#gammadeltaTcells
Zhu, Xu, Caspi et al. show that Vγ6 γδ T cells sense commensals via TLR2 to fuel IL-17A-mediated barrier defense at the ocular surface. rupress.org/jem/article/...

#BarrierImmunity #OcularImmunity #GammaDeltaTCells
September 11, 2025 at 4:15 PM
Antibody Therapeutics (IF=4.5, Oxford University Press) ⚡ Research Highlight - "Novel ADC and γδ T cell engager targeting CDH17 for the therapy of gastrointestinal cancers"
doi.org/10.1093/abt/...
#antibody #antibodydrugconjugate #tcellengager #gammadeltatcells #immunotherapy
Novel ADC and γδ T cell engager targeting CDH17 for the therapy of gastrointestinal cancers
Statement of Significance We developed two novel complementary therapeutic modalities targeting an emerging gastrointestinal tumor-associated antigen, CDH1
doi.org
August 6, 2026 at 9:49 PM
Melanoma danger doesn’t follow a straight line—it peaks in middle age, not old age. New research shows protect the young and very old, but drop off in #GammaDeltaTCells #Melanoma #CancerRisk

https://freegardner.wordpress.com/2026/06/07/melanoma-danger-peaks-in-middle-age-not-old-age
Melanoma danger peaks in middle age not old age
Melanoma danger peaks in middle age not old age
freegardner.wordpress.com
June 7, 2026 at 1:37 PM
In @jem.org, Zhu, Xu, Caspi et al. show that Vγ6 γδ T cells sense commensals via TLR2 to fuel IL-17A-mediated barrier defense at the ocular surface. rupress.org/jem/article/...

#BarrierImmunity #OcularImmunity #GammaDeltaTCells
September 11, 2025 at 4:45 PM
TLR2 supports γδ T cell IL-17A response to ocular surface commensals by metabolic reprogramming, say Wenjie Zhu, Xiaoyan Xu, Rachel Caspi (National Eye Institute, NIH) and colleagues: rupress.org/jem/article/...

#BarrierImmunity #OcularImmunity #GammaDeltaTCells #MucosalImmunology
September 18, 2025 at 2:45 PM