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Researchers have developed a groundbreaking microscopy method that enables detailed three-dimensional (3D) RNA analysis at cellular resolution in whole intact mouse brains. The new method, called TRIS...

MBF Bioscience is excited to announce that NeuroInfo now supports two developmental mouse brain atlases from the Kim Lab. These atlases...

Knowledge of the brain’s immune system has come a long way since scientists thought the brain was completely cut off from the body’s defenses. Now, using a technique called mass cytometry, researchers have characterized the diverse populations of immune cells in the mouse brain—and there are a lot of them. Scientists led by Asya Rolls, Israel Institute of Technology, Haifa, report in the July 24 Nature Neuroscience that microglia keep company with B cells, T cells, and natural killer cells. Some were expected in the normal brain, but others were a complete surprise. This study catalogues which immune cells inhabit the healthy mouse brain, where they reside, and where they originated. It provides the basis for similar future analyses in models of stress, infection, or neurodegeneration, to see how immune cells factor in to those conditions.