New research suggests that regular #PhysicalActivity may lower the risk and severity of #MajorDepression, particularly among people with a #GeneticPredisposition.
#Depression #MajorDepressiveDisorder #Exercise #DepressionRisk
#Depression #MajorDepressiveDisorder #Exercise #DepressionRisk
Physical activity may help buffer genetic risk for depression – BioNews Central
New research suggests that regular physical activity may lower the risk and severity of major depression, particularly among people with a genetic predisposition. ...
sbee.link
October 26, 2026 at 3:53 PM
New research suggests that regular #PhysicalActivity may lower the risk and severity of #MajorDepression, particularly among people with a #GeneticPredisposition.
#Depression #MajorDepressiveDisorder #Exercise #DepressionRisk
#Depression #MajorDepressiveDisorder #Exercise #DepressionRisk
#vestibularmigraine #vertigo #vestibulardisorder #StatusMigrainosus #chronicpain #chronicillness #endometriosis #diabetes #neuropathy #PostherpeticNeuralgia #DegenerativeDiscDisease #RupturedDiscs #sciatica #TMD #GeneralizedAnxietyDisorder #MajorDepressiveDisorder #CPTSD #PTSD
September 24, 2026 at 12:13 AM
🧠 In #MajorDepressiveDisorder, gray matter volume trajectories over 10 years were associated with cumulative illness burden rather than diagnosis alone or acute symptom fluctuations.
ja.ma/46jQsrk
ja.ma/46jQsrk
September 14, 2026 at 6:17 PM
🧠 In #MajorDepressiveDisorder, gray matter volume trajectories over 10 years were associated with cumulative illness burden rather than diagnosis alone or acute symptom fluctuations.
ja.ma/46jQsrk
ja.ma/46jQsrk
I didn't get as much done as I had wanted today, but I did make and edit this video, so at least that's something!
#depression #MajorDepressiveDisorder #MentalHealth #MentalHealthAwareness
#depression #MajorDepressiveDisorder #MentalHealth #MentalHealthAwareness
Depression and lack of motivation
YouTube video by RenDuH
youtube.com
September 8, 2026 at 12:42 AM
I didn't get as much done as I had wanted today, but I did make and edit this video, so at least that's something!
#depression #MajorDepressiveDisorder #MentalHealth #MentalHealthAwareness
#depression #MajorDepressiveDisorder #MentalHealth #MentalHealthAwareness
Is #depression only a #BrainDisorder?
This review shows how the gut, immune, endocrine, and metabolic systems interact with the brain, opening new paths for MDD diagnosis and multi-targeted therapies. #MajorDepressiveDisorder
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
This review shows how the gut, immune, endocrine, and metabolic systems interact with the brain, opening new paths for MDD diagnosis and multi-targeted therapies. #MajorDepressiveDisorder
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
September 1, 2026 at 10:30 PM
Is #depression only a #BrainDisorder?
This review shows how the gut, immune, endocrine, and metabolic systems interact with the brain, opening new paths for MDD diagnosis and multi-targeted therapies. #MajorDepressiveDisorder
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
This review shows how the gut, immune, endocrine, and metabolic systems interact with the brain, opening new paths for MDD diagnosis and multi-targeted therapies. #MajorDepressiveDisorder
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
Older adults with #MajorDepressiveDisorder and comorbid rapid-eye-movement #sleep behavior disorder vs those without the sleep disorder exhibited a distinct neurodegenerative profile and #GutDysbiosis.
https://bit.ly/46ikRWS
https://bit.ly/46ikRWS
Microbiome Profiles Could Help Distinguish MDD From MDD With Comorbid RBD
Gut microbiome profiles can differentiate MDD with comorbid REM sleep behavior disorder from depression alone in older adults.
www.psychiatryadvisor.com
August 25, 2026 at 4:18 PM
Older adults with #MajorDepressiveDisorder and comorbid rapid-eye-movement #sleep behavior disorder vs those without the sleep disorder exhibited a distinct neurodegenerative profile and #GutDysbiosis.
https://bit.ly/46ikRWS
https://bit.ly/46ikRWS
1 factor continues to stand out, yet is still under-recognised in #MentalHealth care: long-chain #Omega3 status
Especially in #MajorDepressiveDisorder, which is often recurrent & disabling, quality of life can be profoundly affected, & physical health risks are often elevated
Especially in #MajorDepressiveDisorder, which is often recurrent & disabling, quality of life can be profoundly affected, & physical health risks are often elevated
August 24, 2026 at 3:07 PM
1 factor continues to stand out, yet is still under-recognised in #MentalHealth care: long-chain #Omega3 status
Especially in #MajorDepressiveDisorder, which is often recurrent & disabling, quality of life can be profoundly affected, & physical health risks are often elevated
Especially in #MajorDepressiveDisorder, which is often recurrent & disabling, quality of life can be profoundly affected, & physical health risks are often elevated
My lab's latest research on the genomics of #majordepressivedisorder and the impact on #adultneurogenesis has just been published with @SpringerNature in @NatureMedicine. Read: rdcu.be/fBfGP and: www.cuimc.columbia.edu/news/depress...
Dysregulated adult hippocampal neurogenesis in major depressive disorders
Nature Medicine - The largest multiomic atlas of the adult human hippocampus identifies disrupted neurogenesis, gene regulation and neural circuits in major depressive disorder, revealing molecular...
rdcu.be
August 21, 2026 at 10:11 PM
My lab's latest research on the genomics of #majordepressivedisorder and the impact on #adultneurogenesis has just been published with @SpringerNature in @NatureMedicine. Read: rdcu.be/fBfGP and: www.cuimc.columbia.edu/news/depress...
My Worst #MentalHealthCrisis
#ClinicalDepression #MajorDepressiveDisorder #ThwartedBelongingness #PerceivedBurdensomeness
www.youtube.com/shorts/w2Hbr...
#ClinicalDepression #MajorDepressiveDisorder #ThwartedBelongingness #PerceivedBurdensomeness
www.youtube.com/shorts/w2Hbr...
My Worst #MentalHealthCrisis #ThwartedBelongingness #PerceivedBurdensomeness #Shorts
YouTube video by Tara Softa
www.youtube.com
August 14, 2026 at 8:04 PM
My brain in therapy: "wtf am I saying? why am I saying this?" #anxiety #stress #majordepressivedisorder
August 13, 2026 at 5:41 PM
My brain in therapy: "wtf am I saying? why am I saying this?" #anxiety #stress #majordepressivedisorder
Among Veterans with #MajorDepressiveDisorder, most received recommended care, including psychotherapy, antidepressant medication, and combination therapy.
However, the percentage receiving no treatment has increased each year between 2011-2025.
ja.ma/45Z1fqw
However, the percentage receiving no treatment has increased each year between 2011-2025.
ja.ma/45Z1fqw
August 13, 2026 at 3:45 PM
Among Veterans with #MajorDepressiveDisorder, most received recommended care, including psychotherapy, antidepressant medication, and combination therapy.
However, the percentage receiving no treatment has increased each year between 2011-2025.
ja.ma/45Z1fqw
However, the percentage receiving no treatment has increased each year between 2011-2025.
ja.ma/45Z1fqw
i hate feeling unique and alone, is there anyone who has #schizoaffectivedisorder or #majordepressivedisorder or #bpd
that wants to talk about it?
bc i relate and understand you guys and i don't want you to feel alone either
that wants to talk about it?
bc i relate and understand you guys and i don't want you to feel alone either
June 6, 2025 at 7:46 AM
i hate feeling unique and alone, is there anyone who has #schizoaffectivedisorder or #majordepressivedisorder or #bpd
that wants to talk about it?
bc i relate and understand you guys and i don't want you to feel alone either
that wants to talk about it?
bc i relate and understand you guys and i don't want you to feel alone either
Cell Journal's recently published Review article in 2025, has been selected as Editor’s Choice.
Full-text: www.celljournal.org/article_7290...
We invite you all to read it and share your thoughts.
#Editorchoice #MajorDepressiveDisorder #Neurogenesis#Neuroprotection#Research#RoyanInstitute
Full-text: www.celljournal.org/article_7290...
We invite you all to read it and share your thoughts.
#Editorchoice #MajorDepressiveDisorder #Neurogenesis#Neuroprotection#Research#RoyanInstitute
February 7, 2026 at 8:31 AM
Cell Journal's recently published Review article in 2025, has been selected as Editor’s Choice.
Full-text: www.celljournal.org/article_7290...
We invite you all to read it and share your thoughts.
#Editorchoice #MajorDepressiveDisorder #Neurogenesis#Neuroprotection#Research#RoyanInstitute
Full-text: www.celljournal.org/article_7290...
We invite you all to read it and share your thoughts.
#Editorchoice #MajorDepressiveDisorder #Neurogenesis#Neuroprotection#Research#RoyanInstitute
Short crying session after dinner this evening. These constant flare-ups are so annoying. Every time I think it's over, it starts again. Ever since the new year started. #MajorDepressiveDisorder #MDD
February 6, 2025 at 10:32 AM
Short crying session after dinner this evening. These constant flare-ups are so annoying. Every time I think it's over, it starts again. Ever since the new year started. #MajorDepressiveDisorder #MDD
The effects of #breastcancer can extend beyond remission. This article discusses #insomnia and #majordepressivedisorder in adult #breastcancersurvivors. #MentalHealth academic.oup.com/sleep/articl...
Insomnia and elevated risk of major depressive disorder in older adult, long-term breast cancer survivors vs a matched cohort
AbstractStudy Objectives. Depression frequently occurs after diagnosis of breast cancer diagnosis. This study examines the incidence of depression and whet
academic.oup.com
February 9, 2026 at 2:00 PM
The effects of #breastcancer can extend beyond remission. This article discusses #insomnia and #majordepressivedisorder in adult #breastcancersurvivors. #MentalHealth academic.oup.com/sleep/articl...
The study highlights CD27 as a potential #Biomarker and #therapeutic target in #MajorDepressiveDisorder, warranting future #clinical validation to advance #PrecisionPsychiatry and improve #PatientOutcomes. #medsky
To read: doi.org/10.1007/s115...
To read: doi.org/10.1007/s115...
May 29, 2026 at 1:30 PM
The study highlights CD27 as a potential #Biomarker and #therapeutic target in #MajorDepressiveDisorder, warranting future #clinical validation to advance #PrecisionPsychiatry and improve #PatientOutcomes. #medsky
To read: doi.org/10.1007/s115...
To read: doi.org/10.1007/s115...
This study shows that lncRNA NPTN-IT1-201 regulates #Inflammation and #Apoptosis to mitigate #MajorDepressiveDisorder (MDD) by targeting BDNF via inhibiting miR-142-5p, making it a potential #TherapeuticTarget for MDD. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
July 9, 2025 at 10:50 AM
This study shows that lncRNA NPTN-IT1-201 regulates #Inflammation and #Apoptosis to mitigate #MajorDepressiveDisorder (MDD) by targeting BDNF via inhibiting miR-142-5p, making it a potential #TherapeuticTarget for MDD. #medsky
Read: link.springer.com/article/10.1...
Read: link.springer.com/article/10.1...
📣Help explore more treatment options for #depression with Cambridge Psychedelic Research Group @cpft-nhs.bsky.social!
They're offering the EMBRACE trial for anyone aged 18-85 diagnosed with #MajorDepressiveDisorder who feels current medication isn't working.
🖐️To join contact: psychedelic@cpft.nhs.uk
They're offering the EMBRACE trial for anyone aged 18-85 diagnosed with #MajorDepressiveDisorder who feels current medication isn't working.
🖐️To join contact: psychedelic@cpft.nhs.uk
July 22, 2026 at 3:54 PM
📣Help explore more treatment options for #depression with Cambridge Psychedelic Research Group @cpft-nhs.bsky.social!
They're offering the EMBRACE trial for anyone aged 18-85 diagnosed with #MajorDepressiveDisorder who feels current medication isn't working.
🖐️To join contact: psychedelic@cpft.nhs.uk
They're offering the EMBRACE trial for anyone aged 18-85 diagnosed with #MajorDepressiveDisorder who feels current medication isn't working.
🖐️To join contact: psychedelic@cpft.nhs.uk
REM density may mark hypofrontality in #MDD and poor #emotionalProcessing in MDD/PTSD.
#Nightmares impair trauma processing in #PTSD & are linked to suicidality in PTSD/MDD.
Targeted therapies for #REM disturbances may enhance #emotionRegulation in mental disorders.
#MajorDepressiveDisorder
#Nightmares impair trauma processing in #PTSD & are linked to suicidality in PTSD/MDD.
Targeted therapies for #REM disturbances may enhance #emotionRegulation in mental disorders.
#MajorDepressiveDisorder
REM sleep and nightmares as transdiagnostic features of psychiatric disorders:
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Systematic review: REM sleep, dysphoric dreams and nightmares as transdiagnostic features of psychiatric disorders with emotion dysregulation - Clinical implications
Fragmented rapid eye movement (REM) sleep disrupts the overnight resolution of emotional distress, a process crucial for emotion regulation. Emotion d…
www.sciencedirect.com
February 23, 2025 at 3:44 PM
REM density may mark hypofrontality in #MDD and poor #emotionalProcessing in MDD/PTSD.
#Nightmares impair trauma processing in #PTSD & are linked to suicidality in PTSD/MDD.
Targeted therapies for #REM disturbances may enhance #emotionRegulation in mental disorders.
#MajorDepressiveDisorder
#Nightmares impair trauma processing in #PTSD & are linked to suicidality in PTSD/MDD.
Targeted therapies for #REM disturbances may enhance #emotionRegulation in mental disorders.
#MajorDepressiveDisorder
My new song “Joyless” is available now. It’s for anyone surviving #depression #majordepression #majordepressivedisorder #ptsd #cptsd #religioustrauma #spiritualtrauma #abuse #mentalhealthconditions
October 20, 2025 at 12:33 PM
My new song “Joyless” is available now. It’s for anyone surviving #depression #majordepression #majordepressivedisorder #ptsd #cptsd #religioustrauma #spiritualtrauma #abuse #mentalhealthconditions
An intro post about my illnesses:
Hospitalized with pneumonia at age 4, sick with asthma and chronic sinusitis through childhood
Dx'd with #fibromyalgia at the age of 15
Dx'd with #MajorDepressiveDisorder at 15
Dx'd with #PanicDisorder at 19
Came down with Mono (EBV) at 19
(Con't)
Hospitalized with pneumonia at age 4, sick with asthma and chronic sinusitis through childhood
Dx'd with #fibromyalgia at the age of 15
Dx'd with #MajorDepressiveDisorder at 15
Dx'd with #PanicDisorder at 19
Came down with Mono (EBV) at 19
(Con't)
November 26, 2024 at 6:01 PM
An intro post about my illnesses:
Hospitalized with pneumonia at age 4, sick with asthma and chronic sinusitis through childhood
Dx'd with #fibromyalgia at the age of 15
Dx'd with #MajorDepressiveDisorder at 15
Dx'd with #PanicDisorder at 19
Came down with Mono (EBV) at 19
(Con't)
Hospitalized with pneumonia at age 4, sick with asthma and chronic sinusitis through childhood
Dx'd with #fibromyalgia at the age of 15
Dx'd with #MajorDepressiveDisorder at 15
Dx'd with #PanicDisorder at 19
Came down with Mono (EBV) at 19
(Con't)
when i stop and think about it, my life actually has been one long disaster, like every single new years eve was like "FUCK that whole year, nowhere but up" and instead it just got worse and worse.
#MajorDepressiveDisorder
#MajorDepressiveDisorder
August 28, 2024 at 6:51 PM
when i stop and think about it, my life actually has been one long disaster, like every single new years eve was like "FUCK that whole year, nowhere but up" and instead it just got worse and worse.
#MajorDepressiveDisorder
#MajorDepressiveDisorder
Single-dose #psilocybin produced a rapid, sustained #antidepressant effect for more than 3 months in adults with #majordepressivedisorder vs placebo.
📖 Catch more details: ja.ma/4eVWkw7
📖 Catch more details: ja.ma/4eVWkw7
July 14, 2026 at 1:00 PM
Single-dose #psilocybin produced a rapid, sustained #antidepressant effect for more than 3 months in adults with #majordepressivedisorder vs placebo.
📖 Catch more details: ja.ma/4eVWkw7
📖 Catch more details: ja.ma/4eVWkw7
Among individuals with #MajorDepressiveDisorder, higher exposure to adverse childhood experiences was associated with increased risk of treatment-resistant depression, even after accounting for shared familial factors. ja.ma/4rwpmFE
March 13, 2026 at 12:00 PM
Among individuals with #MajorDepressiveDisorder, higher exposure to adverse childhood experiences was associated with increased risk of treatment-resistant depression, even after accounting for shared familial factors. ja.ma/4rwpmFE