#Methionine
Whey powder has a much better balance of amino acids than pea protein on its own.
Pea protein will—technically—supply you with a 'complete range' of amino acids, but is way too low in methionine, so ideally would be combined with grain protein, to compensate for that (on the rice and dal principle).
October 12, 2026 at 7:12 PM
🧬 REVIEW 🧬

Plants have low methionine levels. Elevated methionine impacts metabolism, stress responses and epigenetic regulation. Understanding the regulation of methionine content may guide safe nutritional biofortification strategies- Amir et al.

🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
October 10, 2026 at 6:50 PM
→ What they did
Researchers studied how limiting methionine intake affects cellular metabolism, finding it triggers protective responses to nutrient scarcity.
October 10, 2026 at 3:20 PM
Reducing methionine intake activates cellular maintenance processes like autophagy, mirroring the benefits of calorie restriction.

#Methionine #CalorieRestriction #Autophagy
Low methionine intake alters metabolic operation
Source: Fight Aging!
realfeedapp.com
October 10, 2026 at 3:20 PM
🌸🧬 RESEARCH 🧬🌸

Arabidopsis flowers accumulate the sulfur by-product methylthioadenosine when methionine salvage is reduced, lowering methylation capacity and impairing fertility. Short-term spermidine treatment partly restores growth- Tremblay et al.

🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
October 9, 2026 at 9:00 AM
[Q]
what is your favorite amino acid and why?

[A]
Methionine because it is coded for by the start codon (AUG). It's the first amino acid of all polypeptide chains (prior to post-translational processing). Methionine is number 1!

[2007]
October 7, 2026 at 3:08 AM
(JASMS) Mass Spectrometric Analysis of Free Methionine Oxidation
Levels in E. coli: AbstractOxidation
of free methionine plays important roles in cellular
redox homeostasis, yet its accurate quantification has been hindered
by methodological challenges. Here, we introduce free… (RSS) #MassSpecRSS
Mass Spectrometric Analysis of Free Methionine Oxidation Levels in E. coli
AbstractOxidation of free methionine plays important roles in cellular redox homeostasis, yet its accurate quantification has been hindered by methodological challenges. Here, we introduce free methionine oxidation by blocking (fMObB), a mass spectrometry-based method that enables accurate measurement of the fractional oxidation of free methionines. Applying fMObB to E. coli, we quantify free methionine oxidation under basal and oxidative stress conditions and in strains lacking methionine sulfoxide reductases. We found that during oxidative stress, free methionines exhibit higher oxidation levels than protein-bound methionines and that methionine sulfoxide reductases play a central role in maintaining reduced free methionine pools. Together, this work establishes fMObB as a generalizable strategy for probing free methionine redox states in cellular systems.
dlvr.it
October 6, 2026 at 11:01 PM
"Une « fausse vitamine B12 » pour transformer une résistance tumorale en vulnérabilité" sur @france.theconversation.com
Une « fausse vitamine B12 » pour transformer une résistance tumorale en vulnérabilité
Un nouveau traitement anticancéreux, ciblant deux nutriments, la vitamine B12 et la méthionine, montre une efficacité dans de nombreux cancers.
theconversation.com
October 6, 2026 at 8:21 PM
An oxidized active-site histidine can't be repaired. An oxidized methionine can. Human RNase 1 packs five methionines around its catalytic histidines – remove two and it oxidizes twice as readily. Raines Group, MIT.
October 6, 2026 at 2:22 PM
When using limited amounts of seeds, we could see density for the methionine at position 337, confirming that we had indeed solved the structure of the seeded aggregates. However, we could also solve the structure of the seeds when using more seeds. This is an important warning for future studies.
October 6, 2026 at 10:03 AM
Methionine Market: Trends, Growth & Opportunities 2026–2034

www.intelmarketresearch.com/methionine-m...
Methionine Market 2026 to 2034
Global Methionine market was valued at USD 6.8 billion in 2025 and is projected to reach USD 9.8 billion by 2034, at a CAGR of 4% during the forecast period
www.intelmarketresearch.com
October 5, 2026 at 10:36 AM
Felis catus requires taurine; their gut lacks cysteine and methionine to synthesize it. Synbio can close this gap: precision fermentation producing animal-identical taurine without slaughtering. Watch Ginkgo or Zymergen's next strain release, not the latest cat food trend.
October 4, 2026 at 2:15 PM
You're both wrong, it is methionine
WRONG

L-alanine is the hottest amino acid
Which character of friends is which amino acid?

Monica-proline-Always tied up in knots
Rachel- valine- the hottest amino acid
Chandler-glu or asp- acidic personality

Ross-tryptophan- the nerdiest aa, I bet you didn’t know it is W
Joey- glycine. Empty head no thoughts
Phoebe- ornithine obviously
October 2, 2026 at 4:24 AM
Which pathways drive #adipose browning during #cachexia (#metabolic wasting linked to chronic illness)?

With help from Promethion Metabolic Cages, a Nature #Cancer study revealed a key regulatory iron-dependent pathway.

buff.ly/QBXoCkB

#Metabolism #Physiology #Oncology #IndirectCalorimetry
An iron-regulated methionine redox axis governs adipose browning and cancer cachexia - Nature Cancer
Chio and colleagues describe an iron-dependent pathway with a role in the induction of cancer cachexia-linked events such as adipose browning and identify methionine sulfoxide reductase A as an…
www.nature.com
September 29, 2026 at 6:45 PM
(A Chem) Middle-Down Mass Spectrometry Characterization of
Monoclonal Antibody Enabled by Electron-Activated Dissociation on
a Time-of-Flight Platform: A Case Study of Methionine Oxidation PTM
Identification and Quantification: AbstractCharacterizing
post-translational modifications… #MassSpecRSS
Middle-Down Mass Spectrometry Characterization of Monoclonal Antibody Enabled by Electron-Activated Dissociation on a Time-of-Flight Platform: A Case Study of Methionine Oxidation PTM Identification and Quantification
AbstractCharacterizing post-translational modifications (PTMs) in monoclonal antibody products is critical for ensuring product quality attributes understanding and monitoring. While the bottom-up approach is widely adopted, it suffers from the loss of molecular connectivity and is susceptible to artifact generation. Conversely, top-down approaches face limitations due to the high complexity and poor gas-phase fragmentation of large intact molecules to get site-specific post-translational information profiling. Middle-down MS methods offer a complementary middle-ground approach to both bottom-up and top-down, with broader sequence coverage, and facilitate the simultaneous identification of multiple attributes and proteoforms. In this study, we optimized the electron-activated dissociation (EAD) approach for middle-down sequencing of NISTmAb subunits and present a potential MS and MS/MS strategy to rapidly characterize PTMs on antibodies, using methionine oxidation as an example. Peroxide-stressed and control mAb samples were digested and reduced into subunits using the IdeS enzyme and analyzed via LC-MS, with the optimized MRMHR EAD method. The resulting data enabled high-resolution subunit mass analysis, sequence confirmation, and potential for site-specific oxidation localization. Methionine oxidation localization in NISTmAb was achieved in light chain (M4), Fd’ (M34, M101), and Fc/2 (M16, M122, M192), with these locations confirmed with bottom-up peptide mapping data. Quantification using the Fc/2 subunit enabled detection of oxidation levels up to 1% relative, with strong correlation (R2 > 0.99) between expected and observed values using MS1 data. This middle-down electron-activated dissociation (EAD) approach provides a potential method for site-specific characterization of PTMs in antibody products, offering valuable complementary mapping to support formulation development and production.
dlvr.it
September 29, 2026 at 1:13 PM
In this case specific. As a example: a defined MYB TF regulates the expression of genes for methionine biosynthesis.
September 29, 2026 at 11:52 AM
Even initiator methionine tRNA genes were interesting.
One or more individual iMet tRNA genes emerged as fitness hits in 293T and BJ-hTERT cells BUT none did in two glioblastoma models we tested. Somewhat unexpected given the unique role of iMet tRNAs in translation initiation.
September 28, 2026 at 9:07 AM
So why then, pray tell, do herbivores like cows, bison, elk, moose, etc. develop the largest muscle mass? How do they process protein? And why so many empirical peer reviewed studies that confirm a vegan, vegetarian or Mediterranean diet (with LESS protein) the best for overall health and longevity?
September 28, 2026 at 1:19 AM
So why then, pray tell, do herbivores like cows, bison, elk, moose, etc. develop the largest muscle mass? How do they process protein? And why so many empirical peer reviewed studies that confirm a vegan/vegetarian or Mediterranean diet (with LESS protein) the best for overall health and longevity?
Amino acid-supplemented ‘longevity diet’ linked to longer healthy lifespan
USC study: Diet, small amounts of amino acid methionine increased healthy lifespan.
share.google
September 28, 2026 at 1:18 AM
A modified Mediterranean-style diet with low protein and restricted methionine extended lifespan, reduced body fat, and decreased frailty …

#Ageingresearch #Longevity #Mediterraneandiet #Metabolichealth #Proteinrestriction

#Ageingresearch #Longevity #Mediterraneandiet #Metabolichealth #Proteinr…
Low-Protein Diet Shows Promise for Longevity
A modified Mediterranean-style diet with low protein and restricted methionine extended lifespan, reduced body fat, and decreased frailty … #Ageingresearch #Longevity #Mediterraneandiet #Metabolichealth #Proteinrestriction
news.gmj.ge
September 27, 2026 at 9:26 AM
A MIC shot is methionine, inositol, choline, usually with B12. Every ingredient has a real job in the body. None has a trial showing weight loss in people who are not deficient. The diet bundled with it does the work. glphelper.com/blog/what-are-lipotropic-injections
September 25, 2026 at 11:00 PM
#VNS
Aqueous humor metabolomics links methionine-cycle dysregulation and reduced betaine to proliferative diabetic retinopathy and microvascular alterations.
Details: https://www.maxapress.com/article/doi/10.48130/vns-0026-0038
#DiabeticRetinopathy #Metabolomics #Betaine #Retina
September 25, 2026 at 8:59 AM