#CardiacFunction
🫀 Just published online in JPS❣️
"Xanthine oxidase inhibitor allopurinol preserves cardiac function after experimental malocclusion induced by occlusal disharmony in mice"
-- Takao Mitsubayashi et al.
🔗 [https://doi.org/10.1016/j.jphyss.2025.100029]
#CardiacFunction #Allopurinol #Malocclusion
July 3, 2025 at 3:38 AM
Repost
[Publication] Happy to share Dr Renault and
Dr Cornuault's new publication in which they demonstrated that #cardiacpericytes are essential for maintaining #cardiacfunction, directly modulating cardiomyocyte properties and preventing cardiac inflammation. www.ahajournals.org/doi/full/10....
Partial Mural Cell Ablation Disrupts Coronary Vasculature Integrity and Induces Systolic Dysfunction | Journal of the American Heart Association
www.ahajournals.org
April 25, 2025 at 11:49 AM
#HFpEF lacks effective treatments.
This study identifies S100A9 as a key driver of oxidative stress and mitochondrial dysfunction, revealing a promising therapeutic target for improving #CardiacFunction. #SIRT3
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
September 1, 2026 at 5:10 PM
This study demonstrates that #Qiliqiangxin may rebalance #Inflammatory #Cytokines in patients with #DilatedCardiomyopathy, and that combining it with standard anti-#HeartFailure medications could further improve #CardiacFunction. #medsky

To read: doi.org/10.1007/s115...
March 20, 2026 at 2:45 AM
❤️ Heart health: Drinking ketones may help improve function

People with type 2 diabetes who were given ketones before exercise had increased cardiac output, stroke volume, and peripheral muscle oxygenation, which are all indicators of improved heart.#HeartHealtha#KetonesBenefitsf#CardiacFunctiontion
Heart health: Drinking ketones may help improve function
People with type 2 diabetes who were given ketones before exercise had increased cardiac output, stroke volume, and peripheral muscle oxygenation, which are all indicators of improved heart function.
www.medicalnewstoday.com
February 16, 2025 at 10:04 AM
Investigation of roles of #PDGF and #TGFβ signaling in right ventricular #fibrosis, using the dual inhibitor, #Tranilast, reports reduced RV #hypertrophy and improved diastolic relaxation, implicating both growth factors as relevant targets.
doi.org/10.14814/phy...
#Cardiovascular #CardiacFunction
doi.org
May 8, 2025 at 9:02 AM
Intracellular #cholesterol imbalance drives #DilatedCardiomyopathy by disrupting sarcomere–ER contact site signaling and ER remodelling, while restoring cholesterol homeostasis rescues cellular architecture and improves #cardiacfunction. @uni-goettingen.de
#OpenAccess: doi.org/10.1038/s413...
June 21, 2026 at 8:01 AM
This review describes the relationship between #mtDNA integrity and #CardiacFunction, the associated regulatory pathways and the mechanisms driving #MitochondrialDysfunction and #Ischemia/#Reperfusion-induced cardiomyocyte injury. #medsky

#OpenAccess: doi.org/10.1016/j.ge...
January 14, 2026 at 1:25 AM
HIIT Boosts Heart Health at the Molecular Level
High-intensity interval training elevates meteorin-like protein, improving cardiac function via the AMPK/HDAC4 signaling axis. doi.org/10.1016/j.ge...
#ExerciseScience #HIIT #CardiacFunction #MolecularPathways
June 3, 2025 at 10:19 AM