#m6A
Single-base mapping of m6A in lncRNAs reveals a distinct landscape linked to transposable elements and RNA processing https://www.biorxiv.org/content/10.64898/2026.10.30.762970v1
November 1, 2026 at 1:35 AM
METTL3-mediated m6A modification of DNMT1 enhances ovarian cancer progression

Science advances · Kumari et al.
doi.org/10.1126/sciadv.aec2297
#RNAsky #RNAmods
METTL3-mediated m6A modification of DNMT1 enhances ovarian cancer progression
In this study, we identify a critical oncogenic role of the RNA methyltransferase METTL3 and the N6-methyladenosine (m6A) RNA modification pathway in HGSOC.
doi.org
November 5, 2026 at 1:14 AM
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November 5, 2026 at 8:30 PM
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Pokémon TCG – 30th Celebration Booster Box (JPN, M6a)
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November 5, 2026 at 8:15 PM
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November 4, 2026 at 12:02 AM
FTO does not function as an m6A eraser in AML: a reassessment using direct RNA nanopore sequencing

bioRxiv · Nicholson et al.
doi.org/10.1101/2025.10.22.681652
#RNAsky #RNAmods
FTO does not function as an m6A eraser in AML: a reassessment using direct RNA nanopore sequencing
We find that m6A stoichiometry, including at MYC-specific sites, remains unaffected by FTO knockdown or pharmacologic inhibition in AML.
doi.org
November 5, 2026 at 1:13 AM
Overcoming #ChemotherapyResistance remains a major challenge.
This study identifies #m6A-modified circLPAR3 as a driver of docetaxel resistance in #ProstateCancer, highlighting a potential target for restoring treatment response.
#GenesAndDiseases: doi.org/10.1016/j.ge...
November 3, 2026 at 2:01 PM
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Restock-Alarm · restockhero.eu
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November 4, 2026 at 12:30 PM
We have released slorado v0.7.0. Now supports both 5mC calling for DNA and m6A calling for RNA. Binaries are available for both AMD and NVIDIA GPUs
github.com/BonsonW/slor...
Release slorado-v0.7.0 · BonsonW/slorado
What's Changed new experimental --async yes|no option that runs I/O, CPU and GPU work at the same time (the reads will be unordered in the output) experimental support for rna004_sup@v6.0.0 baseca...
github.com
November 5, 2026 at 6:43 AM
Single-base mapping of m6A in lncRNAs reveals a distinct landscape linked to transposable elements and RNA processing https://www.biorxiv.org/content/10.64898/2026.10.30.762970v1
November 1, 2026 at 1:35 AM
WTAP-mediated m6A methylation stabilizes pIgR mRNA and attenuates smoke-induced epithelial inflammation and apoptosis

iScience · Li et al.
doi.org/10.1016/j.isci.2026.117958
#RNAsky #RNAmods
WTAP-mediated m6A methylation stabilizes pIgR mRNA and attenuates smoke-induced epithelial inflammation and apoptosis
We show that smoke exposure downregulates the m6A writer-complex component WTAP and reduces global m6A methylation.
doi.org
November 2, 2026 at 12:05 AM
m6A-modified hsa_circ_0010996 regulates ferroptosis in anti-tuberculosis drug-induced liver injury cells by binding to EIF4A3

Toxicology and applied pharmacology · Wang et al.
doi.org/10.1016/j.taap.2026.118100
#RNAsky #RNAmods
m6A-modified hsa_circ_0010996 regulates ferroptosis in anti-tuberculosis drug-induced liver injury cells by binding to EIF4A3
Toxicology and applied pharmacology · Wang Q, Long M, Song T, Yao J, Liu Y, Meng C, Feng F.
doi.org
November 4, 2026 at 8:24 PM
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November 1, 2026 at 11:45 AM
ZC3H13 promotes cervical cancer cell proliferation and stemness and reduces cisplatin sensitivity and apoptosis by stabilizing CTHRC1 mRNA in an m6A-Dependent manner

Gene · Aihemaitijiang et al.
doi.org/10.1016/j.gene.2026.150474
#RNAsky #RNAmods
ZC3H13 promotes cervical cancer cell proliferation and stemness and reduces cisplatin sensitivity and apoptosis by stabilizing CTHRC1 mRNA in an m6A-Dependent manner
Gene · Aihemaitijiang F, Meng X, Yumai A, Muhanmude Y.
doi.org
November 3, 2026 at 8:02 PM
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October 31, 2026 at 9:45 PM
Some other dribs and drabs:

-m6A methylation is involved in NLRP3 activation

-L arginine acts as a brake on NLRP3

-'omics paper - DNA methylation distinguishes gout and hyperuricemia pubmed.ncbi.nlm.nih.gov/42810907/

#2026GCAN #ACR26
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pubmed.ncbi.nlm.nih.gov
November 4, 2026 at 2:34 PM
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November 2, 2026 at 8:17 AM
Huashi Runzao Decoction alleviates ferroptosis in salivary gland epithelial cells through RBM15B-associated m6A regulation in Sjögren's disease

Journal of ethnopharmacology · Deng et al.
doi.org/10.1016/j.jep.2026.122583
#RNAsky #RNAmods
Huashi Runzao Decoction alleviates ferroptosis in salivary gland epithelial cells through RBM15B-associated m6A regulation in Sjögren's disease
Journal of ethnopharmacology · Deng T, Zhang H, Wang Y, Jiao Y, Wang Z, Shi T, Xu J, Wen C, Zhang J, Zhang K, Su S, Deng T, Tao Q, Xiao C, Luo J.
doi.org
November 3, 2026 at 8:02 PM
M6A-modified Gata1 promotes endoplasmic reticulum stress during acute kidney injury via suppressing Sesn2 : Gata1 promotes acute kidney injury by downregulating Sesn2

Molecular and cellular biochemistry · Yan et al.
doi.org/10.1007/s11010-026-05785-7
#RNAsky #RNAmods
M6A-modified Gata1 promotes endoplasmic reticulum stress during acute kidney injury via suppressing Sesn2 : Gata1 promotes acute kidney injury by downregulating Sesn2
Molecular and cellular biochemistry · Yan WZ, Wang JY, Chen YY, Zhang M, Liu GY, He LY.
doi.org
November 2, 2026 at 10:16 PM
METTL7B-Mediated m6A Modification of PLEKHA4 Suppresses Ferroptosis via Reducing AURKA Ubiquitination to Promote Papillary Thyroid Cancer Progression

Cancer medicine · Lin et al.
doi.org/10.1002/cam4.72373
#RNAsky #RNAmods
METTL7B-Mediated m6A Modification of PLEKHA4 Suppresses Ferroptosis via Reducing AURKA Ubiquitination to Promote Papillary Thyroid Cancer Progression
Cancer medicine · Lin W, Wu K, Chen J, Yu Z, Zhang H, Chen X.
doi.org
November 1, 2026 at 6:21 PM
FTO Dependent Trim14 m6A Modification Regulates Neuroinflammation in MPTP-Induced Parkinson's Disease Models via the RhoA/ROCK Pathway

Molecular neurobiology · Liu et al.
doi.org/10.1007/s12035-026-06299-5
#RNAsky #RNAmods
FTO Dependent Trim14 m6A Modification Regulates Neuroinflammation in MPTP-Induced Parkinson's Disease Models via the RhoA/ROCK Pathway
Here, we explored whether m6A modification is associated with microglia-mediated inflammation using MPTP-treated mice and MPP+-exposed BV2 cells.
doi.org
October 31, 2026 at 5:38 PM
Melatonin Suppresses Colorectal Cancer Alongside Coordinated Changes in H3K4me3Q5ser and m6A Modifications

Journal of pineal research · Zhang et al.
doi.org/10.1111/jpi.70192
#RNAsky #RNAmods
Melatonin Suppresses Colorectal Cancer Alongside Coordinated Changes in H3K4me3Q5ser and m6A Modifications
Journal of pineal research · Zhang W, Yuan L, Yu D, Qi S, Liu C, Wang D, Wang W, Zhang Y, Zhang S, Lu L, Wu M, Huang Y.
doi.org
November 1, 2026 at 6:21 PM