#Septin
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sergemostowylab.bsky.social
Septin binding restricts Shigella growth and triggers intracellular tolerance

www.pnas.org/doi/10.1073/...
Septin binding restricts Shigella growth and triggers intracellular tolerance | PNAS
Pathogen survival relies on their ability to adapt to changing environments, yet how intracellular bacteria tolerate cell-autonomous immunity remai...
www.pnas.org
November 2, 2026 at 10:59 AM
robertarkowitz.bsky.social
Septin binding restricts Shigella growth and triggers intracellular tolerance | PNAS www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
November 4, 2026 at 9:20 AM
jcb.org
Mechanically induced #septin networks protect nuclear integrity. New study by Margaret E. Utgaard @maggieutgaard.bsky.social, Jordan R. Beach @myosincity.bsky.social, Patrick W. Oakes @pwoakes.bsky.social and colleagues @loyolachicago.bsky.social:
rupress.org/jcb/article/...
#Migration #Cytoskeleton
October 29, 2026 at 2:45 PM
jcb.org
#Septins buffer #actomyosin forces to protect the #nucleus from genotoxic mechanical stress. new study from Franklin Mayca Pozo, Elias T. Spiliotis @septinlab.bsky.social and colleagues:
rupress.org/jcb/article/...

#Cytoskeleton #Cancer #Mechanobiology #Septin #Actin
October 29, 2026 at 2:31 PM
jcb.org
See the related study from Franklin Mayca Pozo, Elias T. Spiliotis et al. @septinlab.bsky.social: rupress.org/jcb/article/...
Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress
Mayca Pozo et al. show that septin filaments are a mechanoprotective cytoskeletal element, buffering actomyosin forces to cushion the nucleus during confin
rupress.org
October 29, 2026 at 2:45 PM
jcb.org
See the related study from @maggieutgaard.bsky.social, @myosincity.bsky.social, @pwoakes.bsky.social et al. rupress.org/jcb/article/...
Mechanically induced septin networks protect nuclear integrity
Utgaard et al. show that septins accumulate at the cortex in response to mechanical cues, where they serve to buffer mechanical forces that act on the nucl
rupress.org
October 29, 2026 at 2:31 PM
auggiethebeck.bsky.social
Leo dis iz grate Ideer!! Septin who took an pikshure of youse iffin youse sitten on tha fone? 😸🤍🤎
October 28, 2026 at 2:12 AM
anhhle2702.bsky.social
Beautiful paper from the @pwoakes.bsky.social lab. Stunning imaging, I love the experimental design, very intuitive. Pressing a glass bead on cytoplast induces Septin filaments is so cool! I always believe the best science is when you can answer with a simple experiment. doi.org/10.1083/jcb....
October 23, 2026 at 8:35 PM
septinlab.bsky.social
Septin cytoskeleton acts like intermediate filaments!

Our & @pwoakes.bsky.social newest papers in @jcb.org show septins relieve mechanical stress, a key oncogenic trait that can help metastatic tumors survive.

Exciting translational implications, a new player in mechanobiology, sick imaging!
jcb.org Journal of Cell Biology @jcb.org · 15d
New work from Mayca Pozo et al. @septinlab.bsky.social reshapes #septin biology: septins relieve #actomyosin forces, shielding #actin & the #nucleus from mechanical damage. SEPT9 overexpression may promote tumor cell survival by limiting genomic damage during #metastasis. rupress.org/jcb/article/...
October 23, 2026 at 12:51 AM
cellclub.bsky.social
Mechanically induced septin networks protect nuclear integrity rupress.org/jcb/article-...
Mechanically induced septin networks protect nuclear integrity
Utgaard et al. show that septins accumulate at the cortex in response to mechanical cues, where they serve to buffer mechanical forces that act on the nucl
rupress.org
October 22, 2026 at 2:50 PM
jcb.org
New work from Mayca Pozo et al. @septinlab.bsky.social reshapes #septin biology: septins relieve #actomyosin forces, shielding #actin & the #nucleus from mechanical damage. SEPT9 overexpression may promote tumor cell survival by limiting genomic damage during #metastasis. rupress.org/jcb/article/...
October 22, 2026 at 4:31 PM
robertarkowitz.bsky.social
rupress.org/jcb/article/...
Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress
Mayca Pozo et al. show that septin filaments are a mechanoprotective cytoskeletal element, buffering actomyosin forces to cushion the nucleus during confin
rupress.org
October 22, 2026 at 6:20 PM
jcb.org
See the related study from @maggieutgaard.bsky.social, @myosincity.bsky.social, @pwoakes.bsky.social et al. rupress.org/jcb/article/...
Mechanically induced septin networks protect nuclear integrity
Utgaard et al. show that septins accumulate at the cortex in response to mechanical cues, where they serve to buffer mechanical forces that act on the nucl
rupress.org
October 22, 2026 at 4:31 PM
cellclub.bsky.social
Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress rupress.org/jcb/article/...
Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress
Mayca Pozo et al. show that septin filaments are a mechanoprotective cytoskeletal element, buffering actomyosin forces to cushion the nucleus during confin
rupress.org
October 22, 2026 at 2:47 PM
rupress.org
See the related study from @maggieutgaard.bsky.social, @myosincity.bsky.social, @pwoakes.bsky.social et al. rupress.org/jcb/article/...
Mechanically induced septin networks protect nuclear integrity
Utgaard et al. show that septins accumulate at the cortex in response to mechanical cues, where they serve to buffer mechanical forces that act on the nucl
rupress.org
October 22, 2026 at 5:15 PM
robertarkowitz.bsky.social
rupress.org/jcb/article/...
Mechanically induced septin networks protect nuclear integrity
Utgaard et al. show that septins accumulate at the cortex in response to mechanical cues, where they serve to buffer mechanical forces that act on the nucl
rupress.org
October 22, 2026 at 6:19 PM
jcb.org
See the related study from Mayca Pozo et al. @septinlab.bsky.social: rupress.org/jcb/article/...
Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress
Mayca Pozo et al. show that septin filaments are a mechanoprotective cytoskeletal element, buffering actomyosin forces to cushion the nucleus during confin
rupress.org
October 22, 2026 at 5:01 PM
rupress.org
New work in @jcb.org from @septinlab.bsky.social reshapes #septin biology: septins relieve #actomyosin forces, shielding #actin & the #nucleus from mechanical damage. SEPT9 overexpression may promote tumor cell survival by limiting genomic damage during #metastasis. rupress.org/jcb/article/...
October 22, 2026 at 5:15 PM
rupress.org
See the related study from Mayca Pozo et al. @septinlab.bsky.social: rupress.org/jcb/article/...
Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress
Mayca Pozo et al. show that septin filaments are a mechanoprotective cytoskeletal element, buffering actomyosin forces to cushion the nucleus during confin
rupress.org
October 22, 2026 at 5:30 PM
rridrobot.bsky.social
The authors included RRIDs in their in Molecular Biology of the Cell paper! RRIDs improve reproducibility in scientific research. #OpenScience #reproducibility #STMpublishing
Local RhoA activation induces anillin-independent septin recruitment in interphase cells
Read the full paper: Local RhoA activation induces anillin-independent septin recruitment in interphase cells
doi.org
October 9, 2026 at 7:10 AM
Budding yeast Bud3 and Bud4 cooperatively organize septin architecture and support cytokinetic spatial memory: Cell Reports www.cell.com/cell-reports...
Budding yeast Bud3 and Bud4 cooperatively organize septin architecture and support cytokinetic spatial memory
Using in vitro reconstitution assays and live-cell imaging, Adriaans et al. show how Bud3 and Bud4 drive septin double-ring assembly at the budding yeast division site during cytokinesis. Their findin...
www.cell.com
October 7, 2026 at 1:02 PM
aoihal-ppbot.bsky.social
Brieuc Chauvin, Luca Costa, Martin Lenz, Bassam Hajj, Pierre-Emmanuel Milhiet, Stéphanie Mangenot, Aurélie Bertin: Unexpected softening of giant unilamellar vesicles by budding yeast septin filaments: a curvature dependent mechanism https://hal.science/hal-05779505v1 [phys]
October 7, 2026 at 3:00 AM
cp-cellreports.bsky.social
Budding yeast Bud3 and Bud4 cooperatively organize septin architecture and support cytokinetic spatial memory
Budding yeast Bud3 and Bud4 cooperatively organize septin architecture and support cytokinetic spatial memory
Using in vitro reconstitution assays and live-cell imaging, Adriaans et al. show how Bud3 and Bud4 drive septin double-ring assembly at the budding yeast division site during cytokinesis. Their findings also reveal how these proteins establish a septin-dependent memory of cytokinesis, providing insight into the mechanisms underlying division-site organization and inheritance.
dlvr.it
September 26, 2026 at 2:38 PM
robertarkowitz.bsky.social
www.molbiolcell.org/doi/abs/10.1...
Deletion of core septin gene aspB in Aspergillus fumigatus results in fungicidal activity of caspofungin | Molecular Biology of the Cell
Septins are a family of GTP-binding proteins found in many eukaryotic lineages. Although highly conserved throughout many eukaryotes, their functions vary across species. In Aspergillus fumigatus, the...
www.molbiolcell.org
September 17, 2026 at 8:08 AM
septinlab.bsky.social
September is for Septins!

#SeptforSeptins

Time for septin spice lattes... and submitting your septin paper to the MBoC Special Issue: Cell Biology of Septins

Still accepting papers @ascbiology.bsky.social

www.molbiolcell.org/cell-biology...
Molecular Biology of the Cell (MBoC)
www.molbiolcell.org
September 15, 2026 at 11:15 AM