#pathogenicity
It’s nothing new. Viruses and bacteria have been known to wax and wane wrt pathogenicity for ages. Acquiring and losing “pathogenicity factors”.
January 26, 2026 at 3:07 PM
Seriously, if you have access to ProQuest, you can read how the "Pretty Fly for a White Guy" dude helped cure AIDS www.proquest.com/docview/2071...
Discovery of Mature MicroRNA Sequences within the Protein-Coding Regions of Global HIV-1 Genomes: Predictions of Novel Mechanisms for Viral Infection and Pathogenicity - ProQuest
Explore millions of resources from scholarly journals, books, newspapers, videos and more, on the ProQuest Platform.
www.proquest.com
August 1, 2025 at 1:57 PM
For months now, the CDC has described H5N1 as “mild” compared to prior H5N1 viruses. I disagree—the virus alone doesn’t determine pathogenicity.

I hypothesize that the 2 most critical determinants of H5N1 severity are the host (it’s always the host 🥰) & the route of infection.
Louisiana released a bit more information late today about the person who contracted #H5N1 #birdflu from a backyard poultry flock. The individual is in critical condition. Over age 65. Has health conditions that make him or her at higher risk of bad illness from #flu.
#CDC has confirmed an #H5N1 #birdflu case in Louisiana, in a person believed to have been infected through contact with infected birds in a backyard flock. This person is seriously ill, the first such case recorded in the US. Similarities to the recent BC case. www.statnews.com/2024/12/18/h...
December 19, 2024 at 2:07 PM
Excited to announce the upcoming 2026 Microbial Toxins and Pathogenicity GRC and GRS meeting taking place July 12 - 17, 2026 at Waterville Valley in New Hampshire. This meeting will be chaired by yours truly and co-chaired by
@sunnyshinlab.bsky.social www.grc.org/microbial-to...
2026 Microbial Toxins and Pathogenicity Conference GRC
The 2026 Gordon Research Conference on Microbial Toxins and Pathogenicity will be held in Waterville Valley, New Hampshire. Apply today to reserve your spot.
www.grc.org
January 24, 2026 at 1:57 PM
New paper: Bird flu H5N1 may be closer to spreading between people than we previously realized.

It's able to enter cells from human upper airways, and it transmitted between ferrets, albeit inefficiently.
Pathogenicity and transmissibility of bovine H5N1 influenza virus - Nature
Nature - Pathogenicity and transmissibility of bovine H5N1 influenza virus
www.nature.com
July 8, 2024 at 5:53 PM
Early onset rapidly progressive frontotemporal dementia due to a novel MAPT P301A variant with functional validation of pathogenicity www.nature.com/articles/s44...

#FTD #MAPT #science #neuroscience #NeuroSkyenve
Early onset rapidly progressive frontotemporal dementia due to a novel MAPT P301A variant with functional validation of pathogenicity - npj Dementia
npj Dementia - Early onset rapidly progressive frontotemporal dementia due to a novel MAPT P301A variant with functional validation of pathogenicity
www.nature.com
June 1, 2026 at 7:14 PM
My daughter is officially a published scientist! Nature Microbiology, bitches!!!
February 27, 2026 at 5:00 PM
The study has been released as a pre-print and awaits peer review - but none the less provides insight into another, often overlooked, mode of virus transmission.

www.biorxiv.org/content/10.1...
Genetic data and meteorological conditions: unravelling the windborne transmission of H5N1 high-pathogenicity avian influenza between commercial poultry outbreaks
Understanding the transmission routes of high-pathogenicity avian influenza (HPAI) is crucial for developing effective control measures to prevent its spread. In this context, windborne transmission, ...
www.biorxiv.org
February 17, 2025 at 1:57 AM
One thing that comforts me in the current era is that, despite everything, really cool science continues to be published:

www.science.org/doi/10.1126/...

This could be a breakthrough for managing so many autoimmune diseases (still, in mice—don't get too excited).
Adenosine 2A receptor–dependent activation of AMPK represses TH17 cell pathogenicity through epigenetic and metabolic reprogramming
Epigenetic reprogramming that promotes oxidative metabolism suppresses TH17 cell pathogenicity.
www.science.org
September 24, 2025 at 8:48 PM
Near-absence of high pathogenicity avian influenza (HPAI) in Little Terns Sternula albifrons across 13 European countries | www.tandfonline.com/... | @birdstudy.bsky.social | #ornithology #seabirds 🪶
February 27, 2025 at 9:30 AM
"One USDA bird flu scientist kept a job but had to say goodbye to ... colleagues. “We all work on high pathogenicity avian influenza—seems like an absolutely reckless time to fire qualified scientists...directly involved in monitoring and responding to this virus right now,” the scientist wrote."
February 19, 2025 at 5:33 AM
Declines in UK breeding populations of seabird species of conservation concern following the outbreak of high pathogenicity avian influenza (HPAI) in 2021–2022 | www.tandfonline.com/... | Bird Study | #ornithology #seabirds #ukbirds 🪶
January 8, 2025 at 6:00 AM
Our article, a birder’s guide to HPAI, was published today in @britishbirds.bsky.social - it’s open access this month.

We explain how bird-flu infected seabirds in 2021/22 and the importance of citizen science to montoring future outbreaks in the wild. 🪶🧪

britishbirds.co.uk/journal/arti...
BB eye: A birder’s guide to High Pathogenicity Avian Influenza
High Pathogenicity Avian Influenza (HPAI, bird flu) virus infections have historically been most commonly associated with wild Eurasian waterfowl with...
britishbirds.co.uk
February 1, 2026 at 9:50 AM
Lifestyles shape genome size and gene content in fungal pathogens.
buff.ly/tec1Tds
November 2, 2025 at 11:01 AM
📅 Save the Date: Feb 24, 2025, at 11 AM CET! 🕚

Join our Virtual Micro-Symposium on Biofilms in Bacterial Pathogenicity, featuring insightful talks from Dr. Nicola Stanley-Wall and Dr. Jean-Marc Ghigo

🧫🔬 #Biofilms #Microbiology #Pathogenicity #VirtualEvent
November 13, 2024 at 5:33 AM
Researchers in #ScienceSignaling discovered a signaling mechanism that prevents T helper 17 cells from adopting pathogenic states linked to autoimmunity, potentially informing future efforts to treat autoimmune diseases such as multiple sclerosis.

Learn more on #WorldMSDay: https://scim.ag/49pMBuI
Adenosine 2A receptor–dependent activation of AMPK represses TH17 cell pathogenicity through epigenetic and metabolic reprogramming
Epigenetic reprogramming that promotes oxidative metabolism suppresses TH17 cell pathogenicity.
scim.ag
May 30, 2026 at 2:11 PM
The decisions were made quickly based on the incredibly fast actions of scientists.

MPI was notified Friday arvo. By Saturday evening the strain was identified as H7N6. It was not yet know whether it had high or low pathogenicity. By 8PM on Sunday it was know that it had high pathogenicity. 1/2
Country's first case of high pathogenic bird flu found on Otago egg farm
There are 40,000 chickens inside the shed where the high pathogenic bird flu has been identified.
www.rnz.co.nz
December 2, 2024 at 3:04 AM
Thrilled to share that the final chapter of my PhD with @rokaslab.bsky.social is now out in @natcomms.nature.com 🎉
Read it to find out how population structure impacts pathogenicity in Aspergillus flavus, a fungus that infects humans 🧪
rdcu.be/eAToj
Population structure in a fungal human pathogen is potentially linked to pathogenicity
Nature Communications - Genetic diversity between clinical and environmental fungal isolates of Aspergillus flavus is poorly studied. Here, the authors analysed genomic data from a global set of...
rdcu.be
August 18, 2025 at 9:48 PM
Significant decline of a Common Buzzard Buteo buteo population during an outbreak of high pathogenicity avian influenza (HPAI) | www.tandfonline.com/... | Bird Study | #ornithology #RaptorResearch 🪶
May 12, 2025 at 1:31 PM
I invited @systemsvirology.bsky.social to speak in the Systems Vaccinology session for his amazing work studying coronavirus emergence. Understanding emergence & pathogenicity informs vaccine design to prepare for pandemics. Also Kei is very cool & invites me to parties! 😎#19vaccinecongress
September 8, 2025 at 2:53 AM
Searching for high pathogenicity avian influenza virus in Antarctica

www.nature.com/articles/s41...
Searching for high pathogenicity avian influenza virus in Antarctica - Nature Microbiology
Nature Microbiology - Searching for high pathogenicity avian influenza virus in Antarctica
www.nature.com
November 20, 2024 at 7:12 PM
So what constitutes "gain-of-function research"? According to the bill, work involving influenza viruses, coronaviruses, and "Select Agents" that may be "reasonably anticipated" (whatever that means) to "enhanced infectivity, pathogenicity, or transmissibility [+'threat']".

But, there's more.
February 27, 2025 at 7:37 PM