#CalciumSignaling
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gmj-georgia.bsky.social
Muscle contraction isn't a single event—it's a five-stage molecular cascade involving electricity, calcium, proteins, and energy. Unde…

#Calciumsignaling #Musclecontraction #Musclephysiology #Myosinactin #Neuromuscularjunction

#Calciumsignaling #Musclecontraction #Musclephysiology #Myosinactin …
How Do Muscles Contract? The Science Explained
Muscle contraction isn't a single event—it's a five-stage molecular cascade involving electricity, calcium, proteins, and energy. Unde… #Calciumsignaling #Musclecontraction #Musclephysiology #Myosinactin #Neuromuscularjunction
news.gmj.ge
November 9, 2026 at 1:26 AM
pjsaez.bsky.social
#CellCommunication + #CalciumSignaling
What else can you ask for?
hhmi-science.bsky.social HHMI @hhmi-science.bsky.social · Sep 19
Lighting up your screen: a larval zebrafish's cellular activity. Developed by researchers at our Janelia Research Campus, WHaloCaMP is a biosensor that detects calcium signals — a key part of cellular communication — & offers a window into how cells & organs work together. 🎥 Helen Farrants, HHMI JRC
September 20, 2026 at 6:39 AM
beckerdirk.bsky.social
#PlantSciences #CalciumSignaling High humidity induces CNGC2- and CNGC4-mediated increases in cytosolic Ca2+ concentrations www.pnas.org/doi/10.1073/...
www.pnas.org
December 14, 2024 at 8:11 AM
drdickhilleary.bsky.social
New preprint from the He lab: FERONIA is required for high humidity-induced Ca²⁺ waves and adaptive leaf hyponasty in Arabidopsis. Whole-plant calcium imaging across three species. www.biorxiv.org/content/10.6... #plantbiology #calciumsignaling
April 29, 2026 at 12:30 PM
stressbiology.bsky.social
Tackling abiotic stress in plants: recent insights and trends
Heng Zhang, Zhaobo Lang, Jian-Kang Zhu & Pengcheng Wang

link.springer.com/article/10.1...

#AbioticStress #CalciumSignaling #LLPS
Tackling abiotic stress in plants: recent insights and trends - Stress Biology
Plants, as sessile organisms, must adapt to a range of abiotic stresses, including drought, salinity, heat, and cold, which are increasingly exacerbated by climate change. These stresses significantly...
link.springer.com
February 17, 2025 at 5:31 PM
scienceopen.bsky.social
🔓📄 'Activation of Piezo 1 in the Pathogenesis of Glaucoma' - an article published in 'Neuropharmacology and Therapy' on #ScienceOpen:

🖇️ #GlaucomaResearch #Piezo1 #CalciumSignaling #Cofilin
Activation of Piezo 1 in the Pathogenesis of Glaucoma
Glaucoma is an eye disorder that damages the retinal ganglion cells and the optic nerve, and can cause vision loss or blindness. However, a lack of understanding of the underlying pathogenetic mechanisms has hampered the development of effective therapies.
www.scienceopen.com
August 29, 2025 at 7:31 AM
benderlab.bsky.social
Excited to share our latest publication now available online:
rdcu.be/eJNGB

“Optogenetic induction of subcellular Ca²⁺ events in megakaryocytes and platelets using a highly Ca²⁺-conductive channelrhodopsin.”

#Platelets #Megakaryocytes #Research #Optogenetics #CalciumSignaling
Optogenetic induction of subcellular Ca2+ events in megakaryocytes and platelets using a highly Ca2+-conductive channelrhodopsin
Communications Biology - The authors present a novel channel rhodopsin variant with enhanced Ca2+ conductance in megakaryocytes and platelets.
rdcu.be
October 7, 2025 at 11:32 AM
kwitschas.bsky.social
Happy to share my new review "From IP3RPEP6 inhibition of IP3 receptor
channels to insights: do channel subunits collaborate or cooperate?"
rdcu.be/ew0kv #calciumsignaling #ionchannels
#science
From IP3RPEP6 Inhibition of IP3 receptor channels to insights: do channel subunits collaborate or cooperate?
rdcu.be
July 21, 2025 at 7:40 PM
labcosta.bsky.social
Hello dear...I am also here...let's start with this:

Check out this timelapse of growing Arabidopsis leaves expressing a Calcium sensor. Nature's signal in motion! 🌱 #PlantScience #CalciumSignaling #Arabidopsis"
November 25, 2024 at 6:25 AM
josephwgordon.bsky.social
www.linkedin.com/posts/saeid-...
#musclebiology #autophagy #mitophagy #bnip3l #mitochondria #metabolismresearch #calciumsignaling #skeletalmuscle #muscleregeneration #organellequalitycontrol #celldeath #cellstress #mitomedicine… | Sa...
New Study Reveals BNIP3L as a Central Guardian of Muscle Identity, Metabolism, and Calcium Signaling I am pleased to share the publication of a study I had the privilege to co-author alongside Profess...
www.linkedin.com
December 9, 2025 at 11:33 PM
jprnews.bsky.social
“CDPKs as Ca2+ signaling decoders in guard cell signaling.” Mori #OpenAccess #Review #GuardCell #Stomata #CalciumSignaling link.springer.com/article/10.1...
CDPKs as Ca2+ signaling decoders in guard cell signaling - Journal of Plant Research
Journal of Plant Research - Stomatal movements are essential for balancing photosynthetic carbon dioxide uptake with water conservation and defense against pathogens. These processes are controlled...
link.springer.com
May 5, 2026 at 1:58 AM
embo.org
Explore plant #CalciumSignaling in the eponymous EMBO Workshop in Primosten, Croatia, 20–24 September 2026.

Abstract submission deadline: 30 May 2026
Registration deadline: 31 May 2026

https://meetings.embo.org/event/26-calcium-signaling
#EMBOCalciumSignaling #conference #meeting #EMBOevents 🧪
May 19, 2026 at 1:40 PM
embo.org
Explore plant #CalciumSignaling in the eponymous EMBO Workshop "Plant calcium signaling" in #Primosten, Croatia, 20–24 September 2026.

Abstract submission deadline: 1 May
Registration deadline: 31 May

https://meetings.embo.org/event/26-calcium-signaling
#EMBOCalciumSignaling #EMBOevents 🧪
January 22, 2026 at 9:40 AM
helenehalkjaer.bsky.social
We're RECRUITING 🎉 Come to Denmark and help us better understand the functional consequences of calmodulin mutations! 🔎

We're looking for postdoc candidates experienced in calciumsignaling🌟, neuroscience🧠, cardiology🫀, biophysics⚡, or cellbiology🧫

More here: www.vacancies.aau.dk/scientific-p...
ONE OR MORE POSTDOCS IN CALCIUM/CALMODULIN SIGNALING
Human calmodulin mutations cause cardiac arrhythmia but have recently also been linked to neurodevelopmental disorders. While we have established a good foun...
www.vacancies.aau.dk
March 6, 2025 at 8:23 PM
pjsaez.bsky.social
This is why we love #CalciumSignaling

Look how mechanical damage triggers long range Ca2+ waves in this plant !!
By @annalisabellandi.bsky.social, who is now around here ;)

Full www.science.org/doi/10.1126/... @science.org #microscopy #cell #mechanobiology 🧪🔬
March 16, 2026 at 8:59 PM
pjsaez.bsky.social
Very hot from the press !

Almost every topic we work in:
#IonChannels #Leukocytes #CalciumSignaling

T cell response depends on target-cell stifness to drive Piezo1- Orai1 membrane channels activation, softening of tumours prevents this response.

Full www.science.org/doi/10.1126/... @science.org
T cell polarization and NFAT activation are stiffness dependent and differentially regulated by the channels PIEZO1 and ORAI1
Target stiffness influences T cell polarization and gene expression through distinct Ca2+ channels.
www.science.org
January 27, 2026 at 8:17 PM
pjsaez.bsky.social
Excellent, kudos @goetzjacky.bsky.social
#CalciumSignaling everywhere 🔥
December 30, 2024 at 9:27 AM
pjsaez.bsky.social
#CellMigration& #CalciumSignaling 🔬🧪
Years ago we showed that ATP acts as danger signal & speed up dendritic cells (DCs) by activating P2X7 & Panx1 channels www.science.org/doi/full/10....

Now we show that CACNB3 can also do the job, & it's a marker for migratory DCs
www.science.org/doi/10.1126/...
The image shows a graph on the left, in which data represents an increase in speed upon ATP treatment only in wild type mice derived dendritic cells, a type of leukocyte. Only a mild increase in speed is observed in cells lacking CACNB3 channel. An on the right the picture shows 4 panels of density map in which actin distribution is shown. ATP relocalizes actin at the cell rear in wild type but this doesn't occur in dendritic cells lacking CACNB3.
September 20, 2023 at 9:27 PM
febsj.bsky.social
🔦 We're delighted to highlight this brilliant study shedding light on a new mechanism in starvation-induced calcium signaling.
📕 A perilysosomal feedforward mechanism regulates starvation-induced calcium signaling ➡️ buff.ly/Zsyhj0c
#starvation #calciumsignaling #perilysosome #TRPML1 #SICS
May 12, 2026 at 1:00 PM
fabmusacchio.bsky.social
🧠 New paper by Chiu et al: #SST #interneurons do not only suppress #dendritic signaling. Via tonic activation of α5 #GABA receptors they can paradoxically enhance AP-evoked dendritic #CalciumSignaling in #cortical #pyramidal #neurons.

🌍 https://doi.org/10.1016/j.neuron.2026.04.017

#Neuroscience
Figure 1 Tonic GABAergic signaling enhances action potential-evoked dendritic calcium transients (A) Representative voltage-clamp recordings before (black) and after (red) flow-in of 10 μM gabazine (Gbz). (B) Example histogram of current values during a 3-s recording under control (black) and post-Gbz (red) conditions. Thin lines show the corresponding one-sided Gaussian curve-fits for identifying phasic and tonic currents. The difference in Gaussian peak locations indicates change in tonic current after Gbz application. (C) Population data (mean and values for individual cells) showing change in currents induced by control ACSF, Gbz, TB21007 (TB), RO4938581 (RoNAM), and RO7015738 (RoPAM). (Left) Change in tonic holding current. (Right) Change in phasic current measured as area under the curve (AUC). ∗ indicates p < 0.05 relative to baseline, by Wilcoxon matched-pairs test. (D) Representative image showing the recording configuration. Layer 2/3 PNs from the mouse prefrontal cortex were filled through the patch pipette with Alexa Fluor 594 and Fluo 5F and imaged using 2-photon laser-scanning microscopy (left). Somatic APs were evoked via somatic current injection, producing brief dendritic calcium transients in spines and neighboring shafts (dashed line indicates line-scan), which are visible as a rise in green fluorescent signal (right). (E) Average AP waveform under baseline conditions (black) and after flow-in of Gbz (red). (F) Average AP-evoked spine ΔCa2+ under baseline conditions (black) and after flow-in of Gbz (red, left traces) or ACSF (gray, right traces). Lines and shaded regions indicate mean ± SEM. (G) Average AP-evoked spine ΔCa2+ under baseline conditions (black) and after flow-in of RoNAM (left, green) or RoPAM (right, purple). Lines and shaded regions indicate mean ± SEM. (H) Population data (mean and values for individual spines and dendrites) showing change in ΔCa2+ induced by flow-in of ACSF, Gbz, Gbz at 32°C, 20 nM Gbz, picrotoxin (Ptx), RoNAM, or RoPAM. ∗ indicates p < 0.05 relative to baseline, by linear mixed-effects model. Figure 2 Tonic GABAergic signaling deinactivates dendritic low-threshold voltage-gated calcium channels (A) Computational modeling data illustrating dendritic voltage (Vm), calcium current (ICa2+), high- and low-threshold calcium channel conductance (gHVA, gLVA), and low-threshold channel activation and inactivation fraction (mLVA, hLVA) in response to a somatic AP under control conditions (black) and following elimination of tonic GABA conductance (red). (B) Heatmap of model data showing change in ΔCa2+ relative to baseline as a function of dendritic location (distance from soma) and somatic membrane potential caused by removal of the tonic GABA conductance. (C) Model data showing change in ΔCa2+ relative to baseline (200 μm location) after removal of tonic GABA, for varying shifts in the LVA voltage-dependent inactivation curve. Data are for models including only HVA (light blue) or LVA (dark blue) channels. (D) (Upper graph) Experimental population data (mean values for individual spines) showing the magnitude of ΔCa2+ for different values of somatic membrane voltage adjusted via intracellular current injection (top). Numbers indicate fractional change in ΔCa2+ for each 10-mV step. (Lower graph) Experimental population data (values for individual spines) showing change in ΔCa2+ induced by flow-in of Gbz as a function of dendritic distance from the soma. Dashed line is the linear fit of the values of individual spines. (E) Average AP-evoked spine calcium transients before (blue) and after (red) application of Gbz. Data are shown for pre-incubation with HVA (left) or LVA (right) channel blockers. Lines and shaded regions indicate mean ± SEM. (F) Population data (mean and values for individual spines) showing change in ΔCa2+induced by flow-in of Gbz in the presence of ACSF, HVA-type calcium blockade, or LVA-type channel blockade. ∗ indicates p < 0.05 relative to baseline, by linear mixed-effects model. Figure 5 Tonic GABAergic signaling enhances depolarization-induced suppression of inhibition (A) Schematic showing experimental setup for induction of DSI. Whole-cell recordings of layer 2/3 PNs were paired with optical stimulation of SST-INs. DSI was induced by a brief train of somatic APs. (B) Average AP burst-evoked calcium transients from dendritic spines before (black) and after (red) application of 20 nM Gbz. Lines and shaded regions indicate mean ± SEM. (C) Population data (mean and values for individual spines) showing burst-evoked change in ΔCa2+ following application of Gbz. ∗ indicates p < 0.05, by linear mixed-effects model. (D) Example IPSCs evoked by optical stimulation of SST-INs recorded before (pre) or after (post) DSI induction for either baseline conditions (black) or after flow-in of 20 nM Gbz (red). (E) Average (± SEM) time course of normalized SST-IN-evoked IPSC amplitude before and after DSI induction, recorded under baseline conditions (black) and after flow-in of 20 nM Gbz (red). Gray boxes show time intervals for calculating pre- and post-IPSC amplitudes. (F) Population data (values for individual cells) showing amount of DSI (percentage pre-induction IPSC amplitude) before (black) or after (red) Gbz flow-in. ∗ indicates p < 0.05 relative to baseline, by Wilcoxon matched-pairs test. (G) Population data (mean and values for individual cells) showing amount of DSI in the presence of the T-type calcium channel blocker TTA-A2 (TTA). (H) Example IPSCs evoked by optical stimulation of SST-INs recorded before (pre) or after (post) DSI induction for either baseline conditions (black) or after flow-in of RoNAM (green). (I) Average (±SEM) time course of normalized SST-IN-evoked IPSC amplitude before and after DSI induction, recorded under baseline conditions (black) and after flow-in of RoNAM (green). (J) Population data (values for individual cells) showing amount of DSI (percentage pre-induction IPSC amplitude) before (black) or after RoNAM flow-in. ∗ indicates p < 0.05 relative to baseline, by Wilcoxon matched-pairs test. (K) Example IPSCs evoked by optical stimulation of SST-INs recorded before (pre) or after (post) DSI induction for either baseline conditions (black) or after flow-in of RoPAM (purple). (L) Average (±SEM) time course of normalized SST-IN-evoked IPSC amplitude before and after DSI induction, recorded under baseline conditions (black) and after flow-in of RoPAM. (M) Population data (values for individual cells) showing amount of DSI (percentage pre-induction IPSC amplitude) before (black) or after RoPAM flow-in. ∗ indicates p < 0.05 relative to baseline, by Wilcoxon matched-pairs test.
May 20, 2026 at 5:46 PM
braincase.bsky.social
#Calcium signals recording is a technique that uses calcium indicators to detect the concentration of calcium ions within tissues.
🧠We will provide a detailed introduction to 8 red calcium sensors
👇👇
www.ebraincase.com/support/lite...

#CalciumSignaling
#NeuroscienceResearch
#RedCalciumSensors
March 25, 2025 at 1:41 AM
cellcommlab.bsky.social
re-intro to #BSky 🧪🔬

We are the Cell Communication & Migration laboratory (CellComM lab)

We use #microscopy to study organelle, cytoskeleton, & signaling dynamics, and cellular interactions during motility

#organelles #cellmigration #calciumsignaling #cellcomm #scicomm @focalplane.bsky.social
December 17, 2024 at 8:26 AM
physiologyjapan.bsky.social
🧠 Just published online in JPS❣️
“Simultaneous in vivo imaging of Ca²⁺ signals in periarteriolar cholinergic axonal varicosities and arteriolar diameter changes in the mouse cerebral cortex”
— Nobuhiro Watanabe et al.
🔗 doi.org/10.1016/j.jp...
#CerebralCortex #CalciumSignaling #CerebralBloodFlow
August 20, 2026 at 3:23 AM
physiologyjapan.bsky.social
🧠 Just published online in JPS❣️
“Involvement of interaction between TRPM2 and IKCA1 in temperature-dependent movement and IL-1β production in mouse microglia”
— Aykut Deveci et al.
🔗 doi.org/10.1016/j.jp...
#Microglia #TRPM2 #CalciumSignaling #Neuroinflammation #NowOnline #JPhysiolSci
Redirecting
doi.org
May 7, 2026 at 12:59 AM