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October 10, 2025 at 10:51 PM
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In patients needing coagulation factor replacement after cardiac surgery, prothrombin complex concentrate showed superior hemostatic effectiveness and fewer serious adverse events and acute kidney injuries compared to frozen plasma. #ACC25 https://ja.ma/43w3phs
March 29, 2025 at 4:50 PM
In patients needing coagulation factor replacement after cardiac surgery, prothrombin complex concentrate showed superior hemostatic effectiveness and fewer serious adverse events and acute kidney injuries compared to frozen plasma. #ACC25 https://ja.ma/43w3phs
Manifesting...
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June 22, 2026 at 11:45 PM
Manifesting...
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Prothrombin complex concentrate proved more effective and safer than frozen plasma for treating coagulopathic bleeding in cardiac surgery.
by Karkouti K, Callum JL (...) Levy JH et 33 al. in JAMA #MedSky
📖 read the article:
by Karkouti K, Callum JL (...) Levy JH et 33 al. in JAMA #MedSky
📖 read the article:
Prothrombin Complex Concentrate vs Frozen Plasma in Cardiac Surgery
This clinical trial compares the efficacy and safety of prothrombin complex concentrate with frozen plasma in patients requiring coagulation factor replacement for bleeding during cardiac surgery.
jamanetwork.com
April 7, 2025 at 6:41 AM
Prothrombin complex concentrate proved more effective and safer than frozen plasma for treating coagulopathic bleeding in cardiac surgery.
by Karkouti K, Callum JL (...) Levy JH et 33 al. in JAMA #MedSky
📖 read the article:
by Karkouti K, Callum JL (...) Levy JH et 33 al. in JAMA #MedSky
📖 read the article:
Congrats to Alex Feldman (my lab) & @reynarachel.bsky.social (Palumbo lab) on their hard-fought discovery of a role for prothrombin in preventing CD8 T cell-associated hemolytic anemia during virus infection in @jci-insight.bsky.social
@cincyresearch.bsky.social
insight.jci.org/articles/vie...
@cincyresearch.bsky.social
insight.jci.org/articles/vie...
January 17, 2025 at 5:18 PM
Congrats to Alex Feldman (my lab) & @reynarachel.bsky.social (Palumbo lab) on their hard-fought discovery of a role for prothrombin in preventing CD8 T cell-associated hemolytic anemia during virus infection in @jci-insight.bsky.social
@cincyresearch.bsky.social
insight.jci.org/articles/vie...
@cincyresearch.bsky.social
insight.jci.org/articles/vie...
What time is it?
February 9, 2026 at 2:46 AM
What time is it?
@labwaggoner.bsky.social @cincyresearch.bsky.social are the first to describe how liver protein prothrombin prevents fatal immunopathology during chronic virus infection in mice. buff.ly/A6szRmm
March 5, 2025 at 4:13 PM
@labwaggoner.bsky.social @cincyresearch.bsky.social are the first to describe how liver protein prothrombin prevents fatal immunopathology during chronic virus infection in mice. buff.ly/A6szRmm
Incredible. These people really have no new ideas. It's just recycling of trope after trope of points refuted a thousand times, as @aboutpediatrics.bsky.social says.
March 16, 2026 at 6:46 PM
Incredible. These people really have no new ideas. It's just recycling of trope after trope of points refuted a thousand times, as @aboutpediatrics.bsky.social says.
ICU studies:
In this *just published* unblinded RCT, prothrombin-complex concentrate (PCC) was found to have better efficacy than fresh frozen plasma (FFP) for management of excessive bleeding related to coagulation factor deficiency in patients undergoing cardiopulmonary bypass surgery
In this *just published* unblinded RCT, prothrombin-complex concentrate (PCC) was found to have better efficacy than fresh frozen plasma (FFP) for management of excessive bleeding related to coagulation factor deficiency in patients undergoing cardiopulmonary bypass surgery
March 31, 2025 at 1:18 AM
ICU studies:
In this *just published* unblinded RCT, prothrombin-complex concentrate (PCC) was found to have better efficacy than fresh frozen plasma (FFP) for management of excessive bleeding related to coagulation factor deficiency in patients undergoing cardiopulmonary bypass surgery
In this *just published* unblinded RCT, prothrombin-complex concentrate (PCC) was found to have better efficacy than fresh frozen plasma (FFP) for management of excessive bleeding related to coagulation factor deficiency in patients undergoing cardiopulmonary bypass surgery
Does Andexanet Alpha Improve Outcomes Compared With Four-Factor Prothrombin Complex Concentrate for Reversal of Direct Oral Anticoagulants? www.annemergmed.com/article/S019... #education #MedSky #MedTwitter #EMSky #EMedSky #BlueSky
November 22, 2024 at 1:37 AM
Does Andexanet Alpha Improve Outcomes Compared With Four-Factor Prothrombin Complex Concentrate for Reversal of Direct Oral Anticoagulants? www.annemergmed.com/article/S019... #education #MedSky #MedTwitter #EMSky #EMedSky #BlueSky
I had to search what is a PT test:
"Prothrombin Time Test and INR (PT/INR)
A prothrombin time (PT) test measures how many seconds it takes for a clot to form in a blood sample."
I agree this is a test that every alcoholic should do regularly.
"Prothrombin Time Test and INR (PT/INR)
A prothrombin time (PT) test measures how many seconds it takes for a clot to form in a blood sample."
I agree this is a test that every alcoholic should do regularly.
September 30, 2025 at 12:52 PM
I had to search what is a PT test:
"Prothrombin Time Test and INR (PT/INR)
A prothrombin time (PT) test measures how many seconds it takes for a clot to form in a blood sample."
I agree this is a test that every alcoholic should do regularly.
"Prothrombin Time Test and INR (PT/INR)
A prothrombin time (PT) test measures how many seconds it takes for a clot to form in a blood sample."
I agree this is a test that every alcoholic should do regularly.
Four-factor prothrombin complex concentrate proved superior in both hemostatic response & safety to frozen plasma for coagulation factor replacement for bleeding during cardiac surgery, according to FARES-II trial presented at #ACC25.
Read more: bit.ly/4iFMGNo
#CardioSky #MedSky
Read more: bit.ly/4iFMGNo
#CardioSky #MedSky
March 29, 2025 at 5:34 PM
Four-factor prothrombin complex concentrate proved superior in both hemostatic response & safety to frozen plasma for coagulation factor replacement for bleeding during cardiac surgery, according to FARES-II trial presented at #ACC25.
Read more: bit.ly/4iFMGNo
#CardioSky #MedSky
Read more: bit.ly/4iFMGNo
#CardioSky #MedSky
In patients needing coagulation factor replacement after cardiac surgery, prothrombin complex concentrate showed superior hemostatic effectiveness and fewer serious adverse events and acute kidney injuries compared to frozen plasma.
ja.ma/3ZxZFtd #MedSky
ja.ma/3ZxZFtd #MedSky
June 1, 2025 at 5:36 PM
In patients needing coagulation factor replacement after cardiac surgery, prothrombin complex concentrate showed superior hemostatic effectiveness and fewer serious adverse events and acute kidney injuries compared to frozen plasma.
ja.ma/3ZxZFtd #MedSky
ja.ma/3ZxZFtd #MedSky
Dr. Justine Ryu reveals new rare variants influencing VTE risk in carriers of Factor V Lieden (FVL) and Prothrombin Gene mutations #ASH24 @ash-hematology.bsky.social @yale-hematology.bsky.social @yalemed.bsky.social
December 7, 2024 at 8:28 PM
Dr. Justine Ryu reveals new rare variants influencing VTE risk in carriers of Factor V Lieden (FVL) and Prothrombin Gene mutations #ASH24 @ash-hematology.bsky.social @yale-hematology.bsky.social @yalemed.bsky.social
I'm sure I'll be fine with my COPD, Hypertension, Diabetes, and prothrombin gene mutation & subsequent predisposition to extra clotting.
August 7, 2025 at 2:55 AM
I'm sure I'll be fine with my COPD, Hypertension, Diabetes, and prothrombin gene mutation & subsequent predisposition to extra clotting.
4/ The INR Problem: INR is a mathematical manipulation of prothrombin time, measuring procoagulant factors (I, II, V, VII, X). However, it ignores deficits in anticoagulant factors, like protein C&S, also produced in the liver.
December 7, 2024 at 7:44 PM
4/ The INR Problem: INR is a mathematical manipulation of prothrombin time, measuring procoagulant factors (I, II, V, VII, X). However, it ignores deficits in anticoagulant factors, like protein C&S, also produced in the liver.
I mean he probably is getting regular almost daily blood work done.
June 2, 2026 at 6:36 PM
I mean he probably is getting regular almost daily blood work done.
🩺 #POSTER SAT-532 by Markus Maagaard et al. evaluated if direct #prothrombin concentration🩸can improve prognostic performance of the #MELD (Model for End-Stage Liver Disease) score in patients with decompensated #cirrhosis (compared to INR, the international normalised ratio).
@easlnews.bsky.social
@easlnews.bsky.social
May 31, 2026 at 12:23 PM
🩺 #POSTER SAT-532 by Markus Maagaard et al. evaluated if direct #prothrombin concentration🩸can improve prognostic performance of the #MELD (Model for End-Stage Liver Disease) score in patients with decompensated #cirrhosis (compared to INR, the international normalised ratio).
@easlnews.bsky.social
@easlnews.bsky.social
#IDSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social
Which of the following if normal would have the highest negative predictive value (NPV) for the cardiopulmonary phase of Hantavirus Pulmonary Syndrome?
A. Hemoglobin
B. Liver panel
C. Platelet count
D. Prothrombin time
Which of the following if normal would have the highest negative predictive value (NPV) for the cardiopulmonary phase of Hantavirus Pulmonary Syndrome?
A. Hemoglobin
B. Liver panel
C. Platelet count
D. Prothrombin time
January 26, 2025 at 5:18 PM
#IDSky @idsainfo.bsky.social @cidjournal.bsky.social @ofidjournal.bsky.social
Which of the following if normal would have the highest negative predictive value (NPV) for the cardiopulmonary phase of Hantavirus Pulmonary Syndrome?
A. Hemoglobin
B. Liver panel
C. Platelet count
D. Prothrombin time
Which of the following if normal would have the highest negative predictive value (NPV) for the cardiopulmonary phase of Hantavirus Pulmonary Syndrome?
A. Hemoglobin
B. Liver panel
C. Platelet count
D. Prothrombin time
📢JANUARY 2025 ISSUE🔔
TARGET: Personalised Management of #afib-Related Stroke with Health Virtual Twins Technology and #AI
Heterozygous Prothrombin Mutation #Thrombophilia
Prethrombin-1 as a Drug Promoting Hemostasis
Read more here ▶️ www.thieme-connect.com/products/ejo...
TARGET: Personalised Management of #afib-Related Stroke with Health Virtual Twins Technology and #AI
Heterozygous Prothrombin Mutation #Thrombophilia
Prethrombin-1 as a Drug Promoting Hemostasis
Read more here ▶️ www.thieme-connect.com/products/ejo...
January 22, 2025 at 10:12 AM
📢JANUARY 2025 ISSUE🔔
TARGET: Personalised Management of #afib-Related Stroke with Health Virtual Twins Technology and #AI
Heterozygous Prothrombin Mutation #Thrombophilia
Prethrombin-1 as a Drug Promoting Hemostasis
Read more here ▶️ www.thieme-connect.com/products/ejo...
TARGET: Personalised Management of #afib-Related Stroke with Health Virtual Twins Technology and #AI
Heterozygous Prothrombin Mutation #Thrombophilia
Prethrombin-1 as a Drug Promoting Hemostasis
Read more here ▶️ www.thieme-connect.com/products/ejo...
Text:
Q: Do you have any predictions about when a faulty Theranos test would have led to a death?
A: Theranos's faulty prothrombin time tests could easily have led to a death. For those unfamiliar with that test, it measures how fast your blood clots...
Q: Do you have any predictions about when a faulty Theranos test would have led to a death?
A: Theranos's faulty prothrombin time tests could easily have led to a death. For those unfamiliar with that test, it measures how fast your blood clots...
September 23, 2026 at 9:25 PM
Text:
Q: Do you have any predictions about when a faulty Theranos test would have led to a death?
A: Theranos's faulty prothrombin time tests could easily have led to a death. For those unfamiliar with that test, it measures how fast your blood clots...
Q: Do you have any predictions about when a faulty Theranos test would have led to a death?
A: Theranos's faulty prothrombin time tests could easily have led to a death. For those unfamiliar with that test, it measures how fast your blood clots...
I’m so deeply pharmacist that PCC only means prothrombin complex concentrate in my brain
April 18, 2025 at 12:33 AM
I’m so deeply pharmacist that PCC only means prothrombin complex concentrate in my brain
Study shows plasma prothrombin levels modulated in vivo podocyte health and function in a rat model of glomerular disease. https://bit.ly/JASN0676
#ASNJASN
#BasicResearch
@drklotter.bsky.social
#ASNJASN
#BasicResearch
@drklotter.bsky.social
April 27, 2025 at 7:00 PM
Study shows plasma prothrombin levels modulated in vivo podocyte health and function in a rat model of glomerular disease. https://bit.ly/JASN0676
#ASNJASN
#BasicResearch
@drklotter.bsky.social
#ASNJASN
#BasicResearch
@drklotter.bsky.social