#mini2p
My lab University College London is looking for an experimental postdoc to join our team. Interested in circuits underlying visually guided behavior, chronic #Neuropixel recordings or 2-photon imaging (Benchtop, #Mini2p)? Then check out our lab homepage www.ruedigerlab.com, apply & spread the word
November 22, 2024 at 7:09 AM
A half-century old question may have its final answer. Using high-resolution #Mini2P microscopes, we find no evidence of local topography in #PlaceCells. Place fields of neighbouring cells are no more similar than those of randomly selected cells. 🧠🗺️ Out now in @pnas.org www.pnas.org/doi/10.1073/...
Place cells in CA1 lack topographical organization of firing locations | PNAS
Topography is a well-described and well-known concept for cortical organization in primary sensory and motor cortices of mammalian brains. Similar ...
www.pnas.org
February 19, 2026 at 11:53 AM
The tool:
MINI2P is a miniature portable 2-photon miniscope for high-resolution multiplane imaging of thousands of neurons in the cortical tissue of freely moving mice: www.ntnu.edu/kavli/mini2p
The Mini2P - The Kavli Institute for Systems Neuroscience - NTNU
Mini2P is a the tiny brain explorer from the Kavli Institute.
www.ntnu.edu
January 15, 2025 at 2:29 PM
Mini2p whale imaging 🐳
January 8, 2025 at 12:25 PM
...meanwhile: comparison objective size 2pRAM vs. mini2p
January 8, 2025 at 11:32 AM
A miniature two-photon microscope #Mini2P
Congratulations to the brilliant Weijian Zong, who today received a FRIPRO grant by The Research Council of Norway for the miniature microscope #Mini2P, that allows researchers to see 👀 cognitive functions emerge from thousands of collaborating neurons in the brain 🧠 of a freely behaving mouse!
December 6, 2024 at 7:24 PM
Congratulations to the brilliant Weijian Zong, who today received a FRIPRO grant by The Research Council of Norway for the miniature microscope #Mini2P, that allows researchers to see 👀 cognitive functions emerge from thousands of collaborating neurons in the brain 🧠 of a freely behaving mouse!
December 5, 2024 at 6:57 PM
Congratulations to @weijianzong.bsky.social, our Neurophotonics group leader and a new 2026 #FENSKavliScholar.

He builds the #Mini2P microscopes that let us watch the living brain at work.

@fens.org @kavlifoundation.org @alleninstitute.org @ntnudiscovery.bsky.social @fkne-scholars.bsky.social
July 8, 2026 at 6:50 AM
2/6
To test this, we used #Mini2P 🔬 to image thousands of CA1 neurons simultaneously in freely moving mice 🐭
This allowed us to combine high anatomical precision with natural behavior.
February 20, 2026 at 12:17 PM
High-Speed Neural Imaging with Multiplexed Miniature Two-Photon Microscopy (M-MINI2P) https://www.biorxiv.org/content/10.1101/2025.03.04.641573v1
March 10, 2025 at 6:20 PM
Shocking news! I got a FRIPRO grant by the Research Council of Norway. Lots of thanks to my institute @kavlintnu.bsky.social, my mentors and my lab members for the support! Contact me if you want to join us developing cool miniature microscopes #Mini2P for studying exciting neuroscience questions!
December 5, 2024 at 10:18 PM
Always sad to leave MBL after our cycle at NS&B is over! We had an awesome time doing mini2p imaging with a @thorlabs.bsky.social system to look at cortical neurons in freely moving animals. Can't even see the scope in the lab pic, tiny but powerful! 💪🔬🐭 @nsb-mbl.bsky.social @mhigley.bsky.social
June 22, 2026 at 10:59 PM
Thank @kavlintnu.bsky.social, the research council of Norwayfor the continues support of our work! We will provide more useful tools like #mini2p to the neuroscience!
October 31, 2025 at 4:48 PM
Excited to be here at the @mpfneuro.bsky.social #Sunposium26 where we are demonstrating our Mini2P with Spark Lasers.
If you're nearby, visit us at booth 102!🔬
March 10, 2026 at 6:51 PM
#mini2P

🔥 NEW! Pair the compact, fixed-wavelength Axon FL from Coherent with any brand of miniaturized multiphoton microscope.

🚀 Resolve calcium signals in axons, dendrites, and spines — in the 🧠 of freely moving 🐭.

💬 Let’s talk options for your application!

www.coherent.com/news/press-r...
Axon FL: A Versatile Fiber Coupling Module for Mini2P Applications
Apr. 18, 2025. Coherent announces the launch of the Axon F.
www.coherent.com
May 1, 2025 at 1:01 PM
Congrats to Weijian Zong! Weijian and the #Mini2P team have had an amazing 2024 and this is just another feather in their cap!
Congratulations to the brilliant Weijian Zong, who today received a FRIPRO grant by The Research Council of Norway for the miniature microscope #Mini2P, that allows researchers to see 👀 cognitive functions emerge from thousands of collaborating neurons in the brain 🧠 of a freely behaving mouse!
December 5, 2024 at 9:58 PM
We are excited to partner with the @mpfneuro.bsky.social to advance brain research through cutting-edge imaging technology!

This collaboration brings our Mini2P two-photon microscope and other advanced imaging systems to MPFI, enabling researchers to observe neural activity in unprecedented detail.
We are excited to announce a new partnership with @thorlabs.bsky.social that will give our researchers access to groundbreaking new Mini2P imaging. Read more about the Thorlabs Innovation Center at MPFI & how it will allow scientists to see neural activity in unprecedented detail:🔬 buff.ly/rdRbRfG
March 27, 2025 at 1:36 PM
At #FENS2026 next week? Welcome to Zong Lab presentations to hear how we are developing and applying new generations of #mini2P to understand the neuronal algorithms in the brain. We will give 1 oral talk and three poster presentations! Come and check out😊
July 3, 2026 at 9:54 AM
The project:
You will apply our recently developed cutting-edge MINI2P to monitor and manipulate neural activity in naturally-behaving animals to uncover and decipher neuronal computation rulesets in cortical microcircuits.
January 15, 2025 at 2:29 PM
We are hiring two enthusiastic and highly motivated candidates for a PhD position or postdoctoral fellowship to work on model-driven systems neuroscience using MINI2P.

Please apply here: www.jobbnorge.no/en/available...
PhDs and/or postdocs (272467) | NTNU - Norwegian University of Science and Technology
Job title: PhDs and/or postdocs (272467), Employer: NTNU - Norwegian University of Science and Technology, Deadline: Sunday, March 2, 2025
www.jobbnorge.no
January 15, 2025 at 2:29 PM
We are excited to announce a new partnership with @thorlabs.bsky.social that will give our researchers access to groundbreaking new Mini2P imaging. Read more about the Thorlabs Innovation Center at MPFI & how it will allow scientists to see neural activity in unprecedented detail:🔬 buff.ly/rdRbRfG
March 27, 2025 at 1:02 PM
META2P will bridge neurotech and nanotech to enable high-resolution calcium imaging across multiple brain regions in freely moving animals. This could redefine how we study brain function, behaviour, and disease.

🚀 From MINI2P to META2P – pushing the frontier of in vivo neuroscience imaging.
December 19, 2025 at 3:00 PM
hmm. I worry more about that with Caiman and demixing… But we currently do not denoise. We have pretty noisy mini2p data currently that may benefit, though.
January 8, 2025 at 10:57 AM
In a new study out in @pnas.org, the #MoserGroup recorded thousands of neurons in the #hippocampus of freely moving mice using #Mini2P and asked a simple question: Is the brain’s internal map laid out in the same orderly way as physical space, where nearby cells represent nearby locations?
February 19, 2026 at 11:59 AM
Me: Can I get a Dr. House?
Mom: We have a Dr. House at home
The Dr. House at home:

(It me, I sprained my ankle)
November 17, 2025 at 10:54 PM