Marcel Dickmanns | 🌿❄️🔬
@madic.bsky.social
Shooting electrons, ions and photons (mainly) at plants to study cell-cell communication @mpibiochem.bsky.social & @hhu.de
Pinned
It's out! 🥳
In situ architecture of #plasmodesmata - plant cytoplasmic bridges - by #cryoET.
📝 Paper: www.nature.com/articles/s41...
🧵 Thread: bsky.app/profile/madi...
#teamtomo #proteomics #AlphaFold
In situ architecture of #plasmodesmata - plant cytoplasmic bridges - by #cryoET.
📝 Paper: www.nature.com/articles/s41...
🧵 Thread: bsky.app/profile/madi...
#teamtomo #proteomics #AlphaFold
Reposted by Marcel Dickmanns | 🌿❄️🔬
The first preprint of my lab has just come out doi.org/10.64898/202...
This paper came out at the same day on the sudden passing of Prof. Meng Chen. Without his work, this paper would not have existed. He was an extremely supportive member of the plant photobiology community..
This paper came out at the same day on the sudden passing of Prof. Meng Chen. Without his work, this paper would not have existed. He was an extremely supportive member of the plant photobiology community..
doi.org
September 13, 2026 at 2:48 PM
The first preprint of my lab has just come out doi.org/10.64898/202...
This paper came out at the same day on the sudden passing of Prof. Meng Chen. Without his work, this paper would not have existed. He was an extremely supportive member of the plant photobiology community..
This paper came out at the same day on the sudden passing of Prof. Meng Chen. Without his work, this paper would not have existed. He was an extremely supportive member of the plant photobiology community..
Reposted by Marcel Dickmanns | 🌿❄️🔬
Nice work by @cellsensing.bsky.social Glycan recognition by a plant damage-sensing immune receptor www.science.org/doi/10.1126/...
Glycan recognition by a plant damage-sensing immune receptor
Pathogens target and degrade the extracellular matrix surrounding plant cells. A central question is how cell wall-derived damage-associated molecular patterns (DAMPs) are recognized and integrated to...
www.science.org
September 11, 2026 at 7:00 AM
Nice work by @cellsensing.bsky.social Glycan recognition by a plant damage-sensing immune receptor www.science.org/doi/10.1126/...
Reposted by Marcel Dickmanns | 🌿❄️🔬
I am looking for a lab manager for my group that I will be starting at the @fmiscience.bsky.social in February! We will use in situ structural biology to investigate dynamic ciliary processes. More info here —> bsky.app/profile/comp... #cilia #teamtomo #proteomics #protistsky
📢 We’re hiring!
Join Caitlyn McCafferty’s (@computingcaitie.bsky.social) new group as Lab Manager and help shape lab operations, develop protocols and support research on the structure and dynamics of motile cilia. Apply by October 9: www.fmi.ch/education-ca...
Join Caitlyn McCafferty’s (@computingcaitie.bsky.social) new group as Lab Manager and help shape lab operations, develop protocols and support research on the structure and dynamics of motile cilia. Apply by October 9: www.fmi.ch/education-ca...
September 9, 2026 at 9:33 AM
I am looking for a lab manager for my group that I will be starting at the @fmiscience.bsky.social in February! We will use in situ structural biology to investigate dynamic ciliary processes. More info here —> bsky.app/profile/comp... #cilia #teamtomo #proteomics #protistsky
Reposted by Marcel Dickmanns | 🌿❄️🔬
Preprint🚨: Exopolysaccharide export complex PelBC of Pseudomonas aeruginosa attenuates the dynamics of the surrounding outer membrane.
Longer in preparation than in actual making. Blame summer time and perfectionism 🫠 A brief tour, to keep the feed alive over the wknd
www.biorxiv.org/content/10.6...
Longer in preparation than in actual making. Blame summer time and perfectionism 🫠 A brief tour, to keep the feed alive over the wknd
www.biorxiv.org/content/10.6...
August 23, 2026 at 12:52 PM
Preprint🚨: Exopolysaccharide export complex PelBC of Pseudomonas aeruginosa attenuates the dynamics of the surrounding outer membrane.
Longer in preparation than in actual making. Blame summer time and perfectionism 🫠 A brief tour, to keep the feed alive over the wknd
www.biorxiv.org/content/10.6...
Longer in preparation than in actual making. Blame summer time and perfectionism 🫠 A brief tour, to keep the feed alive over the wknd
www.biorxiv.org/content/10.6...
Reposted by Marcel Dickmanns | 🌿❄️🔬
PLEASE SHARE! New job openings in my lab @zmbp-tuebingen.bsky.social. We have a broad interest into the mechanistic basis of how molecular complexes are rewired during cellular development in plants and during invasion by pathogens.
🌱🍄🔬
See details below 👇
#PlantSciJobs
🌱🍄🔬
See details below 👇
#PlantSciJobs
August 5, 2026 at 8:15 AM
PLEASE SHARE! New job openings in my lab @zmbp-tuebingen.bsky.social. We have a broad interest into the mechanistic basis of how molecular complexes are rewired during cellular development in plants and during invasion by pathogens.
🌱🍄🔬
See details below 👇
#PlantSciJobs
🌱🍄🔬
See details below 👇
#PlantSciJobs
Reposted by Marcel Dickmanns | 🌿❄️🔬
We've been seeing a lot of "in situ" lately in titles from fancy journals (not pointing any fingers 👀). I’ve delayed posting this, but as more and more come out, I'm afraid "in situ" is becoming an empty buzzword, much like "near-atomic" was for SPA 🔬 1/n
#cryo-ET #cryo-EM #cryoET #cryoEM 🧪
#cryo-ET #cryo-EM #cryoET #cryoEM 🧪
August 7, 2026 at 2:27 PM
Reposted by Marcel Dickmanns | 🌿❄️🔬
“move from preprint to peer-reviewed publication leaves the central claims of most abstracts intact, indicating preprints are a reliable source…papers that were never posted as preprints were retracted at roughly twice the rate of those that were…” www.biorxiv.org/content/10.6...
Tracking claim changes from preprint to publication across 72,644 biomedical studies using large language models
Preprints now disseminate a large share of biomedical research before peer review. Because they have not yet passed peer review, some scientists regard preprint claims as unverified or potentially unr...
www.biorxiv.org
July 6, 2026 at 12:51 PM
“move from preprint to peer-reviewed publication leaves the central claims of most abstracts intact, indicating preprints are a reliable source…papers that were never posted as preprints were retracted at roughly twice the rate of those that were…” www.biorxiv.org/content/10.6...
Reposted by Marcel Dickmanns | 🌿❄️🔬
#pictureofthemonth: Plant cells use tiny pores called plasmodesmata to talk to each other. The rendering, shows how everything links together.
More: www.biochem.mpg.de/baumeister-p...
July – Calendar of @mpiforbi.bsky.social and @mpibiochem.bsky.social
📸 by Monika Krause & Marcel Dickmanns
More: www.biochem.mpg.de/baumeister-p...
July – Calendar of @mpiforbi.bsky.social and @mpibiochem.bsky.social
📸 by Monika Krause & Marcel Dickmanns
July 3, 2026 at 2:29 PM
#pictureofthemonth: Plant cells use tiny pores called plasmodesmata to talk to each other. The rendering, shows how everything links together.
More: www.biochem.mpg.de/baumeister-p...
July – Calendar of @mpiforbi.bsky.social and @mpibiochem.bsky.social
📸 by Monika Krause & Marcel Dickmanns
More: www.biochem.mpg.de/baumeister-p...
July – Calendar of @mpiforbi.bsky.social and @mpibiochem.bsky.social
📸 by Monika Krause & Marcel Dickmanns
Reposted by Marcel Dickmanns | 🌿❄️🔬
1/8
What if the genomic features we associate with fungal pathogens were also used by mutualists?
We assembled 41 scale lichen genomes across 11 Peltigera species with 30 chromosome scale and 5 T2T revealing an unexpected genomic toolkit behind lichen symbiosis. doi.org/10.64898/202...
#lichen
What if the genomic features we associate with fungal pathogens were also used by mutualists?
We assembled 41 scale lichen genomes across 11 Peltigera species with 30 chromosome scale and 5 T2T revealing an unexpected genomic toolkit behind lichen symbiosis. doi.org/10.64898/202...
#lichen
A chromosome-scale super-pangenome of the lichen genus Peltigera reveals genome architecture and expanded interaction repertoires shared across pathogenic and mutualistic fungi
Fungi engage in associations with other organisms across a continuum from pathogenic to mutualistic lifestyles. Hence, they require a compendium of molecular capacities, including partner recognition,...
doi.org
June 25, 2026 at 7:11 AM
1/8
What if the genomic features we associate with fungal pathogens were also used by mutualists?
We assembled 41 scale lichen genomes across 11 Peltigera species with 30 chromosome scale and 5 T2T revealing an unexpected genomic toolkit behind lichen symbiosis. doi.org/10.64898/202...
#lichen
What if the genomic features we associate with fungal pathogens were also used by mutualists?
We assembled 41 scale lichen genomes across 11 Peltigera species with 30 chromosome scale and 5 T2T revealing an unexpected genomic toolkit behind lichen symbiosis. doi.org/10.64898/202...
#lichen
Reposted by Marcel Dickmanns | 🌿❄️🔬
Happy to finally share that I will be starting my independent group at the @fmiscience.bsky.social in Feb 2027 in a vibrant new environment. We will use integrative in situ structural cell biology methods to investigate ciliary structure and dynamics in several model (and non-model 👀) systems!!
June 22, 2026 at 2:37 PM
Happy to finally share that I will be starting my independent group at the @fmiscience.bsky.social in Feb 2027 in a vibrant new environment. We will use integrative in situ structural cell biology methods to investigate ciliary structure and dynamics in several model (and non-model 👀) systems!!
Reposted by Marcel Dickmanns | 🌿❄️🔬
Better vitrification = better cryo-ET.
We've opened an RFA for two-year grants to advance vitrification techniques for biological samples—welcoming applications from researchers in heat transfer, cryogenics, and materials science.
Apply here: bit.ly/4uip6eJ
We've opened an RFA for two-year grants to advance vitrification techniques for biological samples—welcoming applications from researchers in heat transfer, cryogenics, and materials science.
Apply here: bit.ly/4uip6eJ
June 4, 2026 at 6:24 PM
Better vitrification = better cryo-ET.
We've opened an RFA for two-year grants to advance vitrification techniques for biological samples—welcoming applications from researchers in heat transfer, cryogenics, and materials science.
Apply here: bit.ly/4uip6eJ
We've opened an RFA for two-year grants to advance vitrification techniques for biological samples—welcoming applications from researchers in heat transfer, cryogenics, and materials science.
Apply here: bit.ly/4uip6eJ
Reposted by Marcel Dickmanns | 🌿❄️🔬
Check out our latest work! AlphaFold 3 revealed a transient immune receptor complex that eluded biochemical studies for almost a decade 🤯 We describe a conserved structural logic underlying sensor–helper communication in an NLR immune receptor network 🧵👇
May 20, 2026 at 11:42 AM
Check out our latest work! AlphaFold 3 revealed a transient immune receptor complex that eluded biochemical studies for almost a decade 🤯 We describe a conserved structural logic underlying sensor–helper communication in an NLR immune receptor network 🧵👇
Reposted by Marcel Dickmanns | 🌿❄️🔬
Thrilled to share the updated video of my paper in Nature with Maciej (under supervision of @simonemattei.bsky.social & @jomaalab.bsky.social) Proud to use Cryo-ET to uncover how hibernation factors are key to translation restart! To model PTMs in situ and render animations fulfilled my PhD dream!🥹🎉
May 14, 2026 at 8:12 AM
Thrilled to share the updated video of my paper in Nature with Maciej (under supervision of @simonemattei.bsky.social & @jomaalab.bsky.social) Proud to use Cryo-ET to uncover how hibernation factors are key to translation restart! To model PTMs in situ and render animations fulfilled my PhD dream!🥹🎉
Reposted by Marcel Dickmanns | 🌿❄️🔬
We have an open-rank professorship position open @unileiden.bsky.social Institute of Biology: careers.universiteitleiden.nl/job/Assistan... welcome to apply!
due: 7 June
due: 7 June
Assistant/Associate/Full Professor Plant Molecular (and Cell) Biology
Assistant/Associate/Full Professor Plant Molecular (and Cell) Biology
careers.universiteitleiden.nl
May 19, 2026 at 9:58 AM
We have an open-rank professorship position open @unileiden.bsky.social Institute of Biology: careers.universiteitleiden.nl/job/Assistan... welcome to apply!
due: 7 June
due: 7 June
Reposted by Marcel Dickmanns | 🌿❄️🔬
New OA Article: "In situ architecture of plasmodesmata in Physcomitrium resolved by cryo-electron tomography" rdcu.be/fjjiK
Plasmodesmata are gated by cell wall remodelling; helical protein assemblies scaffold internal membranes; implications for molecular filtering.
Plasmodesmata are gated by cell wall remodelling; helical protein assemblies scaffold internal membranes; implications for molecular filtering.
May 18, 2026 at 10:20 AM
New OA Article: "In situ architecture of plasmodesmata in Physcomitrium resolved by cryo-electron tomography" rdcu.be/fjjiK
Plasmodesmata are gated by cell wall remodelling; helical protein assemblies scaffold internal membranes; implications for molecular filtering.
Plasmodesmata are gated by cell wall remodelling; helical protein assemblies scaffold internal membranes; implications for molecular filtering.
Reposted by Marcel Dickmanns | 🌿❄️🔬
It's finally out!
Molecular architecture of mammalian AP3:ARF1 carriers - a mechanism for lysosomal membrane protein trafficking - from a combination of #biochemistry, #cryoET and #cellbiology
📝 Paper: www.science.org/doi/10.1126/...
🧵 Thread: subsequently
#teamtomo #membranetrafficking
Molecular architecture of mammalian AP3:ARF1 carriers - a mechanism for lysosomal membrane protein trafficking - from a combination of #biochemistry, #cryoET and #cellbiology
📝 Paper: www.science.org/doi/10.1126/...
🧵 Thread: subsequently
#teamtomo #membranetrafficking
The architecture of carriers formed by AP3:ARF1 for lysosomal membrane protein transport: www.science.org/doi/10.1126/.... Work from @jggkaufman.bsky.social, in collaboration with @dgershlick.bsky.social and David Owen. @mpibiochem.bsky.social @thecimr.bsky.social
Architecture of clathrin-independent AP3:ARF1-coated carriers
AP3 generates clathrin-free carriers on endosomes by organizing via ARF1 dimers into elongated membrane-deforming arrays.
www.science.org
May 18, 2026 at 8:34 PM
It's finally out!
Molecular architecture of mammalian AP3:ARF1 carriers - a mechanism for lysosomal membrane protein trafficking - from a combination of #biochemistry, #cryoET and #cellbiology
📝 Paper: www.science.org/doi/10.1126/...
🧵 Thread: subsequently
#teamtomo #membranetrafficking
Molecular architecture of mammalian AP3:ARF1 carriers - a mechanism for lysosomal membrane protein trafficking - from a combination of #biochemistry, #cryoET and #cellbiology
📝 Paper: www.science.org/doi/10.1126/...
🧵 Thread: subsequently
#teamtomo #membranetrafficking
It's out! 🥳
In situ architecture of #plasmodesmata - plant cytoplasmic bridges - by #cryoET.
📝 Paper: www.nature.com/articles/s41...
🧵 Thread: bsky.app/profile/madi...
#teamtomo #proteomics #AlphaFold
In situ architecture of #plasmodesmata - plant cytoplasmic bridges - by #cryoET.
📝 Paper: www.nature.com/articles/s41...
🧵 Thread: bsky.app/profile/madi...
#teamtomo #proteomics #AlphaFold
May 14, 2026 at 11:07 AM
It's out! 🥳
In situ architecture of #plasmodesmata - plant cytoplasmic bridges - by #cryoET.
📝 Paper: www.nature.com/articles/s41...
🧵 Thread: bsky.app/profile/madi...
#teamtomo #proteomics #AlphaFold
In situ architecture of #plasmodesmata - plant cytoplasmic bridges - by #cryoET.
📝 Paper: www.nature.com/articles/s41...
🧵 Thread: bsky.app/profile/madi...
#teamtomo #proteomics #AlphaFold
Reposted by Marcel Dickmanns | 🌿❄️🔬
We're super excited to share MissAlignment: a new ML-based approach to reference-free tilt series alignment, spearheaded by @martenchaillet.bsky.social. We think it's going to make your cryo-ET life a lot better.
Preprint: www.biorxiv.org/content/10.6...
Code: github.com/warpem/miss-...
🧶 Thread:
Preprint: www.biorxiv.org/content/10.6...
Code: github.com/warpem/miss-...
🧶 Thread:
May 3, 2026 at 6:11 AM
We're super excited to share MissAlignment: a new ML-based approach to reference-free tilt series alignment, spearheaded by @martenchaillet.bsky.social. We think it's going to make your cryo-ET life a lot better.
Preprint: www.biorxiv.org/content/10.6...
Code: github.com/warpem/miss-...
🧶 Thread:
Preprint: www.biorxiv.org/content/10.6...
Code: github.com/warpem/miss-...
🧶 Thread:
Reposted by Marcel Dickmanns | 🌿❄️🔬
New preprint 🚀 ❄️
We developed Autogrid-compatible HPF planchettes that enable direct freezing of clipped EM grids and streamline integration with cryo-FIB workflows
✔️ improved grid stability
✔️ reduced handling
✔️ robust vitrification (🦠 🧫 🧠)
A step toward routine HPF for complex samples
#teamtomo
We developed Autogrid-compatible HPF planchettes that enable direct freezing of clipped EM grids and streamline integration with cryo-FIB workflows
✔️ improved grid stability
✔️ reduced handling
✔️ robust vitrification (🦠 🧫 🧠)
A step toward routine HPF for complex samples
#teamtomo
April 22, 2026 at 6:18 AM
New preprint 🚀 ❄️
We developed Autogrid-compatible HPF planchettes that enable direct freezing of clipped EM grids and streamline integration with cryo-FIB workflows
✔️ improved grid stability
✔️ reduced handling
✔️ robust vitrification (🦠 🧫 🧠)
A step toward routine HPF for complex samples
#teamtomo
We developed Autogrid-compatible HPF planchettes that enable direct freezing of clipped EM grids and streamline integration with cryo-FIB workflows
✔️ improved grid stability
✔️ reduced handling
✔️ robust vitrification (🦠 🧫 🧠)
A step toward routine HPF for complex samples
#teamtomo
Reposted by Marcel Dickmanns | 🌿❄️🔬
Check out our new release on BioRxiv
co-lead by @pm-mueller.bsky.social
👉 rb.gy/lnrizk
special🙏 to
Severine Kunz #MDC
@leventallab.bsky.social
@andimicroscopy.bsky.social
@ewerslab.bsky.social and Kedar Narayan @NCI CCR VolumeEM
Are the days of discovering new cellular structures over?? /1
co-lead by @pm-mueller.bsky.social
👉 rb.gy/lnrizk
special🙏 to
Severine Kunz #MDC
@leventallab.bsky.social
@andimicroscopy.bsky.social
@ewerslab.bsky.social and Kedar Narayan @NCI CCR VolumeEM
Are the days of discovering new cellular structures over?? /1
April 15, 2026 at 4:52 PM
Check out our new release on BioRxiv
co-lead by @pm-mueller.bsky.social
👉 rb.gy/lnrizk
special🙏 to
Severine Kunz #MDC
@leventallab.bsky.social
@andimicroscopy.bsky.social
@ewerslab.bsky.social and Kedar Narayan @NCI CCR VolumeEM
Are the days of discovering new cellular structures over?? /1
co-lead by @pm-mueller.bsky.social
👉 rb.gy/lnrizk
special🙏 to
Severine Kunz #MDC
@leventallab.bsky.social
@andimicroscopy.bsky.social
@ewerslab.bsky.social and Kedar Narayan @NCI CCR VolumeEM
Are the days of discovering new cellular structures over?? /1
Reposted by Marcel Dickmanns | 🌿❄️🔬
I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...
April 8, 2026 at 6:25 AM
I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...
Reposted by Marcel Dickmanns | 🌿❄️🔬
A new webinar series is born - ''MechanoBioTalks - Mechanics, Materials and Living Matter", to bring together and inspire researchers interested in biomechanics, biophysics and biology across different kingdoms of life. Join us!
For info and registration visit green-te.nl/activities/
For info and registration visit green-te.nl/activities/
Activities - GreenTE
Activities Webinars ”MechanoBioTalks – Mechanics, Materials and Living Matter” is a webinar series supported by the GreenTE consortium and organized […]
green-te.nl
January 22, 2026 at 8:18 AM
A new webinar series is born - ''MechanoBioTalks - Mechanics, Materials and Living Matter", to bring together and inspire researchers interested in biomechanics, biophysics and biology across different kingdoms of life. Join us!
For info and registration visit green-te.nl/activities/
For info and registration visit green-te.nl/activities/
Reposted by Marcel Dickmanns | 🌿❄️🔬
Our work on #hornwort #pyrenoids is finally out in @science.org! 🎉 We uncovered how hornworts pack their Rubisco into pyrenoids and successfully recreated them in Arabidopsis. A key step toward engineering more efficient photosynthesis in crops @btiscience.bsky.social www.science.org/doi/10.1126/...
An unconventional Rubisco small subunit underpins the CO2-concentrating organelle in land plants
In many algae, photosynthesis is boosted by biophysical CO2-concentrating mechanisms, which pack the CO2-fixing enzyme Rubisco into liquid-like organelles called pyrenoids. Engineering C3 crops with a...
www.science.org
March 5, 2026 at 8:03 PM
Our work on #hornwort #pyrenoids is finally out in @science.org! 🎉 We uncovered how hornworts pack their Rubisco into pyrenoids and successfully recreated them in Arabidopsis. A key step toward engineering more efficient photosynthesis in crops @btiscience.bsky.social www.science.org/doi/10.1126/...
Reposted by Marcel Dickmanns | 🌿❄️🔬
Excited to announce I’m starting a new lab at @gmivienna.bsky.social (Vienna BioCentre) in Sept 2026
We study how carbon fixation is inherited and maintained in algae using cryo-ET, imaging, environmental sampling&more
Looking for people who want to build the lab together, get in touch!
#teamtomo
We study how carbon fixation is inherited and maintained in algae using cryo-ET, imaging, environmental sampling&more
Looking for people who want to build the lab together, get in touch!
#teamtomo
March 11, 2026 at 12:30 PM
Excited to announce I’m starting a new lab at @gmivienna.bsky.social (Vienna BioCentre) in Sept 2026
We study how carbon fixation is inherited and maintained in algae using cryo-ET, imaging, environmental sampling&more
Looking for people who want to build the lab together, get in touch!
#teamtomo
We study how carbon fixation is inherited and maintained in algae using cryo-ET, imaging, environmental sampling&more
Looking for people who want to build the lab together, get in touch!
#teamtomo
Reposted by Marcel Dickmanns | 🌿❄️🔬
We are currently recruiting PhD students, postdocs, and a group leader to join the Institute.
If you’re interested, please send me a personal message or email your CV and a brief motivation letter to: [email protected].
If you’re interested, please send me a personal message or email your CV and a brief motivation letter to: [email protected].
March 6, 2026 at 7:24 AM
We are currently recruiting PhD students, postdocs, and a group leader to join the Institute.
If you’re interested, please send me a personal message or email your CV and a brief motivation letter to: [email protected].
If you’re interested, please send me a personal message or email your CV and a brief motivation letter to: [email protected].