#multipleximaging
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cellima-science.bsky.social
Five-color SR in one shot — strong step toward scalable multiplexed phenotyping.
Next challenge: 3D + live-cell stability.

#SPSTORM #MultiplexImaging #HCI
High Throughput Hyperspectral and Multiplexed Super-Resolution Fluorescence Imaging by SP-STORM | Stefan Prechtl
𝗦𝗣-𝗦𝗧𝗢𝗥𝗠 (𝗦𝗽𝗲𝗰𝘁𝗿𝗮𝗹-𝗣𝗵𝗮𝘀𝗼𝗿 𝗦𝗧𝗢𝗥𝗠) 𝘗𝘳𝘦𝘗𝘳𝘪𝘯𝘵 𝘸𝘰𝘳𝘵𝘩 𝘢 𝘭𝘰𝘰𝘬 “𝗛𝗶𝗴𝗵 𝗧𝗵𝗿𝗼𝘂𝗴𝗵𝗽𝘂𝘁 𝗛𝘆𝗽𝗲𝗿𝘀𝗽𝗲𝗰𝘁𝗿𝗮𝗹 𝗮𝗻𝗱 𝗠𝘂𝗹𝘁𝗶𝗽𝗹𝗲𝘅𝗲𝗱 𝗦𝘂𝗽𝗲𝗿-𝗥𝗲𝘀𝗼𝗹𝘂𝘁𝗶𝗼𝗻 𝗙𝗹𝘂𝗼𝗿𝗲𝘀𝗰𝗲𝗻𝗰𝗲 𝗜𝗺𝗮𝗴𝗶𝗻𝗴 𝗯𝘆 𝗦𝗣-𝗦𝗧𝗢𝗥𝗠” (𝘗𝘰𝘵𝘵 𝘦𝘵 𝘢𝘭., 𝘣𝘪𝘰𝘙𝘹𝘪𝘷, 𝘚𝘦𝘱𝘵 2025 — https://lnkd.in/d5smSTUN ) A clever implementation of spectral-phasor analysis directly in hardware — achieving simultaneous five-color super-resolution imaging within about a minute. By merging sine/cosine filter optics with dSTORM principles, the method reduces spectral crosstalk (<5 %) and removes the need for sequential channel switching. The hardware-level multiplexing is a decisive step toward practical multi-target SMLM, though the current proof remains 2D and relies on custom filter sets. 𝘈 𝘵𝘢𝘯𝘨𝘪𝘣𝘭𝘦 𝘢𝘥𝘷𝘢𝘯𝘤𝘦 𝘪𝘯 𝘮𝘶𝘭𝘵𝘪𝘱𝘭𝘦𝘹𝘦𝘥 𝘱𝘩𝘦𝘯𝘰𝘵𝘺𝘱𝘪𝘯𝘨 — 𝘰𝘯𝘦 𝘵𝘩𝘢𝘵 𝘤𝘰𝘶𝘭𝘥 𝘳𝘦𝘴𝘩𝘢𝘱𝘦 𝘩𝘰𝘸 𝘴𝘱𝘦𝘤𝘵𝘳𝘢𝘭 𝘪𝘯𝘧𝘰𝘳𝘮𝘢𝘵𝘪𝘰𝘯 𝘪𝘴 𝘪𝘯𝘵𝘦𝘨𝘳𝘢𝘵𝘦𝘥 𝘪𝘯𝘵𝘰 𝘏𝘊𝘐 𝘸𝘰𝘳𝘬𝘧𝘭𝘰𝘸𝘴 𝘰𝘯𝘤𝘦 𝘴𝘤𝘢𝘭𝘦𝘥 𝘵𝘰 𝟥𝘋 𝘢𝘯𝘥 𝘭𝘪𝘷𝘦 𝘪𝘮𝘢𝘨𝘪𝘯𝘨. #SPSTORM #SpectralImaging #SMLM #Multiplex #HighContent #FluorescenceMicroscopy #bioRxiv
www.linkedin.com
October 23, 2025 at 8:36 AM
dreugenemanleyjr.bsky.social
Dr. Christopher Kunney At Iotech Consulting Moderated our #AI in Screening and Detection with Drs. Ameen Salahudeen @uicancercenter.bsky.social and Lecia Sequist at MGH. They talked about #bias, #ML, drift, #multipleximaging, and #SYBIL in #lungcancer. #LCSM #LDCT #LCHES24 #SCHEQ
November 23, 2024 at 8:51 PM
hamamatsucorp.bsky.social
We’re excited to announce a strategic collaboration pairing Biocare Medical’s ONCORE Pro X™ automated staining instrument with our MoxiePlex™ multispectral imaging system. Learn more about our partnership: https://ow.ly/RI8h50XlcqN

#SpatialBiology #MultiplexImaging #CancerResearch
November 4, 2025 at 6:55 PM
rarecyte.bsky.social
Spatial characterization of immune cells within a NSCLC tumor. 🔬 Image courtesy of Courtney Todorov, @neogenomics.bsky.social. Image taken on the CyteFinder II Instrument.

➡️ View all images from RareCyte's 2025 Calendar Contest, rarecyte.com/imagecontest/

#MultiplexImaging #Immunofluorescence
January 14, 2025 at 7:49 PM
rarecyte.bsky.social
Beautiful Orion images from Simon Goldstein, La Jolla Institute for Immunology (@lji.org)! Thrilled to feature both images in our 2025 calendar. 🎉

🟣 Mouse ileum spiral
🔵 Human lung tumor with dense immune aggregates

#SpatialBiology #MultiplexImaging #Florescence
lji.org La Jolla Institute for Immunology (LJI) @lji.org · Jan 13
#Microscopy gives us an absolutely breathtaking view of the immune system 😍

A huge congratulations to LJI's Simon Goldstein and the LJI Microscopy and Histology Core for having TWO stunning images featured in the 2025 @rarecyte.bsky.social Calendar rarecyte.com/imagecontest/ #immunology #biology
Orion 15 channel imaging of a normal murine ileum spiral. Courtesy of Simon Goldstein, La Jolla Institute for Immunology. The image shows the wavy lining of the ileum, with finger-like villa reaching out. Cells are highlighted with green, purple, pink, and blue florescent markers. Orion 18 channel imaging of a human lung tumor with dense immune aggregates. Courtesy of Simon Goldstein, La Jolla Institute for Immunology. Image shows cells against a background. Cells are highlighted with green, yellow, blue, and pink florescent markers. The image appears abstract, with clumps of cells forming loose swirls of color.
January 13, 2025 at 9:58 PM
rarecyte.bsky.social
✨ Image Spotlight: 17-channel imaging of Pancreas Ductal Adenocarcinoma using the Orion Platform. Image courtesy of Estefania Quesada Masachs, U Miami.

View the whole slide image and biomarker panel for this sample: images.rarecyte.com/Q131-pancreas

#SpatialBiology #MultiplexImaging #RareCyte
January 13, 2025 at 5:04 PM
granuccilab.bsky.social
✨ That’s a wrap on The Power of Multiplexed Imaging!
A full week of hands-on sessions, inspiring lectures, a great seminar, and data analysis!
Huge thanks to all participants for your energy. Can’t wait for the next edition — stay tuned! 🔬🌈
#MultiplexImaging #SpatialBiology
July 5, 2025 at 10:02 AM
granuccilab.bsky.social
✨ Reminiscing about last year’s multiplexed imaging course—such a fantastic experience! 🤩 We were thrilled to have @colinchulab.bsky.social, along with all the students & guests! Truly inspiring days of learning. Big things coming—stay tuned! 👀🚀🔬 #SpatialBiology #MultiplexImaging
March 7, 2025 at 4:28 PM
eksiece.bsky.social
opening new avenues for understanding the tumor microenvironment. Congratulations to first author Kaoutar Ait-Ahmad and the stellar multiplex imaging team at OHSU! #cancerneuroscience #prostatecancer #spatialprofiling #multipleximaging #neuronalinnervation
December 19, 2024 at 6:14 PM
jrmansfield.bsky.social
Webinar: Bridging the Gap: Insights from Mouse and Human Models in Pancreatic Cancer Research. Guest Speaker: Marco Erreni, Ph D, Humanitas Milano

my.demio.com/ref/qABk0lBp...

#PDAC #SpatialBio #IMC #Multipleximaging #SpatialProteomics @standardbiology.bsky.social
Bridging the Gap: Insights from Mouse and Human Models in Pancreatic Cancer Research
Guest Speaker: Marco Erreni, Ph D, Humanitas Research Hospital
my.demio.com
January 12, 2025 at 4:13 PM
jrmansfield.bsky.social
Wow! What a big day for #multipleximaging and #spatialbio! I am proud to have played a role in the genesis of this field in I-O. And more to come! @standardbiology.bsky.social
December 7, 2024 at 2:29 AM