💡Online now - the Spotlight "Drug ubiquitination: an unwelcome mode of action or a novel modality" from Richard de Heiden and Monique Mulder.

#NonCanonicalUbiquitination #Therapeutics #SmallMoleculeInhibitors

Read t it here: authors.elsevier.com/a/1m0Rm3S6Gf...

💊New article in @drugsincontext.bsky.social

Apremilast in osteoarthritis: exploring its therapeutic mechanisms

Rafiei et al.

www.drugsincontext.com/apremilast-i...

@medsky.social @me.pharmsky.app #osteoarthritis #smallmoleculeinhibitors #rheumatology

This review summarizes #m6A reader proteins in #LiverDisease, highlighting their roles in #RNAmetabolism, disease progression, & therapeutic potential, while emphasizing the promise of #SmallMoleculeInhibitors targeting reader–mRNA interactions.
#OpenAccess: doi.org/10.1016/j.ge...

This review summarizes the recent findings of #SREBPs mainly in terms of physiologic activation processes, regulatory processes, related diseases, and publicly available #SmallMoleculeInhibitors with #therapeuticpotential.

#OpenAccess: amm-journal.org/index.php/20...

#medsky #medicalresearch

Happy New Paper Day! We're excited to share this @natchembio.nature.com on #SmallMoleculeInhibitors of NorA, an efflux pump that is an important mediator of #antibioticresistance in #MRSA. It pumps antibiotics out , lowering their concentration in the cell.

doi.org/10.1038/s415...

#GileadSciences #LEOPharma #strategicpartnership #drugdevelopment #atopicdermatitis #asthma #COPD #dermatology #skindiseases #respiratory #smallmoleculeinhibitors #targetedproteindegraders #STAT6pathway #oralSTAT6products #topicalSTAT6products
pharmatimes.com/uncategorize...