Strain richness of gut microbiota ecosystems is a key characteristic underpinning engraftment in faecal microbiota transplantation, and could improve the design of defined live biotherapeuti...

Here, the authors profile bacterial engraftment in UC patients receiving FMT from a single donor and placebo samples to estimate noise, showing a significant level of false-positive engraftment, which...

Strain richness of gut microbiota ecosystems is a key characteristic underpinning engraftment in faecal microbiota transplantation, and could improve the design of defined live biotherapeuti...

Strain richness of gut microbiota ecosystems is a key characteristic underpinning engraftment in faecal microbiota transplantation, and could improve the design of defined live biotherapeutic…

Strain richness of gut microbiota ecosystems is a key characteristic underpinning engraftment in faecal microbiota transplantation, and could improve the design of defined live biotherapeuti...

‘Engraftment of patient-derived xenografts in samples from head and neck squamous cell carcinoma is variable. Here, the authors use transcriptomic and proteomic profiling to correlate engraftment of P...

Kowala et al. demonstrate a clinically relevant transplantation strategy synergizing engineered human myogenic cells and hydrogel-mediated delivery in a dystrophic mouse model. Upon long-term engraftm...

Adaptable human blood vessel cells enable functional engraftment of pancreatic islets under the skin to treat diabetes.

SC-β and SC-MReg coaggregates have improved insulin secretion, metabolic function, and reverse hyperglycemia in diabetic mice.

Our systematic review with meta-analysis suggests that discontinuation of quinolone prophylaxis during pre-engraftment neutropenia reduces bacterial resist

In this issue, Chadarevian et al. showed that engraftment of human iPSC-derived microglia (iMG) engineered to express secreted neprilysin (sNEP) under the plaque-responsive CD9 promoter reduces amyloi...

Endo et al. show that preserving the intestinal niche enables near-complete engraftment of ileal organoids in the jejunum. The resulting ilealized segment restores bile acid absorption and improves survival in short bowel syndrome, suggesting a path toward region-targeted, autologous regenerative therapy.

In this cohort study of adult allo-HCT recipients at Memorial Sloan Kettering Cancer Center in New York between 2017 and 2022, eligible participants had been admitted for Allo-HCT. Three times weekly, patients who had been recently admitted for allo-HCT were invited to participate in dietary-intake collection. Neutrophil engraftment was defined as the first of 3 days of neutrophil count ≥500 per μl. Five patients died without achieving engraftment and were excluded from the analysis of median time to engraftment. No patients were lost to follow-up. For mortality analysis, one patient died before landmark day 12 and was excluded from that analysis. The latest follow-up/data collection date was in April 2023. Nutrition data collection and annotation The hospital kitchen commercial computer system (Computrition) was configured to provide a printout that accompanied each meal tray to the bedside on which patients were asked to indicate, immediately after each meal, whether they consumed 0, 25%, 50%, 75% or 100% of each item they ordered for that meal. These instruments were collected by a dietician or other research team members three times weekly, during which missing entries were completed at the bedside along with encouragement to sustain motivation with the project. Consumption data were...