#Syndrome_T, i.e. persistent symptoms and reduced #QoL despite normal #TSH concentration, affects 10% of #hypothyroid patients on #levothyroxine. Careful, multimodal and personalised treatment can result in significantly improved outcomes.

#hypothyroidism #thyroid #SORSHOT

doi.org/10.1007/978-...

Growing evidence supports a role of sensorimotor and autonomic #neuropathy in #syndrome_T or #SORSHOT, i.e. reduced quality of life in treated #hypothyroidism. #SPINA_GT and #SPINA_GD predict nerve function and depression.

pubmed.ncbi.nlm.nih.gov/38811750/

doi.org/10.1038/s415...

Our newest paper provides new insights into the conundrum of #syndrome_T / #SORSHOT. #Anxiety and #depression are significantly more common in autoimmune #thyroiditis compared to healthy controls. 🧪🩺

#thyroid #qol

doi.org/10.1038/s415...

Is reduced quality of life in #hypothyroidism a psychological issue? A poster presented at #ECE2023 suggests this. It is, however, impossible to prove causality in a case-control study. We need prospective studies to understand #syndrome_T / #SORSHOT. doi.org/10.1530/endo...

Does impaired transport of #thyroid hormones into the central nervous system contribute to #syndrome_T / #SORSHOT? A recent study observed CSF/serum FT4 ratio to be associated with #QoL in treated #hypothyroidism. doi.org/10.1111/jne....

Einladung zur 2. Endokrinologischen Abendsprechstunde "Up-to-date Schilddrüse 2024" am 25. September 2024. 🩺

#Schilddrüse #Nebenschilddrüse #Hypothyreose #Schilddrüsenchirurgie #Syndrom_T #SORSHOT

www.endokrinologie.org/resources/fl...

#endosky one of most rewarding to treat in endocrinology is figuring out SORSHOT (syndrome of residual symptoms of hypothyroidism on T4). Role of DIO2 polymorphism : Ala92-DIO2 is very common and potential for pathologic role including ER stress www.jci.org/articles/vie...