Roby, N., Rauzi, M. (2025). Nuclear position controls the activity of cortical actomyosin networks powering simultaneous morphogenetic events. Nature communications, 16(1):1587 www.nature.com/articles/s41...
Nuclear position controls the activity of cortical actomyosin networks powering simultaneous morphogenetic events - Nature Communications
Embryo gastrulation involves multiple simultaneous morphogenetic transformations that must be coordinated. Here, the authors show that nuclear migration acts as a spatiotemporal regulator of the cytos...
www.nature.com
November 5, 2026 at 10:19 PM
Roby, N., Rauzi, M. (2025). Nuclear position controls the activity of cortical actomyosin networks powering simultaneous morphogenetic events. Nature communications, 16(1):1587 www.nature.com/articles/s41...
Rac1 restrains actomyosin to enable ciliogenesis and mechanosensing in the postnatal kidney rupress.org/jcb/article-...
Rac1 restrains actomyosin to enable ciliogenesis and mechanosensing in the postnatal kidney
Bayazid et al. show that Rac1 deletion in mice causes postnatal cystic dysplasia resembling human multicystic dysplastic kidney disease. Rac1 organizes the
rupress.org
November 4, 2026 at 8:26 PM
Rac1 restrains actomyosin to enable ciliogenesis and mechanosensing in the postnatal kidney rupress.org/jcb/article-...
Systematic comparison of genetically encoded F-actin probes for visualizing actomyosin dynamics in vivo using C. elegans https://www.biorxiv.org/content/10.64898/2026.11.03.763946v1
November 4, 2026 at 1:30 PM
Systematic comparison of genetically encoded F-actin probes for visualizing actomyosin dynamics in vivo using C. elegans https://www.biorxiv.org/content/10.64898/2026.11.03.763946v1
Interestingly, we find that calcium flashes drive the localized, pulsatile actomyosin contractility required for efficient tricellular zipping.
Calbae Calcium
ALT: Calbae Calcium
static.klipy.com
November 4, 2026 at 4:58 PM
Interestingly, we find that calcium flashes drive the localized, pulsatile actomyosin contractility required for efficient tricellular zipping.
Calcium and actomyosin pulses drive tricellular zipping to remodel epithelial cell-cell junctions and facilitate cell packing https://www.biorxiv.org/content/10.64898/2026.10.30.763104v1
November 4, 2026 at 7:31 AM
Calcium and actomyosin pulses drive tricellular zipping to remodel epithelial cell-cell junctions and facilitate cell packing https://www.biorxiv.org/content/10.64898/2026.10.30.763104v1
Combining modeling and live imaging approaches, we find that displacement of the remodeling vertex depends on actomyosin-dependent asymmetric force generation and on enrichment of adaptor proteins coupling actomyosin to junctions, which enables effective force transmission.
November 4, 2026 at 4:58 PM
Combining modeling and live imaging approaches, we find that displacement of the remodeling vertex depends on actomyosin-dependent asymmetric force generation and on enrichment of adaptor proteins coupling actomyosin to junctions, which enables effective force transmission.
Systematic comparison of genetically encoded F-actin probes for visualizing actomyosin dynamics in vivo using C. elegans https://www.biorxiv.org/content/10.64898/2026.11.03.763946v1
November 4, 2026 at 1:30 PM
Systematic comparison of genetically encoded F-actin probes for visualizing actomyosin dynamics in vivo using C. elegans https://www.biorxiv.org/content/10.64898/2026.11.03.763946v1
Calcium and actomyosin pulses drive tricellular zipping to remodel epithelial cell-cell junctions and facilitate cell packing https://www.biorxiv.org/content/10.64898/2026.10.30.763104v1
November 4, 2026 at 7:31 AM
Calcium and actomyosin pulses drive tricellular zipping to remodel epithelial cell-cell junctions and facilitate cell packing https://www.biorxiv.org/content/10.64898/2026.10.30.763104v1
YAP/TAZ read matrix stiffness and cell shape 💪 A stiff matrix or a spread cell ➡️ YAP in the nucleus; a soft matrix or a small cell ➡️ YAP in the cytoplasm. This needs Rho and actomyosin tension but not the Hippo kinases.
doi.org/10.1038/natu...
doi.org/10.1038/natu...
November 8, 2026 at 8:00 AM
YAP/TAZ read matrix stiffness and cell shape 💪 A stiff matrix or a spread cell ➡️ YAP in the nucleus; a soft matrix or a small cell ➡️ YAP in the cytoplasm. This needs Rho and actomyosin tension but not the Hippo kinases.
doi.org/10.1038/natu...
doi.org/10.1038/natu...
www.biorxiv.org/content/10.6...
Mechanoadaptive focal adhesion–actomyosin coupling organizes diverse modes across ECM stiffness
Mechanoadaptive focal adhesion–actomyosin coupling organizes diverse modes across ECM stiffness
October 31, 2026 at 12:00 PM
www.biorxiv.org/content/10.6...
Mechanoadaptive focal adhesion–actomyosin coupling organizes diverse modes across ECM stiffness
Mechanoadaptive focal adhesion–actomyosin coupling organizes diverse modes across ECM stiffness
RRIDs were included in this in Nature Communications paper. We value the author's support of reproducibility. #methodsmatter #accelerateopenscience #RRID
InsP3R signaling and actomyosin-dependent mitochondrial dynamics play essential roles in mitochondrial stress-induced longevity - Nature Communications
Mitochondrial perturbations confer longevity or disease depending on if cells successfully adapt. Here, the authors show that ER calcium signalling promotes longevity during mitochondrial stress by regulating actin-dependent mitochondrial remodeling.
doi.org
November 8, 2026 at 8:02 AM
RRIDs were included in this in Nature Communications paper. We value the author's support of reproducibility. #methodsmatter #accelerateopenscience #RRID
See the related study from Franklin Mayca Pozo, Elias T. Spiliotis et al. @septinlab.bsky.social: rupress.org/jcb/article/...
Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress
Mayca Pozo et al. show that septin filaments are a mechanoprotective cytoskeletal element, buffering actomyosin forces to cushion the nucleus during confin
rupress.org
October 29, 2026 at 2:45 PM
See the related study from Franklin Mayca Pozo, Elias T. Spiliotis et al. @septinlab.bsky.social: rupress.org/jcb/article/...
#Septins buffer #actomyosin forces to protect the #nucleus from genotoxic mechanical stress. new study from Franklin Mayca Pozo, Elias T. Spiliotis @septinlab.bsky.social and colleagues:
rupress.org/jcb/article/...
#Cytoskeleton #Cancer #Mechanobiology #Septin #Actin
rupress.org/jcb/article/...
#Cytoskeleton #Cancer #Mechanobiology #Septin #Actin
October 29, 2026 at 2:31 PM
#Septins buffer #actomyosin forces to protect the #nucleus from genotoxic mechanical stress. new study from Franklin Mayca Pozo, Elias T. Spiliotis @septinlab.bsky.social and colleagues:
rupress.org/jcb/article/...
#Cytoskeleton #Cancer #Mechanobiology #Septin #Actin
rupress.org/jcb/article/...
#Cytoskeleton #Cancer #Mechanobiology #Septin #Actin
Mechanoadaptive focal adhesion-actomyosin coupling organizes diverse modes across ECM stiffness https://www.biorxiv.org/content/10.64898/2026.10.26.762083v1
October 30, 2026 at 10:49 PM
Mechanoadaptive focal adhesion-actomyosin coupling organizes diverse modes across ECM stiffness https://www.biorxiv.org/content/10.64898/2026.10.26.762083v1
Mechanoadaptive focal adhesion-actomyosin coupling organizes diverse modes across ECM stiffness https://www.biorxiv.org/content/10.64898/2026.10.26.762083v1
October 30, 2026 at 10:49 PM
Mechanoadaptive focal adhesion-actomyosin coupling organizes diverse modes across ECM stiffness https://www.biorxiv.org/content/10.64898/2026.10.26.762083v1
Understanding How Actomyosin Dynamics Drive Apical Constriction by Systematically Tagging and Mapping Actin-Binding Proteins https://www.biorxiv.org/content/10.64898/2026.10.23.761371v1
October 27, 2026 at 10:30 AM
Understanding How Actomyosin Dynamics Drive Apical Constriction by Systematically Tagging and Mapping Actin-Binding Proteins https://www.biorxiv.org/content/10.64898/2026.10.23.761371v1
Understanding How Actomyosin Dynamics Drive Apical Constriction by Systematically Tagging and Mapping Actin-Binding Proteins https://www.biorxiv.org/content/10.64898/2026.10.23.761371v1
October 27, 2026 at 10:30 AM
Understanding How Actomyosin Dynamics Drive Apical Constriction by Systematically Tagging and Mapping Actin-Binding Proteins https://www.biorxiv.org/content/10.64898/2026.10.23.761371v1
Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress rupress.org/jcb/article/...
Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress
Mayca Pozo et al. show that septin filaments are a mechanoprotective cytoskeletal element, buffering actomyosin forces to cushion the nucleus during confin
rupress.org
October 22, 2026 at 2:47 PM
Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress rupress.org/jcb/article/...
New work from Mayca Pozo et al. @septinlab.bsky.social reshapes #septin biology: septins relieve #actomyosin forces, shielding #actin & the #nucleus from mechanical damage. SEPT9 overexpression may promote tumor cell survival by limiting genomic damage during #metastasis. rupress.org/jcb/article/...
October 22, 2026 at 4:31 PM
New work from Mayca Pozo et al. @septinlab.bsky.social reshapes #septin biology: septins relieve #actomyosin forces, shielding #actin & the #nucleus from mechanical damage. SEPT9 overexpression may promote tumor cell survival by limiting genomic damage during #metastasis. rupress.org/jcb/article/...
See the related study from Mayca Pozo et al. @septinlab.bsky.social: rupress.org/jcb/article/...
Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress
Mayca Pozo et al. show that septin filaments are a mechanoprotective cytoskeletal element, buffering actomyosin forces to cushion the nucleus during confin
rupress.org
October 22, 2026 at 5:01 PM
See the related study from Mayca Pozo et al. @septinlab.bsky.social: rupress.org/jcb/article/...
See the related study from Mayca Pozo et al. @septinlab.bsky.social: rupress.org/jcb/article/...
Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress
Mayca Pozo et al. show that septin filaments are a mechanoprotective cytoskeletal element, buffering actomyosin forces to cushion the nucleus during confin
rupress.org
October 22, 2026 at 5:30 PM
See the related study from Mayca Pozo et al. @septinlab.bsky.social: rupress.org/jcb/article/...
@thermofishersci.bsky.social's resource, RRID:AB_2533438, was just reported to be used in the paper. We value the author's support of reproducibility. #OpenScience #ReproducibleResearch #RRID
FGD1 restrains actomyosin contractility to promote suprabasal junction maturation in stratified keratinocytes
Read the full paper: FGD1 restrains actomyosin contractility to promote suprabasal junction maturation in stratified keratinocytes
doi.org
October 23, 2026 at 7:03 AM
@thermofishersci.bsky.social's resource, RRID:AB_2533438, was just reported to be used in the paper. We value the author's support of reproducibility. #OpenScience #ReproducibleResearch #RRID