Dmytro Vasylyev, Sidharth Tyagi, Stephen G. Waxman et al. @yaleschoolofmed.bsky.social show that Nav1.7 and Nav1.8 #sodiumchannels work cooperatively to control sensory-neuron excitability. rupress.org/jgp/article/...

#Biophysics #MolecularPhysiology #ComputationalBiology #Nerve #IonChannels

Why do females prefer warmer temperatures than males? Study in mice points to two temperature sensors @jphysiol.bsky.social.

Read more about the research identifying the molecular basis for the different thermal sensations in females and males 🗞️ buff.ly/jk3GkNF

#IonChannels

In @jgp.org, Vasylyev, Tyagi, Waxman et al. @yaleschoolofmed.bsky.social show that Nav1.7 and Nav1.8 #sodiumchannels work cooperatively to control sensory-neuron excitability. rupress.org/jgp/article/...

#Biophysics #MolecularPhysiology #ComputationalBiology #Nerve #IonChannels

📣 Call for Papers ⏰ DEADLINE: November 30!
JGP welcomes submissions that focus on increasing our understanding of the role of voltage-gated sodium channels in the broad physiological and pathophysiological context.
👉 rupress.org/jgp/pages/ca...

#IonChannels #CallForPapers #WSCC26

Early disruptions in brain capillary blood flow control in a mouse model of #Alzheimers disease. New study from Ashwini Hariharan, Thomas A. Longden and colleagues @medschool.umaryland.edu: rupress.org/jgp/article/...

#IonChannels #Pathophysiology #SystemsPhysiology

Magnesium sits inside your NMDA receptor channel like a cork in a bottle, preventing neurons from firing randomly. When magnesium runs low, this safety gate…

#Ionchannels #Magnesium #Neurologicalhealth #Neuroscience #NMDAreceptor

#Ionchannels #Magnesium #Neurologicalhealth #Neuroscience #NMDAre…

Hariharan, Longden et al. @medschool.umaryland.edu show that in a mouse model of #Alzheimers disease, capillary blood flow control fails early: endothelial Kir2.1 currents decline at 2–4 mo, followed by pericyte KATP channel impairment by 6–8 mo. rupress.org/jgp/article/...

#IonChannels

🚀 Worldwide Sodium Channel Seminars are back for Season 4!

Starts Nov 3 with talk from Samantha Salvage on cardiac Nav: "Targeting the cardiac sodium channel and its alternatively spliced variants with fragment antibodies"

Program & link to connect: lnkd.in/e7TRu8Hn

#SodiumChannels #IonChannels

In @jgp.org, Hariharan, Longden et al. @medschool.umaryland.edu show that in a mouse model of #Alzheimers disease, capillary blood flow control fails early: endothelial Kir2.1 currents decline at 2–4 mo, followed by pericyte KATP channel impairment by 6–8 mo. rupress.org/jgp/article/...
#IonChannels

📣 Call for Papers ⏰ DEADLINE NOVEMBER 30, 2026 📣 We welcome papers on Voltage-Gated Sodium Channels for a special issue, initiated in the context of the second Worldwide Sodium Channel Conference #WSCC26. Submit here 👉 rupress.org/jgp/pages/ca...

#IonChannels #CallForPapers

🧪💊☝️ #ionchannels #neuroskyence

Grateful for funding by @DFF @novo-nordisk.bsky.social @lundbeckfonden.bsky.social

#ProteinDesign #DeNovoDesign #IonChannels #Stroke #CryoEM #Electrophysiology #DrugDiscovery

👁️ Light-sensitive cells can also respond to acidity. A recent study highlights functional acid-sensing ion channels in cultured primate rods and cones, adding to our understanding of retinal cell physiology.

👉 doi.org/10.1007/s004...

#Physiology #Retina #ASICs #IonChannels #Vision

Very excited about every single one of the five abstracts that my group has been involved in that were submitted for the BPS 2027 meeting in Philly!

#BPS2027 #biophysics #ionchannels

📣 Call for Papers ⏰ DEADLINE EXTENDED: November 30 📣 JGP welcomes submissions that focus on increasing our understanding of the role of voltage-gated sodium channels in the broad physiological and pathophysiological context. 👉 rupress.org/jgp/pages/ca...

#IonChannels #CallForPapers #WSCC26

State-dependent inhibition of LRRC8 volume-regulated anion channels by DCPIB. New study from Toshiki Yamada, Erkan Karakas, and Jerod S. Denton @vanderbilt.edu:
rupress.org/jgp/article/...

#MolecularPharmacology #MembraneTransport #IonChannels

A fluorescent non-hydrolyzable probe for the nucleotide binding sites of KATP. New study from Priscilla Rubio, Michael C. Puljung and coleagues @trinitycollege.bsky.social:
rupress.org/jgp/article/...

#Biochemistry #Biophysics #MolecularPhysiology #CellularPhysiology #IonChannels