#ImmuneCheckpointInhibitors
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castltrastondrs.medsky.network
#Medsky🧪 #oncosky #pharmasky #publichealth #Immunecheckpointinhibitors improve cancer survival but can trigger immune related adverse events. Among these, #fulminantmyocarditis is an often fatal complication with limited therapies. This study makes a very important discovery
Graphic abstract
February 23, 2026 at 4:55 AM
oncodaily.bsky.social
What Are the Signs That Immunotherapy Is Working?

oncodaily.com/oncolibrary/...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #Immunotherapy #IO #ImmuneCheckpointInhibitors #ImmuneRelatedSideEffects #ICIs #Pseudoprogression
What Are the Signs That Immunotherapy Is Working? - OncoDaily
Signs immunotherapy is working may include tumor shrinkage, stable scans, or symptom relief. Learn what to expect and how to recognize if treatment is effective.
oncodaily.com
April 16, 2025 at 9:46 PM
castltrastondrs.medsky.network
#Medsky🧪 #oncosky #cardioncology In real life Diagnosis and management of #Immunecheckpointinhibitors -induced #myocarditis following #cancertherapy
www.sciencedirect.com/science/arti...
Real life management of elevated troponin in patients treated with immune checkpoint inhibitors
Immune checkpoint inhibitors (ICIs) have revolutionized the clinical outcomes of cancer. Nevertheless, their use may lead to myocardial injury. The 20…
www.sciencedirect.com
February 15, 2025 at 6:05 PM
castltrastondrs.medsky.network
MedSky🧪 #Immunotherapy #Gutmicrobiome & #Cancerimmunotherapy The #gutmicrobiota influences anti-tumor #immunity & can induce or inhibit response to #immunecheckpointinhibitors
abstract
March 28, 2024 at 10:55 AM
oncodaily.bsky.social
PD-1/VEGF combos are a strategy to watch in lung cancer - Amy Moore
@acmoorephd.bsky.social

oncodaily.com/insight/amy-...

#Cancer #ImmuneCheckpointInhibitors #LungCancer #Health #NSCLC #OncoDaily #Oncology #Medicine
Amy Moore: PD-1/VEGF combos are a strategy to watch in lung cancer - OncoDaily
Amy Moore: PD-1/VEGF combos are a strategy to watch in lung cancer / Amy Moore, cancer, Immune Checkpoint Inhibitors, Keiju Aokage, Lung cancer, Masahiro
oncodaily.com
January 6, 2025 at 4:32 PM
castltrastondrs.medsky.network
MedSky🧪#Drugsdevelopment Various #immunecheckpointinhibitors are approved as adjuvant therapies for high-risk #melanoma (stage IIB–IV), but disease recurrence remains common.
February 23, 2024 at 7:01 AM
stevenartandi.bsky.social
Stanford's Fauzia Riaz & others found poor outcomes for hospitalized cancer patients treated with #ImmuneCheckpointInhibitors. Caution is advised for inpatient use.
ascopubs.org
April 14, 2025 at 4:06 PM
oxcio.bsky.social
🚨 Check out this excellent #review by Nacho Melero and Maria Aggelakopoulou from @oxcio.bsky.social on the role of cDC1 in #cross-priming CD8+ Tcells in tumors and how strategies like FLT3L, which boost cDC1, may support immunotherapy success.
👇🔬
#CancerImmunotherapy #DCs #ImmuneCheckpointInhibitors
natrevcancer.nature.com Nature Reviews Cancer @natrevcancer.nature.com · Feb 11
Melero&Co discuss the crucial role of conventional type 1 dendritic cells in cross-presenting antigens to prime CD8+ T cells to mount anti-tumour immunity and highlight how this can be exploited for #CancerImmunotherapy
@unav.edu
📖 ⬇️
Cross-priming in cancer immunology and immunotherapy - Nature Reviews Cancer
www.nature.com
February 12, 2025 at 11:50 AM
endosocjournals.bsky.social
Concomitant Immune Checkpoint Inhibitors Induced Central and Primary Adrenal Insufficiency: A Diagnostic Challenge. Read more in #JCEMCaseReports: bit.ly/42UM6pd #ImmuneCheckpointInhibitors #Hypophysitis #Adrenalitis
November 10, 2025 at 9:02 PM
oncodaily.bsky.social
Bispecific Antibodies VS Immune Checkpoint Inhibitors in Oncology: Mechanisms, Clinical Progress, and Future Directions

oncodaily.com/oncolibrary/...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #BispecificAntibodies #ImmuneCheckpointInhibitors #ICIs #IO #Immunotherapy
Bispecific Antibodies VS Immune Checkpoint Inhibitors in Oncology: Mechanisms, Clinical Progress, and Future Directions - OncoDaily
Explore how bispecific antibodies and checkpoint inhibitors differ in mechanism, efficacy, toxicity, and resistance in modern cancer immunotherapy.
oncodaily.com
August 9, 2025 at 10:40 AM
drjkyl.bsky.social
Machine Learning Model Integrating CT Radiomics of the Lung to Predict Checkpoint Inhibitor Pneumonitis in Patients with Advanced Cancer
@journals.sagepub.com @tcrtcancer.bsky.social

journals.sagepub.com/doi/10.1177/...

#artificialintelligence #adverseevent #immunecheckpointinhibitors #openaccess
May 29, 2025 at 10:04 PM
meduniwien.ac.at
📌 #ImmuneCheckpointInhibitors are revolutionising #cancertreatment:

A #MedUniVienna study, conducted at #CCCVienna, shows: In #rectalcancer, combining #immunotherapy with #chemoradiotherapy can surprisingly often cause severe #myositis. Further information on the study! ⬇️
Increased risk of muscle damage when combining immunotherapy and chemoradiation in rectal cancer
More about the recent study!
ccc.meduniwien.ac.at
July 9, 2025 at 10:29 AM
nephtimes.bsky.social
The findings of a recent study emphasize the need to carefully monitor and evaluate kidney function in patients treated with proton pump inhibitors and immune checkpoint inhibitors. #nephrology #nephsky #kidney #PPIs #protonpumpinhibitors #immunecheckpointinhibitors
Proton Pump Inhibitors, Immune Checkpoint Inhibitors, and AKI  | Docwire News
A study assessed acute kidney injury (AKI) risk with proton pump inhibitor (PPI) use in patients with cancer who received immune checkpoint inhibitors.
buff.ly
January 15, 2025 at 6:30 PM
endosocjournals.bsky.social
Multigland dysfunction from immune-checkpoint inhibitors: a case of hypothyroidism, diabetes, and adrenal insufficiency. Read more in #JCEMCaseReports: https://bit.ly/48v72pI #ImmuneCheckpointInhibitors #Nivolumab #hypothyroidism @endocrinesociety.bsky.social
Multigland dysfunction from immune-checkpoint inhibitors: a case of hypothyroidism, diabetes, and adrenal insufficiency
Abstract. Immune-checkpoint inhibitors (ICIs) such as nivolumab and ipilimumab have improved outcomes in metastatic renal cell carcinoma (RCC) but can caus
bit.ly
May 13, 2026 at 9:49 PM
actamedport.bsky.social
AMP just published!
"Immune Checkpoint Inhibitor-Induced Thyroidal, Pancreatic, and Pituitary Dysfunction: Diagnostic Challenges in a Cancer Patient"

Full paper here:
www.actamedicaportuguesa.com/revista/inde...

#endocrinediseases #immunecheckpointinhibitors #autoimmune #actamedicaportuguesa
November 28, 2025 at 9:50 AM
drmarklythgoe.bsky.social
Our thoughts on the evolving #posology of #Immunecheckpointinhibitors in
@trends in #Cancer

www.cell.com/trends/cance...
The evolving posology and administration of immune checkpoint inhibitors: subcutaneous formulations
Immune checkpoint inhibitors (ICIs) have transformed cancer care. Recently, atezolizumab gained its first global approval in a subcutaneous (SC) formulation by the UK medicines regulator, being notable as the first time an FDA- and/or European Medicines Agency (EMA)-approved ICI has been licensed via this administration route. Here, we discuss this approval, other SC ICIs in development, and the benefits and challenges of this administration route, including potential implications for patient care.
www.cell.com
December 29, 2024 at 2:49 PM
bionewscentral.com
A new #AI model called COMPASS uses #tumor #GeneExpression data to predict which patients will respond to #CancerImmunotherapy with #ImmuneCheckpointInhibitors.
#ArtificialIntelligence
AI tool improves prediction of who will respond to cancer immunotherapy drugs – BioNews Central
A new AI model called COMPASS uses tumor gene expression data to predict which patients will respond to cancer immunotherapy with immune checkpoint inhibitors. ...
sbee.link
July 4, 2026 at 10:30 PM
newswise.bsky.social
Analysis of New Colorectal Cancer Immunotherapy Shows More Treatment Options
www.newswise.com/articles/ana...
#Cancer #colorectalcancer #immunology #ImmuneCheckpointInhibitors #metastaticcancer
Analysis of New Colorectal Cancer Immunotherapy Shows More Treatment Options | Newswise
A team of researchers from Cleveland Clinic Genomic Medicine share insights from an early set of 19,000 patients to receive immune checkpoint inhibitor treatments for colorectal cancer in the U.S. ...
www.newswise.com
March 21, 2025 at 3:39 AM
scienceopen.bsky.social
🔬📄 'Impact of Helicobacter pylori on Immune Checkpoint Inhibition in Hepatocellular Carcinoma: A Multicenter Study' - a @kargerpublishers.bsky.social: #Gastroenterology article on #ScienceOpen -

🖇️ #HelicobacterPylori #HCC #ImmuneCheckpointInhibitors #ImmunotherapyResistance
Impact of <i>Helicobacter pylori</i> on Immune Checkpoint Inhibition in Hepatocellular Carcinoma: A Multicenter Study
<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d7351057e459"> <b> <i>Introduction:</i> </b>...
www.scienceopen.com
August 22, 2025 at 9:57 AM
bionewscentral.com
#DSerine, a non-standard #AminoAcid involved in #CellularSignaling, suppresses cytotoxic #TCell activity in #GastricCancer #tumors and may contribute to resistance against #ImmuneCheckpointInhibitors.
#ImmuneEvasion #ImmunotherapyResistance
D-serine promotes tumor growth in gastric cancer – BioNews Central
D-serine, a non-standard amino acid involved in cellular signaling, suppresses cytotoxic T-cell activity in gastric cancer tumors and may contribute to resistance against immune checkpoint inhibitors. ...
sbee.link
August 10, 2026 at 7:55 PM
genesndiseases.bsky.social
A new study reveals the cell types that potentially affect #ImmuneCheckpointInhibitors (ICIs) and identifies potential drugs by combining bulk sequencing and single-cell sequencing, thus providing hope for ICI treatment in #HCC.

#OpenAccess: https://buff.ly/4h2ocgy
Comprehensive analysis of immune subtype characterization on identification of potential cells and drugs to predict response to immune checkpoint inhibitors for hepatocellular carcinoma
January 21, 2025 at 5:15 PM
genesndiseases.bsky.social
A new study reveals the cell types that potentially affect #ImmuneCheckpointInhibitors (ICIs) and identifies potential drugs by combining bulk sequencing and single-cell sequencing, thus providing hope for ICI treatment in #HCC.

#OpenAccess: www.sciencedirect.co...
Comprehensive analysis of immune subtype characterization on identification of potential cells and drugs to predict response to immune checkpoint inhibitors for hepatocellular carcinoma
January 10, 2025 at 4:00 PM
jamanetworkopen.com
Among patients receiving #ImmuneCheckpointInhibitors, systemic glucocorticoid immunosuppression near initiation, at higher doses, and longer durations was associated with shorter overall survival, regardless of indication.

ja.ma/4fIpNdo
Two survival probability graphs. Top: MGBD cohort, Bottom: TriNetX cohort. Both show survival probability over time (0-36 months) for a control group and five treatment groups [-1, 1], [-2, 2], [-3, 3], [-6, 6], [-12, 12], [-18, 18]. P < .001.
May 24, 2026 at 2:00 PM
sigtrans-sttt.bsky.social
#GutMicrobiota synergizes with #ImmuneCheckpointInhibitors to reprogram the #TumorMicroenvironment by reshaping #macrophages and T cells, converting Spp1⁺ protumor TAMs into antigen-presenting Cd74⁺ TAMs and restoring CD8⁺ T cell function.

#OpenAccess #STTT: doi.org/10.1038/s413...
Single-cell transcriptomic analysis reveals gut microbiota-immunotherapy synergy through modulating tumor microenvironment - Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy - Single-cell transcriptomic analysis reveals gut microbiota-immunotherapy synergy through modulating tumor microenvironment
doi.org
January 1, 2026 at 5:19 PM
drnimaghadiri.bsky.social
Immune checkpoint inhibitors have revolutionised cancer treatment, but with that comes an expanding spectrum of immune-related adverse events

I spoke about ocular toxicities including dry eye, #uveitis, and the increasingly described VKH-like syndrome.

www.linkedin.com/posts/nimagh...
#dryeye #uveitis #oncology #melanoma #multidisciplinary #ophthalmology #podcast #ophthalmic #immunotherapy #immunooncology #oculartoxicity #meded #immunecheckpointinhibitors #medicaloncology… | Nima G...
𝐅𝐫𝐨𝐦 𝐒𝐤𝐢𝐧 𝐭𝐨 𝐒𝐢𝐠𝐡𝐭: 𝐓𝐡𝐞 𝐢𝐧𝐭𝐞𝐫𝐝𝐢𝐬𝐜𝐢𝐩𝐥𝐢𝐧𝐚𝐫𝐲 𝐀𝐩𝐩𝐫𝐨𝐚𝐜𝐡 𝐭𝐨 𝐈𝐦𝐦𝐮𝐧𝐞-𝐑𝐞𝐥𝐚𝐭𝐞𝐝 𝐀𝐝𝐯𝐞𝐫𝐬𝐞 𝐄𝐯𝐞𝐧𝐭𝐬 𝐟𝐨𝐫 𝐜𝐚𝐧𝐜𝐞𝐫 𝐭𝐫𝐞𝐚𝐭𝐦𝐞𝐧𝐭𝐬. 𝑹𝒆𝒂𝒍-𝒘𝒐𝒓𝒍𝒅 𝒄𝒐𝒍𝒍𝒂𝒃𝒐𝒓𝒂𝒕𝒊𝒐𝒏𝒔 Last week’s excellent Immuno-Oncology Clinical Network Case Conun...
www.linkedin.com
March 31, 2026 at 10:24 AM