#osteocytes
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shahfa.bsky.social
🦴🔬🧪 #Osteocytes in #bone around an osseointegrated titanium #implant

Osteocytes are mechanosensory cells that form a neuron-like network within bone and can regulate bone remodelling.

pubs.acs.org/doi/full/10....

#biomineralization #biology #orthopaedics #science #electronmicroscopy #imaging
This is a scanning electron microscopy image of osteocytes clinging to the surface of a titanium implant that has been surface modified by selective laser ablation to create a hierarchical, macro-micro-nano topography: https://pubs.acs.org/doi/full/10.1021/ab500127y The imaging technique is called Resin Cast Etching: https://link.springer.com/article/10.1007/s00223-022-01058-9
December 3, 2024 at 10:18 AM
shahfa.bsky.social
#Grogu spotted in #bone!

🦴🔬🧪🩻

#yoda #babyyoda #starwars #science #sciencefiction #imaging #microscopy #electronmicroscopy #biomineralization #osteocytes
December 22, 2024 at 3:28 PM
shahfa.bsky.social
🧪🔬🦴 This is an #Osteocyte

It lives in #bone and reaches out to #implants and #biomaterials through cellular extensions [ * ]

It frequently talks to other osteocytes and orchestrates bone remodelling

Be like the Osteocyte =)

* Scanning electron microscopy
** Horizontal field width = 27 µm
This is an Osteocyte. It lives in bone and reaches out to implants and biomaterials through cellular extensions [ * ]. It frequently talks to other osteocytes and orchestrates bone remodelling. Be like the Osteocyte!
December 10, 2024 at 3:59 PM
shahfa.bsky.social
🦴🔬🩻🧪🥼 Last #imaging session for 2024. Looking at some #bone using an environmental scanning electron microscope! See you again in 2025!

#microscopy #bioimaging #electronmicroscopy #biomineralization #collagen #apatite #osteocytes
December 22, 2024 at 1:25 PM
sarahmackattack.bsky.social
Yara went to museum collections and scanned a bunch of really old fish.

There is evidence for remodeling! How are they doing this without all the newfangled cells?! We dunno.

Cool.

#SICB2025
Goofy old fish whose name I forget but who has big silly googley eyes and a triangle mouth says “lol idk” in response to the question how am I remodeling without osteocytes?
January 4, 2025 at 2:50 PM
biogeoverse.bsky.social
Yara Haridy on Ordivician vertebrates and the origin of bone remodeling:

Synchrotron scanning tech really shines when used with tiny fossils such as those from jawless fish. This includes bony scales on the body of Astraspis.

Investigation shows bone remodeling predates osteocytes!

#2025SVP
November 12, 2025 at 9:02 AM
shahfa.bsky.social
🦴 A picture is worth a thousand words—but this one speaks of #bone formation, remodelling, repair, and renewal!

The small white/grey dots are #osteocytes

🔬 Scanning electron microscopy after resin cast etching
🔍 rdcu.be/ebD4R

#biomaterials #biomineralization #microscopy #electronmicroscopy 🧪
February 28, 2025 at 7:41 AM
hessofarhan.bsky.social
Our review on the role of ER proteostasis in bone disease is out today in Trends in Molecular Medicine www.cell.com/trends/molec...
The endoplasmic reticulum proteostasis network and bone disease
Bone homeostasis relies on the coordinated activity of osteoblasts and osteoclasts that balances bone formation and resorption, and of osteocytes for biomechanical sensing and hormone secretion. A key...
www.cell.com
July 11, 2025 at 9:22 AM
arctomet.bsky.social
B.J.N. Long et al. (2025)
Resonance Raman confirms partial haemoglobin preservation in dinosaur remains
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences 481(2321): 20250175
doi: doi.org/10.1098/rspa...
royalsocietypublishing.org/doi/10.1098/...
Resonance Raman confirms partial haemoglobin preservation in dinosaur remains | Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
Still soft, hollow, flexible structures morphologically consistent with blood vessels, vascular contents, cells (osteocytes) and collagenous matrix were recovered from demineralized bone of a number o...
doi.org
September 10, 2025 at 1:30 PM
acr-journals.bsky.social
March A&R Clinical Connections
•Evidence of Site-Specific Mucosal Autoantibody Secretion in Rheumatoid Arthritis
•Targeting Long Noncoding RNA H19 in Subchondral Bone Osteocytes and Alleviation of Cartilage Degradation in Osteoarthritis
acr.tw/3XjPdUS
#Medsky
Evidence of Site-Specific Mucosal Autoantibody Secretion in Rheumatoid Arthritis Targeting Long Noncoding RNA H19 in Subchondral Bone Osteocytes and Alleviation of Cartilage Degradation in Osteoarthritis
March 2, 2025 at 10:38 PM
nakamuralab.bsky.social
Very high resolution study of osteocytes in ancient fishes! Such intricate osteocytes network and low mineralized regions we can see!! www.science.org/doi/10.1126/...
Bone metabolism and evolutionary origin of osteocytes: Novel application of FIB-SEM tomography
New applications of imaging technology reveal that 425 million–year–old fossil bone cells had modern mineral metabolism abilities.
www.science.org
February 20, 2025 at 3:06 AM
biorxiv-microbiol.bsky.social
Chronic Staphylococcus aureus infection of osteocytes promotes an intracellular viable-but-non-culturable phenotype https://www.biorxiv.org/content/10.1101/2024.12.17.629047v1
January 2, 2025 at 3:16 PM
danielleri.bsky.social
Stuff like this truly helps one remember the many, MANY things you need to memorize in anatomy and physiology tbh (also, hey, anybody with the right connections want to see if osteocytes inspired metroid design? Eh?)
November 14, 2025 at 10:59 PM
shahfa.bsky.social
🦴🔬#Osteocyte – the master orchestrator of #bone #remodeling. ~42 billion in the average adult human skeleton, #osteocytes make up ~90–95% of all #cells within bone, interconnected by ~3.7 trillion dendritic projections with an estimated, total end-to-end length of 175,000 km 🔍
December 28, 2023 at 11:55 PM
samstehbens.bsky.social
Osteocytes also have a nuclear envelope #MTOC. #cytoskeleton
bpodaily.bsky.social Biomedical Picture of the Day BPoD @bpodaily.bsky.social · Apr 30
Structure of microtubules around the osteoclast nuclear envelope influences their bone resorption function

📸 Silvia Vergarajauregui et al Friedrich-Alexander-Universität Erlangen-Nürnberg in @jcellsci.bsky.social

➡️ bpod.org.uk/archive/2026...
BPoD | Solving Bone Dissolving
Solving Bone Dissolving - Biomedical pictures for April 2026.
bpod.org.uk
May 1, 2026 at 11:03 AM
idontevencara.bsky.social
This is thought to be the mechanism your osteocytes cue on to ramp up bone production. And external vibration at just the right frequency can drive huge changes; I’ve written about resonances before:
bsky.app/profile/idon...

5/7
idontevencara.bsky.social Cara Giovanetti @idontevencara.bsky.social · Oct 19
Neurons in your brain are also coupled—not by springs, but by electrical and chemical signals in synapses. When one neuron fires, its effect can be felt nearby in the network. And if the neuron fires repeatedly, at just the right frequency, it can produce a large effect:

3/5
April 26, 2026 at 4:33 PM
natrevdiseaseprimers.nature.com
In osteomyelitis, bacteria interact with osteoclasts, osteoblasts and osteocytes, each showing distinct responses that influence bacterial behaviour and overall disease outcomes. http://dlvr.it/TSpXhG
A diagram listing the effects of bacterial interactions with bone cells in osteomyelitis.
June 1, 2026 at 1:35 AM
invertevo.bsky.social
X-ray analysis of bony scale fossils shows vertebrates developed ability to remodel and repair bone 460 Mya.

www.science.org/doi/10.1126/...
Bone metabolism and evolutionary origin of osteocytes: Novel application of FIB-SEM tomography
New applications of imaging technology reveal that 425 million–year–old fossil bone cells had modern mineral metabolism abilities.
www.science.org
January 12, 2025 at 5:33 PM
shahfa.bsky.social
🧪🔬🦴💠 A Review of the Impact of Implant Biomaterials on Osteocytes

journals.sagepub.com/doi/full/10....

#bone #biomaterials #osteocytes #microscopy #histology #electronmicroscopy #imaging #biology #science #aging #biomechanics #osteoporosis #bonehealth #pathology
The proximity of osteocytes (Ot) to implant surfaces observed with (a) histology and (b) BSE-SEM. (c) Resin cast etching allows visualization of osteocyte attachment to implant surfaces. (d) Osteocyte attachment to an acid-etched surface. (e) Interdigitation of canaliculi with the implant surface (arrowheads). (f, g) Canaliculi (Ot.Ca) adherent to the surface of a laser-ablated implant. (h) Cross-sectional view of canaliculi (*) in close association with surface TiO2 layer of a laser-ablated implant (HAADF-STEM). (i) Osteocytes align parallel to the lamellar direction, which closely follows the microcontour of the laser-ablated implant surface. (j) Adjacent to the implant surface, osteocytes form an interconnected network. (k) Canaliculi (arrowheads) can be identified within the first several micrometers from the implant surface (HAADF-STEM). (l) Mineralized collagen fibrils appear to “wrap around” the canaliculus (*).
May 12, 2024 at 3:01 PM
jafretz.bsky.social
Enjoy some gorgeous TRAP staining of osteoclasts (and a few osteocytes)
🧪
November 20, 2024 at 6:17 PM
natrevendo.nature.com
In this Review, Silvia Marino & Teresita Bellido discuss the role of the parathyroid hormone 1 receptor pathway in bone homeostasis and of osteocytes as mechanosensors and drivers of bone remodelling (£) go.nature.com/43fzOI0
Figure showing osteocytes as drivers of bone remodelling.
October 13, 2025 at 4:36 PM
fayereplicant.bsky.social
Painting, acrylic, paper. Abstract, emotional based on a poem I wrote. Words Like Katanas Humans wield words like katanas, Both intentionally And Unintentionally, Like a child’s scream in your ear, It pierces and cuts You to the core, Guts your spirit, Sashimis the heart, And Eviscerates the soul, Leaving you Broken yet whole. Words cut down deep, To the gelatinous juice, The spiderweb-like Hollow, Give last rites To the osteocytes, Honeycomb of matrix marrow. Words can leave you More ghoul than alive, Aimlessly wandering The land of unrequited lovers. Pennies on your eyes As you slurry along In the cursed Land, Holding your Bleeding katana, Eviscerated heart In your hands.
March 12, 2025 at 1:38 AM
paleogalli.bsky.social
Ressonância Raman confirma preservação parcial de hemoglobina em restos de dinossauros royalsocietypublishing.org/doi/10.1098/...
Resonance Raman confirms partial haemoglobin preservation in dinosaur remains | Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
Still soft, hollow, flexible structures morphologically consistent with blood vessels, vascular contents, cells (osteocytes) and collagenous matrix were recovered from demineralized bone of a number o...
royalsocietypublishing.org
September 10, 2025 at 9:39 AM