins in their native lipid bilayer
Open access in Quarterly Reviews of Biophysics:
doi.org/10.1017/S003...
March 6, 2026 at 12:40 PM
I've written a review on what I think is an extremely exciting direction in cryo-EM:
Cryo-EM of endogenous membrane proteins in their native lipid bilayer
Open access in Quarterly Reviews of Biophysics:
doi.org/10.1017/S003...
Cryo-EM of endogenous membrane proteins in their native lipid bilayer
Open access in Quarterly Reviews of Biophysics:
doi.org/10.1017/S003...
#vss365 (dissolve) #poetry #haiku #blueskypoet #flowers #bloomscrolling #bee
Sipping liquid ambrosia
Dissolved in small vesicles
Around the globe
Sipping liquid ambrosia
Dissolved in small vesicles
Around the globe
May 13, 2025 at 12:24 AM
#vss365 (dissolve) #poetry #haiku #blueskypoet #flowers #bloomscrolling #bee
Sipping liquid ambrosia
Dissolved in small vesicles
Around the globe
Sipping liquid ambrosia
Dissolved in small vesicles
Around the globe
Cool new study showing glycoRNAs on circulating extracellular vesicles may have diagnostic utility #glycotime
Advancing #glycoRNA imaging with FRET-based detection and expanding the scope of their presentation to extracellular vesicles - interestingly high levels of sialoglycoRNAs on blood EVs can be predictive of having cancer @naturecomms.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com
April 11, 2025 at 3:16 PM
Cool new study showing glycoRNAs on circulating extracellular vesicles may have diagnostic utility #glycotime
The physico-chemical landscape of extracellular vesicles
"Extracellular vesicles seem to be released by all cell types and can transport bioactive molecules between cells, tissues, organs and organisms."
www.nature.com/articles/s44...
"Extracellular vesicles seem to be released by all cell types and can transport bioactive molecules between cells, tissues, organs and organisms."
www.nature.com/articles/s44...
The physico-chemical landscape of extracellular vesicles - Nature Reviews Bioengineering
Extracellular vesicles are being explored for various biomedical applications, but face challenges with regard to isolation, characterization and manufacturing. This Review delineates the physico-chem...
www.nature.com
December 14, 2024 at 10:37 AM
The physico-chemical landscape of extracellular vesicles
"Extracellular vesicles seem to be released by all cell types and can transport bioactive molecules between cells, tissues, organs and organisms."
www.nature.com/articles/s44...
"Extracellular vesicles seem to be released by all cell types and can transport bioactive molecules between cells, tissues, organs and organisms."
www.nature.com/articles/s44...
Excited our Large Extracellular Vesicles/Midbody Remnants generated during the cell cycle is out! #ev #mbrs #extracellularvesicles #cellcycle #mitosis
www.molbiolcell.org/doi/10.1091/...
www.molbiolcell.org/doi/10.1091/...
December 3, 2024 at 3:36 PM
Excited our Large Extracellular Vesicles/Midbody Remnants generated during the cell cycle is out! #ev #mbrs #extracellularvesicles #cellcycle #mitosis
www.molbiolcell.org/doi/10.1091/...
www.molbiolcell.org/doi/10.1091/...
All along we've thought that aged white blood cells (neutrophils) promote inflammation and were detrimental. Now there's a discovery of aged neutrophils with Large AgingNeutrophil-Derived Vesicles (LAND-Vs)that are anti-inflammatory and help clear bacteria
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
March 20, 2025 at 5:07 PM
All along we've thought that aged white blood cells (neutrophils) promote inflammation and were detrimental. Now there's a discovery of aged neutrophils with Large AgingNeutrophil-Derived Vesicles (LAND-Vs)that are anti-inflammatory and help clear bacteria
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...