#sinonasal
A 12-month course of #dupilumab improves #otologic and #sinonasal #outcomes in adults with severe #nasal #polyps and #eosinophilic #otitis media, but experts differ on when to start a #biologic. www.medscape.com/vie...
October 3, 2026 at 10:30 PM
Persistent unilateral #Sinonasal obstruction with a maxillary sinus mass and palatal erosion may indicate sinonasal ameloblastoma, a rare locally infiltrative odontogenic epithelial tumor. ja.ma/4AIvPTo
October 1, 2026 at 3:30 PM
An 82-year-old patient with a rare nasopharyngeal leiomyosarcoma experienced rapid local recurrence after surgery, ultimately leaving the tumor unresectable.

A new #CURiE case report examines the challenges of treating this aggressive head and neck malignancy.
Nasopharyngeal Leiomyosarcoma: Diagnostic Challenges and Management of a Rare Head and Neck Sarcoma
Leiomyosarcoma (LMS) is a rare, smooth-muscle malignancy and an uncommon sinonasal tumor, often diagnosed at a late stage due to non-specific symptoms and complex anatomy. We report an 82-year-old man...
cureus.com
September 30, 2026 at 1:19 PM
Boo! The October issue of Annals is here! Learn all about #sinonasal diseases like chronic #rhinosinusitis by reading the outstanding reviews this month - and don't miss the outstanding research articles and letters this month, as well. @annalsacaai.bsky.social #MedSky www.annallergy.org/current
September 30, 2026 at 1:14 PM
Congratulations to ARCP authors AProf Bryan Chan, @ProfClareScott, and Dr Cassie Turner on their publication exploring 42 years of data on sinonasal undifferentiated carcinoma (SNUC) in Queensland.

🔗 doi.org/10.1016/j.es...

#RareCancer #CancerResearch
September 24, 2026 at 12:13 AM
When “vasculitis” isn’t vasculitis:
clinical images describe a case of nasal-type extranodal NK/T-cell lymphoma mimicking ANCA-associated vasculitis.

Initial biopsies were nondiagnostic, highlighting the importance of repeat tissue sampling when destructive sinonasal disease...
September 20, 2026 at 12:14 PM
The Seldinger technique achieves sinonasal clotrimazole filling comparable to traditional trephination, while being less invasive. Cream volume scales with patient weight. Feasibility may be more limited in small-breed patients or those with normal sinonasal anatomy: jav.ma/trephination
September 15, 2026 at 4:53 PM
Simultaneous Dual Type 2 Biologic Therapy Improves Sinonasal Outcomes in Selected Patients With Chronic Rhinosinusitis With Nasal Polyps. Corresponding author: Friederike Bärhold

Read the article here: doi.org/10.1111/all.70452

#Allergy_journal
September 5, 2026 at 3:29 PM
Ophthopedia Update: Bilateral Multifocal Conjunctival Pyogenic Granulomas after Strabismus Surgery: A 73-year-old woman underwent uncomplicated bilateral strabismus surgery for diplopia secondary to a left sixth nerve palsy associated with amivantamab-treated… #Ophthalmology #ophthotwitter #eyecare
Bilateral Multifocal Conjunctival Pyogenic Granulomas after Strabismus Surgery
A 73-year-old woman underwent uncomplicated bilateral strabismus surgery for diplopia secondary to a left sixth nerve palsy associated with amivantamab-treated sinonasal carcinoma involving the clivus. Three weeks postoperatively, she developed bilateral multifocal pyogenic granulomas involving the bulbar and tarsal conjunctiva (A, B). Notably, she had previously experienced recurrent pyogenic granulomas at a right inframammary surgical site. The conjunctival lesions resolved completely within 2 months (C, D) with topical timolol 0.5% twice daily and a fluorometholone 0.1% taper, without surgical intervention.
dlvr.it
September 3, 2026 at 5:24 AM
Sinonasal teratocarcinosarcoma is too rare for normal drug development to bother with. Insilico Medicine's AI worked through thousands of biological pathways and found three promising molecular targets in months. massedcompute.com
September 2, 2026 at 10:03 AM
Hybrid Schwannoma of the Nasal Cavity: A Rare Case Report with Literature Review

Rafique et al. — ASIDE Case Reports
https://asidejournals.com/index.php/case-reports/article/view/103

#CaseReports #OpenAccess
Hybrid Schwannoma of the Nasal Cavity: A Rare Case Report with Literature Review
Sinonasal schwannomas are extremely rare, comprising only 4% of all head and neck schwannomas. Their atypical location and nonspecific symptoms often result in delayed diagnosis. This case highlights…
asidejournals.com
September 1, 2026 at 5:30 PM
imagine being told that you have a "switch/sucrose non-fermentable-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (integrase interactor 1)-deficient sinonasal carcinoma" type of cancer. short for SNCF. or five other things

i studied molecular biology in […]
Original post on social.treehouse.systems
social.treehouse.systems
August 31, 2026 at 6:10 AM
📃Scientific paper: Quantification of Budesonide Retained in the Sinonasal Cavity After High-Volume Saline Irrigation in Post-Operative Chronic Rhinosinusitis

Ref.: SAGE Publications, 2024

➡️ Continued on ES/IODE
August 30, 2026 at 5:02 PM
any sinonasal mass is auuuuugh, am having to deal with a recurrence of jna myself and fuck, can entirely sympathize. if there's any way to get them removed am hoping for the best for you D:
August 10, 2026 at 7:36 AM
New case shows how certain nasal cancers spread to brain lining
New case shows how certain nasal cancers spread to brain lining
Early detection and surgery are vital because sinonasal cancers can quickly spread to the brain lining.
vellito.com
July 31, 2026 at 10:20 PM
Subtraction Iodine Imaging Generated from Dual-Energy CT: Optimal Energy Determination and Evaluation of Sinonasal and Nasopharyngeal Malignancies
BACKGROUND AND PURPOSE: Subtraction iodine imaging (SII) and dual-energy CT-derived iodine imaging (DEII) have been proposed to enhance tumor delineation in head and neck cancers. However, the optimal energy for SII and the added diagnostic value of SII or DEII combined with conventional CT (CCT) remain uncertain. We aimed to determine the optimal energy for SII and to evaluate its incremental diagnostic benefits, as well as those of DEII. MATERIALS AND METHODS: Thirty-nine patients with histologically confirmed sinonasal or nasopharyngeal malignancies who underwent dual-energy CT (DECT) and contrast-enhanced MRI were included in this retrospective study. SII was generated by subtracting pre- and postcontrast virtual monochromatic images from the DECT images (45–75 keV, in 5-keV increments). Contrast-to-noise ratios (CNRs) were measured in the brain, prevertebral muscles, and skull base. Tumor delineation was assessed on a 5-point scale by 2 blinded radiologists, and the diagnostic performance for local tumor extension was evaluated using clustered receiver operating characteristic analysis with bootstrap resampling. RESULTS: The highest CNR across all anatomic sites was consistently achieved with SII at 65 keV. Tumor delineation scores were significantly higher with SII than with DEII (median, 4.5 versus 2.0; P < .001). Receiver operating characteristic analysis showed that CCT combined with SII yielded the highest diagnostic accuracy (area under the curve [AUC], 0.954), significantly outperforming CCT alone (AUC, 0.929; difference in AUC = 0.024; P = .02). The CCT combined with DEII did not show any significant improvements. CONCLUSIONS: SII at 65 keV provided optimal image quality, superior tumor delineation, and significantly improved diagnostic accuracy more than CCT did. Incorporating this imaging technique into CCT protocols may enhance the evaluation of tumor extension in sinonasal and nasopharyngeal malignancies. AUC : area under the curve CCT : conventional CT CNR : contrast-to-noise ratio DECT : dual-energy CT DEII : dual-energy CT–derived iodine imaging SII : subtraction iodine imaging
doi.org
July 28, 2026 at 3:00 PM
"Subtraction Iodine Imaging Generated from Dual-Energy CT: Optimal Energy Determination and Evaluation of Sinonasal and Nasopharyngeal Malignancies"

doi.org/10.3174/ajnr...
July 28, 2026 at 3:00 PM
#PubSaludMurcia Spontaneous Cerebrospinal Fluid Leak as the Initial Presentation of Sinonasal Glomangiopericytoma @Area6VegaMedia
Spontaneous Cerebrospinal Fluid Leak as the Initial Presentation of Sinonasal Glomangiopericytoma
This case report describes a 70-year-old woman with watery rhinorrhea, nocturnal cough, and progressive orthostatic headache, dysarthria, and somnolence.
doi.org
July 22, 2026 at 9:04 AM
Entenda como sangramento após mergulho levou mulher a descobrir câncer raro no nariz
O que parecia ser apenas um sangramento provocado por um mergulho durante as férias acabou marcando o início de uma longa batalha contra um câncer raro. A britânica Mel Frisby, de 35 anos, descobriu um carcinoma espinocelular sinonasal após notar que seu nariz começou a deformar semanas depois de uma viagem à Turquia, em 2022. Em vez de um cruzeiro, um bebê: casal dos EUA descobre gravidez ao entrar em trabalho de parto horas antes da viagem; caso viralizou Entenda: Menina de 18 meses tem as duas pernas amputadas por ter nascido sem um órgão Durante um passeio de barco, Mel decidiu vencer o medo do mar e saltou na água após ser incentivada por amigos. Ao voltar à superfície, sofreu um forte sangramento nasal. Como não sentia dor, acreditou que o impacto havia provocado apenas um ferimento e seguiu normalmente com a viagem. Dias depois, já de volta ao Reino Unido, percebeu uma pequena marca na ponta do nariz. Com o passar dos meses, porém, a região começou a inchar e mudar de formato. O alerta definitivo veio quando o marido insistiu para que ela procurasse atendimento médico ao notar a deformação. Inicialmente, os médicos descartaram uma fratura, mas exames revelaram uma infecção grave que comprometia o osso nasal. Mel foi diagnosticada com osteomielite, uma infecção óssea, e submetida a uma cirurgia de emergência para drenar a região e iniciar tratamento com antibióticos intravenosos. Apesar da intervenção, o quadro continuou piorando. O inchaço aumentou rapidamente e uma nova investigação levou à realização de biópsia e ressonância magnética. Três semanas depois, veio o diagnóstico definitivo: um carcinoma espinocelular sinonasal em estágio avançado, um tipo raro de câncer que acomete a cavidade nasal. Em retrospectiva, Mel percebeu que havia ignorado alguns sinais da doença. Ela acordava frequentemente com dores no nariz e apresentava cansaço intenso, sintomas que atribuiu ao estresse da rotina e às férias com os filhos. Segundo os médicos, se o tumor tivesse crescido em direção ao cérebro, poderia ter permanecido sem sintomas por muito mais tempo. O tratamento foi longo e agressivo. A britânica passou por quatro cirurgias reconstrutivas, seis procedimentos para controlar infecções e 30 sessões de radioterapia. Em uma das reconstruções, os médicos utilizaram cartilagem retirada de suas costelas para reconstruir parte do nariz após a remoção do osso comprometido pelo câncer. Além do impacto físico, Mel precisou lidar com as mudanças na aparência e com o desafio de explicar a doença aos três filhos. Antes da cirurgia, ela e o marido se despediram sabendo que aquela poderia ser a última vez que veriam seu rosto como era. Ao despertar, descobriu que os médicos haviam conseguido preservar a ponta e as narinas, permitindo uma reconstrução em vez do uso de uma prótese completa. Anos depois, ela decidiu compartilhar sua história nas redes sociais para alertar outras pessoas sobre os sintomas pouco conhecidos desse tipo de câncer. O relato viralizou, ultrapassou 16 milhões de visualizações no TikTok e colocou Mel em contato com outra sobrevivente que recebeu o mesmo diagnóstico aos 35 anos. A conversa a levou até um cirurgião especializado em reconstrução do osso nasal, reacendendo a esperança de concluir o processo de recuperação iniciado há quatro anos. Hoje, Mel afirma que seu objetivo é conscientizar sobre a importância do diagnóstico precoce e aproveitar cada momento ao lado da família. — Passei por um inferno para sobreviver, então estou me certificando de viver minha vida. A vida pode ser difícil para todos, mas é preciso encontrar uma maneira de seguir em frente — disse.
oglobo.globo.com
July 22, 2026 at 7:41 AM