#sinonasal
Delighted to share that I’ve been awarded the prestigious Polish-Czech Lead Agency Grant! 🎉Our project will explore how the sinonasal microbiota modulates airway immunity & allergic inflammation, in collaboration with Dr Sabina Górska. @mbuavcr.bsky.social #Nasalmicrobiome #Airways #Allergy #GAČR
July 14, 2025 at 6:50 PM
New publication: Characterization of Somatostatin Receptor 2 Gene Expression and Immune Landscape in Sinonasal Malignancies -
From multidisciplinary eam led by Drs Xue, Bracken-Clarke, Gulley, Floudas at the #NIH and Caris collaboration
www.mdpi.com/2072-6694/16...
@heloisasoares.bsky.social
Characterization of Somatostatin Receptor 2 Gene Expression and Immune Landscape in Sinonasal Malignancies
Olfactory neuroblastoma (ONB), sinonasal undifferentiated carcinoma (SNUC), and sinonasal neuroendocrine carcinoma (SNEC) are rare malignancies arising from the sinonasal tract with limited therapeuti...
www.mdpi.com
November 25, 2024 at 1:36 PM
Persistent unilateral #Sinonasal obstruction with a maxillary sinus mass and palatal erosion may indicate sinonasal ameloblastoma, a rare locally infiltrative odontogenic epithelial tumor. ja.ma/4AIvPTo
October 1, 2026 at 3:30 PM
i’ve been tied up in a paralyzing situation— needed a CT scan to check for pathologies, citing a tumour specifically, had to fight insurance to get it covered, kept rescheduling, trying to not overbook myself in case i needed an urgent sinonasal surgery, figuring out my options, etc.
February 8, 2026 at 4:23 AM
#Cannabis consumers are far less likely than non-users to develop chronic rhinitis & similar sinonasal diseases. Subjects who consumed cannabis less likely than non-users to suffer symptoms of sinonasal diseases, more frequent consumers possessing lowest risk. norml.org/news/2025/10...
Cannabis Use Inversely Associated With Rhinitis
Consumers less likely to suffer from chronic or allergic rhinitis
norml.org
October 19, 2025 at 11:46 AM
Obtained original path report for the sinonasal malignancy, which turned out to have been an intestinal-type sinonasal adenocarcinoma. Somehow ended up metastasising in a weird spot. Just goes to show how useful providing medical history can be.

#PathSky
March 21, 2025 at 5:57 AM
Boo! The October issue of Annals is here! Learn all about #sinonasal diseases like chronic #rhinosinusitis by reading the outstanding reviews this month - and don't miss the outstanding research articles and letters this month, as well. @annalsacaai.bsky.social #MedSky www.annallergy.org/current
September 30, 2026 at 1:14 PM
Chlorpheniramine is also a potent bitter taste receptor (T2R) agonist, and it may stimulate sinonasal innate immunity, triggering host defense mechanisms while blocking Ig-E-mediated mast cell activation and cytokine expression." /end
November 26, 2024 at 8:41 PM
Once again crying over someone else's kitty.

This time it's Lando of Temperamental Chucklefuck and Friends (on FB). Sweet floofy void was just diagnosed with sinonasal cancer.

Not sure anyone else here is familiar with the TCF crew, but what the hell.
June 13, 2024 at 11:28 AM
Dan wil je als onderzoeker serieus genomen worden, lijkt me, en dan noem je je vragenlijst omtrent bijholteproblematiek de... SNOT. Dus. 🤣
November 18, 2025 at 9:58 AM
A 12-month course of #dupilumab improves #otologic and #sinonasal #outcomes in adults with severe #nasal #polyps and #eosinophilic #otitis media, but experts differ on when to start a #biologic. www.medscape.com/vie...
October 3, 2026 at 10:30 PM
Distinct sinonasal microbiota define clinical subtypes of CRSwNP.
💡 Microbiome-based stratification may support personalized therapy for CRSwNP. onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
January 19, 2026 at 1:14 PM
😙💨 Contrary to investigators' expectations, cannabis consumers were less likely than non-users to develop chronic rhinitis and similar sinonasal diseases, with more frequent consumers possessing the lowest risk. #NORML #cannabis #marijuana #rhinitis #rhinosinusitis
Cannabis Use Inversely Associated With Rhinitis
Consumers less likely to suffer from chronic or allergic rhinitis
norml.org
October 27, 2025 at 6:03 PM
50s yom maxillary sinus
Dx: sinonasal papilloma, inverted-type
📸macro: partially translucent mass w/cerebriform opaque infoldings
📸low: downward growth of epi
📸 mucous cells (arrow) & microabscess formation
📸 thick squamous epi w/transmigrating neutrophils

#Pathsky #Otosky #ENTsky #macromicropath
January 16, 2026 at 6:10 PM
@biorxivpreprint.bsky.social Immune repertoire profiling reveals extensive clonal expansion of T and B cells in CXCL9-rich niches in sinonasal cancer
www.biorxiv.org/content/10.6...
June 9, 2026 at 4:16 PM
Glad to see this work led by Anna Zemke out: How do highly effective modulators (HEMT) influence the sinonasal microbiome of persons with cystic fibrosis? TLDR: Pseudomonas and Burkholderia decreased in samples containing these taxa at baseline.

onlinelibrary.wiley.com/doi/10.1002/...
Elexacaftor–tezacaftor–ivacaftor decreases pseudomonas abundance in the sinonasal microbiome in ...
Background Chronic rhinosinusitis (CRS) is common in individuals with cystic fibrosis (CF) and is marked by chronic inflammation and episodes of infection that negatively impact quality of life. Sev.....
onlinelibrary.wiley.com
October 16, 2023 at 1:25 AM
Just stumbled upon this interesting study on how #Nrf2 deletion amplifies air pollution-induced sinonasal #inflammation, highlighting the critical role of #antioxidant pathways in protecting against environmental exposures!

onlinelibrary.wiley.com/share/SYYKGM...

#immunology #upperairway 🧪
Deletion of Nrf2 Enhances Susceptibility to Sinonasal Inflammation After Short‐Term PM2.5 Exposure
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onlinelibrary.wiley.com
March 5, 2025 at 11:50 PM
Allergic rhinitis affects about 1 in 6 US adults.

💡 This JAMA Insights summarizes the impact of climate change and air pollution on sinonasal health and discusses evidence-based prevention and management strategies.

ja.ma/4rnralb
December 3, 2025 at 5:00 PM
Шо у людини на умі, то у пса на пемсюні

Джерело: ось це дослідження www.mdpi.com/2309-608X/8/...

Якщо маєте доступ до УФ світла, обовʼязково подивіться на свою шкіру, волосся і нігті. Якщо світиться зеленим чи оранжевим, ви гниючий мандарин, який прикидається людиною.
Malassezia: Zoonotic Implications, Parallels and Differences in Colonization and Disease in Humans and Animals
Malassezia spp. are commensals of the skin, oral/sinonasal cavity, lower respiratory and gastrointestinal tract. Eighteen species have been recovered from humans, other mammals and birds. They can als...
www.mdpi.com
May 31, 2024 at 11:26 AM
"Contrary to investigators’ expectations, subjects who consumed cannabis were less likely than non-users to suffer from symptoms of sinonasal diseases, with more frequent consumers possessing the lowest risk."
#MedicalMarijuana #MedicalCannabis #Marijuana #Cannabis #Rhinitis #Sinonasal
Cannabis Use Inversely Associated With Rhinitis
Consumers less likely to suffer from chronic or allergic rhinitis
norml.org
October 17, 2025 at 1:47 PM
When “vasculitis” isn’t vasculitis:
clinical images describe a case of nasal-type extranodal NK/T-cell lymphoma mimicking ANCA-associated vasculitis.

Initial biopsies were nondiagnostic, highlighting the importance of repeat tissue sampling when destructive sinonasal disease...
September 20, 2026 at 12:14 PM
New evidence-based guidelines refine HPV testing strategies for head & neck carcinomas, including updates on sinonasal SCC & p16 IHC interpretation. Stay informed on the latest recommendations.
#Oncology #MedSky
HPV Testing Guidelines Updated for Head and Neck Carcinomas
New evidence expands recommendations for sinonasal squamous cell carcinoma and standardizes p16 immunohistochemistry interpretation.
conexiant.com
April 3, 2025 at 1:36 PM
Expansile sinonasal mass, adult FM:

Dx: Epithelial-myoepithelial carcinoma. Biphasic salivary gland carcinoma composed of tightly coupled eosinophilic ductal cells and abluminal myoepithelial cells. Diffuse RAS Q61R IHC expression supportive while working thru the ddx.

PMID: 33481388

#PathSky
August 15, 2025 at 1:49 PM